Adam Friedman, MD, FAAD is an Associate Professor of Dermatology and serves as Residency Program Director and Director of Translational Research in the Department of Dermatology at The George Washington University School of Medicine & Health Sciences. Dr. Friedman completed his undergraduate training at the University of Pennsylvania and graduated with Distinction in Dermatologic Research at the Albert Einstein College of Medicine in New York. He completed his internship at New York Hospital Queens, and returned to Einstein for his Dermatology residency and was appointed Chief Resident during his final year. Dr. Friedman joined the Einstein faculty after graduation from 2010-2015, during which time he was the Director of Dermatologic Research, Director of the Translational Research Fellowship, and the Associate Program Director.
Dr. Friedman is currently investigating novel nanotechnologies that allow for controlled and sustained delivery of a wide spectrum of physiologically and medicinally relevant molecules, with an emphasis on treating infectious diseases, accelerating wound healing, immune modulation, and correcting vascular dysfunction. He holds mutliple patents derived from these investigations, and has published over 120 papers/chapters and 2 textbooks on both his research as well as a variety of clinical areas in dermatology with an emphasis on emerging medical therapies. In line with his research interests, he serves as Vice President of the Nanodermatology society and Vice Chair of the Dermatology Section of the New York Academy of Medicine. He has received multiple awards such as the American Dermatologic Association Young Leader Award, the American Society for Dermatologic Surgery Cutting Edge Research Award, the Journal of Drugs in Dermatology Leader in Photoprotection award, the La Roche Posay North American Foundation Research award, and he was voted to New York Times Magazine’s Super Doctors® Rising Stars each year since 2013.
Dr. Friedman is also committed to resident and medical education. He chaired of the leadership workgroup of the American Academy of Dermatology Resident/Fellows Committee, currently serves on the Sulzberger Committee on Education, and is the Senior Editor of the Dermatology In-Review Online Workshop. Dr. Friedman serves as the Dermatology Expert for healthguru.com, publishes a column on Everyday healthy entitled The Skin You're In and in line with his research interests, as the Vice President of the Nanodermatology Society. Dr. Friedman was recently appointed as President of the Dermatology Section of the New York Academy of Medicine.
Dr. Friedman has appeared on television news programs such as Good Morning America, and has been quoted in numerous leading publications, including WebMD, In Style, Reuters, Good Housekeeping, and Women’s Day.
Friedman, A, Han, G, Navati, MH, Chacko, M, Gunther, L, Alfieri, A, Friedman, JM. Sustained Release Nitric Oxide Releasing Nanoparticles: Characterization of a Novel Platform Based on Nitrite Containing Hydrogel/Glass Composites. Nitric Oxide 2008 19(1): 12-20.
Han, G, Zippin, J, Friedman, A. From Bench to Bedside: The Therapeutic Potential of Nitric Oxide in Dermatology. J Drugs Dermatol. 2009; 8(6): 586-591.
Martinez, L, Han, G, Chacko M, Mihu, MR, Jacobson, M, Gialanella, P, Friedman, A, Nosanchuk, J, Friedman, JM. Antimicrobial and Healing Efficacy of Sustained Release Nitric Oxide Nanoparticles against Staphylococcus aureus Skin Infections. J Invest. Dermatol. 2009: 129; 2463–2469.
Friedman, A and Friedman, JM. Novel Biomaterials for the Sustained Release of Nitric Oxide: Past, Present, and Future. Expert Opin Drug Deliv. 2009; 6(10): 1113-1122.
Han, G, Tar, M, Dwarakka, K, Friedman, A, Melman, A, Friedman, JM, Davies, KP. Nanoparticles as a Novel Delivery Vehicle for Therapeutics Targeting Erectile Dysfunction. J Sexu Med. 2010; 7(1 Pt 1):224-33.
Martinez, LM, Mihu, MR, Han, G, Cordero, RJB, Casadevall, A, Friedman, A, Friedman, JM, Nosanchuk, JD. Chitosan Effectively Damages Cryptococcus Neoformans Biofilms. Biomaterials 2010; 31(4): 669-79.
Zippin, J and Friedman A. An Update on Nanotechnology in Cosmetics and Sunscreens. J Drugs Dermatol. 2009; 8(10): 955-958.
Han, G, Martinez, LM, Mihu, MR, Friedman, A, Friedman, JM, Nosanchuk, J. Nitric Oxide Releasing Nanoparticles are Therapeutic for Staphylococcus aureus Abscesses in Murine Model of Infection. PLoS ONE 2009; 4(11): e7804.
Cabrales, P, Han, G, Roche C, Nacharaju, P, Friedman, A, Friedman, J. Sustained Release Nitric Oxide from Long Lived Circulation Nanoparticles. Free Rad Med. 2010; 49(4):530-8.
