The Translational Neuroimaging Laboratory – Michael L. Lipton, M.D., Ph.D.

Bios

Faculty

Roman Fleysher, PhD  

In clinical MRI time is at premium. My research focuses on development and implementation of data acquisition strategies for efficient measurements in MRI.

 
 

Namhee Kim, PhD 

Dr. Kim received her PhD in Biostatistics from the Ohio State University (USA) in 2010. She joined the Department of Radiology at Albert Einstein College of Medicine in 2010. Her current research is focused on the development of statistical methodologies with medical image data, e.g. functional magnetic resonance image, diffusion tensor image. Her statistical expertise includes Bayesian data analysis, time-series models, dynamic linear and nonlinear models, small area estimation, and various mixed effects models.

 
 

Michael L. Lipton, MD, PhD 

I straddle the practice of clinical medicine, research and education toward improving human brain health through the effective use of modern brain imaging technology. While magnetic resonance imaging (MRI) is my central tool, I define brain imaging broadly, to include all methods that facilitate accurate depiction of brain structure and function as well as their interface. As a neuroradiologist, I advocate looking beyond the visual percept in making an assessment of diagnostic images, using quantitative approaches to maximize diagnostic yield, improve accuracy and minimize risk, including the risk of misdiagnosis. These approaches are developed and validated in the laboratory, then applied in clinical research populations and, ultimately, real patients. I push students at all levels to understand the technology they wield and use it intelligently for the ultimate betterment of patients.

 
 

Asif K. Suri, MD, PhD 

My research focus has been in diffusion tensor imaging (DTI), developing methods to allow for a more accuracy representation of diffusion measures within the brain, with applications to specific disease states. Specifically, work has involved improving the accuracy in the identification of diffusion abnormalities in the brain through changes in the brain registration process.

I have completed graduate work at Rutgers University in biophysical chemistry/molecular biophysics involved developing methods to improve the quality of 3D structures of protein molecules produced using NMR data. Postdoctoral work in structural biology at Memorial Sloan-Kettering Cancer Center involved elucidation of the 3D structures of DNA/carcinogen and RNA/antibiotic complexes from NMR data. After completing medical school at Cornell and a residency at Downstate, I completed a clinical Neuroradiology fellowship at Montefiore Medical Center, receiving a CAQ in neuroradiology.

 
 

Mark E. Wagshul, PhD 

My primary interest is in using imaging technology for elucidating the pathophysiology of hydrocephalus. Hydrocephalus, a disease which is most common in newborns and young children, although it is also one of the causes of dementia in the elderly, is characterized by an increased accumulation of fluid in the brain. It is associated with brain development, cognitive and motor function delays and deficits. In collaboration with researchers at the University of Utah, we are working on characterizing the role of brain pulsations in the development and progression of ventricular dilation in hydrocephalus. We use MRI and multi-photon confocal microscopy to image blood and cerebrospinal fluid flow in an animal, and are now working with the Einstein Behavioral Core to evaluate potential biomarkers of disease severity and of recovery following shunting of the fluid from the brain. The work obviously has important clinical application, and we are working on improved imaging techniques for quantifying pulsatile fluid flow in the brain and its relationship to hydrocephalus and recovery following shunt surgery.

I am also interested in a technique called MR-spectroscopy (MRS), in which MRI can be used to quantify concentrations of common metabolites in the brain. We use MRS to understand white and grey matter degradation in multiple sclerosis. Using techniques based on principle component analysis and metabolomic analysis, we are able detect changes in MS lesions as well as in "normal-appearing" white matter in the MS brain. We also use diffusion tensor imaging, a technique which can detect changes in myelin microstructure, as well as volumetric analyses to understand the effect of hippocampal atrophy, for example, on cognitive function. This work is ongoing in collaboration with investigators are Stony Brook University.

Finally, I am interested in MRI pulse sequence development, i.e. manipulating the MRI machine to extract new types of information from MRI images.

 
 
 
 

Staff

Kyle FriedmanKyle Friedman, MA 

Kyle graduated from the University of Delaware in May 2015 with a combined Master's and Bachelors Degree in Cognitive Science, as well as a Bachelor's in Psychology. He is currently one of three research coordinators in Dr. Lipton's lab, assisting in data collection and analysis for various MRI studies (primarily the Soccer Study, which investigates potential implications from heading the ball). Prior experience includes working in Dr. Tim Vickery's Vision & Decision Making lab, as well as Dr. Chad Forbes' Social Neuroscience lab - both at the University of Delaware. He plans to apply to Neuroscience or Psychology PhD programs in the future, hopefully performing research in the field of Chronic Traumatic Encephalopathy (CTE).

