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Faculty Profile

Dibyendu Samanta, Ph.D.

Dr. Dibyendu Samanta
 

Professional Interests

Structure-function studies of T cell costimulatory molecules

Protein engineering for immunotherapy

Molecular basis of cell-cell adhesion

 

Selected Publications

Samanta D, Ramagopal UA, Rubinstein R, Vladimir V, Nathenson SG, Almo SC. Structure of Nectin-2 reveals determinants of homophilic and heterophilic interactions that control cell-cell adhesion, Proc Natl Acad Sci USA, 2012, 109(37):14836-40. (Highlighted in PSI-Nature Structural Biology Knowledgebase, March 2013)

Das D, Samanta D, Hasan S, Das A, Bhattacharya A, Dasgupta S, Chakrabarti A, Ghorai P, DasGupta C. Identical RNA-protein interactions in vivo & in vitro and a scheme of folding the newly synthesized proteins by ribosomes, J Biol Chem, 2012, 287(44):37508-21.

Samanta D§, Mukherjee G§, Ramagopal UA, Chaparro RJ, Nathenson SG, DiLorenzo TP, Almo SC. Structural and Functional Characterization of a Single-chain Peptide-MHC Molecule that Modulates Both Naive and Activated CD8+ T Cells, Proc Natl Acad Sci USA, 2011, 108(33): 13682-87.

Samanta D*, Das A, Das D, Bhattacharya B, Basu A, Ghosh G, DasGupta C*. Ribosome Assisted Protein Folding: Some of its Biological Implications, Protein Folding, Nova Science Publisher, New York (book chapter), 2010.

Samanta D*, Das A, Bhattacharya A, Basu A, Das D, DasGupta C*. Mechanism of ribosome assisted protein folding: a new insight into rRNA functions, Biochem Biophys Res Commun, 2009, 384(2):137-40.

Samanta D, Mukhopadhyay D, Chowdhury S, Ghosh J, Pal S, Basu A, Bhattacharya A, Das A, Das D, DasGupta C. Protein folding by domain V of Escherichia coli 23S rRNA: specificity of RNA-protein interactions, J Bacteriol, 2008, 190(9):3344-52.

Basu A§, Samanta D§, Bhattacharya A, Das A, Das D, Dasgupta C. Protein folding following synthesis in vitro and in vivo: association of newly synthesized protein with 50S subunit of E. coli ribosome, Biochem Biophys Res Commun, 2008, 366(2):592-97.

[§ Equally Contributed   *Corresponding Author]

 

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Contact

Albert Einstein College of Medicine
Jack and Pearl Resnick Campus
1300 Morris Park Avenue
Ullmann Building, Room 409
Bronx, NY 10461

Tel: 718.430.2745
Fax: 718.430.8565
dibyendu.samanta@einstein.yu.edu