Jakub Sikora finished his M.D./Ph.D. training in Cell Biology and Pathology at the Institute of Inherited Metabolic Diseases (1st Faculty of Medicine – Charles University in Prague, Czech Republic) in 2007.
In the years 2011-2014, Dr. Sikora worked as an international neuroscience research fellow (supported by the National Institute of Neurological Diseases and Stroke - NINDS) in the laboratories of Dr. Steven U. Walkley and Dr. Kostantin Dobrenis at the Dominick D. Purpura Department of Neuroscience of Albert Einstein College of Medicine (Bronx, NY).
Currently, Dr. Sikora serves as an assistant professor and vice-chairman for graduate studies at the Department of Pediatrics and Adolescent Medicine (1st Faculty of Medicine – Charles University).Dr. Sikora also provides specialized histopathological and ultrastructural expertise in diagnostics of rare diseases.
In close collaboration with Drs. Walkley and Dobrenis, Dr. Sikora pursues research projects aimed at (neuro)pathogenesis and experimental therapies of rare endosomal/lysosomal monogenic diseases. He specifically focuses on Danon disease (LAMP2 def.), Christianson syndrome (SLC9A6 def.), Niemann-Pick type A/B (acid sphingomyelinase def.) and C diseases and Farber disease (acid ceramidase def.).