   

   

   

Chloe IfrahChloe Ifrah, BA  

Chloe Ifrah graduated from Washington University in Saint Louis in May 2015 with college honors and a bachelor’s degree in Psychology. She is currently a clinical research coordinator for Dr. Michael Lipton, assisting with the organization and logistics of his studies, as well as processing analyzing data for his MRI/DTI research studies. She is very interested in the correlation between brain function and cognitive and psychological dysfunction. Prior to working at Einstein, Chloe was a research assistant at WashU in the Behavioral Research and Imaging Neurogenetics lab for 2.5 years. She plans to apply to clinical psychology doctorate programs in the future.

   

   

Naomi WakschlagNaomi Wakschlag, BA    

Naomi graduated summa cum laude from Stern College for Women in May 2015, with a bachelor’s degree in Psychology. She is currently a research assistant in Dr. Michael Lipton’s lab, and helps facilitate and process data for the MRI studies. Prior to working in Dr. Lipton’s lab, Naomi worked with Dr. Daniel Pine at the National Institute of Mental Health, Dr. Leah Dougherty at the University of Maryland, and Dr. Eva Gilboa-Schechtman at Bar-Ilan University. Naomi also conducted her own research at Stern College under the supervision of Dr. Terry DiLorenzo. In the future, Naomi hopes to attend a PhD program in Psychology.

 
 

 

  

 
 
 
 

Students, Residents, & Fellows

 

Eva Catenaccio, BA 

Eva Catenaccio is a medical student at Einstein. She is spending a year in the lab doing research on differential gender outcomes in mild traumatic brain injury. She is interested in pursuing a career in neurology.

 
 

wouter hoogenboomWouter Hoogenboom, MA  

Wouter is a PhD student in the biomedical science and clinical research program at Einstein and is interested in using advanced neuroimaging techniques and cognitive tools to study sports-related brain injury. Wouter’s educational background is in neuropsychology and he previously used neuroimaging to study brain abnormalities in a variety of clinical conditions, including depression, schizophrenia, diabetes, and traumatic brain injury. Wouter enjoys off-site research, as well as on-site interaction with patients. His goal is to further develop a career in clinical and translational research contributing to a better understanding, treatment, and prevention of brain-related diseases.

 
 

Liane Hunter, BA 

Liane is a MD/PhD student at Albert Einstein College of Medicine. She received B.A in Psychology at Tufts University. Before Einstein, Liane worked as a Research Assistant at the New York State Psychiatric Institute at Columbia University where she worked on clinical trials and imaging studies relating to Obsessive Compulsive Disorder. For her doctoral studies, Liane wishes to pursue a concentration in Clinical Investigation and intends to complete her thesis work in our lab.

 
 

Cara LevitchCara Levitch, BA 

Cara is a third-year student in the clinical psychology doctoral program at Fordham University. She graduated with honors from Washington University in St. Louis in 2012 where she double majored in Philosophy, Neuroscience and Psychology (PNP) and Anthropology. After graduation, she worked as a Clinical Research Coordinator at the Mood and Anxiety Disorders Program at the Icahn School of Medicine at Mount Sinai, studying the efficacy and safety of a novel antidepressant for treatment-resistant depression. Cara is in the Neuropsychology Specialization at Fordham University and is interested in studying the relationship between brain and behavior in children and adults.

 
 

Tiago OliveiraTiago Gil Oliveira, MD, PhD 

Tiago Gil Oliveira was a student in the joint MD/PhD program of the University of Minho, Portugal and Columbia University, NYC, USA. He performed his PhD studies at Columbia University, between 2007 and 2010, under the supervision of Prof. Gilbert Di Paolo and his MD studies at University of Minho. While studying the role of lipid signaling in Alzheimer’s disease pathogenesis, he showed that the ablation of the lipid modulating enzyme, phospholipase D2, was protective in different Alzheimer’s disease models. Since 2011 he is an Assistant Professor at the School of Health Sciences, University of Minho, where he teaches Anatomy to medical students. While in Minho he expanded his research interests to the study of mood disorders. Using an unbiased lipidomic approach, he showed that specific lipid signaling pathways were altered in a chronic stress model, unraveling new potential therapeutic targets. In parallel with his academic work he continued his medical career and he is currently a Neuroradiology resident at Hospital de Braga.

