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Faculty Profile

Hayley M. McDaid, Ph.D.

Dr. Hayley M. McDaid

Assistant Professor, Department of Medicine (Oncology)

Instructor, Department of Molecular Pharmacology

 

Professional Interests

My research is focused in the following areas:

1. The origins of oncogene dependence in RAS- and RAF- driven malignancies, (primarily lung cancer), and pharmacogenomic profiling utilizing RAS- and RAF-directed therapeutics, specifically MEK inhibitors.

2. Targeting oncogenic / mitogenic signaling in the RAS / PI3K signaling network using combinations of signaling inhibitors.

3. Exploiting feedback in cancer cell signaling for rational drug design.

4. Epigenetic mechanisms of drug-resistance (altered methylation and microRNA's): the long-term goal here is to identify such changes in Taxol-resistant cancer model systems and experimentally manipulate target genes to determine their overall contribution to the resistant phenotype.

5. Drug-induced accelerated senescence as a determinant of tumorigenic potential and response to therapy.

 

Material in this section is provided by individual faculty members who are solely responsible for its accuracy and content.

Contact

Albert Einstein College of Medicine
Jack and Pearl Resnick Campus
1300 Morris Park Avenue
Golding Building, Room 201
Bronx, NY 10461

Tel: 718.430.2192
hayley.mcdaid@einstein.yu.edu

 
Pubmed Search
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