Aaron A.J. Golden, Ph.D.

Genome, Epigenome and Microbiome Informatics

The digitization of genetic information coupled with recent developments in high throughput sequencing technologies have revolutionized the life sciences, and the discipline of genetics in particular. The Golden Lab is dedicated to the development of innovative, scalable algorithms and software to process and interpret the vast amounts of data generated by these sequencing platforms and other high-throughput biological assays. We do this by combining many different strands in computational science ranging from algorithmic development, high-performance computing and hardware optimization, to the application of techniques in artificial intelligence and computer vision.

We actively collaborate with many members of the Einstein research community, on areas as diverse as aptamer design, metabolomic profiling, integrative epigenomics and probing the (truly) dark matter that are the numerous human microbiomes.

Much of the group's research relies on High-Performance Computing resources and hardware accelerators. Our symmetric multiprocessing cluster, 'Leo', is an SGI Altix UV1000 with 64-cpus, 4 Nvidia Tesla GPUs and 1.5TB of fully addressable RAM.  Leo is named for Leo Szilard, the Hungarian physicist and humanist, who was one of Einstein’s closest friends and collaborators.