Medical Scientist Training Program (MSTP)

Student Publications

MSTP students graduating in the past five years published an average of 4.6 papers per student, 2.6 first author papers per student. Thus, the students were highly productive in their thesis research. 48% of these papers involved collaborations between the laboratories of two or more Einstein faculty members. This demonstrates the highly collaborative nature of the Einstein faculty.

Recent publications by MSTP students:

publicationsFirestone RS, Schramm VL. The Transition-State Structure for Human MAT2A from Isotope Effects. J Am Chem Soc. 2017 Oct 4; 139(39):13754-13760.

publicationsOsterbur Badhey ML, Bertalovitz AC, McDonald TV. Express with caution: Epitope tags and cDNA variants effects on hERG channel trafficking, half-life and function. J Cardiovasc Electrophysiol. 2017 Sep; 28(9):1070-1082.

publicationsKratschmer C, Levy M. Effect of Chemical Modifications on Aptamer Stability in Serum. Nucleic Acid Ther. 2017 Sep 25. [Epub ahead of print].

publications Tewari A, Fremont R, Khodakhah K. It's not just the basal ganglia: Cerebellum as a target for dystonia therapeutics. Mov Disord. 2017 Aug 26. doi: 10.1002/mds.27123. [Epub ahead of print].

publications Saied-Santiago K, Townley RA, Attonito JD, da Cunha DS, Diaz-Balzac CA, Tecle E, Bülow HE. Coordination of Heparan Sulfate Proteoglycans with Wnt Signaling To Control Cellular Migrations and Positioning in Caenorhabditis elegans. Genetics. 2017 Aug; 206(4):1951-1967.

publicationsBowen A, Wear M, Casadevall A. Antibody-mediated Catalysis in Infection and Immunity. Infect Immun. 2017 Aug 18; 85(9). pii: e00202-17.

publicationsWeiss CN, Ito K. A Macro View of MicroRNAs: The Discovery of MicroRNAs and Their Role in Hematopoiesis and Hematologic Disease. Int Rev Cell Mol Biol. 2017; 334:99-175.

publicationsYang H, Sternson SM. Raphe Circuits on the Menu. Cell. 2017 Jul 27;170(3):409-410.

publicationsGlass LN, Swapna G, Chavadi SS, Tufariello JM, Mi K, Drumm JE, Lam TT, Zhu G, Zhan C, Vilchéze C, Arcos J, Chen Y, Bi L, Mehta S, Porcelli SA, Almo SC, Yeh SR, Jacobs WR Jr, Torrelles JB, Chan J. Mycobacterium tuberculosis universal stress protein Rv2623 interacts with the putative ATP binding cassette (APC) transporter Rv1747 to regulate mycobacterial growth. PLoS Pathog. 2017 Jul 28; 13(7):e1006515.

publications Garner TP, Lopez A, Reyna DE, Spitz AZ, Gavathiotis E. Progress in targeting the BCL-2 family of proteins. Curr Opin Chem Biol. 2017 Jul 20; 39:133-142.

publications Santos-Ledo A, Garcia-Macia M, Campbell PD, Gronska M, Marlow FL. Kinesin-1 promotes chondrocyte maintenance during skeletal morphogenesis. PLoS Genet.2017 Jul 17; 13(7):e1006918.

publicationsWilson TJ, Gray MJ, Van Klinken JW, Kaczmarczyk M, Foxe JJ. Macronutrient composition of a morning meal and the maintenance of attention throughout the morning. Nutr Neurosci. 2017 Jul 17:1-15.

publicationsSnow M, Coen-Cagli R, Schwartz O. Adaptation in the visual cortex: a case for probing neuronal populations with natural stimuli. F1000Res. 2017 Jul 27; 6:1246.

publications Yang M, Arai A, Udagawa N, Hiraga T, Lijuan Z, Ito S, Komori T, Moriishi T, Matsuo K, Shimoda K, Zahalka AH, Kobayashi Y, Takahashi N, Mizoguchi T. Osteogenic Factor Runx2 Marks a Subset of Leptin Receptor-Positive Cells that Sit Atop the Bone Marrow Stromal Cell Hierarchy. Sci Rep. 2017 Jul 10; 7(1):4928.

publicationsJiang JM, Seng EK, Zimmerman ME, Sliwinski M, Kim M, Lipton RB. Evaluation of the Reliability, Validity, and Predictive Validity of the Subscales of the Perceived Stress Scale in Older Adults. J Alzheimers Dis. 2017; 59(3):987-996.

publicationsStock AD, Gelb S, Pasternak O, Ben-Zvi A, Putterman C. The Blood Brain Barrier and Neuropsychiatric Lupus: New perspectives in light of advances in understanding the neuroimmune interface. Autoimmun Rev. 2017 Jun; 16(6):612-619.

publicationsKeller CJ, Davidesco I, Megevand P, Lado FA, Malach R, Mehta AD. Tuning face perception with electrical stimulation of the fusiform gyrus. Hum Brain Mapp. 2017 Jun; 38(6):2830-2842.

publicationsLeung E, Xue A, Wang Y, Rougerie P, Sharma VP, Eddy R, Cox D, Condeelis J. Blood vessel endothelium-directed tumor cell streaming in breast tumors requires the HGF/C-Met signaling pathway. Oncogene. 2017 May 11; 36(19):2680-2692.

publications Han B, Polonais V, Sugi T, Yakubu R, Takvorian PM, Cali A, Maier K, Long M, Levy M, Tanowitz HB, Pan G, Delbac F, Zhou Z, Weiss LM. The role of microsporidian polar tube protein 4 (PTP4) in host cell infection. PLoS Pathog. 2017 Apr 20; 13(4):e1006341.

publicationsYakubu RR, Silmon de Monerri NC, Nieves E, Kim K, Weiss LM. Comparative Monomethylarginine Proteomics Suggests that PRMT1 is a Significant Contributor to Arginine Monomethylation in Toxoplasma gondii. Mol Cell Proteomics. 2017 Apr; 16(4):567-580.

publications Andreyeva EN, Bernardo TJ, Kolesnikova TD, Lu X, Yarinich LA, Bartholdy BA, Guo X, Posukh OV, Healton S, Willcockson MA, Pindyurin AV, Zhimulev IF, Skoultchi AI, Fyodorov DV. Regulatory functions and chromatin loading dynamics of linker histone H1 during endoreplication in Drosophila. Genes Dev. 2017 Mar 15; 31(6):603-616.

publicationsKerantzas CA, Jacobs WR Jr. Origins of Combination Therapy for Tuberculosis: Lessons for Future Antimicrobial Development and Application. MBio. 2017 Mar 14; 8(2). pii: e01586-16.

publicationsWheat JC, Steidl U. ETO2-GLIS2: A Chimeric Transcription Factor Drives Leukemogenesis through a Neomorphic Transcription Network. Cancer Cell. 2017 Mar 13; 31(3):307-308.

publicationsStanley RF, Piszczatowski RT, Bartholdy B, Mitchell K, McKimpson WM, Narayanagari S, Walter D, Todorova TI, Hirsch C, Makishima H, Will B, McMahon C, Gritsman K, Maciejewski JP, Kitsis RN, Steidl U. A myeloid tumor suppressor role for NOL3. J Exp Med. 2017 Mar 6; 214(3):753-771.

publicationsFirestone RS, Cameron SA, Karp JM, Arcus VL, Schramm VL. Heat Capacity Changes for Transition-State Analogue Binding and Catalysis with Human 5'-Methylthioadenosine Phosphorylase. ACS Chem Biol. 2017 Feb 17; 12(2):464-473.

publicationsFremont R, Tewari A, Angueyra C, Khodakhah K. A role for cerebellum in the hereditary dystonia DYT1. Elife. 2017 Feb 15; 6. pii: e22775.

publicationsKarp JM, Sparks S, Cowburn D. Effects of FGFR2 kinase activation loop dynamics on catalytic activity. PLoS Comput Biol. 2017 Feb 2; 13(2):e1005360.

publicationsKhor S, Cai D. Hypothalamic and inflammatory basis of hypertension. Clin Sci (Lond). 2017 Feb 1; 131(3):211-223.

publications Cheng H, Janakiram M, Borczuk A, Lin J, Qiu W, Liu H, Chinai J, Halmos B, Perez-Soler R, Zang X. HHLA2, a new immune checkpoint member of the B7 family, is widely expressed in human lung cancer and associated with EGFR mutational status. Clin Cancer Res. 2017 Feb 1;23(3):825-832.

publications Harony-Nicolas H, Kay M, Hoffmann JD, Klein ME, Bozdagi-Gunal O, Riad M, Daskalakis NP, Sonar S, Castillo PE, Hof PR, Shapiro ML, Baxter MG, Wagner S, Buxbaum JD. Oxytocin improves behavioral and electrophysiological deficits in a novel Shank3-deficient rat. Elife. 2017 Jan 31;6. pii: e18904. doi: 10.7554/eLife.18904.

publicationsWijetunga NA, Johnston AD, Maekawa R, Delahaye F, Ulahannan N, Kim K, Greally JM. SMITE: an R/Bioconductor package that identifies network modules by integrating genomic and epigenomic information. BMC Bioinformatics. 2017 Jan 18; 18(1):41.

publicationsBowen A, Wear MP, Cordero R, Oscarson S, Casadevall A. A monoclonal antibody to Cryptococcus neoformans glucuronoxylomannan manifests hydrolytic activity for both peptides and polysaccharides. J Biol Chem. 2017 Jan 13; 292(2):417-434.

publications Tomita T, Sugi T, Yakubu R, Tu V, Ma Y, Weiss LM. Making Home Sweet and Sturdy: Toxoplasma gondii ppGalNAc-Ts Glycosylate in Hierarchical Order and Confer Cyst Wall Rigidity. MBio. 2017 Jan 10;8(1). pii: e02048-16. doi: 10.1128/mBio.02048-16.

publications Kaplan RC, Strizich G, Aneke-Nash C, Dominguez-Islas C, Bůžková P, Strickler H, Rohan T, Pollak M, Kuller L, Kizer JR, Cappola A, Li CI, Psaty BM, Newman A. Insulinlike growth factor binding protein-1 and ghrelin predict health outcomes among older adults: CHS cohort. J Clin Endocrinol Metab. 2017 Jan 1; 102(1):267-278.

publications Pignatelli J, Bravo-Cordero JJ, Roh-Johnson M, Gandhi SJ, Wang Y, Chen X, Eddy RJ, Xue A, Singer RH, Hodgson L, Oktay MH, Condeelis JS. Macrophage-dependent tumor cell transendothelial migration is mediated by Notch1/Mena(INV)-initiated invadopodium formation. Sci Rep. 2016 Nov 30;6:37874.

publications Vera M, Biswas J, Senecal A, Singer RH, Park HY. Single-Cell and Single-Molecule Analysis of Gene Expression Regulation. Annu Rev Genet. 2016 Nov 23; 50:267-291.

publicationsCao LL, Riascos-Bernal DF, Chinnasamy P, Dunaway CM, Hou R, Pujato MA, O'Rourke BP, Miskolci V, Guo L, Hodgson L, Fiser A, Sibinga NE. Control of mitochondrial function and cell growth by the atypical cadherin Fat1. Nature. 2016 Nov 24; 539(7630):575-578.

publicationsWeidmann MD, Surve CR, Eddy RJ, Chen X, Gertler FB, Sharma VP, Condeelis JS. Mena(INV) dysregulates cortactin phosphorylation to promote invadopodium maturation. Sci Rep. 2016 Nov 8; 6:36142.

publications Mayer O, Jain P, Weisbrod T, Biro D, Ho L, Jacobs-Sera D, Hatfull GF, Jacobs WR Jr. Fluorescent reporter DS6A mycobacteriophages reveal unique variations in infectability and phage production in mycobacteria. J Bacteriol. 2016 Nov 4; 198(23):3220-3232.

publications Younts TJ, Monday HR, Dudok B, Klein ME, Jordan BA, Katona I, Castillo PE. Presynaptic Protein Synthesis Is Required for Long-Term Plasticity of GABA Release. Neuron. 2016 Oct 19; 92(2):479-492.

publications Heo HJ, Tozour JN, Delahaye F, Zhao Y, Cui L, Barzilai N, Einstein FH. Advanced aging phenotype is revealed by epigenetic modifications in rat liver after in utero malnutrition. Aging Cell. 2016 Oct; 15(5):964-72.

publicationsWijetunga NA, Pascual M, Tozour J, Delahaye F, Alani M, Adeyeye M, Wolkoff AW, Verma A, Greally JM. A pre-neoplastic epigenetic field defect in HCV-infected liver at transcription factor binding sites and polycomb targets. Oncogene. 2016 Oct 10. doi: 10.1038/onc.2016.340.

