Faculty Profile

Dr. Howard Strickler, M.D.

Howard Strickler, M.D.

Professor, Department of Epidemiology & Population Health

Harold and Muriel Block Chair in Epidemiology & Population Health

Division Head, Division of Epidemiology, Department of Epidemiology & Population Health

Co-Leader, Cancer Epidemiology Program, Albert Einstein Cancer Center

Professional Interests

Primary research interests involve viral and cancer epidemiology, especially as it relates to:

  1. The viral causes of cancer such as human papillomavirus (HPV) and hepatitis C virus (HCV)
  2. Immunogenetic factors that influence viral infection with HPV, human immunodeficiency virus (HIV), and hepatitis C virus (HCV)
  3. The hormonal and growth factors influences on viral pathogenesis and tumorigenesis. These include obesity, diabetes, the insulin / insulin-like growth factor axis, sex hormones, and related pathways.

Selected Publications

 

Gradíssimo A, Lam J, Attonito JD, Palefsky J, Massad LS, Xie X, Eltoum IE, Rahangdale L, Fischl MA, Anastos K, Minkoff H, Xue X, D'Souza G, Flowers LC, Colie C, Shrestha S, Hessol NA, Strickler HD*, Burk RD* (*dual senior authors). Methylation of High-Risk Human Papillomavirus Genomes are Associated with Cervical Precancer in HIV-positive Women. Cancer Epidemiol Biomarkers Prev. In Press.

Hosgood HD, Gunter MJ, Murphy N, Rohan TE, Strickler HD. The Relation of Obesity-Related Hormonal and Cytokine Levels With Multiple Myeloma and Non-Hodgkin Lymphoma. Front Oncol. 2018 Apr 16;8:103. doi: 10.3389/fonc.2018.00103. eCollection 2018. Review. PubMed PMID: 29713614; PubMed Central PMCID: PMC5911620.

Robbins HA, Strickler HD, Massad LS, Pierce CB, Darragh TM, Minkoff H, Keller MJ, Fischl M, Palefsky J, Flowers L, Rahangdale L, Milam J, Shrestha S, Colie C, DʼSouza G. Cervical cancer screening intervals and management for women living with HIV: a risk benchmarking approach. AIDS. 2017 Apr 24;31(7):1035-1044. doi:10.1097/QAD.0000000000001450. PubMed PMID: 28323758; PubMed Central PMCID: PMC5531443.

Xie X, Xue X, Strickler HD. Generalized linear mixed model for binary outcomes when covariates are subject to measurement errors and detection limits. Stat Med. 2018 Jan 15;37(1):119-136. PMCID: PMC5720942.

Nevadunsky NS, Van Arsdale A, Strickler HD, Spoozak LA, Moadel A, Kaur G, Girda E, Goldberg GL, Einstein MH. Association Between Statin Use and Endometrial Cancer Survival. Obstet Gynecol. [in press]

Xue X, Agalliu I, Kim MY, Wang T, Lin J, Ghavamian R, Strickler HD. New methods for estimating follow-up rates in cohort studies. BMC Med Res Methodol. 2017 Dec 1;17(1):155. doi: 10.1186/s12874-017-0436-z. PubMed PMID: 29191174;PubMed Central PMCID: PMC5709923.

Murphy N, Xu L, Zervoudakis A, Xue X, Kabat G, Rohan TE, Wassertheil-Smoller S, O'Sullivan MJ, Thomson C, Messina C, Strickler HD, Gunter MJ. Reproductive and menstrual factors and colorectal cancer incidence in the Women's Health Initiative Observational Study. Br J Cancer. 2017 Jan 3;116(1):117-125. doi:10.1038/bjc.2016.345. Epub 2016 Nov 29. PubMed PMID: 27898658; PubMed CentralPMCID: PMC5220139.

