Faculty Profile

Dr. Matthew K. Abramowitz, M.D.

Matthew K. Abramowitz, M.D.

Associate Professor, Department of Medicine (Nephrology)

Areas of Research: Abnormalities of physical function in chronic kidney disease, including skeletal muscle pathology, protein metabolism, and gait disturbances; sequelae and management of acid-base disorders; accelerated aging in CKD

Professional Interests

Matthew Abramowitz, M.D., M.S. completed his medical education at the Albert Einstein College of Medicine and internal medicine residency at Montefiore Medical Center, where he was a Chief Resident.  He remained at Einstein/Montefiore for nephrology fellowship and earned a Masters in Clinical Research through Einstein’s Clinical Research Training Program.  He is currently Associate Professor of Medicine at Einstein.  He is the recipient of a Career Development Award from the Einstein/Montefiore Institute for Clinical and Translational Research, a Carl Gottschalk Research Scholar Grant from the American Society of Nephrology, and a K23 Career Development Award from the National Institutes of Health.

Dr. Abramowitz’s research focuses on understanding the causes of impaired physical function and loss of mobility that are commonly experienced by patients with chronic kidney disease.   He is studying alterations in skeletal muscle physiology and exploring novel measures of functional capacity in this patient population.  

Selected Publications

Shah SN, Abramowitz M, Hostetter TH, Melamed ML. Serum bicarbonate levels and the progression of kidney disease: a cohort study.  American Journal of Kidney Diseases 2009 Aug;54(2):270-277

Alencar C, Abramowitz M, Parekh S, Braunshweig I, Jacobson M, Silverman L, Verma A. Atypical presentations of Sweet's syndrome in patients with MDS/AML receiving combinations of hypomethylating agents with histone deacetylase inhibitors. American Journal of Hematology 2009 Oct; 84(10):688-689

Abramowitz M, Muntner P, Coco M, Southern W, Lotwin I, Hostetter TH, Melamed ML. Serum alkaline phosphatase and phosphate and risk of mortality and hospitalization. Clinical Journal of the American Society of Nephrology 5: 1064-1071, 2010

Bauer C, Abramowitz M, Hostetter TH. Is angiotensin blockade indicated in the elderly? Nature Reviews Nephrology 2010 Jan; 6(1): 11-12

Abramowitz MK, Hostetter TH, Melamed ML. Association of serum bicarbonate levels with gait speed and quadriceps strength in older adults. American Journal of Kidney Diseases 58: 29-38, 2011

Skversky AL, Kumar J, Abramowitz MK, Kaskel FJ, Melamed ML. Association of glucocorticoid use and low 25-hydroxyvitamin D levels: results from the National Health and Nutrition Examination Survey (NHANES): 2001-2006. J Clin Endocrinol Metab 96:3838-3845, 2011

Turner J, Bauer C, Abramowitz MK, Melamed ML, Hostetter TH. Treatment of chronic kidney disease. Kidney Int 81: 351-362, 2012

Abramowitz MK, Hostetter TH, Melamed ML. Lower serum bicarbonate and a higher anion gap are associated with lower cardiorespiratory fitness in young adults. Kidney Int 81:1033-42, 2012

Abramowitz MK, Hostetter TH, Melamed ML. Serum anion gap, kidney function, and mortality in US adults. Kidney Int 82: 701-709, 2012

Abramowitz MK, Melamed ML, Bauer C, Raff AC, Hostetter TH. Effects of oral sodium bicarbonate in patients with CKD. Clinical Journal of the American Society of Nephrology 8:714-20, 2013

Chen W, Abramowitz MK. Treatment of Metabolic Acidosis in Patients with Chronic Kidney Disease. American Journal of Kidney Diseases 63: 311-317, 2014

Amodu A, Abramowitz MK. Dietary acid, age, and serum bicarbonate levels among adults in the United States. Clinical Journal of the American Society of Nephrology 8:2034-42, 2013

Chen W, Abramowitz MK. Metabolic acidosis and the progression of chronic kidney disease. BMC Nephrology 15:55, 2014  

Abramowitz MK. Acid-base balance and physical function. Clinical Journal of the American Society of Nephrology, 9:2030-2, 2014

Sharma D, Hawkins M, Abramowitz MK. Association of sarcopenia with eGFR and misclassification of obesity in adults with chronic kidney disease in the United States. Clinical Journal of the American Society of Nephrology, 9:2079-88, 2014

Chen W, Melamed ML, Abramowitz MK. Serum bicarbonate and bone mineral density in United States adults. American Journal of Kidney Diseases, 65:240-248, 2015

Huston HK, Abramowitz MK, Zhang Y, Greene T, Raphael KL. Net endogenous acid production and mortality in NHANES III. Nephrology, 20:209-15, 2015

