Faculty Profile

Dr. Roee Holtzer, Ph.D.

Roee Holtzer, Ph.D.

Professor, The Saul R. Korey Department of Neurology

Areas of Research: Interests include: Neuropsychology, cognition, aging, dementia, neurodegenerative diseases, mobility, falls, rehabilitation.

Selected Publications

Select recent publications.*Denotes current or former students as co-authors

*Holtzer R, Jacobs S, Demetriou E. (2019). Intra-Individual Variability in Verbal Fluency
Performance is Moderated by and Predictive of Mild Cognitive Impairments. Neuropschology, [Epub ahead of print].

*Holtzer R, Kraut R, Ye, K. (2019). The effect of fear of falling on prefrontal cortex
activation and efficiency, GeroScience, 41:1, 89-100

*Wagshul ME, Lucas M, Izzetoglu M, Ye, K. Holtzer R. (2019). Multi-modal neuroimaging
of dual-task walking: Structural MRI and fNIRS analysis reveals prefrontal grey matter
volume moderation of brain activation in older adults, NeuroImage, 1:189, 745-754.

George CJ, Verghese J, Izzetoglu M, Wang C, Holtzer R. (2019). The effect of
polypharmacy on prefrontal cortex activation during single and dual-task walking in
community dwelling older adults. Pharmacological Research, 139, 113-119.

*Lucas M, Wagshul ME, Izzetoglu M, Holtzer R. (2019). Moderating Effect of White Matter
Integrity on Brain Activation During Dual-Task Walking in Older Adults. Journal of
Gerontology Biological Sciences, 74:4, 435-441. Editor’s Choice.

*Holtzer R, Izzetoglu M, Chen M, Wang C. (2019). Distinct fNIRS-derived HbO2 trajectories
during the course and over repeated walking trials under single and dual-task conditions:
implications for within session learning and prefrontal cortex efficiency in older adults. Journal
of Gerontology Medical Sciences, 18;74(7):1076-1083.

*Pillemer S, Ayers E, Holtzer R. (2018). Gender stratified analyses reveal longitudinal
associations between social support and cognitive decline in men. Aging and Mental Health,
17, 1-7.

Holtzer R, George CJ, Izzetoglu M, Wang C. (2018). The effect of diabetes on prefrontal
cortex activation patterns during active walking in older adults. Brain and Cognition, 125:14-

*Sleight C & Holtzer R. (2018). Differential associations of functional and cognitive health
outcomes with pre-frailty and frailty states in community-dwelling older adults. Journal of
Health Psychology, (Epud ahead of print).

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Research Information

In the News

The Wall Street Journal provides an in-depth look at research of  Dr. Joe Verghese and Dr. Roee Holtzer that has advanced our understanding of mobility and its link to cognition (subscription required).

Several Einstein faculty members and their research are featured in a National Geographic cover story on the potential genetic roots of longevity.

More media coverage