Pilot & Feasability Awards

Small molecule inhibition of ganglioside synthesis as potential therapy for free sialic acid storage disease.

Investigator: Kostantin Dobrenis, Ph.D.
Assistant Professor, Dominick P. Purpura Department of Neuroscience

Molecular dysfunction of cytoplasmic dynein in brain developmental diseases

Investigator: Arne Gennerich, Ph.D.
Associate Professor, Department of Anatomy & Structural Biology

Modeling CACNA1A-associated intellectual disability using human cerebellar neurons derived from induced pluripotent stem cells

Investigator: Herbert M. Lachman M.D., Ph.D.
Professor, Department of Psychiatry and Behavioral Sciences
Associate Professor, Dominick P. Purpura Department of Neuroscience
Associate Professor, Department of Genetics
Investigator: Deyou Zheng, Ph.D.
Professor, Dominick P. Purpura Department of Neuroscience
Professor, Department of Genetics
Professor, The Saul R. Korey Department of Neurology

DYNC1H1 mutant in zebrafish-to model a human phenotype

Investigator: Bridget Shafit-Zagardo, Ph.D.
Professor, Department of Pathology
Investigator:  Teresa Bowman, Ph.D.
Professor, Department of Developmental & Molecular Biology

Impact of COL4A1 mutations on function and remodeling of the neurovascular unit

Investigator: David Spray, Ph.D.
Professor, Dominick P. Purpura Department of Neuroscience
Professor, Department of Medicine (Cardiology)

The role of Fragile X mental retardation protein in presynaptic protein synthesis and plasticity

Investigator: Pablo Castillo, M.D., Ph.D.
Professor, Dominick P. Purpura Department of Neuroscience
Professor, Department of Psychiatry Behavioral Sciences
Harold and Muriel Block Chair in Neuroscience

Crk and Crkl mutations as causes for epilepsy in IDD

Investigator: Aristea Galanapoulou M.D., Ph.D.
Professor, The Saul R. Korey Department of Neurology (Child Neurology)
Professor, Dominick P. Purpura Department of Neuroscience
Investigator: Jean M. Hebert Ph.D.
Professor, Dominick P. Purpura Department of Neuroscience
Professor, Department of Genetics

Modeling the neuropsychiatric manifestations of Lowe Syndrome using induced pluripotent stem cells

Investigator: Herbert M. Lachman M.D., Ph.D.
Professor, Department of Psychiatry and Behavioral Sciences
Associate Professor, Dominick P. Purpura Department of Neuroscience
Associate Professor, Department of Genetics
Investigator: Deyou Zheng, Ph.D.
Professor, Dominick P. Purpura Department of Neuroscience
Professor, Department of Genetics
Professor, The Saul R. Korey Department of Neurology

Studies on Pol III-Associated Leukodystophy

Investigator: Ian M. Willis, Ph.D.
Professor, Department of Biochemistry
Professor, Department of Systems & Computational Biology

Converging mechanisms in Autism Spectrum Disorder

Investigator: Bryen Jordan, Ph.D.
Associate Professor, Dominick P. Purpura Department of Neuroscience
Associate Professor, Department of Psychiatry Behavioral Sciences

Binding studies of neural cell adhesion proteins

Investigator: Steve Almo, Ph.D.
Chair, Department of Biochemistry
Wollowick Family Foundation Chair in Multiple Sclerosis & Immunology
Director, Einstein Macromolecular Therapeutics Development Facility
Professor, Department of Biochemistry
Professor, Department of Physiology & Biophysics

Investigator: Scott Emmons, Ph.D.
Siegfried Ullmann Chair, Molecular Genetics
Professor, Dominick P. Purpura Department of Neuroscience
Professor, Department of Genetics

Exploring nAChR Function in Fragile X Syndrome

Investigator: Anna Francesconi, Ph.D.
Assistant Professor, Developmental Medicine

Converging mechanisms in Autism Spectrum Disorder

Investigator: Bryen Jordan, Ph.D.
Associate Professor, Dominick P. Purpura Department of Neuroscience
Associate Professor, Department of Psychiatry Behavioral Sciences

Whole exome sequence analysis of ID in patients with 22q11.2DS

Investigator: Bernice Morrow, Ph.D.
Sidney L. and Miriam K. Olson Chair in Cardiology
Director, Division of Translational Genetics, Department of Genetics
Professor, Department of Genetics
Professor, Department of Obstetrics & Gynecology and Women's Health
Professor, Department of Pediatrics (Pediatric Cardiology)

Cerebellar hypoplasia and saccadic adaptation in Autism Spectrum Disorder

Investigator: Lars Ross, Ph.D.
Assistant Professor, Developmental Medicine

Autophagy as a new therapeutic target for cognitive defects in Fragile X Syndrome