publicationsAguilar JL, Varshney AK, Pechuan X, Dutta K, Nosanchuk JD, Fries BC. Monoclonal antibodies protect from Staphylococcal Enterotoxin K (SEK) induced toxic shock and sepsis by USA300 Staphylococcus aureus. Virulence. 2016 Oct 7:0.

publicationsSnow M, Coen-Cagli R, Schwartz O. Specificity and timescales of cortical adaptation as inferences about natural movie statistics. J Vis. 2016 Oct 1;16(13). doi: 10.1167/16.13.1.

publications Mani KM, Savage T, Basu I, Scandiuzzi L, Asp P, Guha C. Epigenetic Priming and High-Dose Radiation for Enhanced Immune Response in Pancreatic Cancer. Int J Radiat Oncol Biol Phys. 2016 Oct 1; 96(2S):S86-S87.

publications Shakkottai VG, Batla A, Bhatia K, Dauer WT, Dresel C, Niethammer M, Eidelberg D, Raike RS, Smith Y, Jinnah HA, Hess EJ, Meunier S, Hallett M, Fremont R, Khodakhah K, LeDoux MS, Popa T, Gallea C, Lehericy S, Bostan AC, Strick PL. Current Opinions and Areas of Consensus on the Role of the Cerebellum in Dystonia. Cerebellum. 2016 Oct 12. Review.

publications Sawicka K*, Pyronneau A*, Chao M, Bennett MV, Zukin RS. Elevated ERK/p90 ribosomal S6 kinase activity underlies audiogenic seizure susceptibility in fragile X mice. Proc Natl Acad Sci U S A. 2016 Sep 23. pii: 201610812. [Epub ahead of print]. *Contributed equally.

publicationsBowen A, Casadevall A. Revisiting the immunoglobulin intramolecular signaling hypothesis. Trends Immunol.2016 Nov; 37(11):721-723.

publications Wen J, Stock AD, Chalmers SA, Putterman C. The role of B cells and autoantibodies in neuropsychiatric lupus. Autoimmun Rev. 2016 Sep; 15(9):890-5.

publicationsWijetunga NA, Belbin TJ, Burk RD, Whitney K, Abadi M, Greally JM, Einstein MH, Schlecht NF. Novel epigenetic changes in CDKN2A are associated with progression of cervical intraepithelial neoplasia. Gynecol Oncol. 2016 Sep; 142(3):566-73.

publicationsWijetunga NA, Ben-Dayan M, Tozour J, Burk RD, Schlecht NF, Einstein MH, Greally JM. A polycomb-mediated epigenetic field defect precedes invasive cervical carcinoma. Oncotarget. 2016 Sep 20; 7(38):62133-62143.

publicationsDíaz-Balzac CA, Rahman M, Lázaro-Peña MI, Martin Hernandez LA, Salzberg Y, Aguirre-Chen C, Kaprielian Z, Bülow HE. Muscle- and skin-derived cues jointly orchestrate patterning of somatosensory dendrites. Curr Biol. 2016 Sep 12; 26(17):2379-87

publications Kravchick DO, Karpova A, Hrdinka M, Lopez-Rojas J, Iacobas S, Carbonell AU, Iacobas DA, Kreutz MR, Jordan BA. Synaptonuclear messenger PRR7 inhibits c-Jun ubiquitination and regulates NMDA-mediated excitotoxicity. EMBO J. 2016 Sep 1; 35(17):1923-34.

publications Sato H, Wheat JC, Steidl U, Ito K. DNMT3A and TET2 in the pre-leukemic phase of hematopoietic disorders. Front Oncol. 2016 Aug 22; 6:187.

publicationsKoirala P, Roth ME, Gill J, Chinai JM, Ewart MR, Piperdi S, Geller DS, Hoang BH, Fatakhova YV, Ghorpade M, Zang X, Gorlick R. HHLA2, a member of the B7 family, is expressed in human osteosarcoma and is associated with metastases and worse survival. Sci Rep. 2016 Aug 17;6:31154.

publications Riascos-Bernal DF, Chinnasamy P, Cao LL, Dunaway CM, Valenta T, Basler K, Sibinga NE. β-Catenin C-terminal signals suppress p53 and are essential for artery formation. Nat Commun. 2016 Aug 8; 7:12389.

publications Eslami V, Katz MJ, White RS, Sundermann E, Jiang JM, Ezzati A, Lipton RB. Pain intensity and pain interference in older adults: Role of gender, obesity and high-sensitivity C-reactive protein. Gerontology. 2017; 63(1):3-12.

publications Geller DS, Morris J, Revskaya E, Kahn M, Zhang W, Piperdi S, Park A, Koirala P, Guzik H, Hall C, Hoang B, Yang R, Roth M, Gill J, Gorlick R, Dadachova E. Targeted therapy of osteosarcoma with radiolabeled monoclonal antibody to an insulin-like growth factor-2 receptor (IGF2R). Nucl Med Biol. 2016 Jul 30; 43(12):812-817.

publicationsKoirala P, Roth ME, Gill J, Piperdi S, Chinai JM, Geller DS, Hoang BH, Park A, Fremed MA, Zang X, Gorlick R. Immune infiltration and PD-L1 expression in the tumor microenvironment are prognostic in osteosarcoma. Sci Rep. 2016 Jul 26; 6:30093.

publicationsPiszczatowski RT, Lents NH. Regulation of the CCN genes by vitamin D: A possible adjuvant therapy in the treatment of cancer and fibrosis. Cell Signal. 2016 Jul 25; 28(10):1604-1613.

publications Picarda E, Ohaegbulam KC, Zang X. Molecular Pathways: Targeting B7-H3 (CD276) for Human Cancer Immunotherapy. Clin Cancer Res. 2016 Jul 15; 22(14):3425-31.

publications Choi CH, Schoenfeld BP, Bell AJ, Hinchey J, Rosenfelt C, Gertner MJ, Campbell SR, Emerson D, Hinchey P, Kollaros M, Ferrick NJ, Chambers DB, Langer S, Sust S, Malik A, Terlizzi AM, Liebelt DA, Ferreiro D, Sharma A, Koenigsberg E, Choi RJ, Louneva N, Arnold SE, Featherstone RE, Siegel SJ, Zukin RS, McDonald TV, Bolduc FV, Jongens TA, McBride SM. Multiple drug treatments That increase cAMP signaling restore long-term memory and aberrant signaling in Fragile X Syndrome models. Front Behav Neurosci. 2016 Jun 30; 10:136.

publicationsChiang SP, Cabrera RM, Segall JE. Tumor cell intravasation. A review in the theme: Cell and molecular processes in cancer metastasis. Am J Physiol Cell Physiol. 2016 Jul 1; 311(1):C1-C14.

publicationsArora A, Deniskin R, Sosa Y, Nishtala SN, Henrich PP, Kumar TR, Fidock DA, Akabas MH. Substrate and inhibitor specificity of the Plasmodium berghei Equilibrative Nucleoside Transporter Type 1 (PbENT1). Mol Pharmacol. 2016 Jun; 89(6):678-85.

publicationsTow A, Holtzer R, Wang C, Sharan A, Kim SJ, Gladstein A, Blum Y, Verghese J. Cognitive Reserve and Postoperative Delirium in Older Adults. J Am Geriatr Soc. 2016 Jun; 64(6):1341-6.

publicationsKaufman OH, Marlow FL. Methods to study maternal regulation of germ cell specification in zebrafish. Methods Cell Biol. 2016; 134:1-32.

publications Wen J, Chen C, Stock A, Doerner J, Gulinello M, Putterman C. Intracerebroventricular administration of TNF-like weak inducer of apoptosis induces depression-like behavior and cognitive dysfunction in non-autoimmune mice. Brain Behav Immun. 2016 May; 54:27-37.

publications Raveh B*, Karp JM*, Sparks S*, Dutta K, Rout MP, Sali A, Cowburn D. Slide-and-exchange mechanism for rapid and selective transport through the nuclear pore complex. Proc Natl Acad Sci U S A. 2016 May 3; 113(18):E2489-97. *contributed equally

publications Maier KE, Jangra RK, Shieh KR, Cureton DK, Xiao H, Snapp EL, Whelan SP, Chandran K, Levy M. A New Transferrin Receptor Aptamer Inhibits New World Hemorrhagic Fever Mammarenavirus Entry. Mol Ther Nucleic Acids. 2016 May 24; 5:e321.

publications Picarda E, Ohaegbulam KC, Zang X. Molecular Pathways: Targeting B7-H3 (CD276) for Human Cancer Immunotherapy. Clin Cancer Res. 2016 Jul 15; 22(14):3425-31.

publicationsKeller CJ, Chen C, Lado FA, Khodakhah K. The Limited Utility of Multiunit Data in Differentiating Neuronal Population Activity. PLoS One. 2016 Apr 25; 11(4):e0153154.

publications Wen J, Doerner J, Chalmers S, Stock A, Wang H, Gullinello M, Shlomchik MJ, Putterman C. B cell and/or autoantibody deficiency do not prevent neuropsychiatric disease in murine systemic lupus erythematosus. J Neuroinflammation. 2016 Apr 7; 13(1):73.

publicationsStanley RF, Steidl U. Molecular Mechanism of Mutant CALR-Mediated Transformation. Cancer Discov. 2016 Apr; 6(4):344-6.

publicationsDeniskin R, Frame IJ, Sosa Y, Akabas MH. Targeting the Plasmodium vivax equilibrative nucleoside transporter 1 (PvENT1) for antimalarial drug development. Int J Parasitol Drugs Drug Resist. 2016; 6(1):1-11.

publications Ndungo E, Herbert AS, Raaben M, Obernosterer G, Biswas R, Miller EH, Wirchnianski AS, Carette JE, Brummelkamp TR, Whelan SP, Dye JM, Chandran K. A Single Residue in Ebola Virus Receptor NPC1 Influences Cellular Host Range in Reptiles. mSphere. 2016 Mar 30; 1(2). pii: e00007-16.

publicationsStanley RF, Steidl U. Ectopic DNMT3B expression delays leukemogenesis. Blood. 2016 Mar 24; 127(12):1525-6.

publicationsDíaz-Balzac CA, Lázaro-Peña MI, Vázquez-Figueroa LD, Díaz-Balzac RJ, García-Arrarás JE. Holothurian Nervous System Diversity Revealed by Neuroanatomical Analysis. PLoS One. 2016 Mar 17; 11(3):e0151129.

publications Sidney J, Schloss J, Moore C, Lindvall M, Wriston A, Hunt DF, Shabanowitz J, DiLorenzo TP, Sette A. Characterization of the peptide binding specificity of the HLA class I alleles B*38:01 and B*39:06. Immunogenetics. 2016 Mar; 68(3):231-6.

publicationsShemesh A, Taub CC. Inferolateral ST elevation in Boerhaave syndrome. Am J Med. 2016 Mar; 129(3):e27-8.

publications Fang FC, Bowen A, Casadevall A. NIH peer review percentile scores are poorly predictive of grant productivity. Elife. 2016 Feb 16; 5. pii: e13323. doi: 10.7554/eLife.13323.

publicationsJanda A, Bowen A, Greenspan NS, Casadevall A. Ig constant region effects on variable region structure and function. Front Microbiol. 2016 Feb 4; 7:22.

publicationsKlein ME, Monday H, Jordan BA. Proteostasis and RNA binding proteins in synaptic plasticity and in the pathogenesis of neuropsychiatric disorders. Neural Plast. 2016; 2016:3857934.

publications Babad J, Ali R, Schloss J, DiLorenzo TP. An HLA-transgenic mouse model of Type 1 diabetes that incorporates the reduced but not abolished thymic insulin expression seen in patients. J Diabetes Res.2016; 2016:7959060. doi: 10.1155/2016/7959060.

publications Xie Q, McGreal R, Harris R, Gao CY, Liu W, Reneker LW, Musil LS, Cvekl A. Regulation of c-Maf and αA-crystallin in ocular lens by FGF signaling. J Biol Chem. 2016 Feb 19; 291(8):3947-58.

publicationsAneke-Nash CS, Dominguez-Islas C, Bůžková P, Qi Q, Xue X, Pollak M, Strickler HD, Kaplan RC. Agreement between circulating IGF-I, IGFBP-1 and IGFBP-3 levels measured by current assays versus unavailable assays previously used in epidemiological studies. Growth Horm IGF Res. 2016 Feb; 26:11-6.

publications Tufariello JM, Chapman JR, Kerantzas CA, Wong KW, Vilchèze C, Jones CM, Cole LE, Tinaztepe E, Thompson V, Fenyö D, Niederweis M, Ueberheide B, Philips JA, Jacobs WR Jr. Separable roles for Mycobacterium tuberculosis ESX-3 effectors in iron acquisition and virulence. Proc Natl Acad Sci U S A. 2016 Jan 19; 113(3):E348-57.

publicationsUchime O, Dai Z, Biris N, Lee D, Sidhu SS, Li S, Lai JR, Gavathiotis E. Synthetic Antibodies Inhibit Bcl-2-associated X Protein (BAX) through Blockade of the N-terminal Activation Site. J Biol Chem. 2016 Jan 1; 291(1):89-102.

