Research
        

A. Studies on Myelodysplastic syndromes and Leukemia 

Myelodysplastic syndrome (MDS) are hematologic malignancies that are characterized by ineffective hematopoiesis. Even though these are preleukemic disorders that can transform to Acute Myeloid Leukemia in a third of cases, most of the morbidity is due to low blood counts. Our lab if focused in studying the molecular pathogenesis of myelodysplastic syndromes and identifying targetable pathways in this disease.

 
     

B. Development of assays for genome wide analysis of cytosine methylation and hydroxymethylation and their applications in tumor models. 

 
     

C. Clinical Studies:
In addition to these preclinical studies, Dr Verma is the director of a MDS Center of Excellence clinic (www.mdstreatment.com) at Einstein and Montefiore medical center and is the PI of various clinical trials in MDS and AML.

 
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