Zhengdong Zhang, Ph.D.

The research interests of my lab are computational biology and bioinformatics, focusing on algorithm development, data integration, and software implementation. The biological system currently under investigation is breast cancer metastasis, a complex multi-step process during which tumor cells spread from the primary tumor mass to distant organs. To study the genetic and biochemical determinations of this deadly aspect of cancer progression, we analyze various microarray and sequencing profiles to discover its regulatory sub-networks, DNA binding of key regulators, and copy number variations during the progression.