publications Martinez-Lopez N, Garcia-Macia M, Sahu S, Athonvarangkul D, Liebling E, Merlo P, Cecconi F, Schwartz GJ, Singh R. Autophagy in the CNS and Periphery Coordinate Lipophagy and Lipolysis in the Brown Adipose Tissue and Liver. Cell Metab. 2016 Jan 12; 23(1):113-27.

publications Ng M, Ndungo E, Kaczmarek ME, Herbert AS, Binger T, Kuehne AI, Jangra RK, Hawkins JA, Gifford RJ, Biswas R, Demogines A, James RM, Yu M, Brummelkamp TR, Drosten C, Wang LF, Kuhn JH, Müller MA, Dye JM, Sawyer SL, Chandran K. Filovirus receptor NPC1 contributes to species-specific patterns of ebolavirus susceptibility in bats. Elife.2015 Dec 23; 4. pii: e11785. doi: 10.7554/eLife.11785.

publicationsLoPiccolo J, Kim SJ, Shi Y, Wu B, Wu H, Chait BT, Singer RH, Sali A, Brenowitz M, Bresnick AR, Backer JM. Assembly and Molecular Architecture of the Phosphoinositide 3-Kinase p85α Homodimer. J Biol Chem. 2015 Dec 18; 290(51):30390-405.

publications Nadel J, Athanasiadou R, Lemetre C, Wijetunga NA, Ó Broin P, Sato H, Zhang Z, Jeddeloh J, Montagna C, Golden A, Seoighe C, Greally JM. RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships. Epigenetics Chromatin.2015 Nov 16; 8:46.

publications Tufariello JM, Kerantzas CA, Vilchèze C, Calder RB, Nordberg EK, Fischer JA, Hartman TE, Yang E, Driscoll T, Cole LE, Sebra R, Maqbool SB, Wattam AR, Jacobs WR Jr. The Complete Genome Sequence of the Emerging Pathogen Mycobacterium haemophilum Explains Its Unique Culture Requirements. MBio. 2015 Nov 17; 6(6). pii: e01313-15.

publications Silmon de Monerri NC, Yakubu RR, Chen AL, Bradley PJ, Nieves E, Weiss LM, Kim K. The Ubiquitin Proteome of Toxoplasma gondii Reveals Roles for Protein Ubiquitination in Cell-Cycle Transitions. Cell Host Microbe. 2015 Nov 11; 18(5):621-33.

publicationsBowen A, Casadevall A. Reply to Fiscella: The phases of biomedical research should be studied to optimize health outcomes. Proc Natl Acad Sci U S A. 2015 Nov 24; 112(47):E6413.

publicationsStock AD, Wen J, Doerner J, Herlitz LC, Gulinello M, Putterman C. Neuropsychiatric systemic lupus erythematosus persists despite attenuation of systemic disease in MRL/lpr mice. J Neuroinflammation. 2015 Nov 6; 12(1):205.

publicationsOkoye-Okafor UC, Bartholdy B, Cartier J, Gao EN, Pietrak B, Rendina AR, Rominger C, Quinn C, Smallwood A, Wiggall KJ, Reif AJ, Schmidt SJ, Qi H, Zhao H, Joberty G, Faelth-Savitski M, Bantscheff M, Drewes G, Duraiswami C, Brady P, Groy A, Narayanagari SR, Antony-Debre I, Mitchell K, Wang HR, Kao YR, Christopeit M, Carvajal L, Barreyro L, Paietta E, Makishima H, Will B, Concha N, Adams ND, Schwartz B, McCabe MT, Maciejewski J, Verma A, Steidl U. New IDH1 mutant inhibitors for treatment of acute myeloid leukemia. Nat Chem Biol. 2015 Nov; 11(11):878-86.

publicationsCampbell PD, Heim AE, Smith MZ, Marlow FL. Kinesin-1 interacts with Bucky ball to form germ cells and is required to pattern the zebrafish body axis. Development. 2015 Sep 1; 142(17):2996-3008.

publicationsBowen A, Casadevall A. Increasing disparities between resource inputs and outcomes, as measured by certain health deliverables, in biomedical research. Proc Natl Acad Sci U S A. 2015 Sep 8; 112(36):11335-40.

publications Nabet B, Ó Broin P, Reyes JM, Shieh K, Lin CY, Will CM, Popovic R, Ezponda T, Bradner JE, Golden AA, Licht JD. Deregulation of the Ras-Erk Signaling Axis Modulates the Enhancer Landscape. Cell Rep. 2015 Aug 25; 12(8):1300-1313.

publications Rhee DB, Croken MM, Shieh KR, Sullivan J, Micklem G, Kim K, Golden A. toxoMine: an integrated omics data warehouse for Toxoplasma gondii systems biology research. Database (Oxford). 2015 Jun 30; pii: bav066. doi: 10.1093/database/bav066.

publicationsFremont R, Tewari A, Khodakhah K. Aberrant Purkinje cell activity is the cause of dystonia in a shRNA-based mouse model of Rapid Onset Dystonia-Parkinsonism. Neurobiol Dis. 2015 Jun 17; 82:200-212.

publicationsSmith C, Pechuan X, Puzio RS, Biro D, Bergman A. Potential unsatisfiability of cyclic constraints on stochastic biological networks biases selection towards hierarchical architectures. J R Soc Interface. 2015 Jul 6;12(108). pii: 20150179. doi: 10.1098/rsif.2015.0179.

publicationsTindi JO, Chávez AE, Cvejic S, Calvo-Ochoa E, Castillo PE, Jordan BA. ANKS1B Gene Product AIDA-1 Controls Hippocampal Synaptic Transmission by Regulating GluN2B Subunit Localization. J Neurosci. 2015 Jun 17; 35(24):8986-96.

publicationsDíaz-Balzac CA, Lázaro-Peña MI, Ramos-Ortiz GA, Bülow HE. The Adhesion Molecule KAL-1/anosmin-1 Regulates Neurite Branching through a SAX-7/L1CAM-EGL-15/FGFR Receptor Complex. Cell Rep. 2015 Jun 9; 11(9):1377-84.

publications Wen J, Doerner J, Weidenheim K, Xia Y, Stock A, Michaelson JS, Baruch K, Deczkowska A, Gulinello M, Schwartz M, Burkly LC, Putterman C. TNF-like weak inducer of apoptosis promotes blood brain barrier disruption and increases neuronal cell death in MRL/lpr mice. J Autoimmun. 2015 Jun; 60:40-50.

publicationsAneke-Nash CS, Parrinello CM, Rajpathak SN, Rohan TE, Strotmeyer ES, Kritchevsky SB, Psaty BM, Bůžková P, Kizer JR, Newman AB, Strickler HD, Kaplan RC. Changes in insulin-like growth factor-I and its binding proteins are associated with diabetes mellitus in older adults. J Am Geriatr Soc. 2015 May; 63(5):902-9.

publicationsNicholas MP, Berger F, Rao L, Brenner S, Cho C, Gennerich A. Cytoplasmic dynein regulates its attachment to microtubules via nucleotide state-switched mechanosensing at multiple AAA domains. Proc Natl Acad Sci U S A. 2015 May 19; 112(20):6371-6.

publications Janakiram M, Chinai J, Fineberg S, Fiser A, Montagna C, Medaverepu R, Castano E, Jeon H, Ohaegbulam KC, Zhao R, Zhao A, Almo S, Sparano JA, Zang X. Expression, clinical significance, and receptor identification of the newest B7 family member HHLA2 protein. Clin Cancer Res. 2015 May 15; 21(10):2359-66.

publicationsJanda A, Eryilmaz E, Nakouzi A, Pohl MA, Bowen A, Casadevall A. Variable region identical IgA and IgE to Cryptococcus neoformans capsular polysaccharide manifest specificity differences. J Biol Chem. 2015 May 8; 290(19):12090-100.

publications Xiong XD, Jung HJ, Gombar S, Park JY, Zhang CL, Zheng H, Ruan J, Li JB, Kaeberlein M, Kennedy BK, Zhou Z, Liu X, Suh Y. MicroRNA transcriptome analysis identifies miR-365 as a novel negative regulator of cell proliferation in Zmpste24-deficient mouse embryonic fibroblasts. Mutat Res. 2015 Apr 24; 777:69-78.

publications  Frame IJ*, Deniskin R*, Arora A, Akabas MH. Purine import into malaria parasites as a target for antimalarial drug development. Ann N Y Acad Sci. 2015 Apr; 1342:19-28. *Contributed equally.

publications Wu B, Miskolci V, Sato H, Tutucci E, Kenworthy CA, Donnelly SK, Yoon YJ, Cox D, Singer RH, Hodgson L. Synonymous modification results in high-fidelity gene expression of repetitive protein and nucleotide sequences. Genes Dev. 2015 Apr 15; 29(8):876-86.

publications Martinez-Lopez N, Athonvarangkul D, Singh R. Autophagy and aging. Adv Exp Med Biol. 2015; 847:73-87.

publicationsPark C, Suh Y, Cuervo AM. Regulated degradation of Chk1 by chaperone-mediated autophagy in response to DNA damage. Nat Commun. 2015 Apr 16; 6:6823.

publications Gray MJ, Frey HP, Wilson TJ, Foxe JJ. Oscillatory Recruitment of Bilateral Visual Cortex during Spatial Attention to Competing Rhythmic Inputs. J Neurosci. 2015 Apr 8; 35(14):5489-503.

publicationsSchneider JL, Villarroya J, Diaz-Carretero A, Patel B, Urbanska AM, Thi MM, Villarroya F, Santambrogio L, Cuervo AM. Loss of hepatic chaperone-mediated autophagy accelerates proteostasis failure in aging. Aging Cell. 2015 Apr; 14(2):249-64.

publications Mukherjee G, Chaparro RJ, Schloss J, Smith C, Bando CD, DiLorenzo TP. Glucagon-reactive Islet-infiltrating CD8 T Cells in NOD Mice. Immunology. 2015 Apr; 144(4):631-40.

publicationsCampbell PD, Chao JA, Singer RH, Marlow FL. Dynamic visualization of transcription and RNA subcellular localization in zebrafish. Development. 2015 Apr 1; 142(7):1368-74.

publicationsFrame IJ*, Deniskin R*, Rinderspacher A, Katz F, Deng SX, Moir RD, Adjalley SH, Coburn-Flynn O, Fidock DA, Willis IM, Landry DW, Akabas MH. Yeast-Based High-Throughput Screen Identifies Plasmodium falciparum Equilibrative Nucleoside Transporter 1 Inhibitors That Kill Malaria Parasites. ACS Chem Biol. 2015 Mar 20; 10(3):775-83. (*Contributed equally).

publicationsKlein ME, Castillo PE, Jordan BA. Coordination between Translation and Degradation Regulates Inducibility of mGluR-LTD. Cell Rep. 2015 Mar 3. pii: S2211-1247(15)00166-7.

publications Ramos MP, Wijetunga NA, McLellan AS, Suzuki M, Greally JM. DNA demethylation by 5-aza-2'-deoxycytidine is imprinted, targeted to euchromatin, and has limited transcriptional consequences. Epigenetics Chromatin. 2015 Mar 17; 8:11.

publications Salamon RS, Dbouk HA, Collado D, Lopiccolo J, Bresnick AR, Backer JM. Identification of the Rab5 Binding Site in p110β: Assays for PI3Kβ Binding to Rab5. Methods Mol Biol. 2015; 1298:271-81.

publicationsWeiss CN, Ito K. DNA Damage: A Sensible Mediator of the Differentiation Decision in Hematopoietic Stem Cells and in Leukemia. Int J Mol Sci. 2015 Mar 17; 16(3):6183-6201.

publicationsSanchez-Casalongue ME, Lee J, Diamond A, Shuldiner S, Moir RD, Willis IM. Differential Phosphorylation of a Regulatory Subunit of Protein Kinase CK2 by TOR Complex 1 Signaling and the Cdc-like Kinase Kns1. J Biol Chem. 2015 Mar 13; 290(11):7221-33.

publications Zoi I, Motley MW, Antoniou D, Schramm VL, Schwartz SD. Enzyme Homologues Have Distinct Reaction Paths through Their Transition States. J Phys Chem B. 2015 Mar 5; 119(9):3662-8.

publicationsNicholas MP, Höök P, Brenner S, Wynne CL, Vallee RB, Gennerich A. Control of cytoplasmic dynein force production and processivity by its C-terminal domain. Nat Commun. 2015 Feb 11;6:6206.

publicationsBerko ER, Greally JM. How might epigenetic dysregulation in early embryonic life contribute to autism spectrum disorder? Epigenomics. 2015 Feb; 7(1):1-4.