Englander, L and Friedman, A. Nitric Oxide Nanoparticle Technology: A Novel Antimicrobial Agent in the Context of Current Treatments for Skin and Soft Tissue Infections J Clin Aesth Dermatol. 2010; 3(6): 45-50.
Nasir, A and Friedman, A. Nanotechnology and the Nanodermatology Society. J Drugs Dermatol. 2010; 9(7): 879-882.
Cabrales, P, Han, G, Nacharaju, P, Friedman, AJ, Friedman, JM. Reversal of Hemoglobin-Induced Vasoconstriction with Sustained Release of Nitric Oxide. Am J Physiol Heart Circ Physiol. 2011; 300(1):H49-56.
Nacharaju, P, Friedman, AJ, Friedman, JM, Cabrales, P. Exogenous Nitric Oxide Prevents Collapse during Hemorrhagic Shock. Resuscitation. Published Online 2/21/11.
Friedman, A, Jacobson, M, Mann, R. Extensive Ulcerated Pigmented Nodules. J Am Acad Dermatol.2011; 64(5): 994-996.
Friedman, A, Blecher, K, Sanchez, D, Tuckman-Vernon, C, Gialanella, P, Friedman, JM, Martinez, L, Nosanchuk, J. Susceptibility of Gram Positive and Negative Bacteria to Novel Nitric Oxide-Releasing Nanoparticle Technology. Virulence. 2011; 2(3). Online
Friedman, A, Blecher, K, Schairer, D, Tuckman-Vernon, C, Nacharaju, P, Sanchez, D, Gialanelll, P, Martinez, L, Friedman, J, and Nosanchuk, J. Improved Antimicrobial Efficacy with Nitric Oxide Releasing Nanoparticle Generated S-Nitrosoglutathione. Nitric Oxide. 2011; 25: 381-386.
Schairer, D, Martinez, L, Blecher, K, Chouake, J, Nacharaju, P Gialanella, P, Friedman J, Nosanchuk, J, Friedman, A. Nitric Oxide Nanoparticles: Pre-clinical Utility as a Therapeutic for Intramuscular Abscesses. Virulence 2012; 3(1):1-6.
Blecher, K Martinez, LR, Tuckman-Vernon, C, Nacharaju, P, Schairer, D, Chouake, J, Friedman, JM, Alfieri, A, Guha, C Nosanchuk, JD, Friedman, A. Nitric oxide-releasing nanoparticles accelerate wound healing in NOD-SCID mice. Nanomedicine 2012 Mar 6. [Epub ahead of print].
Marcherla, C, Sanchez, DA, Ahmadi, M, Vellozi, EM, Friedman, AJ, Nosanchuk, JD, Martinez, LR. Nitric Oxide Releasing Nanoparticles for the Treatment of Candida albicans Burn Infections. Front. Microbio. 2012;3:193. [Epub 2012 Jun 8.]
Tuckman-Vernon, C, Maier, KE, Chouake, J, Friedman, A, Cabrales, P, Friedman, JM, Nacharaju, P. A Nanoparticle Delivery Vehicle for S-nitroso-N-acetyl cysteine: Sustained Vascular Response. Nitric Oxide. 2012 Jun 15. [Epub ahead of print]
Chouake, J, Schairer, D, Kutner, A, Sanchez, D, Makdisi, J, Blecher-Paz, K, Nacharaju, P, Tuckman-vernon, C, Gialanella, P, Friedman, JM, Nosanchuk, JD, Friedman, A. Nitrosoglutathione Generating Nitric Oxide Nanoparticles as an Improved Strategy for Combating Pseudomonas aeruginosa – Infected Wounds. J Drugs Dermatol. 2012; 11(12):1471-1477.
Friedman, AJ, Phan, J, Schairer,D, Champer, J, Qin, M , Pirouz, A, Blecher, K, Oren,A, Modlin, RL, and Kim,J. Antimicrobial and anti-inflammatory activity of chitosan-alginate nanoparticles: a novel targeted therapy for cutaneous pathogens. J Invest. Dermatol. 2013;133(5):1231-9.
Sanchez, D, Schairer, D, Tuckman-Vernon, C, Chouake, C, Kutner, A, Makdisi J, Friedman, J, Nosanchuk J, Friedman, A. Amphotericin B Releasing Nanoparticle Topical Treatment of Candida in the Setting of a Burn Wound. Nanomedicine. Published online 6/14/13.
Adler, B, Krausz, A, and Friedman A. Acinetobacter baumannii as a mutli-drug resistant emerging skin and soft tissue pathogen: Parallels to methicillin-resistant Staphylococcus aureus. JAMA Dermatolog. Published online June 18th 2014.
