Department of Orthopaedic Surgery

5th Annual Musculoskeletal Repair and Regeneration Symposium

[Download the program brochure] 

SYMPOSIUM MISSION 

The Albert Einstein College of Medicine Musculoskeletal Repair and Regeneration Symposium seeks to expand the knowledge base within the field, and to foster creativity, collaboration and networking between researchers throughout the region. This year's meeting will emphasize recent advances in translational research in four areas:

   • Stem cells and tissue repair: in tendon and beyond
   • Novel views into the disc and other degenerative diseases
   • New insights in arthritis
   • Bone adaption in aging and disease
 

CONFERENCE LOCATION AND DATE  

October 13, 2016
LeFrak Auditorium (Room 151)
Albert Einstein College of Medicine
1301 Morris Park Ave. Bronx, NY 10461
Directions: http://www.einstein.yu.edu/visitors/   


REGISTRATION   

Deadline: October 10, 2016
Registration includes continental breakfast, lunch, and reception.
Registration is free. Early registration is highly recommended.
Click here to register 

AGENDA 

7:15 – 8:00am

Check-in and continental breakfast

8:00 – 8:10am

Opening remarks
Neil J. Cobelli, M.D.

Session 1: Stem cells and tissue repair and regeneration: in tendon and beyond 

Steering Chair: Helen Lu, Ph.D.

8:10-8:35am

Evaluation of Tendon-Specific Endothelial-Derived Stem Cells in Rotator Cuff Repair
Scott Rodeo, M.D.
The Hospital for Special Surgery

8:35-9:00am

 

Stem Cells and Skeletal Muscle Tissue Engineering
Johnny Huard, Ph.D.
University of Texas Health Science Center at Houston

9:00-9:25am

 

Regulation of tendon regeneration
Alice Huang, Ph.D.
Icahn School of Medicine at Mount Sinai

9:25-9:50am

Tendon / cartilage differentiation and regeneration
Hongwei Ouyang, M.D., Ph.D.
Zhejiang University, China

9:50-10:10am

Coffee Break

 

Session 2: New insights in arthritis 

Steering Chair: John Hardin, M.D.

10:10-10:30am

 

Autoimmunity in Juvenile Idiopathic Arthritis
Laura Santambrogio, Ph.D.
Albert Einstein College of Medicine

10:30-10:50am

 

Regulation of inflammatory responses in tumor necrosis factor-activated and rheumatoid arthritis synovial macrophages by JAK inhibitors
Lionel Ivashkiv, M.D.
The Hospital for Special Surgery

10:50-11:10am

 

Beta-catenin is a Key Mediator in the Development of Spondyloarthritis
Di Chen, Ph.D.
Rush University

11:10-11:30am

 

Energy sensor AMPK in cartilage homeostasis and osteoarthritis
Ru Liu-Bryan, Ph.D.
University of California, San Diego

11:30-11:50am

 

TGF-beta signaling in bone and cartilage
Xu Cao, Ph.D.
Johns Hopkins University

 

Lunch and poster session 

12:00-1:45pm

 

Lunch and poster session
      Poster session starts at 12:45pm
12:00pm – Faculty photo
12:00-12:45pm – Faculty meeting with lunch
 
 

Session 3: Novel views into musculoskeletal degenerative diseases  

Steering Chair: James Iatridis, Ph.D.

1:45-2:10pm

 

Elucidating Mechanisms of Tendon Damage by Measuring Multiscale Unloaded Recovery Following Tensile Loading
Dawn Elliott, Ph.D.
University of Delaware

2:10-2:35pm

 

In search of biomarkers of back pain: systemic cytokine profiles in patients with intervertebral disc disorders
Nadeen Chahine, Ph.D.
The Feinstein Institute for Medical Research

2:35-3:00pm

 

Insights into a novel autophagic pathway in nucleus pulposus cells
Makarand V. Risbud, Ph.D.
Thomas Jefferson University

3:00-3:25pm

 

Injury, inflammation, and altered mechanotransduction in the intervertebral disc
James Iatridis, Ph.D.
Icahn School of Medicine at Mount Sinai

3:25-3:45pm

 

Coffee Break

Session 4: Bone Adaptation in Aging and Disease 

Steering Chair: Susannah Fritton, Ph.D.