publications Valenzuela-Iglesias A, Sharma VP, Beaty BT, Ding Z, Gutierrez-Millan LE, Roy P, Condeelis JS, Bravo-Cordero JJ. Profilin1 regulates invadopodium maturation in human breast cancer cells. Eur J Cell Biol. 2015 Feb; 94(2):78-89.

publications  Karp JM, Erylimaz E, Cowburn D. Correlation of chemical shifts predicted by molecular dynamics simulations for partially disordered proteins. J Biomol NMR. 2015 Jan; 61(1):35-45.

publications Rosenblum JM, Wijetunga NA, Fazzari MJ, Krailo M, Barkauskas DA, Gorlick R, Greally JM. Predictive Properties of DNA Methylation Patterns in Primary Tumor Samples for Osteosarcoma Relapse Status. Epigenetics. 2015 Jan 2; 10(1):31-9.

publications Jeon H, Vigdorovich V, Garrett-Thomson SC, Janakiram M, Ramagopal UA, Abadi YM, Lee JS, Scandiuzzi L, Ohaegbulam KC, Chinai JM, Zhao R, Yao Y, Mao Y, Sparano JA, Almo SC, Zang X. Structure and cancer immunotherapy of the b7 family member b7x. Cell Rep.2014 Nov 6; 9(3):1089-98.

publications  Shemesh A, Wang Y, Yang Y, Yang GS, Johnson DE, Backer JM, Pessin JE, Zong H. Suppression of mTOR1 activation in acid- α -glucosidase deficient cells and mice is ameliorated by leucine supplementation. Am J Physiol Regul Integr Comp Physiol. 2014 Nov 15; 307(10):R1251-9.

publications  Campbell PD, Shen K, Sapio MR, Glenn TD, Talbot WS, Marlow FL. Unique Function of Kinesin Kif5A in Localization of Mitochondria in Axons. J Neurosci. 2014 Oct 29; 34(44):14717-32.

publications  Wijetunga NA, Delahaye F, Zhao YM, Golden A, Mar JC, Einstein FH, Greally JM. The meta-epigenomic structure of purified human stem cell populations is defined at cis-regulatory sequences. Nat Comm. 2014 Oct 20; 5:5195.

publications Delahaye F, Wijetunga NA, Heo HJ, Tozour JN, Zhao YM, Greally JM, Einstein FH. Sexual dimorphism in epigenomic responses of stem cells to extreme fetal growth. Nat Commun. 2014 Oct 10; 5:5187.

publications  Hartung O, Forbes MM, Marlow FL. Zebrafish vasa is required for germ-cell differentiation and maintenance. Mol Reprod Dev. 2014 Oct; 81(10):946-61.

publications  Keller CJ, Honey CJ, Mégevand P, Entz L, Ulbert I, Mehta AD. Mapping human brain networks with cortico-cortical evoked potentials. Philos Trans R Soc Lond B Biol Sci. 2014 Oct 5; 369(1653) pii: 20130528.

publications  Beaty BT, Condeelis J. Digging a little deeper: The stages of invadopodium formation and maturation. Eur J Cell Biol. 2014 Oct; 93(10-12):438-44.

publications  Schneider JL, Suh Y, Cuervo AM. Deficient Chaperone-Mediated Autophagy in Liver Leads to Metabolic Dysregulation. Cell Metab. 2014 Sep 2; 20(3):417-32.

publications  Shin DS, Jordan A, Basu S, Thomas RM, Bandyopadhyay S, de Zoeten EF, Wells AD, Macian F. Regulatory T cells suppress CD4+ T cells through NFAT-dependent transcriptional mechanisms. EMBO Rep. 2014 Sep;1 5(9):991-9.

publications  Manning EP, Laskowski LK, Nelson LS, Touger M. Young woman with epigastric pain and vomiting. Ann Emerg Med. 2014 Sep; 64(3):330-3.

publications Charles SH, Tow AC, Verghese J. Objective cardiac markers and cerebrovascular lesions in Indian seniors. J Epidemiol Glob Health. 2014 Sep; 4(3):245-7.

publications  Fremont R, Calderon DP, Maleki S, Khodakhah K. Abnormal high-frequency burst firing of cerebellar neurons in rapid-onset dystonia-parkinsonism. J Neurosci. 2014 Aug 27; 34(35):11723-32.

publications Díaz-Balzac CA, Lázaro-Peñao MI, Tecle E, Gomez N, Bülow HE. Complex Cooperative Functions of Heparan Sulfate Proteoglycans Shape Nervous System Development in Caenorhabditis elegans. G3 (Bethesda). 2014 Aug 5; 4(10):1859-70. 

publications van Oers JM, Edwards Y, Chahwan R, Zhang W, Smith C, Pechuan X, Schaetzlein S, Jin B, Wang Y, Bergman A, Scharff MD, Edelmann W. The MutSβ complex is a modulator of p53-driven tumorigenesis through its functions in both DNA double-strand break repair and mismatch repair. Oncogene. 2014 Jul 24; 33(30):3939-46.

publications Zhou ZN, Sharma VP, Beaty BT, Roh-Johnson M, Peterson EA, Van Rooijen N, Kenny PA, Wiley HS, Condeelis JS, Segall JE. Autocrine HBEGF expression promotes breast cancer intravasation, metastasis and macrophage-independent invasion in vivo. Oncogene. 2014 Jul 17; 33(29):3784-93.

publications Hazan RB, Kim S, Yao J, Suyama K, Qian X, Qian BZ, Bandyopadhyay S, Loudig OD, De Leon-Rodriguez C, Zhou ZN, Segall JE, Macian F, Norton L. Slug Promotes Survival during Metastasis through Suppression of Puma-mediated Apoptosis. Cancer Res. 2014 Jul 15; 74(14):3695-706.

publications Kwon M, Lee SJ, Wang Y, Rybak Y, Luna A, Reddy S, Adem A, Beaty BT, Condeelis JS, Libutti SK. Filamin A interacting protein 1-like inhibits WNT signaling and MMP expression to suppress cancer cell invasion and metastasis. Int J Cancer. 2014 Jul 1; 135(1):48-60.

publications  Wengerter BC, Katakowski JA, Rosenberg J, Park CG, Almo SC, Palliser D, Levy M. Aptamer-Targeted Antigen Delivery. Mol Ther. 2014 Jul; 22(7):1375-87.

publications Sussman ES, Chen S, Sussman-Fort J, Dinces E. The Five Myths of MMN: Redefining How to Use MMN in Basic and Clinical Research. Brain Topogr. 2014 Jul; 27(4):553-64.

publications  Keller CJ, Honey CJ, Entz L, Bickel S, Groppe DM, Toth E, Ulbert I, Lado FA, Mehta AD. Corticocortical evoked potentials reveal projectors and integrators in human brain networks. J Neurosci. 2014 Jul 2; 34(27):9152-63.

publications  Nakahara F, Weiss CN, Ito K. The role of PML in hematopoietic and leukemic stem cell maintenance.Int J Hematol. 2014 Jul; 100(1):18-26.  

publications O'Rourke BP, Gomez-Ferreria MA, Berk RH, Hackl AM, Nicholas MP, O'Rourke SC, Pelletier L, Sharp DJ. Cep192 Controls the Balance of Centrosome and Non-Centrosomal Microtubules during Interphase. PLoS One. 2014 Jun 27; 9(6):e101001.

publications Soudja SM, Chandrabos C, Yakob E, Veenstra M, Palliser D, Lauvau G. Memory-T-Cell-Derived Interferon-γ Instructs Potent Innate Cell Activation for Protective Immunity. Immunity. 2014 Jun 19; 40(6):974-988.

publications Moore RK, Abdullah S, Tardiff JC. Allosteric effects of cardiac troponin TNT1 mutations on actomyosin binding: A novel pathogenic mechanism for hypertrophic cardiomyopathy. Arch Biochem Biophys. 2014 Jun 15; 552-553:21-8.

publications Varshney AK, Wang X, Aguilar JL, Scharff MD, Fries BC. Isotype Switching Increases Efficacy of Antibody Protection against Staphylococcal Enterotoxin B-Induced Lethal Shock and Staphylococcus aureus Sepsis in Mice. MBio. 2014 Jun 10; 5(3). pii: e01007-14.

publications Beaty BT, Wang Y, Bravo-Cordero JJ, Sharma VP, Miskolci V, Hodgson L, Condeelis J. Talin regulates moesin-NHE-1 recruitment to invadopodia and promotes mammary tumor metastasis. J Cell Biol. 2014 Jun 9; 205(5):737-51.

publications Brojatsch J, Lima H, Kar AK, Jacobson LS, Muehlbauer SM, Chandran K, Diaz-Griffero F. A proteolytic cascade controls lysosome rupture and necrotic cell death mediated by lysosome-destabilizing adjuvants. PLoS One. 2014 Jun 3;9(6):e95032.

publications Ezzati A, Jiang J, Katz MJ, Sliwinski MJ, Zimmerman ME, Lipton RB. Validation of the Perceived Stress Scale in a community sample of older adults. Int J Geriatr Psychiatry. 2014 Jun; 29(6):645-52.

publications  Berko ER, Suzuki M, Beren F, Lemetre C, Alaimo CM, Calder RB, Ballaban-Gil K, Gounder B, Kampf K, Kirschen J, Maqbool SB, Momin Z, Reynolds DM, Russo N, Shulman L, Stasiek E, Tozour J, Valicenti-McDermott M, Wang S, Abrahams BS, Hargitai J, Inbar D, Zhang Z, Buxbaum JD, Molholm S, Foxe JJ, Marion RW, Auton A, Greally JM. Mosaic epigenetic dysregulation of ectodermal cells in autism spectrum disorder. PLoS Genet. 2014 May 29; 10(5):e1004402.

publications  Sussman-Fort J, Sussman E. The effect of stimulus context on the buildup to stream segregation. Front Neurosci. 2014 Apr 29; 8:93. doi: 10.3389/fnins.2014.00093

publications Díaz-Balzac CA, Vázquez-Figueroa LD, García-Arrarás JE. Novel markers identify nervous system components of the holothurian nervous system. Invert Neurosci. 22014 Sep; 14(2):113-25.

publications Koellhoffer JF, Dai Z, Malashkevich VN, Stenglein MD, Liu Y, Toro R, Harrison J, Chandran K, Derisi JL, Almo SC, Lai JR. Structural Characterization of the Glycoprotein GP2 Core Domain from the CAS Virus, a Novel Arenavirus-Like Species. J Mol Biol. 2014 Apr 3; 426(7):1452-68.

publications  Nicholas MP, Rao L, Gennerich A. An improved optical tweezers assay for measuring the force generation of single Kinesin molecules. Methods Mol Biol. 2014; 1136:171-246.

publications  Nicholas MP, Rao L, Gennerich A. Covalent immobilization of microtubules on glass surfaces for molecular motor force measurements and other single-molecule assays. Methods Mol Biol. 2014; 1136:137-69.

publications  Koellhoffer JF, Dai Z, Malashkevich VN, Stenglein MD, Liu Y, Toro R, Harrison J, Chandran K, Derisi JL, Almo SC, Lai JR. Structural Characterization of the Glycoprotein GP2 Core Domain from the CAS Virus, a Novel Arenavirus-Like Species. J Mol Biol. 2014 Apr 3; 426(7):1452-1468.

publications  Gombar S, Maccarthy T, Bergman A. Epigenetics decouples mutational from environmental robustness. Did it also facilitate multicellularity? PLoS Comput Biol. 2014 Mar 6; 10(3):e1003450.

publications Mukhopadhyay A, Quiroz JA, Wolkoff AW. Rab1a Regulates Sorting of Early Endocytic Vesicles. Am J Physiol Gastrointest Liver Physiol. 2014 Mar; 306(5):G412-24.

publicationsSchneider JL, Cuervo AM. Liver autophagy: much more than just taking out the trash. Nat Rev Gastroenterol Hepatol. 2014 Mar; 11(3):187-200.

publications Patterson CA, Duijnhouwer J, Wissig SC, Krekelberg B, Kohn A. Similar adaptation effects in primary visual cortex and area MT of the macaque monkey under matched stimulus conditions. J Neurophysiol. 2014 Mar; 111(6):1203-13.

publications Patterson CAWissig SC, Kohn A. Adaptation disrupts motion integration in the primate dorsal stream. Neuron. 2014 Feb 5; 81(3):674-86.

publications Heim AE, Hartung O, Rothhämel S, Ferreira E, Jenny A, Marlow FL. Oocyte polarity requires a Bucky ball-dependent feedback amplification loop. Development. 2014 Feb; 141(4):842-54.

publications Shemesh A, Abdulla A, Yang F, Chua SC, Pessin JE, Zong H. The antidepressant trans-2-phenylcyclopropylamine protects mice from high-fat-diet-induced obesity. PLoS One. 2014 Feb 21; 9(2):e89199.

publications Portulano C, Paroder-Belenitsky M, Carrasco N. The Na+/I- Symporter (NIS): Mechanism and Medical Impact. Endocr Rev. 2014 Feb; 35(1):106-49.

