May 26, 2015—(BRONX, NY)— An international team including scientists from Albert Einstein College of Medicine of Yeshiva University and the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) has identified the molecular “lock” that the deadly Ebola virus must pick to gain entry to cells. The findings, made in ...read more
Manipulating Mycobacteria—Bacteria can exchange genetic information amongst each other by transferring plasmids—small, circular DNA that are different from chromosomal DNA. Scientists capitalize on this natural process by constructing artificial plasmids to experimentally manipulate bacteria, helping them to understand the genetic basis of important traits. Since the bacterium that causes TB—Mycobacterium tuberculosis—can be lethal, labs often use the closely related M. smegmatis... read more
Diabetes and Obesity — Obese people are at increased risk for developing insulin resistance and type 2 diabetes. Chronic inflammation in abdominal fat (known as adipose tissue) can lead to insulin resistance. A study by Dr. Jeffrey Pessin in the November 2014 issue of Cell Reports offers insight into how inflammation caused by a high-fat diet is regulated within adipose... read more
Breast Cancer Risk — Obesity is a well-established risk factor for breast cancer in postmenopausal women. Prior studies by Drs. Howard Strickler and Marc Gunter and colleagues, suggested that insulin might help explain this breast cancer – obesity relationship. But whether obese women with normal insulin levels (so called “healthy-obese”) also had high breast cancer risk was unknown. In a... read more
Every day, Dr. Jill Crandall confronts diabetes and its harmful complications, which include heart, kidney, eye and foot damage. Her goal: to prevent the disease and its serious, life-changing effects.
Dr. Pessin directs Einstein’s Diabetes Research Center, one of only sixteen NIH-funded diabetes centers of its kind in the country. ...read more