Investigator: Suzanne Zukin, Ph.D.
Professor, Dominick P. Purpura Department of Neuroscience
Director, Neuropsychopharmacology Center
F.M. Kirby Chair in Neural Repair and Protection

The neurophysiological underpinnings of sensory-motor dysfunctions in autism spectrum disorder

Investigator: Pierfilippo De Sanctis, Ph.D.
Research Assistant Professor, Department of Pediatrics (Developmental Medicine)
Research Assistant Professor, The Saul Korey Department of Neurology

MECP2 and 5-hydroxymethylcytosine in epigenetic regulation of neuronal gene expression and etiology of Rett Syndrome

Investigator: Meelad Dawlaty, Ph.D.
Assistant Professor, Department of Genetics

Identification of novel pathogenic pathways and therapeutic targets in CNS of lysosomal storage disease

Investigator: Kostantin Dobrenis, Ph.D.
Assistant Professor, Dominick P. Purpura Department of Neuroscience

Protection against hearing loss with Cyclodextrin treatment of Niemann-Pick Type C Disease

Investigator: Vytautas Verselis, Ph.D.
Professor, Dominick P. Purpura Department of Neuroscience

Uncovering the molecular link between CHD8 and ASD

Investigator: Deyou Zheng, Ph.D.
Associate Professor, Dominick P. Purpura Department of Neuroscience
Associate Professor, Department of Genetics
Associate Professor, The Saul Korey Department of Neurology

Learning during an early sensitive period in chickens

Investigator:
Jose Pena, Ph.D.
Professor, Dominick P. Purpura Department of Neuroscience

Elucidation of the mechanism of trinucleotide repeat instability in patient cells

Investigator:
Jeannine Gerhardt, Ph.D.
Instructor, Department of Cell Biology

Primary microglial dysfunction in a subset of ASD

Investigator:
Herb Lachman, M.D.
Professor, Department of Psychiatry and Behavioral Sciences
Professor, Department of Medicine (Hematology)
Associate Professor, Dominick P. Purpura Department of Neuroscience
Associate Professor, Department of Genetics

Is increased surface CCR2 on mature monocytes from perinatally HIV infected and perinatally HIV exposed children a biomarker of neurocognitive impairment?

Investigators:
Joan Berman, Ph.D.
Professor, Department of Pathology
Professor, Department of Microbiology & Immunology
Professor, Department of Microbiology & Immunology
Senior Academic Advisor to the Graduate Division

Kami Kim, M.D.
Professor, Department of Medicine (Infectious Diseases)
Professor, Department of Microbiology & Immunology
Professor, Department of Pathology

Biomarkers to predict neurodevelopmental outcomes in very preterm infants

Investigators:
Mamta Fuloria, M.B., B.S.
Assistant Professor, Department of Pediatrics (Neonatology)

Maureen J. Charon, Ph.D.
Professor, Department of Biochemistry
Professor, Department of Obstetrics and Gynecology and Woman’s Health
Professor, Department of Medicine

William A. Gomes, M.D., Ph.D.
Assistant Professor, Department of Radiology (Neuroradiology)

Genetics causes of intellectual disability in 22q11DS patients

Investigator: Tingwei Guo, Ph.D.
Research Assistant Professor, Department of Genetics

Dynamic live cell single molecule imaging of MeCP2 mutants linked to neurological disorders

Investigator:
Robert Coleman, Ph.D.
Assistant Professor, Department of Anatomy and Structural Biology

MeCP2, mRNA, gap junctions and glia

Investigators:
David C. Spray, Ph.D.
Professor of Neuroscience and Medicine

Randy Stout, Ph.D.
Research Fellow

Establishing an in vivo high-density electrophysiological methodology to interrogate circuit-level functional connectivity in genetic mouse models of autism

Investigators:
John Foxe, Ph.D.
Professor, Department of Pediatrics
Professor, Dominick P. Purpura Department of Neuroscience
Noboru Hiroi, Ph.D.
Professor, Department of Psychiatry and Behavioral Sciences
Professor, Dominick P. Purpura Department of Neuroscience
Associate Professor, Department of Genetics

Impaired inter-hemispheric communication, information processing differences, executive function deficits, and network communication in ASD

Investigator: Sophie Molholm, Ph.D.
Associate Professor, Dominick P. Purpura Department of Neuroscience
Associate Professor, Department of Pediatrics

Adverse Childhood Experiences (ACEs)

Investigator: Anne Murphy, Ph.D.
Assistant Professor, Department of Pediatrics (Child Development)

Characterization of Slc9a6 and Slc9a9 KO mice and their relationship to neurogenetic disease

