Einstein Experts

Nir Barzilai, M.D.

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Professor, Medicine (Endocrinology)

Director, Institute for Aging Research

Director, Nathan Shock Center of Excellence in the Basic Biology of Aging

Ingeborg and Ira Leon Rennert Chair of Aging Research

AgingBiology of agingLongevity genes

Dr. Barzilai discovered the first “longevity gene” in humans. His research established that the gene variant that leads to high HDL, or “good cholesterol,” is linked to healthy aging and extreme longevity. Dr. Barzilai has been profiled by major outlets, including The New York Times and PBS’ “NOVA scienceNow.”

Treatments for age-related diseases like type 2 diabetes are being developed based on Dr. Barzilai’s work and are currently in clinical trials. In addition to his “longevity gene” research, Dr. Barzilai studies key mechanisms involved in the biology of aging, including how nutrients and genetics influence lifespan. He is also investigating the physical and mental declines associated with aging and how they affect longevity. Dr. Barzilai is professor of medicine (endocrinology) and of genetics, a member of the Diabetes Research Center and director of the Diabetes Research and Training Center’s Animal Physiology core.