Sarathy H, Pramanik V, Kahn J, Abramowitz MK, Meier K, Kishore P, Melamed ML. The effects of short-term vitamin D supplementation on glucose metabolism in dialysis patients: a systematic review and meta-analysis.  Int Urol Nephrol, 47:537-49, 2015

Patel R, Paredes W, Hall CB, Nader MA, Sapkota D, Folkert VW, Abramowitz MK. Variability in monthly serum bicarbonate measures in hemodialysis patients: a cohort study. BMC Nephrology, 16:214, 2015

Sarathy H, Henriquez G, Abramowitz MK, Kramer H, Rosas SE, Johns T, Kumar J, Skversky A, Kaskel FJ, Melamed ML. Abdominal Obesity, Race and Chronic Kidney Disease in Young Adults: Results from NHANES 1999-2010. PLOS One, 11(5): e0153588, 2016

Liang E, Rodriguez M, Mueller M, Abramowitz MK, Mokrzycki MH. Outcomes associated with a heparin-free hemodialysis protocol and review of the literature. Journal of Clinical Nephrology and Renal Care, 2:010, 2016

Chen W, Melamed ML, Hostetter TH, Bauer C, Raff AC, Almudevar AL, Lalonde A, Messing S, Abramowitz MK. Effect of Oral Sodium Bicarbonate on Fibroblast Growth Factor-23 in Patients with Chronic Kidney Disease: A Pilot Study. BMC Nephrology, 17:114, 2016

Abramowitz MK, Sharma D, Folkert VW. Hidden obesity in dialysis patients: clinical implications. Seminars in Dialysis, 29:391-395, 2016

Androga L, Sharma D, Amodu A, Abramowitz MK. Sarcopenia, obesity, and mortality in US adults with and without chronic kidney disease. Kidney International Reports, 2:201-211, 2017

Blanco I, Labitigan M, Abramowitz MK. The Association Between Anti-Nuclear Antibodies and Obesity is Likely Mediated by Abdominal Adiposity and Systemic Inflammation. Journal of Clinical & Cellular Immunology, 8:4, 2017

Abramowitz MK. HCO3 balance and prescription in ESRD. Journal of the American Society of Nephrology, 28:726-734, 2017

Abramowitz MK, Hall CB, Amodu A, Sharma D, Androga A, Hawkins M. Muscle mass, BMI, and mortality among adults in the United States: A population-based cohort study. PLOS One, 13(4): e0194697, 2018

Chen W, Anokhina V, Miller B, Dieudonne G; Abramowitz MK, Kashyap R, Yan C, Wu TT, Bentley KL, Bushinsky DA. Patients with Advanced Chronic Kidney Disease and Vascular Calcification Have a Large Hydrodynamic Radius of Secondary Calciprotein Particles. Nephrology Dialysis Transplantation, 34(6):992-1000, 2019

Scialla JJ, Brown L, Gurley S, Corcoran DL, Bain JR, Muehlbauer MJ, O’Neal SK, O’Connell T, Wolf M, Melamed ML, Hostetter TH, Abramowitz MK. Metabolic impact of base-loading in chronic kidney disease. Clinical Journal of the American Society of Nephrology, 13:1244-1246, 2018

Abramowitz MK. Metabolic Acidosis and Cardiovascular Disease Risk in CKD. Clinical Journal of the American Society of Nephrology, 13:1451-1452, 2018

Lee JA, Abramowitz MK, Kipperman N, Drzewiecki BA, Melamed ML, Stern JM. Exploring the Association of Asthma with Urinary Stone Disease: Results from the National Health and Nutrition Examination Survey 2007-2014. European Urology Focus, 2018 Aug 7 epub ahead of print

Abramowitz MK, Paredes W, Zhang K, Brightwell CR, Newsom JN, Kwon H, Custodio M, Buttar RS, Farooq H, Zaidi B, Pai R, Pessin JE, Hawkins M, Fry CS. Skeletal muscle fibrosis is associated with decreased muscle inflammation and weakness in patients with chronic kidney disease. American Journal of Physiology - Renal Physiology. 315(6):F1658-1669, 2018

Watts KL, Srivastava A, Lin W, Schoenfeld D, Abramowitz M, Stern JM: Baseline chronic kidney disease does not predict long-term renal functional decline after percutaneous nephrolithotomy. Urolithiasis, 2019 Feb 12, epub ahead of print

Tran J, Ayers E, Verghese J, Abramowitz MK. Gait abnormalities and the risk of falls in chronic kidney disease. Clinical Journal of the American Society of Nephrology, 14:983-993, 2019

Chen W, Eisenberg R, Mowrey WB, Wylie-Rosett J, Abramowitz MK, Bushinsky DA, Melamed ML. Association between dietary zinc intake and abdominal aortic calcification in US adults. Nephrology Dialysis Transplantation, 2019 Jul 11, Epub ahead of print

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Research Information