Investigator: Steven Walkley, D.V.M., Ph.D.
Professor, Dominick P. Purpura Department of Neuroscience
Professor, Department of Pathology
Professor, The Saul R. Korey Department of Neurology
Director, Rose F. Kennedy Intellectual and Developmental Disabilities Research Center

The mammalian target of rapamycin complex 2 (mTORC2) as a critical regulator of synaptic defects in Fragile X Syndrome

Investigator: Suzanne Zukin, Ph.D.
Professor, Dominick P. Purpura Department of Neuroscience
Director, Neuropsychopharmacology Center
F.M. Kirby Chair in Neural Repair and Protection

Functional Brain Mechanisms of Inattention in Children with ASD and ADHD

Investigator: Xiaobo Li, Ph.D.
Assistant Professor, Department of Radiology
Assistant Professor, Dominick P Purpura Department of Neuroscience
Assistant Professor, Department of Psychiatry and Behavioral Sciences

Epigenetic regulation by MeCP2 and its role in neuronal diseases

Investigator: Michael Brenowitz, Ph.D.
Professor, Department of Biochemistry

Synaptic connectivity using three mouse models of ASD

Investigator: Pablo Castillo, Ph.D.
Professor, Dominick P. Purpura Department of Neuroscience

Automated quantification of motor stereotypies in children with Autism Spectrum Disorders

Investigator: Sylvie Goldman, Ph.D.
Instructor, The Saul R. Korey Department of Neurology and Department of Pediatrics

Exploring a role for AIDA-1 in Schizophrenia and Autism Spectrum Disorders

Investigator: Bryen Jordan, Ph.D.
Assistant Professor, Dominick P. Purpura Department of Neuroscience
Assistant Professor, Department of Psychiatry and Behavioral Sciences

The TWEAK/Fn14 pathway in the pathogenesis and treatment of neuropsychiatric systemic lupus erythematosus (NPSLE)

Investigator: Chaim Putterman, M.D.
Professor, Department of Medicine
Professor, Department of Microbiology & Immunology

Intellectual disability caused by mutations in KDM5C

Investigator: Julie Secombe, Ph.D.
Assistant Professor, Department of Genetics

Saturday, March 5th, 2012

Dr. Catherine Lord
From 2 to 22: As the number of preschool children identified with Autism Spectrum Disorder (ASD) increases each year, so too will the number of children with ASD moving

Monday, December 17, 2012

Brett Abrahams, Ph.D.
Assistant Professor, Department of Genetics
Albert Einstein College of Medicine
Combined Clinical and Molecular Genetics Conference
Topic: Structural variation at 15q11.2

Monday, December 10, 2012

Tong Sheng
Doctoral Candidate
Brain and Creativity Institute
Neuroscience Graduate Program
University of Southern California
Task-specific network-level representations of human vocal emotions

Thursday, December 6, 2012

First Annual Isabelle Rapin Conference on Communicable Disorders
WILLIAMS SYNDROME WORKSHOP AND ROUNDTABLE

Tuesday, December 4, 2012

David J. Lewkowicz, Ph.D.
Professor
Department of Psychology and Center for Complex Systems & Brain Sciences
Florida Atlantic University
The Critical Role of Experience in the Acquisition of Knowledge in Human Infants

Monday, December 3, 2012

Yuliya Yoncheva, Ph.D.
Postdoctoral Fellow
Department of Psychology and Human Development
Peabody College, Vanderbilt University
Brain correlates of selective attention to language: implications for reading acquisition

Wednesday, November 21, 2012

Ian Robertson, Ph.D.
Visiting Professor of Neurology at Columbia University, New York
Professor of Psychology at Trinity College Dublin, Ireland
Why education and mental stimulation protect the brain: The role of noradrenaline in cognitive reserve

Monday, November 19, 2012

Bernice Morrow, Ph.D.
Professor, Departments of Genetics, Obstetrics & Gynecology and Women's Health, and Pediatrics
Director, Division of Translational Genetics, Department of Genetics
Sidney L. and Miriam K. Olson Chair in Cardiology
Albert Einstein College of Medicine
Susan Klugman, M.D.
Clinical Genetics, Obstetrics & Gynecology
Montefiore Medical Center
Associate Professor of Clinical Obstetrics & Gynecology and Women's Health
Albert Einstein College of Medicine
Combined Clinical and Molecular Genetics Conference
Topic: Highlights from the 2012 American Society of Human Genetics Meeting

Saturday, November 17, 2012

B.R.A.I.N. Kids!

