Professor and Founding Chair, Systems & Computational Biology
Professor, Dominick P. Purpura Department of Neuroscience
Evolutionary biologySystems biologyBiological modeling
Dr. Bergman combines data from basic and clinical research to create computer models of complex biological systems. As these models evolve, his work could contribute to calculating individualized medical outcomes and guiding treatment for patients based on their personal genetic make-up. Dr. Bergman has teamed with colleagues to study a variety of complex conditions, including aging, cancer and neurodegenerative diseases.
Central to his approach is an evolutionary perspective in examining the hypotheses arising from the combination of theoretical models and biological data. His studies have focused on the causes and consequences of “robustness” (an organism’s ability to withstand stresses, pressures or changes in its environment), the evolution of gene networks and the genetic hallmarks of human longevity and cancer as it relates to the loss of robustness.