 
 

Todd RubinTodd Rubin, BA 

Todd is an MD/PhD student at Albert Einstein College of Medicine. He received his B.A. from New York University in Biology and Chemistry in 2011. Before Einstein, Todd worked as a Research Assistant for Dr. Bruce McEwen in the Harold and Margaret Milliken Hatch Laboratory of Neuroendocrinology at The Rockefeller University where he studied transcriptional changes in the hippocampus following acute and chronic stress in models of genetic susceptibility. He is now interested in the mechanisms of injury and repair in mTBI and concussion.

 
 
 
 
 
 

Alumni

 

Undergraduate Students

Rose Shaine Abani, Yeshiva University

Anna Augustinos, University of Rochester

Bryanna Gulotta, Cornell (Einstein Summer Undergraduate Research Program (SURP))

Adina Sperling, New York University

Gabrielle Weinberg, Yeshiva University

 
 

Graduate Students

Sheldon Sloan, BA, Ferkauf Graduate School of Psychology (PhD)

Rachel Varon, BA 

 

Lauren Strainge, BA 

Lauren majored in neuroscience at Dartmouth College and is currently completing her Masters Degree in clinical psychology at Teachers College, Columbia University. She plans to pursue a PhD in neuropsychology next year. In the lab, Lauren is involved in processing imaging data for ongoing clinical research projects.

 

 

 

 

Residents & Fellows

 

Susan Sotardi, MD, MS  

 
 

Kevin Hsu, MD 

Kevin is a Resident in the Montefiore Medical Center Diagnostic Radiology Program. A native of California, he completed his undergraduate education at the University of California, San Diego and his medical education at Albert Einstein College of Medicine. He is interested in the detectable imaging signal changes with repetitive mild traumatic brain injury. He is an avid photographer with interests in new gadgets and nature.

 
 

Edwin Gulko, MD with distinction in research

 
 

Staff

Tamar Glattstein, BA 

Tamar is pursuing a clinical doctorate at Ferkauf Graduate School of Psychology. She is in the adult clinical program and is using all of the skills she learned about trauma and research. She was a research coordinator at the GMRRC for two years after graduating from Barnard College in 2013.

 

 

Ayelet Kahane, BA 

 

Margo Kahn, BA, Ferkauf Graduate School of Psychology (PsyD)

 

Hannah Scholl, BA, Ferkauf Graduate School of Psychology (PhD)

 

Malka Zughaft, BA 

 

 

 

 

 

Medical Students

Abby Bassalaley, MD, Albert Einstein College of Medicine

Avi Fink, Albert Einstein College of Medicine

Brandon Giglio, Albert Einstein College of Medicine

Miriam Hulkower, MD, Albert Einstein College of Medicine

Oren Jaspan, Albert Einstein College of Medicine

Daniel Krieger, MD with distinction in research Albert Einstein College of Medicine

Hilana Lewkowitz-Shpuntoff, Albert Einstein College of Medicine

Lisa Mogil, Albert Einstein College of Medicine

Weiya Mu, Albert Einstein College of Medicine

Young Park, MD, Albert Einstein College of Medicine

Daniel Poliak, Albert Einstein College of Medicine

Sara B. Rosenbaum, MD, with distinction in research Albert Einstein College of Medicine

Anna Shlionsky, MD Mount Sinai School of Medicine

Jonathan Weinberger, MD, Albert Einstein College of Medicine

 

 

 

 

Interns

Areeb KhanAreeb Khan 

Areeb is currently studying at Binghamton University and is pursuing a Bachelor's of Science in Integrative Neuroscience, and hopefully a business adjunct as well. He is working as a volunteer in Dr. Lipton's lab, collecting and organizing data for the MRI/DTI studies. He has previously done research for a startup involving disability. Areeb plans to apply to medical schools in the future in the hopes of becoming a physician one day.

   

   

   

Carly WolferCarly Wolfer 

Carly is a Howard Nemerov Scholar at Washington University in St. Louis double majoring in Psychological & Brain Sciences and Women's, Gender & Sexuality Studies with a minor in writing. During the year, she works as a research assistant at Wash U's Emotion & Relationships Lab. She is a sexual assault counselor for Wash U's crisis hotline and a domestic violence follow-up counselor for survivors at the St. Louis County Court. Carly plans to pursue a clinical psychology doctorate program in the future.

   

   

   

Delanie BomarDelanie Bomar 

Delanie is currently a student at Millennium High School, in Manhattan, and will be graduating in 2017. She holds many leadership positions at her school, including student government, and is passionate about making a difference in the world around her. Delanie's prior volunteer experience is with a non-profit working to end modern-day human trafficking. Her interest in concussion research has spiked over the last year since suffering her third concussion playing soccer at an elite level. Delanie is working with Dr. Lipton and the Einstein Soccer Study this summer, and plans to continue to pursue the path of concussion research and prevention in college.

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