Faculty Profile

Dr. Moonseong Heo, Ph.D.

Moonseong Heo, Ph.D.

Clinical Professor, Department of Epidemiology & Population Health

Areas of Research: Sample size determination for broad types of cluster randomized clinical trials including stepped-wedge designs; meta-analysis; mixed-effects regression models; epidemiology of obesity; and statistical consulting

Professional Interests

My statistical research interest includes: sample size determinations for clinical trials including cluster randomized trials and stepped-wedge trial; meta-analysis; longitudinal data analysis applying mixed-effects models; handling attrition problems in clinical trials data; and statistical consulting and mentoring.  I am also interested in epidemiology research in the field of obesity, HIV and HCV infections.  

Selected Publications

Heo M, Kim N, Rinke ML, Wylie-Rosett J. Sample size determinations for stepped wedge clinical trials from a three-level data hierarchy perspective. Statistical Methods in Medical Research (in press)

Heo M, Litwin AH, Blackstock O, Kim N, Arnsten JH. Sample size determinations for randomized clinical trials with different levels of data hierarchy between experimental and control arms. Statistical Methods in Medical Research (in press)

Heo M, Irvin E, Ostrovsky NW, Isasi C, Blank AE, Lounsbury D, Fredericks L, Yom T, Ginsberg M, Hayes S, Wylie-Rosett J. (2016) Behaviors and knowledge of HealthCorps New York City high school students: nutrition, mental health and physical activity. Journal of School Health, 86, 84-95

Heo M, Kim N, Faith MS. (2015) Statistical power as a function of Cronbach alpha of instrument questionnaire items. BMC Medical Research Methodology, 15, 86.

Heo M, Kabat GC, Strickler H, Lin J, Hou L, Stefanick ML, Anderson, G, Rohan TE. (2015) Optimal cutoffs of obesity measures in relation to cancer risk in postmenopausal women in the Women’s Health Initiative Study. Journal of Women’s Health, 24, 217-227.

Ahn C, Heo M, Zhang S. (2014) Sample size calculations for clustered and longitudinal outcomes in clinical research. Chapman & Hall/CRC Biostatistics Series: New York

Heo M, Xue X, Kim MY. (2014) Sample size requirements to detect a two- or three-way interaction in longitudinal cluster randomized clinical trials with second level randomization. Clinical Trials, 11, 503-507.

Heo M. (2014) Impact of subject attrition on sample size determinations for longitudinal cluster randomized clinical trials. Journal of Biopharmaceutical Statistics, 24, 507-522

Heo M, Wylie-Rosett J, Pietrobelli A, Kabat GC, Rohan TE, Faith MS. (2014) US Pediatric population-level associations of DXA-measured percentage of body fat with four BMI metrics with cutoffs. International Journal of Obesity, 38, 60-8

Heo M, Kabat GC, Gallagher D, Heymsfield SB, Rohan TE. (2013) Optimal scaling of weight and waist circumference to height for maximal association with DXA-measured total body fat mass by sex, age, and race/ethnicity. International Journal of Obesity, 37:1154-60

Heo M, Leon AC. (2013) Comparison of post hoc multiple pairwise testing procedures as applied to small k-group logrank tests. International Journal of Statistics in Medical Research, 2, 104-116

Heo M, Xue X, Kim MY. (2013) Sample size requirements to detect an intervention by time interaction in longitudinal cluster randomized clinical trials with random slopes. Computational Statistics and Data Analysis, 60, 169-178

Heo M, Faith MS, Pietrobelli A, Heymsfield SB. (2012) Percentage of body fat cutoff by sex, age and race/ethnicity in the US population from the NHANES 1999-2004. American Journal of Clinical Nutrition, 95, 594-602

Meyers BS, Flint AJ, Rothschild AJ, Mulsant BH; Whyte EM, Peasley-Miklus C. Papademetriou E, Leon AC, Heo M, for the STOP-PD Study Group. (2009) A double-blind randomized controlled trial of olanzapine plus sertraline versus olanzapine plus placebo for psychotic depression—the STOP-PD study.  Archives of General Psychiatry, 66, 838-847

Heo M, Leon AC (2008). Statistical power and sample size requirements for three level hierarchical cluster randomized trials. Biometrics, 64, 1256-1262

Heo M, Murphy C, Meyers BS. (2007) Relationship between HDRS and MADRS in depressed elderly: A meta-analysis. American Journal of Geriatric Psychiatry, 15, 899-905

Heo M, RL Leibel, Fontaine KR, BB Boyer, WK Chung, M Koulu, MK Karvonen, U Pesonen, A Rissanen, M Laakso, MIJ Uusitupa, Y Chagnon, C Bouchard, PA Donohoue, TL Burns, AR Shuldiner, K Silver, RE Andersen, O Pedersen, S Echwald, TIA Sørensen, P Behn, MA Permutt, KB Jacobs, RC Elston, DJ Hoffman, E Gropp, DB Allison. (2002) A meta-analytic investigation of linkage and association of common leptin receptor polymorphisms with body mass index and waist. International Journal of Obesity, 26, 640-646

Heo M, Gabriel KR. (2001) The fit of graphical displays of data to patterns of expectations. Computational Statistics and Data Analysis, 36, 47-67

Allison DB, Mentore JL, Heo M, Chandler LP, Cappelleri J, Ming IC, Weiden P (1999). Antipsychotic-induced weight gain: A comprehensive research synthesis. American Journal of Psychiatry, 156, 1686-1696

Heo M, Gabriel KR (1998). A permutation test of association between configurations by means of the RV Coefficients. Communications in Statistics: Simulation and Computation, 27, 843-856

Moss A., Hall WJ, Cannom D, Daubert J, Higgins S, Kline H, Levine J, Saksensa S, Waldo A, Wilber D, Brown M, Heo M (1996). Improved Survival with an Implanted Defibrillator in Patients with Coronary Disease at High Risk for Ventricular Arrhythmias. The New England Journal of Medicine, 335, 1933 - 1940

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