Faculty Profile

Dr. Wei Chen, M.D.

Wei Chen, M.D.

Assistant Professor, Department of Medicine (Nephrology)

Areas of Research: Vascular calcification in chronic kidney disease; vascular smooth muscle cell function; disorders of mineral metabolism in chronic kidney disease; metabolism of calcium, phosphate and magnesium; biomarker development

Professional Interests

Dr. Wei Chen completed the internal medicine residency and nephrology fellowship at Montefiore Medical Center.  During the fellowship, she earned a Master of Science in Clinical Research with Distinction through Einstein’s Clinical Research Training Program. 

Dr. Chen's research focuses on disorders of mineral metabolism in patients with chronic kidney disease, especially vascular calcification. Using the bench to bedside translational approach, she studies pathophysiology and develops biomarkers of vascular calcification in patients with chronic kidney disease. 

Dr. Chen was awarded Career Development Award from the University of Rochester Clinical and Translational Science Institute (2015-2017) and research grant from Renal Research Institute (2015-2017), Carl Gottschalk Research Scholar Grant from the American Society of Nephrology (2017-2019) and K23 Career Development Award from the National Institutes of Health (2018-2022).

 

Selected Publications

RESEARCH ARTICLES

Chen W, Eisenberg R, Mowrey WB, Wylie-Rosett J, Abramowitz MK, Bushinsky DA, Melamed ML. “Association Between Dietary Zinc Intake and Abdominal Aortic Calcification in US Adults.” Nephrology Dialysis Transplantation, 2019 [In press]

Chen W, Fitzpatrick J, Monroy-Trujillo JM, Sozio SM, Jaar BJ, Estrella MM, Wu TT, Melamed ML, Parekh RS, Bushinsky DA. “Diabetes Mellitus Modifies the Associations of Serum Magnesium Concentration with Arterial Calcification and Stiffness in Incident Hemodialysis Patients”. Kidney International Reports, 2019. DOI: https://doi.org/10.1016/j.ekir.2019.03.003

Chen W, Anokhina V, Dieudonne G; Abramowitz MK, Kashyap R, Yan C, Wu TT, Bentley KL, Miller B,  Bushinsky DA. "Patients with Advanced Chronic Kidney Disease and Vascular Calcification Have a Large Hydrodynamic Radius of Secondary Calciprotein Particles". Nephrology Dialysis Transplantation (2018). Doi:10.1093/ndt/gfy117. PMID: 29788425

Chen W, Newman AB, Fried LF, Rifkin DE, Shlipak M, Sarnak MJ, Katz R, Madero M, Raphael KL, Bushinsky DA, Ix JH. "Relationship of Acid-Base Status with Arterial Stiffness in Community-Living Elders: the Health ABC Study". Nephrology Dialysis Transplantation (2017) 1-8. Doi: 10.1093/ndt/gfx292. PMID: 29177410.

Chen W, Melamed ML, Hostetter TH, Bauer C, Raff AC, Almudevar AL, Lalonde A, Messing S, Abramowitz MK. "Effect of Oral Sodium Bicarbonate on Fibroblast Growth Factor-23 in Patients with Chronic Kidney Disease: A Pilot Study". BMC Nephrology (2016) 17:114. PMID: 27495287.

Chen W, Melamed ML, Abramowitz MK. "Serum Bicarbonate Level and Bone Mineral Density in the United States Adults". American Journal of Kidney Disease, 2015 Feb;65(2):240-8. PMID: 25168294.

REVIEW ARTICLES AND EDITORIALS

Chen W, Abramowitz MK. “Advances in management of chronic metabolic acidosis in CKD.” Current Opinion in Nephrology and Hypertension. 2019 [In press]

Chen W, Levy DS, Abramowitz MK. "Acid-base Balance in the Progression of Chronic Kidney Disease". Seminars in Nephrology, 2019 [In press]

Hugh A, Chen W, Karim M, Sai R. "Chronic Kidney Disease in Pregnancy". PeriFacts OB/GYN Academy, 2018 

Chen W, Bushinsky DA. "Addressing Racial Disparity in the Progression of CKD: Prescribe More Fruits and Vegetables?" Am J Nephrol. 2018 Mar 13;47(3):171-173. doi: 10.1159/000487716. PMID: 29533958.

Chen W, Bushinsky DA. "KDIGO CKD-MBD Guideline Update: Evolution in the Face of Uncertainty". Nature Reviews Nephrology. 2017 Aug 21. doi: 10.1038/nrneph.2017.118. [Epub ahead of print] PubMed PMID: 28824172.

Chen W, Abramowitz MK. "Epidemiology of Acid-Base Derangements in CKD. Advances in Chronic Kidney Disease". Adv Chronic Kidney Dis. 2017;24(5):280-288. PMID: 29031354.

Chen W, Bushinsky DA. "The Perils of a Falling PTH due to High Dialysate Calcium". Nature Reviews Nephrology, 2016 May; 12(5):264-6. doi:10.1038/nrneph.2016.36. PMID: 26996329.

Chen W, Melamed ML. "Vascular Calcification in Pre-Dialysis CKD: Common and Deadly". Clinical Journal of the American Society of Nephrology, 2015 Apr 7;10(4):551-3.

Chen W, Kayler LK, Zand MS, Muttana R, Chernyak V, DeBoccardo GO. "Transplant Renal Artery Stenosis: Clinical Manifestation, Diagnosis and Therapy". Clinical Kidney Journal, 2015 Feb;8(1):71-8.

Chen W, Abramowitz MK. "Metabolic Acidosis and the Progression of Chronic Kidney Disease". BMC Nephrology, 15:55, 2014. PMID: 24708763.

Chen W, Abramowitz MK. "Treatment of Metabolic Acidosis in Patients with Chronic Kidney Disease, an Acid-Base and Electrolyte Teaching Case", American Journal of Kidney Disease, 63(2):311-317, 2014. PMID: 23932089.

BOOK CHAPTERS

Chen W, Bushinsky DA. Handbook of Dialysis Therapy. 5th edition. Nissenson AR, Fine RN, editors. Chapter 59. "Overview of Chronic Kidney Disease and Bone Disorder". 

Chen W, Monk RD, Bushinsky DA. Comprehensive Clinical Nephrology. 6th edition. Johnson RJ, Feehally J, Floege J, editors. Chapter 57. "Nephrolithiasis and Nephrocalcinosis". 

Research Images

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More Information About Dr. Wei Chen

Chen Bibliography

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Albert Einstein College of Medicine
Jack and Pearl Resnick Campus
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Research Information