Kami Kim, M.D.
Dr. Kim is Professor of Medicine (Infectious Diseases), of Microbiology & Immunology, and of Pathology. She runs a basic science laboratory focused upon understanding the pathogenesis of toxoplasmosis and malaria. Recently she has developed collaborations with clinical investigators at the Blantyre Malaria Project in Malawi to understand the clinical impact of HIV co-infection upon cerebral malaria. She is also interested in understanding epigenetic and genetic factors that govern the host response to parasitic infections, opportunistic pathogens and tuberculosis. Dr. Kim is co-director of the NIH-funded Training Program in Geographic Medicine and Emerging Infections (with Dr. Herb Tanowitz) that supports graduate students and post-doctoral fellows (MD or PhD) pursuing mentored basic science and translational global infectious diseases research.
Dr. Kim graduated magna cum laude in biology from Harvard University and received her medical degree from the Columbia College of Physicians and Surgeons. She trained in internal medicine at Columbia Presbyterian Medical Center and in infectious diseases at University of California, San Francisco. Following her clinical training, she did a postdoctoral fellowship in the Department of Microbiology & Immunology at Stanford University School of Medicine, after which she joined the faculty at Einstein in the departments of medicine, microbiology and immunology and pathology.
- Ting LM, Shi W, Lewandowicz A, Singh V, Mwakingwe A, Birck MR, Ringia EA, Bench G, Madrid DC, Tyler PC, Evans GB, Furneaux RH, Schramm VL*, Kim K*. Targeting a novel Plasmodium falciparumpurine recycling pathway with specific immucillins.J Biol Chem. 2005 Mar 11;280(10):9547-54. Epub 2004 Dec 2.PMID: 15576366 *joint corresponding
- Jongco AM, Ting LM, Thathy V, Mota MM, Kim K.Improved transfection and new selectable markers for the rodent malaria parasite Plasmodium yoelii. Mol Biochem Parasitol. 2006 Apr;146(2):242-50. Epub 2006 Jan 17. PMID: 16458371
- Gissot M, Kelly KA, Ajioka JW, Greally JM, Kim K. Epigenomic modifications predict active promoters and gene structure in Toxoplasma gondii. PLoS Pathog. 2007 Jun;3(6):e77. PMID: 17559302
- Gissot M, Ting LM, Daly TM, Bergman LW, Sinnis P, Kim K. High mobility group protein HMGB2 is a critical regulator of Plasmodium oocyst development. J Biol Chem. 2008 Apr 8; [Epub ahead of print] PMID: 18400754
- Thompson RF, Reimers M, Khulan B, Gissot M, Richmond TA, Chen Q, Zheng X, Kim K, Greally JM. An analytical pipeline for genomic representations used for cytosine methylation studies. Bioinformatics. 2008 Mar 18; [Epub ahead of print] PMID: 18353789
- Binder EM, Lagal V, Kim K. The prodomain of Toxoplasma gondii GPI-anchored subtilase TgSUB1 mediates its targeting to micronemes. Traffic. 2008 Jun 2. [Epub ahead of print] PMID: 18532988
- Ting LM, Gissot M, Coppi A, Sinnis P, Kim K. Attenuated Plasmodium yoelii lacking purine nucleoside phosphorylase confer protective immunity. Nat Med. 2008 Sep;14(9):954-8.PMID: 1875844
- Madrid DC, Ting LM, Waller KL, Schramm VL, Kim K. Plasmodium falciparum purine nucleoside phosphorylase is critical for viability of malaria parasites. J Biol Chem. 2008 Dec 19;283(51):35899-907. Epub 2008 Oct 28. PMID: 18957439
- Dybas JM, Madrid-Aliste CJ, Che FY, Nieves E, Rykunov D, Angeletti RH, Weiss LM, Kim K, Fiser A. Computational Analysis and Experimental Validation of Gene Predictions in Toxoplasma gondii. PLoS ONE. 2008;3(12):e3899. Epub 2008 Dec 9. PMID: 19065262
- Madrid-Aliste CJ, Dybas JM, Hogue Angeletti R, Weiss LM, Kim K, Simon I, FiserA. EPIC-DB: a proteomics database for studying Apicomplexan organisms. BMC Genomics. 2009 Jan 21;10(1):38. [Epub ahead of print] PMID: 19159464
- MwakingweA, Ting LM, HochmanS, ChenJ, SinnisP, KimK. Non-Invasive Real-Time Monitoring of Liver Stage Development of Bioluminescent Plasmodium Parasites. J Infect Dis. 2009 Nov 1;200(9):1470-8. PMID: 19811100
- Lagal V, Binder EM, Diez R, Chen D, Kafsack BFC, Cole R, Carruthers VB, Kim K. Toxoplasma gondii protease TgSUB1 is required for surface processing of micronemal adhesive complexes that mediate host cell attachment and invasion. Cell Microbiol. 2010 Jul 30. [Epub ahead of print] PMID: 2067817
- Che, FY, Madrid-AlisteC BurdB, ZhangH, NievesE, KimK, FiserA, AngelettiRH, WeissLM, Comprehensive Proteomic Analysis of Membrane Proteins in Toxoplasma gondii. Mol Cell Prot. 2011 Jan;10(1):M110.000745. Epub 2010 Oct 10.PMID: 20935347
- Brooks CF, Francia ME, Gissot M, Croken MM, Kim K*, Striepen B*. Toxoplasmagondii sequesters centromeres to a specific nuclear region throughout the cell cycle. Proc Nat Acad Sci 2011 March 1; 108(9):3767-72. Epub 2011 Feb 14.*joint corresponding PMID: 21321216
- Vera IM, Beatty WL, Sinnis P, Kim K. The Plasmodium yoelii rhomboid protease ROM1 is critical for proper parasitophorous vacuole formation. PLoS Pathog. 2011 Sep;7(9):e1002197. Epub 2011 Sep 1. PubMed PMID: 21909259; PubMed Central PMCID: PMC3164628.
- Suvorova ES, CrokenMM, KratzerS, Conde de Felipe M, BaluB, Markville LM, WeissLM, Kim K, White MW. Discovery of a splicing regulator required for cell cycle progression. PLoS Genet. 2013 Feb;9(2):e1003305. doi: 10.1371/journal.pgen.1003305. Epub 2013 Feb 21.PMID: 23437009
- Walker R,GissotM, Croken MM, HuotL, HotD, KimK, TomavoS. The Toxoplasma nuclear factor TgAP2XI-4 controls bradyzoite gene expression and cyst formation. Mol Microbiol. 2013 Feb;87(3):641-55. doi: 10.1111/mmi.12121. Epub 2012 Dec 26.PMID: 23240624
- NardelliSC, Fa-Yun Che FY, Silmon de MonerriNC, XiaoH, NievesE, Madrid-AlisteC, Angel S, Sullivan WJ, AngelettiRH, Kim K*, Weiss LM*. The Histone Code of Toxoplasma gondii Comprises Conserved and Unique Post-translational Modifications. Submitted. *joint corresponding
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