publications Arora P, Baena A, Yu KO, Saini NK, Kharkwal SS, Goldberg MF, Kunnath-Velayudhan S, Carreño LJ, Venkataswamy MM, Kim J, Lazar-Molnar E, Lauvau G, Chang YT, Liu Z, Bittman R, Al-Shamkhani A, Cox LR, Jervis PJ, Veerapen N, Besra GS, Porcelli SA. A Single Subset of Dendritic Cells Controls the Cytokine Bias of Natural Killer T Cell Responses to Diverse Glycolipid Antigens. Immunity. 2014 Jan 16; 40(1):105-16.

publications Weiss CN, Ito K. DNA damage response, redox status and hematopoiesis. Blood Cells Mol Dis. 2014 Jan; 52(1):12-8.

publications Briggs SW, Mowrey W, Hall CB, Galanopoulou AS. CPP-115, a vigabatrin analogue, decreases spasms in the multiple-hit rat model of infantile spasms. Epilepsia. 2014 Jan; 55(1):94-102.

publications Koellhoffer JF, Higgins CD, Lai JR. Protein engineering strategies for the development of viral vaccines and immunotherapeutics. FEBS Lett. 2014 Jan 21; 588(2):298-307.

publications Ayers EI, Tow AC, Holtzer R, Verghese J. Walking while Talking and Falls in Aging. Gerontology.2014; 60(2):108-13.

publications Stock AD, Wen J, Putterman C. Neuropsychiatric Lupus, the Blood Brain Barrier, and the TWEAK/Fn14 Pathway. Front Immunol. 2013 Dec 25; 4:484.

publications Ooi YS, Stiles KM, Liu CY, Taylor GM, Kielian M. Genome-Wide RNAi Screen Identifies Novel Host Proteins Required for Alphavirus Entry. PLoS Pathog. 2013 Dec; 9(12):e1003835.

publications Megra B, Eugenin E, Roberts T, Morgello S, Berman JW. Protease Resistant Protein Cellular Isoform (PrP(c)) as a Biomarker: Clues into the Pathogenesis of HAND. J Neuroimmune Pharmacol. 2013 Dec; 8(5):1159-66.

publications Schneider JL, Cuervo AM. Chaperone-mediated autophagy: dedicated saviour and unfortunate victim in the neurodegeneration arena. Biochem Soc Trans. 2013 Dec 1; 41(6):1483-8.

publications Martinez-Lopez N, Athonvarangkul D, Mishall P, Sahu S, Singh R. Autophagy proteins regulate ERK phosphorylation. Nat Commun. 2013 Nov 18; 4:2799.

publications Zhang Y, Evans GB, Clinch K, Crump DR, Harris LD, Fröhlich R, Tyler PC, Hazleton KZ, Cassera MB, Schramm VL. Transition State Analogues of Plasmodium falciparum and Human Orotate Phosphoribosyltransferases. J Biol Chem. 2013 Nov 29; 288(48):34746-54.

publications Salzberg Y, Díaz-Balzac CA, Ramirez-Suarez NJ, Attreed M, Tecle E, Desbois M, Kaprielian Z, Bülow HE. Skin-Derived Cues Control Arborization of Sensory Dendrites in Caenorhabditis elegansCell. 2013 Oct 10; 155(2):308-320.

publications Gross DA, Silver DL. Purification of Integral Membrane Proteins and Lipid-Binding Assays. Methods Cell Biol. 2013; 116C:191-211.

publications Campbell PD, Marlow FL. Temporal and tissue specific gene expression patterns of the zebrafish kinesin-1 heavy chain family, kif5s, during development. Gene Expr Patterns. 2013 Oct; 13(7):271-9.

publications Higgins CD, Koellhoffer JF, Chandran K, Lai JR. C-peptide inhibitors of Ebola virus glycoprotein-mediated cell entry: Effects of conjugation to cholesterol and side chain-side chain crosslinking. Bioorg Med Chem Lett. 2013 Oct 1; 23(19):5356-60.

publications Uchime O, Fields W, Kielian M. The Role of E3 in pH Protection during Alphavirus Assembly and Exit.J Virol. 2013 Sep; 87(18):10255-62.

publications Clinch K, Crump DR, Evans GB, Hazleton KZ, Mason JM, Schramm VL, Tyler PC. Acyclic phosph(on)ate inhibitors of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase. Bioorg Med Chem. 2013 Sep 1; 21(17):5629-46.

publications Park C, Cuervo AM. Selective Autophagy: Talking with the UPS. Cell Biochem Biophys. 2013 Sep; 67(1):3-13.

publications Roche CJ, Dantsker D, Heller ER, Sabat JE, Friedman JM. Reverse micelles as a tool for probing solvent modulation of protein dynamics: Reverse micelle encapsulated hemoglobin. Chem Phys. 2013 Aug 30; 430:88-97.

publications Ishihara D, Dovas A, Hernandez L, Pozzuto M, Wyckoff J, Segall JE, Condeelis JS, Bresnick AR, Cox D. Wiskott-Aldrich Syndrome Protein Regulates Leukocyte-Dependent Breast Cancer Metastasis. Cell Rep.2013 Aug 15; 4(3):429-36.

publications Martinez-Lopez N, Athonvarangkul D, Sahu S, Coletto L, Zong H, Bastie CC, Pessin JE, Schwartz GJ, Singh R. Autophagy in Myf5+ progenitors regulates energy and glucose homeostasis through control of brown fat and skeletal muscle development. EMBO Rep. 2013 Aug 30; 14(9):795-803.

publications Brunner R, Ng CL, Aissaoui H, Akabas MH, Boss C, Brun R, Callaghan PS, Corminboef O, Fidock DA,Frame IJ, Heidmann B, Le Bihan A, Jenö P, Mattheis C, Moes S, Müller IB, Paguio M, Roepe PD, Siegrist R, Voss T, Welford RW, Wittlin S, Binkert C. UV-triggered Affinity-Capture Identifies Interactions Between the Plasmodium falciparum Multidrug Resistance Protein 1 (PfMDR1) and Antimalarial Agents in Live Parasitized Cells. J Biol Chem. 2013 Aug 2; 288(31):22576-83.

publications McMillan PJ, Millet C, Batinovic S, Maiorca M, Hanssen E, Kenny S, Muhle RA, Melcher M, Fidock DA, Smith JD, Dixon MW, Tilley L. Spatial and temporal mapping of the PfEMP1 export pathway in Plasmodium falciparum. Cell Microbiol. 2013 Aug; 15(8):1401-1418.

publications Rao L, Romes EM, Nicholas MP, Brenner S, Tripathy A, Gennerich A, Slep KC. The Yeast Dynein Dyn2-Pac11 Complex is a Dynein Dimerization/Processivity Factor: Structural and Single Molecule Characterization. Mol Biol Cell. 2013 Aug; 24(15):2362-2377.

publications Sroubek JKrishnan Y, McDonald TV. Sequence and structure-specific elements of HERG mRNA determine channel synthesis and trafficking efficiency. FASEB J. 2013 Aug; 27(8):3039-53.

publications Eryilmaz E, Janda A, Kim J, Cordero RJ, Cowburn D, Casadevall A. Global structures of IgG isotypes expressing identical variable regions. Mol Immunol. 2013 Jul 31; 56(4):588-598.

publications Steinberg LJ, Fischer BJ, Peña JL. Binaural gain modulation of spectrotemporal tuning in the interaural level difference-coding pathway. J Neurosci. 2013 Jul 3; 33(27):11089-99.

publications Zhao R, Chinai JM, Buhl S, Scandiuzzi L, Ray A, Jeon H, Ohaegbulam KC, Ghosh K, Zhao A, Scharff MD, Zang X. HHLA2 is a member of the B7 family and inhibits human CD4 and CD8 T-cell function. Proc Natl Acad Sci U S A. 2013 Jun 11; 110(24):9879-84.

publications Beaty BT, Sharma VP, Bravo-Cordero JJ, Simpson MA, Eddy RJ, Koleske AJ, Condeelis J. β1 integrin regulates Arg to promote invadopodial maturation and matrix degradation. Mol Biol Cell. 2013 Jun; 24(11):1661-75.

publications Wen J, Xia Y, Stock A, Michaelson JS, Burkly LC, Gulinello M, Putterman C. Neuropsychiatric disease in murine lupus is dependent on the TWEAK/Fn14 pathway. J Autoimmun. 2013 Jun; 43:44-54.

publications Lima H Jr*, Jacobson LS*, Goldberg MF, Chandran K, Diaz-Griffero F, Lisanti MP, Brojatsch J. Role of lysosome rupture in controlling Nlrp3 signaling and necrotic cell death. Cell Cycle. 2013 Jun 15; 12(12):1868-78. (*contributed equally)

publications Will B, Vogler TO, Bartholdy B, Garrett-Bakelman F, Mayer J, Barreyro L, Pandolfi A, Todorova TI,Okoye-Okafor UCStanley RF, Bhagat TD, Verma A, Figueroa ME, Melnick A, Roth M, Steidl U. Satb1 regulates the self-renewal of hematopoietic stem cells by promoting quiescence and repressing differentiation commitment. Nat Immunol. 2013 May; 14(5):437-45.

publications Qian X, Hulit J, Suyama K, Eugenin EA, Belbin TJ, Loudig O, Smirnova T, Zhou ZN, Segall J, Locker J, Phillips GR, Norton L, Hazan RB. p21CIP1 mediates reciprocal switching between proliferation and invasion during metastasis. Oncogene. 2013 May 2; 32(18):2292-303, 2303.e1-7.

publications Schoenfeld BP, Choi RJ, Choi CH, Terlizzi AM, Hinchey P, Kollaros M, Ferrick NJ, Koenigsberg E, Ferreiro D, Leibelt DA, Siegel SJ, Bell AJ, McDonald TV, Jongens TA, McBride SM. The Drosophila DmGluRA is required for social interaction and memory. Front Pharmacol. 2013 May 23; 4:64. doi: 10.3389/fphar.2013.00064.

publications Moore RKGrinspan LTJimenez J, Guinto PJ, Ertz-Berger B, Tardiff JC. HCM-Linked Δ160E Cardiac Troponin T Mutation Causes Unique Progressive Structural and Molecular Ventricular Remodeling in Transgenic Mice. J Mol Cell Cardiol. 2013 May; 58:188-98.

publications Xia Y, Janda A, Eryilmaz E, Casadevall A, Putterman C. The constant region affects antigen binding of antibodies to DNA by altering secondary structure. Mol Immunol. 2013 May 8; 56(1-2):28-37.

publications Regula LK, Harris R, Wang F, Higgins CD, Koellhoffer JF, Zhao Y, Chandran K, Gao J, Girvin ME, Lai JR. Conformational Properties of Peptides Corresponding to the Ebolavirus GP2 Membrane-Proximal External Region in the Presence of Micelle-Forming Surfactants and Lipids. Biochemistry. 2013 May 21; 52(20):3393-404.

publications Garcia-Solache MA, Izquierdo-Garcia D, Smith C, Bergman A, Casadevall A. Fungal virulence in a lepidopteran model is an emergent property with deterministic features. MBio. 2013 Apr 30; 4(3). doi:pii: e00100-13. 10.1128/mBio.00100-13.

publications Chow SK, Smith C, Maccarthy T, Pohl MA, Bergman A, Casadevall A. Disease-enhancing antibodies improve the efficacy of bacterial toxin-neutralizing antibodies. Cell Host Microbe. 2013 Apr 17; 13(4):417-28.

publications Keller CJ, Bickel S, Honey CJ, Groppe DM, Entz L, Craddock RC, Lado FA, Kelly C, Milham M, Mehta AD. Neurophysiological Investigation of Spontaneous Correlated and Anticorrelated Fluctuations of the BOLD Signal. J Neurosci. 2013 Apr 10; 33(15):6333-6342.

publications Diaz F, McKeehan N, Kang W, Hébert JM. Apoptosis of glutamatergic neurons fails to trigger a neurogenic response in the adult neocortex. J Neurosci. 2013 Apr 10; 33(15):6278-84.

publications Lu X, Wontakal SN, Kavi H, Kim BJ, Guzzardo PM, Emelyanov AV, Xu N, Hannon GJ, Zavadil J, Fyodorov DV, Skoultchi AI. Drosophila H1 regulates the genetic activity of heterochromatin by recruitment of Su(var)3-9. Science. 2013 Apr 5; 340(6128):78-81.

publications Abadi YM, Jeon H, Ohaegbulam KC, Scandiuzzi L, Ghosh K, Hofmeyer KA, Lee JS, Ray A, Gravekamp C, Zang X. Host B7x Promotes Pulmonary Metastasis of Breast Cancer. J Immunol. 2013 Apr 1; 190(7):3806-14.

