The Einstein shRNA Core Facility is a state-of-the-art RNAi laboratory dedicated to providing researchers with access to reagents and services that enable loss-of-function studies at scales ranging from individual genes to genome scale. We provide RNAi reagents, shRNA-based screening services, and RNAi expertise to researchers at:
Albert Einstein College of Medicine, Montefiore Medical Center, and Yeshiva University
In addition, we offer services to members of the New York Structural Biology Center Consortium:
Columbia University; New York University; Mt. Sinai School of Medicine; Rockefeller University; Memorial Sloan-Kettering Cancer Center; State University of New York; City University of New York; Weill Cornell Medical Center; and Wadsworth Center, New York State Department of Health
The Facility houses several genome-wide shRNA and ORF libraries, from which we provide individual shRNA and ORF clones, shRNA sets for arrayed screens, and shRNA pools for selection-based screening. We are affiliated with the Albert Einstein Cancer Center.
As of August 1, 2013, the Dean's Office will subsidize 20% of the cost for Einstein investigators of obtaining shRNA- or ORF-expressing lentivirus, either as viral supernatant or concentrated viral stock, generating stable shRNA-expressing cell lines, and performing genomics screens using custom arrayed libraries.
The shRNA Core Facility now offers High-Content Screening services on the Operetta system from PerkinElmer. The instrument is available for individual plates for an hourly charge, or as part of RNAi screening projects. Contact us at shRNA@einstein.yu.edu for details.