Postdoctoral Studies

Postdoctoral Program

Job Title:

Postdoctoral Position Available in Microbiome Research: Host-Microbe Interactions, Microbial Genetics, Metagenomics and Metabolomics

Job Description:

The Mani Laboratory, housed in the Chanin Building, at the Departments of Medicine, Genetics and Pharmacology and The Cancer Institute and Einstein-Mount Sinai Diabetes Research Center of The Albert Einstein College of Medicine, INC, has an open position for a highly motivated postdoctoral fellow to be part of an expanding research program on novel aspects of the mammalian microbiome.

Laboratory Research Focus and Expertise:  The Laboratory is focused on the study of orphan nuclear receptors, specifically the Pregnane X Receptor (PXR), that recognize xenobiotics (and endobiotics) as ligands and their effects on mammalian physiology and pathophysiology.  Recently, we have shown that microbial metabolites can serve as ligands for such receptors (Immunity, 2014).  In more recent work, in the study of these microbial ligands, we devised a biofilm assay that allowed for identification of new and novel bacterial species/strains from the enteric microbiota.  The goal now is to study all aspects of the importance of these species to host physiology and pathophysiology (inflammation, cancer).  These studies will include delving into the mechanisms of host-microbe (and microbe-host) interactions.  Related research can expand to study of the mechanisms of bacterial biofilms using both genetic, biochemical and biophysical approaches.

SEE:  http://www.einstein.yu.edu/faculty/5615/sridhar-mani/

Postdoctoral Expertise Required:

1. Recent doctoral degree or equivalent (e.g., MD, MD/PhD, or PhD) and/or early postdoctoral training exposure.
2. First author publication record from PhD.
3. Emphasis placed on new methods development and analytical/reasoning skills.
4. Prior experience in microbiome research and mouse work and/or metagenomics is preferred but not absolutely essential.

Please email your CV and cover letter focusing on your interests and goals, along with contact information (and/or letters) from three referees to:  sridhar.mani@einstein.yu.edu or smani855@gmail.com


The Albert Einstein College of Medicine is an equal opportunity employer committed to workforce diversity.

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