Chemical Synthesis Core Facility

Ligands for CuAAC

 

Uses

BTTP is designed for proteomics applications and for labeling intracellular proteins in bacteria. BTTPS and BTTAA are for live cell surface labeling.The ligands are available from our core facility for a small fee.  

Purchasing Ligands

The Chemical Synthesis Core uses iLab to accept orders and to bill. To order ligands from the facility, please either log-in with your existing iLab account or sign up for an account on our iLab page.

Further reading

Biocompatible copper(I) catalysts for in vivo imaging of glycans. Soriano del Amo, D.; Wang, W.; Jiang, H.; Besanseney, C.; Yan, A, C.; Levy, M.; Liu, Y.; Marlow, F. Wu, P. J. Am. Chem. Soc. 2010, 132, 16893.

Increasing the Efficacy of Bioorthogonal Click Reactions for Bioconjugation: A Comparative Study. Besanceney, C.; Jiang, H.; Zheng, T.; Feng, Lei; Soriano Del Amo, D.; Klivansky, L.; Liu, Y.; Marlow, F.; Wu, P. Angew. Chem. Int. Ed. 2011, 50, 8051.

Sulfated ligands for the Copper(I)-catalyzed Azide-Alkyne Cycloaddition. Wang, W.; Hong, S.; Tran, A.; Jiang, H.; Triano, R.; Liu, Y. Chen, X.; Wu, P. Chem. Asian J. The “Click Chemistry 10 Years” Special Issue. 2011, 10, 2796.

Biocompatible Click Chemistry Enabled Labeling of Cytosolic Proteins and Compartment-specific pH Indicators. Yang, M.; Jalloh, A.; Wei, W. Zhao, J.*; Wu. P*; Chen, P.R.* Nature Comm. 2014, 5, Article number: 4981; doi:10.1038/ncomms5981 (*co- corresponding authors).

Monitoring Dynamic Glycosylation in Vivo Using Supersensitive Click Chemistry. Jiang, H.; Zheng, T.; Lopez-Aguilar, A.; Feng, L.; Kopp, F.; Marlow, F. and Wu, P. Bioconjugate Chem. 2014, 25, 698−706.

Contact Us

Albert Einstein College of Medicine
Gruss (MRRC) Room 314A

1300 Morris Park Ave
Bronx N.Y. 10461

E-mail: john.blanchard@einstein.yu.edu
Phone: 718.430.3096

iLab Solutions

Click here to log in