publications Wang Y, Wu B, Chamberlain AA, Lui W, Koirala P, Susztak K, Klein D, Taylor V, Zhou B. Endocardial to myocardial notch-wnt-bmp axis regulates early heart valve development. PLoS One. 2013; 8(4):e60244.

publications Palacios-Prado N, Hoge G, Marandykina A, Rimkute L, Chapuis S, Paulauskas N, Skeberdis VA, O'Brien J, Pereda AE, Bennett MV, Bukauskas FF. Intracellular magnesium-dependent modulation of gap junction channels formed by neuronal connexin36. J Neurosci. 2013 Mar 13; 33(11):4741-53.

publications Yu Y, Mo Y, Ebenezer D, Bhattacharyya S, Liu H, Sundaravel S, Wonkatal S, Cartier J, Caces B, Artz A, Nischal S, Bhagat T, Bathon K, Maqbool S, Gligich O, Suzuki M, Steidl U, Godley L, Skoultchi A, Greally J, Wickrema A, Verma A. High resolution methylome analysis reveals widespread functional hypomethylation during adult human erythropoiesis. J Biol Chem. 2013 Mar 29; 288(13):8805-14.

publications Jacobson LS, Lima H, Goldberg MF, Gocheva V, Tsiperson V, Sutterwala FS, Joyce JA, Gapp BV, Blomen VA, Chandran K, Brummelkamp TR, Diaz-Griffero F, Brojatsch J. Cathepsin-mediated necrosis controls the adaptive immune response by Th2-associated adjuvants. J Biol Chem. 2013 Mar 15; 288(11):7481-91.

publications Sabat J, Egawa T, Lu C, Stuehr DJ, Gerfen GJ, Rousseau DL, Yeh SR. Catalytic intermediates of inducible nitric oxide synthase stabilized by the W188H mutation. J Biol Chem. 2013 Mar 1; 288(9):6095-106.

publications Entenberg D, Kedrin D, Wyckoff J, Sahai E, Condeelis J, Segall JE. Imaging tumor cell movement in vivo. Curr Protoc Cell Biol. 2013 Mar; Chapter 19:Unit19.7.

publications Tecle E, Diaz-Balzac CA, Bülow HE. Distinct 3-O-Sulfated Heparan Sulfate Modification Patterns Are Required for kal-1-Dependent Neurite Branching in a Context-Dependent Manner in Caenorhabditis elegans. G3 (Bethesda). 2013 Mar; 3(3):541-52.

publications Abe BT, Macian F. Uncovering the mechanisms that regulate tumor-induced T-cell anergy.Oncoimmunology. 2013 Feb 1; 2(2):e22679.

publications Lombino F, Biundo F, Tamayev R, Arancio O, D'Adamio L. An Intracellular Threonine of Amyloid-β Precursor Protein Mediates Synaptic Plasticity Deficit and Memory Loss. PLoS One. 2013; 8(2):e57120.

publications Klein ME, Younts TJ, Castillo PE, Jordan BA. RNA-binding protein Sam68 controls synapse number and local β-actin mRNA metabolism in dendrites. Proc Natl Acad Sci U S A. 2013 Feb 19; 110(8):3125-30.

publications Pandolfi A, Barreyro L, Steidl U. Concise review: preleukemic stem cells: molecular biology and clinical implications of the precursors to leukemia stem cells. Stem Cells Transl Med. 2013 Feb; 2(2):143-50.

publications Wissig SCPatterson CA, Kohn A. Adaptation improves performance on a visual search task. J Vis.2013 Feb 6; 13(2). doi:pii: 6. 10.1167/13.2.6.

publications Baine I, Basu S, Ames R, Sellers RS, Macian F. Helios Induces Epigenetic Silencing of Il2 Gene Expression in Regulatory T Cells. J Immunol. 2013 Feb 1; 190(3):1008-16.

publications Suk HY, Zhou C, Yang TT, Zhu H, Yu RY, Olabisi O, Yang X, Brancho D, Kim JY, Scherer PE, Frank PG, Lisanti MP, Calvert JW, Lefer DJ, Molkentin JD, Ghigo A, Hirsch E, Jin J, Chow CW. Ablation of Calcineurin Aβ Reveals Hyperlipidemia and Signaling Crosstalks with Phosphodiesterases. J Biol Chem.2013 Feb 1; 288(5):3477-88.

publications Tsiperson V, Gruber RC, Goldberg MF, Jordan A, Weinger JG, Macian F, Shafit-Zagardo B. Suppression of Inflammatory Responses during Myelin Oligodendrocyte Glycoprotein-Induced Experimental Autoimmune Encephalomyelitis Is Regulated by AKT3 Signaling. J Immunol. 2013 Feb 15; 190(4):1528-39.

publications Patterson CAWissig SC, Kohn A. Distinct effects of brief and prolonged adaptation on orientation tuning in primary visual cortex. J Neurosci. 2013 Jan 9; 33(2):532-43.

publications Forest SK, Acker CM, d'Abramo C, Davies P. Methods for Measuring Tau Pathology in Transgenic Mouse Models. J Alzheimers Dis. 2013 Jan 1; 33(2):463-71.

publications Pereda AE, Curti S, Hoge G, Cachope R, Flores CE, Rash JE. Gap junction-mediated electrical transmission: Regulatory mechanisms and plasticity. Biochim Biophys Acta. 2013 Jan; 1828(1):134-46.

publications Tamayev R, Akpan N, Arancio O, Troy CM, D'Adamio L. Caspase-9 mediates synaptic plasticity and memory deficits of Danish dementia knock-in mice: caspase-9 inhibition provides therapeutic protection.Mol Neurodegener. 2012 Dec 10; 7:60.

publications Koellhoffer JF, Chen G, Sandesara RG, Bale S, Ollmann Saphire E, Chandran K, Sidhu SS, Lai JR. Two Synthetic Antibodies that Recognize and Neutralize Distinct Proteolytic Forms of the Ebola Virus Envelope Glycoprotein. Chembiochem. 2012 Nov 26; 13(17):2549-57.

publications Krishnan A, Miller EH, Herbert AS, Ng M, Ndungo E, Whelan SP, Dye JM, Chandran K. Niemann-Pick C1 (NPC1)/NPC1-like1 chimeras define sequences critical for NPC1's function as a flovirus entry receptor.Viruses. 2012 Oct 25;4(11):2471-84.

publications Berger JH, Charron MJ, Silver DL. Major Facilitator Superfamily Domain-Containing Protein 2a (MFSD2A) Has Roles in Body Growth, Motor Function, and Lipid Metabolism. PLoS One. 2012; 7(11):e50629.

publications Koellhoffer JF, Malashkevich VN, Harrison JS, Toro R, Bhosle RC, Chandran K, Almo SC, Lai JR. Crystal Structure of the Marburg Virus GP2 Core Domain in Its Postfusion Conformation. Biochemistry.2012 Oct 2;51(39):7665-75.

publications Janda A, Eryilmaz E, Nakouzi A, Cowburn D, Casadevall A. Variable region identical immunoglobulins differing in isotype express different paratopes. J Biol Chem. 2012 Oct 12;287(42):35409-17.

publications Frame IJ, Merino EF, Schramm VL, Cassera MB, Akabas MH. Malaria Parasite Type 4 Equilibrative Nucleoside Transporters (ENT4) are Purine Transporters with Distinct Substrate Specificity. Biochem J.2012 Sep 1; 446(2):179-90.

publications Nicola AM, Albuquerque P, Martinez LR, Dal-Rosso RA, Saylor C, De Jesus M, Nosanchuk JD, Casadevall A. Macrophage Autophagy in Immunity to Cryptococcus neoformans and Candida albicans.Infect Immun. 2012 Sep; 80(9):3065-76.

publications Abe BTShin DS, Mocholi E, Macian F. NFAT1 supports tumor-induced anergy of CD4+ T cells. Cancer Res. 2012 Sep 15;72(18):4642-51.

publications Kawahara M*, Pandolfi A*, Bartholdy B, Barreyro L, Will B, Roth M, Okoye-Okafor UC, Todorova TI, Figueroa ME, Melnick A, Mitsiades CS, Steidl U. H2.0-like Homeobox Regulates Early Hematopoiesis and Promotes Acute Myeloid Leukemia. Cancer Cell. 2012 Aug 14; 22(2):194-208. (*Contributed equally)

publications Moir RD, Gross DA, Silver DL, Willis IM. SCS3 and YFT2 Link Transcription of Phospholipid Biosynthetic Genes to ER Stress and the UPR. PLoS Genet. 2012 Aug; 8(8):e1002890.

publications Xia Y, Campbell SR, Broder A, Herlitz L, Abadi M, Wu P, Michaelson JS, Burkly LC, Putterman C. Inhibition of the TWEAK/Fn14 pathway attenuates renal disease in nephrotoxic serum nephritis. Clin Immunol. 2012 Aug 20; 145(2):108-121.

publications Barreyro L, Will B, Bartholdy B, Zhou L, Todorova TI, Stanley RF, Ben-Neriah S, Montagna C, Parekh S, Pellagatti A, Boultwood J, Paietta E, Ketterling RP, Cripe L, Fernandez HF, Greenberg PL, Tallman MS, Steidl C, Mitsiades CS, Verma A, Steidl U. Overexpression of interleukin 1 receptor accessory protein in stem and progenitor cells and outcome correlation in AML and MDS. Blood. 2012 Aug 9; 120(6):1290-8.

publications Roberts TK, Eugenin EA, Lopez L, Romero IA, Weksler BB, Couraud PO, Berman JW. CCL2 disrupts the adherens junction: implications for neuroinflammation. Lab Invest. 2012 Aug; 92(8):1213-33.

publications Manning EP, Tardiff JC, Schwartz SD. Molecular Effects of Familial Hypertrophic Cardiomyopathy-Related Mutations in the TNT1 Domain of cTnT. J Mol Biol. 2012 Aug 3; 421(1):54-66.

publications Krishnan Y, Li Y, Zheng R, Kanda V, McDonald TV. Mechanisms underlying the protein-kinase mediated regulation of the HERG potassium channel synthesis. Biochim Biophys Acta. 2012 Aug; 1823(8):1273-84.

publications Casadevall A, Janda A. Immunoglobulin isotype influences affinity and specificity. Proc Natl Acad Sci U S A. 2012 Jul 31; 109(31):12272-3.

publications Hazleton KZ, Ho MC, Cassera MB, Clinch K, Crump DR, Rosario I Jr, Merino EF, Almo SC, Tyler PC, Schramm VL. Acyclic Immucillin Phosphonates: Second-Generation Inhibitors of Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase. Chem Biol. 2012 Jun 22; 19(6):721-30.

publications Hulit J, Kedrin D, Gligorijevic B, Entenberg D, Wyckoff J, Condeelis J, Segall JE. The use of fluorescent proteins for intravital imaging of cancer cell invasion. Methods Mol Biol. 2012; 872:15-30.

publications Kim M, Kim C, Choi YS, Kim M, Park C, Suh Y. Age-related alterations in mesenchymal stem cells related to shift in differentiation from osteogenic to adipogenic potential: Implication to age-associated bone diseases and defects. Mech Ageing Dev. 2012 May; 133(5):215-225.

publications McKinnon NK, Bali M, Akabas MH. Length and Amino Acid Sequence of Peptides Substituted for the 5-HT3A Receptor M3M4 Loop May Affect Channel Expression and Desensitization. PLoS One. 2012; 7(4):e35563.

publications Chen J, Angeletti R, McDonald TV, Xiao H. Binding interface of cardiac potassium channel proteins identified by hydrogen deuterium exchange of synthetic peptides. Anal Bioanal Chem. 2012 May; 403(5):1303-9.

publications Wilner SE, Wengerter B, Maier K, de Lourdes Borba Magalhães M, Del Amo DS, Pai S, Opazo F, Rizzoli SO, Yan A, Levy M. An RNA alternative to human transferrin: a new tool for targeting human cells. Mol Ther Nucleic Acids. 2012 May 15; 1:e21.

publications Pawar RD, Pitashny M, Gindea S, Tan Tieng A, Levine B, Goilav B, Campbell SR, Xia Y, Qing X, Thomas D, Herlitz L, Berger T, Mak TM, Putterman C. Neutrophil gelatinase associated lipocalin is instrumental in the pathogenesis of antibody-mediated nephritis. Arthritis Rheum. 2012 May; 64(5):1620-31.

publications Tamayev R, D'Adamio L. Memory deficits of british dementia knock-in mice are prevented by aβ-precursor protein haploinsufficiency. J Neurosci. 2012 Apr 18; 32(16):5481-5.

publications Bravo-Ambrosio A, Mastick G, Kaprielian Z. Motor axon exit from the mammalian spinal cord is controlled by the homeodomain protein Nkx2.9 via Robo-Slit signaling. Development. 2012 Apr; 139(8):1435-46.

publications Liu CY, Kielian M. Identification of a Specific Region in the E1 Fusion Protein Involved in Zinc Inhibition of Semliki Forest Virus Fusion. J Virol. 2012 Apr; 86(7):3588-94.

