My research focuses on epigenomics, genomics and cell signaling. My research specialties include massively-parallel sequencing (MPS) using high-throughput technologies available such as Illumina HiSeq 2500 and Roche Genome Sequencer FLX (454), NimbleGen microarray and Sequence Capture or targeted resequencing technology using multiple platforms, quantitative Real Time-PCR (qPCR), data analysis and bioinformatics. Also experienced in web designing as well as SQL languages and programming. I have generated and utilized genomic resources to reveal the molecular, genetic and biochemical mechanisms regulating growth, development, metabolisms and stress/defense responses to various biotic and abiotic stresses in bacteria, fungi, plants and Drosophila.
- McPike, M.P., Maqbool, S.B., Chen, L., Ouyang, W., Borer, P.N. Parallel analysis of protein binding to DNA libraries using multiplexed microarray chips. Nucleic Acid Research (NAR): 2011. (In Press)
- Maqbool, S.B., Mehrotra, S., Kolpakas, A, Durden, C., Zhang, B, Zhong, H. and Calvi, B.R. Dampened activity of E2F1–DP and Myb–MuvB transcription factors in Drosophila endocycling cells. J. Cell Science 123: 4095-4106, 2010.
- Maqbool, S.B., Zhong, H., Oraby, F.H. and Sticklen, M.B. Transformation of oats and its application to improving osmotic stress tolerance. In: ed. (Huw D. Jones and Peter R. Shewry), Transgenic Wheat, Barley and Oats: Production and Characterization Protocol Methods in Molecular Biology, Vol . 478, pp. 149-168, 2009.
- Mehrotra, S., Maqbool, S.B., Kolpakas, A, Murnen, K. and Calvi, B.R. Endocycling cells do not apoptose in response to DNA re-replication genotoxic stress. Genes & Development 22: 3158-3171, 2008.
- Jagadeeswaran, G., Raina, S., Biswa R. Acharya, B.R., Maqbool, S.B., Mosher, S.L., Appel, H.M., Schultz, J.C., Klessig, D.F., Raina, R., Arabidopsis GH3-LIKE DEFENSE GENE 1 is required for accumulation of salicylic acid, activation of defense responses and resistance to Pseudomonas syringae. The Plant Journal 51:234-246, 2007.
- Maqbool, S.B., Ahmad, A., Hashsham, S.A. Detection and quantification of phosphorus removing microorganisms in wastewater treatment plants using Real Time PCR. Research Journal of Environmental Sciences 1: 229-236, 2007.
- Acharya, B. R., Raina, S., Maqbool, S.B., Jagadeshwaran, G., Appel, H.M., Schultz, J.C., Klessig, D.F. Raina, R., Overexpression of CRK13, an Arabidopsis cysteine-rich receptor-like kinase, results in enhanced resistance to Pseudomonas syringae. The Plant Journal 50:488-499, 2007.
- Maqbool, S.B., Ahmad, A., Dhawan, A., Callister, S.J., Tsoi, T., Sticklen, M.B., Hashsham, S.A. Response of selected genes of Burkholderia xenovorans strain LB400 to onion extract using a DNA:RNA hybrid capture detection system. Research Journal of Microbiology 1:378-391, 2006.
- Ahmad, A., Maqbool, S.B., Hashsham, S.A., Sticklen, M.B. Determination of cryIAb and cryIAc copy number in transgenic Basmati 370 Rice (Oryza sativa L.) plants using Real-time PCR and its comparison with Southern Blot. Journal of Biological Sciences 5:283-288, 2005.
More Information About Dr. Shahina Maqbool
Epigenomics Shared Facility
Center for Epigenomics
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