From Hypercalcemia of Malignancy to Normal Physiology
Einstein/Montefiore Department of Medicine Grand Rounds
Thursday, April 24, 2014
8:00 AM: Forchheimer Medical Science Building 3rd Floor Lecture Hall
Speaker & Info
Andrew Stewart, MD
Director, Diabetes Obesity and Metabolism Institute
Professor of Medicine, Endocrinology, Diabetes and Bone Disease
Irene and Dr. Arthur M Fishberg Professor
Mount Sinai Medical School
New York, NY
Repeated at 12:15 pm, Cherkasky Auditorium, Montefiore Medical
Dr. Andrew Stewart has led a career devoted to patient care and basic and clinical research in endocrinology and diabetes for over 30 years. He is a leading authority on human pancreatic beta cell replication and regeneration. His research focuses on understanding and developing novel means for inducing beta cell regeneration. His group was the first to demonstrate that growth factors could drive beta cell replication in vivo in mammals, and also improve glucose control in living animals. He was also the first to carefully define cell cycle control in the rodent and human beta cell, and is actively involved in understanding why human beta cells normally do not replicate. His team has been able to induce robust replication in human beta cells, and to reverse diabetes with engineered, rapidly replicating human beta cells in vivo. This work is the subject of invited symposia at both the American Diabetes Association (ADA), the European Islet Study Group (ISG), the European Association for the Study of Diabetes (EASD), the International Congress of Endocrinology, and the US National Institutes of Health.
Dr. Stewart has received numerous honors, including Councilor of both the Endocrine Society as well as the American Society for Bone and Mineral Research (ASBMR); Secretary-Treasurer of the Endocrine Society, and Chair of the Program Committee for the ADA. He has published more than 230 scientific papers, with many in journals of the highest quality, including the Proceedings of the National Academy of Sciences, the New England Journal of Medicine, and Science. Dr. Stewart is the continuous recipient of numerous research grants for the past 30 years. He currently has strong support from the NIH, the JDRF and other agencies. He has served on and chaired grant review panels for the NIH, the ADA and the JDRF. He was the 2008 recipient of the Endocrine Society's Gerald Aurbach Award for outstanding scientific achievement. He served as the Chair of the American Diabetes Association Annual Meetings for 2010 and 2012.
Dr. Stewart received his bachelor's degree from Trinity College in Hartford, Connecticut and his M.D. from Columbia University, College of Physicians and Surgeons, New York, New York. He served as a fellow in Endocrinology and Metabolism at Yale University School of Medicine in Connecticut, and rose to the rank of tenured Professor at Yale. He moved to Pittsburgh in 1997 to become Chief of the Division of Endocrinology and Metabolism at the University of Pittsburgh School of Medicine. He recently moved to New York to serve as the Director of the Diabetes, Obesity and Metabolism Institute at Mount Sinai in November 2012.
After attending this activity, participants will be able to:
- Understand the mechanisms by which common cancers lead to hypercalcemia
- Learn the pathobiology of parathyroid hormone-related protein (PTHrP)
- Discover the normal roles of PTHrP in human biology
Accreditation: Albert Einstein College of Medicine designates this
educational activity for a maximum of 1 credit towards the AMA Physician's
Recognition Award. Each physician should claim only those credits that
he/she actually spent in the educational activity.
Division of Endocrinology (Department of Medicine)