publications Fremont R, Khodakhah K. Alternative Approaches to Modeling Hereditary Dystonias.Neurotherapeutics. 2012 Apr; 9(2):315-22.

publications Han G, Nguyen LN, Macherla C, Friedman JM, Nosanchuk JD, Martinez LR. Nitric Oxide-Releasing Nanoparticles Accelerate Wound Healing by Promoting Fibroblast Migration and Collagen Deposition. Am J Pathol. 2012 Apr; 180(4):1465-73.

publications Xiao H, Wang H, Zhang X, Tu Z, Bulinski C, Khrapunovich-Baine M, Hogue Angeletti R, Horwitz SB. Structural Evidence for Cooperative Microtubule Stabilization by Taxol and the Endogenous Dynamics Regulator MAP4. ACS Chem Biol. 2012 Apr 20; 7(4):744-52.

publications Manning EP, Guinto PJ, Tardiff JC. Correlation of molecular and functional effects of mutations in cardiac troponin T linked to familial hypertrophic cardiomyopathy: An integrative in silico - in vitro approach. J Biol Chem. 2012 Apr 27; 287(18):14515-23.

publications Miller EH, Chandran K. Filovirus entry into cells - new insights. Curr Opin Virol. 2012 Apr; 2(2):206-14.

publications Hazleton JE, Berman JW, Eugenin EA. Purinergic Receptors Are Required for HIV-1 Infection of Primary Human Macrophages. J Immunol. 2012 Mar 26; 188(9):4488-95.

publications Miller EH, Obernosterer G, Raaben M, Herbert AS, Deffieu MS, Krishnan A, Ndungo E, Sandesara RG, Carette JE, Kuehne AI, Ruthel G, Pfeffer SR, Dye JM, Whelan SP, Brummelkamp TR, Chandran K. Ebola virus entry requires the host-programmed recognition of an intracellular receptor. EMBO J. 2012 Mar 6; 31(8):1947-60.

publications Monks DC, Morrow BE. Identification of putative retinoic acid target genes downstream of mesenchymal Tbx1 during inner ear development. Dev Dyn. 2012 Mar; 241(3):563-73.

publications Wontakal SN, Guo X, Smith C, Maccarthy T, Bresnick EH, Bergman A, Snyder MP, Weissman SM, Zheng D, Skoultchi AI. A core erythroid transcriptional network is repressed by a master regulator of myelo-lymphoid differentiation. Proc Natl Acad Sci U S A. 2012 Mar 6; 109(10):3832-7.

publications Kaushik S, Arias E, Kwon H, Lopez NM, Athonvarangkul D, Sahu S, Schwartz GJ, Pessin JE, Singh R. Loss of autophagy in hypothalamic POMC neurons impairs lipolysis. EMBO Rep. 2012 Mar 1; 13(3):258-65.

publications Lai CW, Otero JH, Hendershot LM, Snapp E. ERdj4 is a soluble endoplasmic reticulum DnaJ family protein that interacts with ERAD machinery. J Biol Chem. 2012 Mar 9; 287(11):7969-78.

publications Tamayev R, Matsuda S, Arancio O, D'Adamio L. β- but not γ-secretase proteolysis of APP causes synaptic and memory deficits in a mouse model of dementia. EMBO Mol Med. 2012 Mar; 4(3):171-9.

publications Gligorijevic B, Wyckoff J, Yamaguchi H, Wang Y, Roussos ET, Condeelis J. N-WASP-mediated invadopodium formation is involved in intravasation and lung metastasis of mammary tumors. J Cell Sci.2012 Feb 1; 125(Pt 3):724-34.

publications Tamayev R, Matsuda S, D'Adamio L. β - but not γ-secretase proteolysis of APP causes synaptic and memory deficits in a mouse model of dementia. Mol Neurodegener. 2012 Feb 7; 7 Suppl 1:L9.

publications Paek H, Antoine MW, Diaz F, Hébert JM. Increased β-catenin activity in the anterior neural plate induces ectopic mid-hindbrain characteristics. Dev Dyn. 2012 Feb; 241(2):242-6.

publications Ishihara D, Dovas A, Park H, Isaac BM, Cox D. The chemotactic defect in wiskott-Aldrich syndrome macrophages is due to the reduced persistence of directional protrusions. PLoS One. 2012; 7(1):e30033.

publications Patel VL, Mitra S, Harris R, Buxbaum AR, Lionnet T, Brenowitz M, Girvin M, Levy M, Almo SC, Singer RH, Chao JA. Spatial arrangement of an RNA zipcode identifies mRNAs under post-transcriptional control.Genes Dev. 2012 Jan 1; 26(1):43-53.

publications Sroubek JKrishnan YChinai J, Buhl S, Scharff MD, McDonald TV. The use of Bcl-2 over-expression to stabilize hybridomas specific to the HERG potassium channel. J Immunol Methods. 2012 Jan 31; 375(1-2):215-22.

publications Krishnan Y, Zheng R, Walsh C, Tang Y, McDonald TV. Partially Dominant Mutant Channel Defect Corresponding with Intermediate LQT2 Phenotype. Pacing Clin Electrophysiol. 2012 Jan; 35(1):3-16.

publications Lapidus KA, Nwokafor C, Scott D, Baroni TE, Tenenbaum SA, Hiroi N, Singer RH, Czaplinski K. Transgenic expression of ZBP1 in neurons suppresses cocaine-associated conditioning. Learn Mem. 2012 Jan 12; 19(2):35-42.

publications Bravo-Ambrosio A, Kaprielian Z. Crossing the border: molecular control of motor axon exit. Int J Mol Sci. 2011; 12(12):8539-61.

publications Gross DA, Zhan C, Silver DL. Direct binding of triglyceride to fat storage-inducing transmembrane proteins 1 and 2 is important for lipid droplet formation. Proc Natl Acad Sci U S A. 2011 Dec 6; 108(49):19581-6.

publications Davarifar A, Antoniou D, Schwartz SD. The Promoting Vibration in Human Heart Lactate Dehydrogenase Is a Preferred Vibrational Channel. J Phys Chem B. 2011 Dec 29; 115(51):15439-44.

publications Miranda DA, Koves TR, Gross DA, Chadt A, Al-Hasani H, Cline GW, Schwartz GJ, Muoio DM, Silver DL. Re-patterning of skeletal muscle energy metabolism by Fat storage-Inducing Transmembrane protein 2. J Biol Chem. 2011 Dec 9; 286(49):42188-99.

publications Manzerova J, Krymov V, Gerfen GJ. Investigating the intermediates in the reaction of ribonucleoside triphosphate reductase from Lactobacillus leichmannii: An application of HF EPR-RFQ technology. J Magn Reson. 2011 Dec; 213(1):32-45.

publications Hernandez L, Magalhaes MA, Coniglio SJ, Condeelis JS, Segall JE. Opposing roles of CXCR4 and CXCR7 in breast cancer metastasis. Breast Cancer Res. 2011 Dec 9; 13(6):R128.

publications Chen J, Weber M, Um SY, Walsh CA, Tang Y, McDonald TV. A Dual Mechanism for I(Ks) Current Reduction by the Pathogenic Mutation KCNQ1-S277L. Pacing Clin Electrophysiol. 2011 Dec; 34(12):1652-1664.

publications Paroder-Belenitsky M, Maestas MJ, Dohán O, Nicola JP, Reyna-Neyra A, Follenzi A, Dadachova E, Eskandari S, Amzel LM, Carrasco N. Mechanism of anion selectivity and stoichiometry of the Na+/I- symporter (NIS). Proc Natl Acad Sci U S A. 2011 Nov 1; 108(44):17933-8.

publications Kon M, Kiffin R, Koga H, Chapochnick J, Macian F, Varticovski L, Cuervo AM. Chaperone-mediated autophagy is required for tumor growth. Sci Transl Med. 2011 Nov 16; 3(109):109ra117.

publications Schlatterer SD, Acker CM, Davies P. c-Abl in Neurodegenerative Disease. J Mol Neurosci. 2011 Nov; 45(3):445-52.

publications Magalhaes MA, Larson DR, Mader CC, Bravo-Cordero JJ, Gil-Henn H, Oser M, Chen X, Koleske AJ, Condeelis J. Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway. J Cell Biol. 2011 Nov 28; 195(5):903-20.

publications Suzuki M, Oda M, Ramos MP, Pascual M, Lau K, Stasiek E, Agyiri F, Thompson RFGlass JL, Jing Q, Sandstrom R, Fazzari MJ, Hansen RS, Stamatoyannopoulos JA, McLellan AS, Greally JM. Late-replicating heterochromatin is characterized by decreased cytosine methylation in the human genome. Genome Res.2011 Nov; 21(11):1833-40.

publications Cassera MB, Hazleton KZ, Merino EF, Obaldia N 3rd, Ho MC, Murkin AS, Depinto R, Gutierrez JA, Almo SC, Evans GB, Babu YS, Schramm VL. Plasmodium falciparum Parasites Are Killed by a Transition State Analogue of Purine Nucleoside Phosphorylase in a Primate Animal Model. PLoS One. 2011; 6(11):e26916.

publications Casimiro TM, Sossa KG, Uzunova G, Beattie JB, Marsden KC, Carroll RC. mGluR and NMDAR activation internalize distinct populations of AMPARs. Mol Cell Neurosci. 2011 Oct; 48(2):161-70.

publications McKinnon NK*, Reeves DC*, Akabas MH. 5-HT3 receptor ion size selectivity is a property of the transmembrane channel, not the cytoplasmic vestibule portals. J Gen Physiol. 2011 Oct; 138(4):453-66. *Contributed equally.

publications Yu MA, Egawa T, Shinzawa-Itoh K, Yoshikawa S, Yeh SR, Rousseau DL, Gerfen GJ. Radical formation in cytochrome c oxidase. Biochim Biophys Acta. 2011 Oct; 1807(10):1295-304.

publications Egawa T, Ganesan K, Lin MT, Yu MA, Hosler JP, Yeh SR, Rousseau DL, Gennis RB. Differential effects of glutamate-286 mutations in the aa(3)-type cytochrome c oxidase from Rhodobacter sphaeroides and the cytochrome bo(3) ubiquinol oxidase from Escherichia coli. Biochim Biophys Acta. 2011 Oct; 1807(10):1342-8.

publications Boimel PJ, Cruz C, Segall JE. A functional in vivo screen for regulators of tumor progression identifies HOXB2 as a regulator of tumor growth in breast cancer. Genomics. 2011 Sep; 98(3):164-72.

publications Entenberg D, Wyckoff J, Gligorijevic B, Roussos ET, Verkhusha VV, Pollard JW, Condeelis J. Setup and use of a two-laser multiphoton microscope for multichannel intravital fluorescence imaging. Nat Protoc. 2011 Sep 8; 6(10):1500-20.

publications Carette JE*, Raaben M*, Wong AC*, Herbert AS, Obernosterer G, Mulherkar N, Kuehne AI, Kranzusch PJ, Griffin AM, Ruthel G, Cin PD, Dye JM, Whelan SP, Chandran K, Brummelkamp TR. Ebola virus entry requires the cholesterol transporter Niemann-Pick C1. Nature. 2011 Aug 24; 477(7364):340-3. *Contributed equally.

publications Olabisi OA, Chow CW. Assay for Protein Modification by Poly-ADP-Ribose In Vitro. Methods Mol Biol.2011; 780:47-55.

publications Matsuda S, Tamayev R, D'Adamio L. Increased AβPP Processing in Familial Danish Dementia Patients.J Alzheimers Dis. 2011 Jan 1; 27(2):385-91.

publications Manning EP, Tardiff JC, Schwartz SD. A model of calcium activation of the cardiac thin filament.Biochemistry. 2011 Aug 30; 50(34):7405-13.

publications Briggs SW, Galanopoulou AS. Altered GABA Signaling in Early Life Epilepsies. Neural Plast. 2011; 2011:527605.

publications Roussos ET, Goswami S, Balsamo M, Wang Y, Stobezki R, Adler E, Robinson BD, Jones JG, Gertler FB, Condeelis JS, Oktay MH. Mena invasive (Mena(INV)) and Mena11a isoforms play distinct roles in breast cancer cell cohesion and association with TMEM. Clin Exp Metastasis. 2011 Aug; 28(6):515-27.

publications Roussos ET, Condeelis JS, Patsialou A. Chemotaxis in cancer. Nat Rev Cancer. 2011 Jul 22; 11(8):573-87.

publications Roussos ET, Balsamo M, Alford SK, Wyckoff JB, Gligorijevic B, Wang Y, Pozzuto M, Stobezki R, Goswami S, Segall JE, Lauffenburger DA, Bresnick AR, Gertler FB, Condeelis JS. Mena invasive (MenaINV) promotes multicellular streaming motility and transendothelial migration in a mouse model of breast cancer. J Cell Sci. 2011 Jul 1; 124(Pt 13):2120-31.

