Czaja and Kim Receive Tenure
Two of the four newly tenured faculty members at Einstein this year are members of the Department of Medicine.
Mark J. Czaja, MD
Image: Mark Czaja, MD (Hepatology)
Dr. Mark J. Czaja is Professor of Medicine in the Division of Hepatology at Einstein. Dr. Czaja came to Einstein as a fellow in Gastroenterology/Hepatology in 1983 and joined the faculty in 1987. His research attempts to understand the molecular mechanisms of liver cell injury and death in order to better prevent the hepatic failure that develops from human liver disease. He has discovered that toxic liver injury results from alterations in cell signaling pathways that sensitize liver cells to death from the cytokine tumor necrosis factor, rather than from the direct biochemical effects of the toxin. Dr. Czaja's research also has delineated mechanisms that underlie the development of hepatic lipid accumulation, or steatosis, and its progression to the liver disease known as nonalcoholic steatohepatitis. As part of this work, conducted with Dr. Ana Maria Cuervo at Einstein, he has recently described a novel function for the pathway of autophagy in the regulation of hepatocyte lipid storage. Dr. Czaja received his undergraduate degree from Yale University and his M.D. from the Columbia College of Physicians and Surgeons.
Kami Kim, MD
Image: Kami Kim, MD (Infectious Diseases)
Dr. Kami Kim is Professor of Medicine in the Division of Infectious Diseases and Professor of Microbiology & Immunology. Dr. Kim joined the Einstein faculty in 1995 as an assistant professor, and was promoted to associate professor in 2002 and to professor in 2007. Her research focuses on understanding how the organisms Toxoplasma gondii and Plasmodium species (malaria) cause clinical disease in humans. Using genetic, biochemical, and cell biology approaches, she and colleagues seek to develop new treatments for these parasitic infections, which combined affect more than a half-billion people worldwide. Thus far, Dr, Kim's team has characterized the epigenetic characteristics of Toxoplasma gondii and is developing other initiatives to understand how pathogens influence epigenetic gene expression of infected human cells. They also are investigating potential targets for drug therapy. Dr. Kim received her bachelor's degree from Harvard University and her medical degree from the Columbia College of Physicians and Surgeons. She completed a clinical fellowship in infectious diseases at UCSF, followed by postdoctoral fellowships in parasitology at San Francisco General Hospital-UCSF and in microbiology and immunology at Stanford University. During these fellowships she also served as an attending physician at the San Francisco County Tuberculosis Clinic and at San Francisco General Hospital.
Sincerest congratulations to Drs. Czaja and Kim on this well deserved peer recognition.