Stable Isotope & Metabolomics Core

About Us

Services and Objectives

  • In vivo stable isotope substrate flux assays to determine rates of protein synthesis, lipogenesis and peripheral glucose disposal.
  • Assessments of plasma and tissue metabolite profiles for diagnosis/characterization of physiological and pathophysiological states. These include key metabolites in the glycolytic, gluconeogenic, pentose phosphate, and tricarboxylic (TCA) cycle pathways, fatty acid oxidation and complex lipids.
  • In vitro assessments of glycolysis (extracellular acidification rates) and mitochondrial oxygen consumption (mitochondrial respiration) in tissue explants, primary isolated and tissue culture cells using Seahorse Biosciences Flux Analyzers.

Access the Services 

 
 
 

Contacts

Director
Irwin Kurland, M.D.
718.374.1091 
irwin.kurland@einstein.yu.edu  
Mass Spectrometer Operations
Hardik Shah
718.678.1180
hardik.shah@einstein.yu.edu  
Seahorse Operations
Xueliang Du, Ph.D.
xueliang.du@einstien.yu.edu  
 
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