Krausz AE, Adler BL, Cabral V, Navati MH, Doemer J, Charafeddine R, Chandra D, Liang H, Gunther L, Clendaniel A, Harper S, Friedman JM, Nosanchuk JD, Friedman AJ. Curcumi- encapsulated nanoparticles as an innovative antimicrobial and wound healing agent. Nanomedicine. 2014 Sep 16. pii: S1549-9634(14)00527-9. doi: 10.1016/j.nano.2014.09.004. [Epub ahead of print].
Tar M, CabralesP, Navati M, Adler B, NacharajuP, FriedmanA, FriedmanJ, Davies K. Topically applied NO-releasing nanoparticles can increase intracorporal pressure and elicit spontaneous erections in a rat model of radical prostatectomy. J Sex Med. 2014;11(12):2903-14
Adler BA, Krausz AE, Tian J, Nosanchuk JD, Kirsner R, Friedman AJ. Modifiable Lifestyle Factors in Psoriasis: Screening and Counseling Practices Among Dermatologists and Dermatology Residents in Academic Institutions. J Am Acad Dermatol. 2014; 71(5): 1028-1029.
Landriscina A, Musaev T, Friedman A. A Surprising Case of Mycobacterium avium Complex Skin Infection in an Immunocompetent Patient. J Drugs Dermatol. 2014;13(12):1491-149.
Mordorski B, Pelgrift R, Krausz A, Adler B, Batista A, Liang H, Gunther L, Clendaniel A, Harper S, Friedman JM, Nosanchuk JD, Nacharaju P, Friedman AJ. S-nitrosocaptopril Nanoparticles as Nitric Oxide-Liberating and Transnitrosylating Anti-infective Technology. Nanomedicine. 2015; 11(2): 283-291.
Greisman L,Nguyen TM,Mann RE,Baganizi M, Jacobson M, Paccione GA,Friedman AJ, Lipoff JB.Feasibility and cost of a medical student proxy-based mobile teledermatology consult service with Kisoro, Uganda and Lago Atitlán, Guatemala. Int J Dermatol. 2014 Dec 29.
Nguyen TA,Patel PS, Viola KV, Friedman AJ. Pseudofolliculitis Barbae in Females: A Clinical Perspective. Br J Dermatol. 2014 Dec 30.
Rosen J, Landriscina A, Kutner A, Adler B, Krauz A, Nosanchuk D, Friedman A. Silver Sulfadiazine Retards Wound Healing in Mice via Alterations in Cytokine Expression. J Invest. Dermatol. Published online January 27th 2015.
Charafeddine RA, Makdisi J, Schairer D, O'Rourke BP, Diaz-Valencia JD, Chouake J, Kutner A, Krausz A, Adler B, Nacharaju P, Liang H, Mukherjee S, Friedman JM, Friedman A, Nosanchuk JD, Sharp DJ. Fidgetin-Like 2: A Microtubule-Based Regulator of WoundHealing. J Invest Dermatol. 2015 Mar 10. doi: 10.1038/jid.2015.94. [Epub ahead of print]
Adler B, Kraus AE, Landriscina A, Musaev T, Nosanchuk JD, Friedman AJ. Biafine topical emulsion accelerates excisional and burn wound healing in mice. Arch Dermatol Res. 2015 Mar 21. [Epub ahead of print]
Baltazar LM, Karusz AE, Souza AC, Adler B, Landriscina A, Musaev T, Nosanchuk JD, Friedman AJ. Trichophyton rubrum is inhibited by free and nanoparticle encapsulated curcumin by induction of nitrosative stress after photodynamic activation. PLoS ONE 10(3): e0120179. doi:10.1371/journal. pone.0120179
Akhavan A, Murphy-Cotorian B, and Friedman A. Pediatric Dermatology Training During Residency: A Survey of the 2014 Graduating Residents. Pediatr Dermatol. 2015 Mar 26. doi: 10.1111/pde.12565. [Epub ahead of print].
Doerner J, Wen J, Xia Y, Blecher Paz K, Schairer D, Wu L, Chalmers SA, Izmirly P,Michaelson JS, Burkly LC, Friedman A, and Putterman C.TWEAK/Fn14 Signaling Involvement in the Pathogenesis of Cutaneous Disease in the MRL/lpr Model of Spontaneous Lupus J Invest Dermatol doi:10.1038/jid.2015.124; accepted article preview online March 31, 2015
Rosen J, Landriscina A, Adler B, Krausz A,Doerner J, Navati M, Gravekamp C, Nosanchuk J, Friedman A.Characterization and Assessment of Nanoencapsulated Sanguinarine Chloride as a Potential Treatment for Melanoma. J Drugs Dermatol. 2015;14(5):453-458.
Nanotechnology in Dermatology. Ed. Nasir, Friedman, Wang. Springer Publishing LLC. 2013, XVII, 291 p.
Nanomedicine in Drug Delivery. Ed. Kumar, Mansour, Friedman and Blough. CRC Publishing LLC. 2013, 450 p.
Material in this section is provided by individual faculty members who are solely responsible for its accuracy and content.