Reimers LL, Mehta SD, Massad LS, Burk RD, Xie X, Ravel J, Cohen MH, Palefsky JM, Weber KM, Xue X, Anastos K, Minkoff H, Atrio J, D'Souza G, Ye Q, Colie C, Zolnik CP, Spear GT, Strickler HD. The Cervicovaginal Microbiota and Its Associations With Human Papillomavirus Detection in HIV-Infected and HIV-Uninfected Women. J Infect Dis. 2016;214:1361-1369. PMCID: PMC507936

Massad LS, Xie X, Burk RD, D'Souza G, Darragh TM, Minkoff H, Colie C, Burian P, Palefsky J, Atrio J, Strickler HD. Association of cervical precancer with human papillomavirus types other than 16 among HIV co-infected women. Am J Obstet Gynecol. 2016 Mar;214(3):354.e1-6. doi: 10.1016/j.ajog.2015.09.086. Epub 2015 Nov 14. PubMed PMID: 26433170; PubMed Central PMCID: PMC4775397

Keller MJ, Burk RD, Massad LS, Eltoum IE, Hessol NA, Castle PE, Anastos K, Xie X, Minkoff H, Xue X, D’Souza G, Flowers L, Levine AM, Colie C, Rahangdale L, Fischl MA, Palefsky JM, Strickler HD. Cervical Precancer Risk in HIV-Infected Women Who Test Positive for Oncogenic Human Papillomavirus Despite a Normal Pap Test. Clin Infect Dis  2015, 15;61:1573-81.PMCID:PMC4614409

Gunter MJ, Xie X, Xue X, Kabat GC, Rohan TE, Wassertheil-Smoller S, Ho GY, Wylie-Rosett J, Greco T, Yu H, Beasley J, Strickler HD. Breast cancer risk in metabolically healthy but overweight postmenopausal women. Cancer Res. 2015, 75:270-4. PMCID:PMC4657855

Agalliu I, Williams S, Adler B, Androga L, Siev M, Lin J, Xue X, Huang G, Strickler HD*, Ghavamian R* [*both senior authors contributed equally]. The impact of obesity on prostate cancer recurrence observed after exclusion of diabetics. Cancer Causes Control. 2015, 26:821-30. PMCID:PMC498440

Gunter MJ, Wang T, Cushman M, Xue X, Wassertheil-Smoller S, Strickler HD, Rohan TE, Manson JE, McTiernan A, Kaplan RC, Scherer PE, Chlebowski RT, Snetselaar L, Wang D, Ho GY. Circulating Adipokines and Inflammatory Markers and  Postmenopausal Breast Cancer Risk. J Natl Cancer Inst. 2015, 107; PMCID: PMC4651104.

Xue X, Kim MY, Castle PE, Strickler H. A new method to address verification bias in studies of clinical screening tests: cervical cancer screening assays as  an example. J Clin Epidemiol. 2014;67:343-53. PMCID: PMC3946800.

Keller MJ, Burk RD, Xie X, Anastos K, Massad LS, Minkoff H, Xue X, D'Souza G, Watts DH, Levine AM, Castle PE, Colie C, Palefsky JM, Strickler HD. Risk of cervical precancer and cancer among HIV-infected women with normal cervical cytology and no evidence of oncogenic HPV infection. JAMA. 2012 Jul 25;308(4):362-9. doi: 10.1001/jama.2012.5664. PMCID: PMC3556987.

Minkoff H, Zhong Y, Burk RD, Palefsky JM, Xue X, Watts DH, Levine AM, Wright RL, Colie C, D'Souza G, Massad LS, Strickler HD. Influence of adherent and effective antiretroviral therapy use on human papillomavirus infection and squamous intraepithelial lesions in HIV-positive women. J Infect Dis. 201: 681-690, 2010.

Gunter MJ, Hoover DR, Yu H, Wassertheil-Smoller S, Rohan TE, Manson JE, Li J, Ho GYF, Xue X, Anderson GL, Kaplan RC, Harris TG, Howard BV, Wylie-Rosett J, Burk RD, Strickler HD. Insulin, Insulin-like Growth Factor-I, and Risk of Breast Cancer in Postmenopausal Women. J Natl Cancer Inst. 101: 48-60, 2009.

More Information About Dr. Howard Strickler

Strickler Webpage

Department of Epidemiology and Population Health

Material in this section is provided by individual faculty members who are solely responsible for its accuracy and content.

Albert Einstein College of Medicine
Jack and Pearl Resnick Campus
1300 Morris Park Avenue
Belfer Building, Room 1312A
Bronx, NY 10461

Tel: 718.430.4055
Fax: 718.430.8780

Research Information

In the News

Reuters and Medscape report on a study led by Dr. Marc Gunter in conjunction with senior author Dr. Howard Strickler, which found that high insulin levels are an independent risk factor for breast cancer, particularly among postmenopausal women who did not use hormone therapy.

More media coverage