3:45-4:05pm

 

Bone mineralization changes due to aging and disease
Adele Boskey, Ph.D.
Hospital for Special Surgery

4:05-4:25pm

 

Effects of bone matrix proteins on fracture and fragility
Deepak Vashishth, Ph.D.
Rensselaer Polytechnic Institute

4:25-4:45pm

 

Mechanical adaptation of the skeleton during homeostasis and repair
Alesha Castillo, Ph.D.
New York University

4:45-5:05pm

 

Role of estrogen signaling in load-based skeletal adaptation
Marjolein van der Meulen, Ph.D.
Cornell University

5:05-5:25pm

Low magnitude mechanical signals as an anabolic signal to the skeleton in aging and disease
Clint Rubin, Ph.D.
Stony Brook University
 
 

Young Investigator Awards / Reception 

5:30pm

 

Young Investigator Awards
Chair: Mia M. Thi, PhD

5:45pm

Closing remarks
Neil J. Cobelli, MD

5:45pm – 6:15pm

Reception and networking

 

PROGRAM COMMITTEE  

Hui B. Sun, PhD - Program Director

Steering Commitee Chairs
• Helen Lu, PhD
• James Iatridis, PhD
• John Hardin, MD
• Susannah Fritton, PhD

Program Overseers 
• Di Chen, PhD
• Mary Goldring, PhD
• Ed Guo, PhD
• Jeremy Mao, DDS, PhD
• Maurizio Pacifici, PhD
• Yi-Xian Qin, PhD
• Mitchell Schaffler, PhD

Poster Session and Young Investigator Award Committee
• Chair: Mia Thi, PhD

• Co-chair: David Hirsh, MD
• Co-chair: Bang Hoang, PhD
• Co-chair: Robert J. Majeska, PhD
• Co-chair: Jeremy J. Mao, DDS, PhD
• Co-chair: Maurizio Pacifici, PhD
• Co-chair: Sylvia O. Suadicani, PhD 

CALL FOR ABSTRACTS / YOUNG INVESTIGATOR AWARD 

Poster Session - We invite investigators to submit abstracts for the poster session, which is an important component of this conference. Posters will be displayed throughout the day with a dedicated poster session. Young Investigator Award Abstracts from students at all training levels and postdoctoral fellows will be considered for Young Investigator Awards. Three winners will be announced and each will be presented with prize and a plaque during the evening session. Winners will have the opportunity to give a brief highlight of their work (2 minutes) at the end of the award ceremony.

To qualify, you must register and submit an abstract to Dr. Mia Thi, the chair of the Poster Session and Young Investigator Award committee, by September 26, 2016 via email to: mia.thi@einstein.yu.edu. 

The abstract is limited to 1 page. Include in your abstract the study's objective, a brief statement of methods, a summary of the results obtained, conclusions, and significance. Please follow the template here. As the Symposium aims to promote communication within our region, we encourage you to submit your recent work (within 2016) to this Symposium, including work that may have been submitted to other meetings.

 

STATEMENT OF NEED  

Damage to musculoskeletal tissues is a significant cause of morbidity and increased mortality, and is a magnifier of mortality in other clinical diseases such as diabetes and cardiovascular disorders. The innate repair capacities are limited for articular cartilage, tendon, and extensive bone defects. In addition, current treatments for the repair of injured musculoskeletal tissue are not sufficient to restore the functionality of the original tissue. These daunting challenges present a desperate need for a better understanding of musculoskeletal biology and emphasize the importance of discovering novel repair and regeneration strategies that can be translated to clinical use.

GOALS  

This program will address current issues in musculoskeletal repair and regeneration, and disease treatment. Discussions will focus on up-to-date laboratory discoveries and the potential impact of these findings on patient treatment and management in the future.

CONTACT INFORMATION 

Herb B. Sun, PhD
 Program Director
 Email: herb.sun@einstein.yu.edu
 P: 718-430-4291
 F: 718-430-3259 

Mia M. Thi, PhD
 Chair, Poster Session and Young Investigator
 Award Committee
 Email: mia.thi@einstein.yu.edu
 P: 718-430-3460 

Rhomina Carrasco
 Symposium Coordinator
 Email: rhomina.carrasco@einstein.yu.edu
 P: 718-430-2911 

HOTEL INFORMATION 
Residence Inn by Marriott
The Bronx at Metro Center Atrium
1776 Eastchester Road, Bronx, NY 10461
Launched in May 2015, the hotel is a 10 minute walk from the Symposium.
http://cwp.marriott.com/nycbx 
P: 718-239-3939

PARKING INFORMATION  
The PF Parking lot
1975 Eastchester Road
Bronx, NY 10461
http://einstein.pfparking.org/location.php 

 

Chair:

Neil J. Cobelli, M.D.
neil.cobelli@einstein.yu.edu
Tel: 347.577.4450
Fax: 347.577.4451

Administrator

Anna Cioffi
anna.cioffi@einstein.yu.edu
Tel: 718.430.2911

 

Department Office

Montefiore Medical Center
1250 Waters Place
11th floor
Bronx, NY 10461

Tel: 347.577.4450
Fax:
347.577.4451

 
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