Mark H. Kuniholm, Ph.D.

My research examines the role of immune gene variation in relation to HIV and hepatitis C virus (HCV) pathogenesis. This knowledge is clinically important because it can provide evidence that specific molecular pathways affect pathogenesis – an important step in determining molecular targets that could be exploited to develop new treatments and preventive strategies related to these infections. There is also considerable interest in using host genetic data to “personalize” management and treatment of HIV and HCV.