Faculty Profile

Dr. Solomon L. Moshe, M.D.

Solomon L. Moshe, M.D.

Professor, The Saul R. Korey Department of Neurology (Child Neurology)

Professor, Department of Pediatrics

Professor, Dominick P. Purpura Department of Neuroscience

Charles Frost Chair in Neurosurgery and Neurology

Director, Division of Pediatric Neurology, The Saul R. Korey Department of Neurology

Director, Division of Neurology, Department of Pediatrics

Director, Clinical Neurophysiology, The Saul R. Korey Department of Neurology

Areas of Research: The study of antiepileptogenesis following traumatic brain injury, intractable age specific epilepsies and their consequences, and subcortical circuits involving the control of seizures

Professional Interests

Solomon L. Moshé, M.D., is the Charles Frost Chair in Neurosurgery and Neurology, and Professor of Neurology, Neuroscience, and Pediatrics at the Albert Einstein College of Medicine/Montefiore Medical Center in the Bronx, New York. He is also the Vice Chair of the Saul R. Korey Department of Neurology, Director of the Isabelle Rapin Child Neurology Division and Director of Clinical Neurophysiology.

Since 1979 his research has focused on understanding the mechanisms underlying age and sex-related differences in epilepsy in humans and animal models.  The main goals are to develop individualized treatments today and to prevent and cure epilepsy tomorrow. In 2016, he and 6 other principal investigators were awarded a $21.7 Million Center Without Walls grant on interdisciplinary research aimed at accelerating the development of disease modifying or prevention therapies for epilepsy following traumatic brain injuries, titled the Epilepsy Bioinformatics Study for Antiepileptogenic Therapy (EpiBioS4Rx) study. His laboratory has also developed and patented a novel model of human infantile spasms that can be used to identify novel treatments of this devastating condition.  In addition to his laboratory research, he is actively involved in several large multicenter studies examining the consequences of prolonged febrile seizures.

He has served as President of the International League Against Epilepsy (2009-2011), the American Epilepsy Society (2000-2001), the American Clinical Neurophysiology Society (1996-1997) and the Eastern Association of EEGers (1992-1994). He is the recipient of several honors and awards, including the Teacher-Investigator Development Award from NINDS; the 1995 Jacob Javits Neuroscience Investigator Award from NINDS; the 1984 Michael Prize for Achievements in Epilepsy Research; the 1990 American Epilepsy Society Research Award; the 1999 Ambassador for Epilepsy Award from the International League Against Epilepsy; the 2005 Gloor Award from the American Clinical Neurophysiology Society; the 2007 J.E. Purkyne Honorary Medal in Biomedical Research by the Czech Academy of Sciences; the 2008 Mentor of the Year Award from Albert Einstein College of Medicine; the 2010 Global and Awareness Award from CURE, Citizens United for Research in Epilepsy; the First 2012 Saul R. Korey Award in Translational Science and Medicine, Albert Einstein College of Medicine, the 2017 Bernard Sachs Award from the Child Neurology Society and Foreign member of the Russian Academy of  Science.

Selected Publications

  1. Haas, K.Z., Sperber, E.F., & Moshé, S.L. Kindling in developing animals:  expression of severe seizures and enhanced development of bilateral foci. Brain Res Dev Brain Res. Nov 1 1990;56(2):275‑280. PMID 2261687
  2. Velíšková, J. & Moshé, S.L. Sexual dimorphism and developmental regulation of substantia nigra function. Ann Neurol. Nov 2001; 50(5):596-601. PMID 11706965
  3. Haas, K.Z., Sperber, E.F., Moshé, S.L., & Stanton, P.K. Kainic acid-induced seizures enhance dentate inhibition by down-regulation of GABAB receptors, J Neurosci. Jul 1 1996; 16(13):4250-4260. PMID 8753886
  4. Galanopoulou, A.S. & Moshé, S.L. Pathogenesis and new candidate treatments for infantile spasms and early life epileptic encephalopathies: A view from preclinical studies. Neurobiol. Disease. Jul 2015; 79:135-149. PMID 25968935
  5. Fisher, R.S., Acevedo, C., Arzimanoglou, A., Bogacz, A., Cross, J.H., Elger, C.E., Engel, J., Forsgren, L., French, J.A., Glynn, M., Hesdorffer, D.C., Lee, B.I., Mathern, G.W., Moshé, S.L., Perucca, E., Scheffer, I.E., Tomson, T., Watanabe, M. & Wiebe, S. A practical clinical definition of epilepsy. Epilepsia. Apr 2014; 55(4):475-82. PMID 24730690
  6. Scheffer IE, Berkovic S, Capovilla G, Connolly MB, French J, Guilhoto L, Hirsch E, Jain S, Mathern GW, Moshé SL, Nordli DR, Perucca E, Tomson T, Wiebe S, Zhang YH, Zuberi SM.  ILAE classification of the epilepsies: Position paper of the ILAE Commission for Classification and Terminology.  Epilepsia. 58:512-521 (2017) PMID 28276062
  7. Fisher R, Cross J, French J, Higurashi N, Hirsch E, Jansen F, Lagae L, Moshé SL, Peltola J, Roulet-Perez E, Scheffer I, Zuberi S.  Operational Classification of Seizure Types by the International League Against Epilepsy.  Epilepsia 58:522-530 (2017) PMID 28276060
  8. Galanopoulou AS, Engel J Jr, Moshe SL.    Preface: Antiepiletogenesis following traumatic brain injury.   Neurobiology of Disease 12: 1-2 (2019).   PMID: 30312758
  9. Saletti PG, Ali I, Casillas-Espinonsa PM, Semple BD, Lisgaras C, Moshe SL, Galanopoulou AS. In search of antiepileptogenic treatments for post-traumatic epilepsy.  Neurobiology of Disease 123: 86-99 (2019).  PMID: 29936231
  10. Correa DJ, Kwon C, Connors S, Fureman B, Whittemore V, Jette N, Mathern G and Moshe SL.   For the EpiBioS4RX Public Engagement Core.   Applying participatory action research in traumatic brain injury studies to prevent post-traumatic epilepsy.   Neurobiology of Disease 123: 137-144 (2019).  PMID: 30031158

More Information About Dr. Solomon Moshe

Developmental Epilepsy Laboratory

Clinical Programs in Child Neurology and Neurophysiology at Montefiore Medical Center

Material in this section is provided by individual faculty members who are solely responsible for its accuracy and content.

Albert Einstein College of Medicine
Rose F. Kennedy Center
1410 Pelham Parkway South , Room 316
Bronx, NY 10461

Tel: 718.430.2447

Research Information

In the News

The Washington Post interviews Dr. Solomon Moshé about the case of a girl with a rare form of epilepsy that causes uncontrolled bouts of laughter.

WebMD interviews Dr. Solomon Moshé about a new study that found treatment-resistant epilepsy is linked to autism.

More media coverage