Thursday, November 1, 2012

Aristea Galanopoulou, M.D., Ph.D.
Associate Professor, Department of Neurology
Associate Professor, Department of Neuroscience
Albert Einstein College of Medicine
Modeling new therapies for infantile spasms, lessons from animal models

Monday, October 15, 2012

Bernice Morrow, Ph.D.
Professor, Departments of Genetics, Obstetrics & Gynecology and Women's Health, and Pediatrics
Director, Division of Translational Genetics, Department of Genetics
Sidney L. and Miriam K. Olson Chair in Cardiology
Albert Einstein College of Medicine
Combined Clinical and Molecular Genetics Conference
Topic: 22q11.2 Deletion Syndrome

Thursday, October 4, 2012

Brett Abrahams, Ph.D.
Assistant Professor, Department of Genetics
Albert Einstein College of Medicine
Integrative Approaches to the Autism Spectrum Disorder: from molecules to behaviors

Wednesday, September 26, 2012

Christopher Brett, Ph.D.
Assistant Professor and Canada Research Chair
Biology Department, Concordia University
Christianson syndrome, ADHD and NHEs: How sodium/hydrogen exchangers control neuronal endocytosis and their relationship to disease

Monday, September 24, 2012

Aleksandra Djukic, M.D., Ph.D.
Associate Professor of Clinical Neurology and Pediatrics
Director of the Center for Rett Syndrome
Albert Einstein College of Medicine and Montefiore Medical Center
Combined Clinical and Molecular Genetics Conference
Topic: Rett Syndrome

Wednesday, July 18, 2012

Daniel Senkowski, Ph.D.
Professor of Clinical Neuropsychology, Multisensory Integration Research Group
Department of Psychiatry and Psychotherapy, Charité, University Medicine Berlin, Germany
Crossmodal biasing of pain

Monday, July 16, 2012

Curtis Deutsch, Ph.D.
Associate Professor, Department of Psychiatry, UMMS
Director, Craniofacial Research Program and Psychobiology Program, Eunice Kennedy Shriver Center UMMS
Mclean Hospital, Harvard Medical School
Craniofacial and brain dysmorphology in autism and schizophrenia

Friday, July 6, 2012

Manuel Garcia-Garcia, Ph.D.
Postdoctoral Fellow, Phyllis Green and Randolph Cowen Institute for Pediatric Research, NYU Child Study Center, New York
Intra-individual stability of resting-state functional networks: a new reliable tool shows functional segregation of the basal ganglia in ADHD

Monday, May 21, 2012

Rick Kaskel, M.D., Ph.D.
Chief of the Division of Nephrology in Pediatrics at Albert Einstein College of Medicine
Galina Nesterova, M.D.
National Human Genome Research Institute (NHGRI)
Combined Clinical and Molecular Genetics Conference
Topic: Cystinosis, a lysosomal storage disease

Thursday, May 17, 2012

Dean Salisbury, Ph.D.
Director, Cognitive Neuroscience Laboratory, McLean Hospital
Associate Professor, Department of Psychiatry, Harvard Medical School
Neurophysiology of sensory memory: A potential tool for early diagnosis of schizophrenia

Wednesday, May 9, 2012

John Foxe, Ph.D.
Professor of Pediatrics and Neuroscience, and Director of CERC at Albert Einstein College of Medicine (AECOM)
Sophie Molholm, Ph.D.
Associate Professor of Pediatrics and Neuroscience, and Muriel and Harold Block Faculty Scholar in Mental Illness at AECOM
Multisensory Processing in Children with Autism and Sensory Processing Disorder

Tuesday, April 24, 2012

Clayton Curtis, Ph.D.
Associate Professor of Psychology, Department of Psychology and Center for Neural Science, New York University
Topographical Maps of Prioritized Space in Frontal and Parietal Cortex

Tuesday, April 10, 2012

Edmund Lalor, Ph.D.
Assistant Professor, School of Engineering & Institute of Neuroscience, Trinity College Dublin, Ireland
Towards Improved Specificity and Flexibility in EEG-based Sensory Research: Cognitive and Clinical Applications

Friday, April 6, 2012

John Jeka, Ph.D.
Professor, Department of Kinesiology, University of Maryland
Multisensory Fusion and Human Balance Control

Tuesday, March 27, 2012

Brian Keane, Ph.D.
Research Associate at UMDNJ - Robert Wood Johnson Medical School and Rutgers University Center for Cognitive Science
Perceptual Organization Deficits in Schizophrenia: Why Do They Happen and Why Should We Care?

Monday, March 5, 2012

Catherine Lord, Ph.D.
Director of the Center for Autism and the Developing Brain (CADB), a subsidiary of Weill Cornell Medical College and New York Presbyterian Hospital
Longitudinal Studies in the Autism Spectrum Disorders: From 2 to 22

Wednesday, February 29, 2012

Rare People and Rare Talents on a Rare Day
A Special Concert in Celebration of Rare Disease Day