August 19, 2015—(BRONX, NY)—If a pregnant woman with high blood pressure and no history of headache suddenly develops a headache that quickly worsens, she could be at risk for pregnancy complications, including preeclampsia, which put both the mother and fetus at risk. These and other findings from a new study ...read more
Hormonal Regulation of Obesity—Leptin, the so-called satiety hormone, is made by fat cells and helps regulate energy balance by inhibiting hunger. One brain area particularly responsive to leptin is the arcuate nucleus of the hypothalamus (ARC). The ARC contains proopiomelanocortin (POMC) neurons that are crucial for regulating both energy and glucose balance. Leptin is known to trigger POMC neuron activity by... read more
Targeting Tuberculosis — In a recent issue of the Proceeding of the National Academy of Sciences, Einstein researchers describe a new strategy for killing Myobacterium tuberculosis (Mtb), the bacterial species that causes TB. Drs. Michael Berney, Linda Berney-Meyerand William Jacobs found that MTb’s ability to successfully infect hosts and survive in their tissues depends on synthesizing the... read more
New Aging Targets—By digesting and recycling worn-out proteins and other molecules, chaperone-mediated autophagy (CMA) is crucial for maintaining cellular health. Impaired CMA is associated with aging and with neurodegenerative diseases, including Parkinson’s and Alzheimer’s. In a study published in the June 25, 2015 online issue of Molecular Cell, Dr. Ana Maria Cuervo and colleagues examined how CMA activity is... read more
Dr. John Blanchard’s scientific contributions have earned him the Repligen Award in Chemistry of Biological Processes from the American Chemical Society’s Division of Biological Chemistry.
A noted authority on headaches and migraine, Dr. Lipton is director of the Montefiore Headache Center, recognized internationally for its ...read more