publications Smirnova T, Zhou ZN, Flinn RJ, Wyckoff J, Boimel PJ, Pozzuto M, Coniglio SJ, Backer JM, Bresnick AR, Condeelis JS, Hynes NE, Segall JE. Phosphoinositide 3-kinase signaling is critical for ErbB3-driven breast cancer cell motility and metastasis. Oncogene. 2011 Jul 4. doi: 10.1038/onc.2011.275.

publications Keller CJ, Bickel S, Entz L, Ulbert I, Milham MP, Kelly C, Mehta AD. Intrinsic functional architecture predicts electrically evoked responses in the human brain. Proc Natl Acad Sci U S A. 2011 Jun 21; 108(25):10308-13.

publications Wontakal SN, Guo X, Will B, Shi M, Raha D, Mahajan MC, Weissman S, Snyder M, Steidl U, Zheng D, Skoultchi AI. A Large Gene Network in Immature Erythroid Cells Is Controlled by the Myeloid and B Cell Transcriptional Regulator PU.1. PLoS Genet. 2011 Jun; 7(6):e1001392.

publications Sroubek J, McDonald TV. PKA activity at the ER surface is responsible for augmentation of human ether-a-go-go-related gene product (HERG). J Biol Chem. 2011 Jun 17; 286(24):21927-36.

publications Basilio D, Kienker PK, Briggs SW, Finkelstein A. A kinetic analysis of protein transport through the anthrax toxin channel. J Gen Physiol. 2011 Jun; 137(6):521-31.

publications Park H, Ishihara D, Cox D. Regulation of tyrosine phosphorylation in macrophage phagocytosis and chemotaxis. Arch Biochem Biophys. 2011 Jun 15; 510(2):101-11.

publications Cassera MB, Zhang Y, Hazleton KZ, Schramm VL. Purine and Pyrimidine Pathways as Targets in Plasmodium falciparum. Curr Top Med Chem. 2011; 11(16):2103-15.

publications Tamayev R, Matsuda S, Giliberto L, Arancio O, D'Adamio L. APP heterozygosity averts memory deficit in knockin mice expressing the Danish dementia BRI2 mutant. EMBO J. 2011 May 17; 30(12):2501-9.

publications Miller EH, Harrison JS, Radoshitzky SR, Higgins CD, Chi X, Dong L, Kuhn JH, Bavari S, Lai JR, Chandran K. Inhibition of Ebola virus entry by a C-peptide targeted to endosomes. J Biol Chem. 2011 May 6; 286(18):15854-61.

publications Parikh R, Bali M, Akabas MH. Structure of M2 transmembrane segment of GLIC, a prokaryotic Cys-loop receptor homologue from Gloeobacter violaceus, probed by substituted cysteine accessibility. J Biol Chem. 2011 Apr 22; 286(16):14098-109.

publications Raffo E, Coppola A, Ono T, Briggs SW, Galanopoulou AS. A pulse rapamycin therapy for infantile spasms and associated cognitive decline. Neurobiol Dis. 2011 Aug; 43(2):322-9.

publications Khrapunovich-Baine M, Menon V, Huang Yang CP, Northcote PT, Miller JH, Hogue Angeletti R, Fiser A, Horwitz SB, Xiao H. Hallmarks of molecular action of microtubule stabilizing agents: Effects of epothilone B, ixabepilone, peloruside A, and laulimalide on microtubule conformation. J Biol Chem. 2011 Apr 1; 286(13):11765-78.

publications Acosta D, Suzuki M, Connolly D, Thompson RF, Fazzari MJ, Greally JM, Montagna C. DNA methylation changes in murine breast adenocarcinomas allow the identification of candidate genes for human breast carcinogenesis. Mamm Genome. 2011 Apr; 22(3-4):249-59.

publications Bravo-Cordero JJ, Oser M, Chen X, Eddy R, Hodgson L, Condeelis J. A Novel Spatiotemporal RhoC Activation Pathway Locally Regulates Cofilin Activity at Invadopodia. Curr Biol. 2011 Apr 26; 21(8):635-44.

publications Calderon DP, Fremont R, Kraenzlin F, Khodakhah K. The neural substrates of rapid-onset Dystonia-Parkinsonism. Nat Neurosci. 2011 Mar; 14(3):357-65.

publications Chahwan R, Wontakal SN, Roa S. The multidimensional nature of epigenetic information and its role in disease. Discov Med. 2011 Mar; 11(58):233-43.

publications Schlatterer SDTremblay MA, Acker CM, Davies P. Neuronal c-Abl Overexpression Leads to Neuronal Loss and Neuroinflammation in the Mouse Forebrain. J Alzheimers Dis. 2011; 25(1):119-33.

publications Steinberg LJ, Peña JL. Difference in response reliability predicted by spectrotemporal tuning in the cochlear nuclei of barn owls. J Neurosci. 2011 Mar 2; 31(9):3234-42.

publications How PC, Shields D. Tethering function of the caspase cleavage fragment of Golgi protein p115 promotes apoptosis via a p53-dependent pathway. J Biol Chem. 2011 March; 286(10):8565-8576.

publications Choi CH, Schoenfeld BP, Bell AJ, Hinchey P, Kollaros M, Gertner MJ, Woo NH, Tranfaglia MR, Bear MF, Zukin RS, McDonald TV, Jongens TA, McBride SM. Pharmacological reversal of synaptic plasticity deficits in the mouse model of Fragile X syndrome by group II mGluR antagonist or lithium treatment. Brain Res.2011 Mar 22; 1380:106-19.

publications Kaushik S, Bandyopadhyay U, Sridhar S, Kiffin R, Martinez-Vicente M, Kon M, Orenstein SJ, Wong E, Cuervo AM. Chaperone-mediated autophagy at a glance. J Cell Sci. 2011 Feb 15; 124(Pt 4):495-9.

publications Oser M, Dovas A, Cox D, Condeelis J. Nck1 and Grb2 localization patterns can distinguish invadopodia from podosomes. Eur J Cell Biol. 2011 Feb-Mar; 90(2-3):181-8.

publications Gandhi SJ, Zenklusen D, Lionnet T, Singer RH. Transcription of functionally related constitutive genes is not coordinated. Nat Struct Mol Biol. 2011 Jan; 18(1):27–34.

publications Hinchey J, Jeon BY, Alley H, Chen B, Goldberg M, Derrick S, Morris S, Jacobs WR, Porcelli SA, Lee S. Lysine Auxotrophy Combined with Deletion of the SecA2 Gene Results in a Safe and Highly Immunogenic Candidate Live Attenuated Vaccine for Tuberculosis. PLoS One. 2011 Jan 10; 6(1):e15857.

publications Han G, Friedman AJ, Friedman JM. Nitric oxide releasing nanoparticle synthesis and characterization.Methods Mol Biol. 2011; 704:187-95.

publications Eugenin EA, King JEHazleton JE, Major EO, Bennett MV, Zukin RS, Berman JW. Differences in NMDA Receptor Expression During Human Development Determine the Response of Neurons to HIV-Tat-mediated Neurotoxicity. Neurotox Res. 2011 Jan; 19(1):138-48.

publications Bricard G, Venkataswamy MM, Yu KO, Im JS, Ndonye RM, Howell AR, Veerapen N, Illarionov PA, Besra GS, Li Q, Chang YT, Porcelli SA. α-Galactosylceramide Analogs with Weak Agonist Activity for Human iNKT Cells Define New Candidate Anti-Inflammatory Agents. PLoS One. 2010 Dec 17; 5(12):e14374.

publications Pineda JR, Antoniou D, Schwartz SD. Slow Conformational Motions That Favor Sub-picosecond Motions Important for Catalysis. J Phys Chem B. 2010 Dec 9; 114(48):15985-90.

publications Isaac BM*, Ishihara D*, Nusblat LM, Gevrey JC, Dovas A, Condeelis J, Cox D. N-WASP has the ability to compensate for the loss of WASP in macrophage podosome formation and chemotaxis. Exp Cell Res. 2010 Dec 10; 316(20):3406-16. (*contributed equally)

publications Tamayev R, Matsuda S, Fà M, Arancio O, D'Adamio L. Danish dementia mice suggest that loss of function and not the amyloid cascade causes synaptic plasticity and memory deficits. Proc Natl Acad Sci USA. 2010 Nov 30; 107(48):20822-7.

publications Marsden KCShemesh A, Bayer KU, Carroll RC. Selective translocation of Ca2+/calmodulin protein kinase II{alpha} (CaMKII{alpha}) to inhibitory synapses. Proc Natl Acad Sci USA. 2010 Nov 23; 107(47):20559-64.

publications Roussos ET, Wang Y, Wyckoff JB, Sellers RS, Wang W, Li J, Pollard JW, Gertler FB, Condeelis JS. Mena deficiency delays tumor progression and decreases metastasis in polyoma middle-T transgenic mouse mammary tumors. Breast Cancer Res. 2010 Nov 25; 12(6):R101.

publications Liu CY, Besanceney C, Song Y, Kielian M. Pseudorevertants of a Semliki Forest Virus Fusion-Block Mutation Reveal A Critical Interchain Interaction in the Core Trimer. J Virol. 2010 Nov; 84(22):11624-33.

publications Tamayev R, Giliberto L, Li W, d'Abramo C, Arancio O, Vidal R, D'Adamio L. Memory deficits due to familial British dementia BRI2 mutation are caused by loss of BRI2 function rather than amyloidosis. J Neurosci. 2010 Nov 3; 30(44):14915-24.

publications Barbagallo AP, Weldon R, Tamayev R, Zhou D, Giliberto L, Foreman O, D'Adamio L. Tyr in the Intracellular Domain of APP Regulates Amyloidogenic APP Processing In Vivo. PLoS One. 2010 Nov 16; 5(11):e15503.

publications Oser M, Mader CC, Gil-Henn H, Magalhaes M, Bravo-Cordero JJ, Koleske AJ, Condeelis J. Specific tyrosine phosphorylation sites on cortactin regulate Nck1-dependent actin polymerization in invadopodia.J Cell Sci. 2010 Nov 1; 123(Pt 21):3662-73.

publications Peled JU, Sellers RS, Iglesias-Ussel MD, Shin DM, Montagna C, Zhao C, Li Z, Edelmann W, Morse HC 3rd, Scharff MD. Msh6 Protects Mature B Cells from Lymphoma by Preserving Genomic Stability. Am J Pathol. 2010 Nov; 177(5):2597-608.

publications Mahesh S, Saxena A, Qiu X, Perez-Soler R, Zou Y. Intratracheally administered 5-azacytidine is effective against orthotopic human lung cancer xenograft models and devoid of important systemic toxicity. Clin Lung Cancer. 2010 Nov 1; 11(6):405-11.

publications Abboud N, Chow SK, Saylor CJanda A, Ravetch JV, Scharff MD, Casadevall A. A requirement for Fc{gamma}R in antibody-mediated bacterial toxin neutralization. J Exp Med. 2010 Oct 25; 207(11):2395-405.

publications Roberts TK, Eugenin EA, Morgello S, Clements JE, Zink MC, Berman JW. PrPC, the Cellular Isoform of the Human Prion Protein, Is a Novel Biomarker of HIV-Associated Neurocognitive Impairment and Mediates Neuroinflammation. Am J Pathol. 2010 Oct; 177(4):1848-60.

publications Roussos ET, Keckesova Z, Haley JD, Epstein DM, Weinberg RA, Condeelis JS. AACR Special Conference on Epithelial-Mesenchymal Transition and Cancer Progression and Treatment. Cancer Res. 2010 Oct 1; 70(19):7360-4.

publications Mihu MR, Sandkovsky U, Han G, Friedman JM, Nosanchuk JD, Martinez LR. The use of nitric oxide releasing nanoparticles as a treatment against Acinetobacter baumannii in wound infections. Virulence.2010 Oct 27; 1(2):62-7.

publications Chahwan R, Wontakal SN, Roa S. Crosstalk between genetic and epigenetic information through cytosine deamination. Trends Genet. 2010 Oct; 26(10):443-8.

publications Valderramos SG, Scanfeld D, Uhlemann AC, Fidock DA, Krishna S. Investigations into the Role of the Plasmodium falciparum SERCA (PfATP6) L263E Mutation in Artemisinin Action and Resistance. Antimicrob Agents Chemother. 2010 Sep; 54(9):3842-52.

publications Sidyelyeva G, Wegener C, Schoenfeld BP, Bell AJ, Baker NE, McBride SM, Fricker LD. Individual carboxypeptidase D domains have both redundant and unique functions in Drosophila development and behavior. Cell Mol Life Sci. 2010 Sep; 67(17):2991-3004.

publications Zhu H, Suk HY, Yu RY, Brancho D, Olabisi O, Yang TT, Yang XY, Zhang J, Moussaif M, Durand JL, Jelicks LA, Kim JY, Scherer PE, Frank PG, Lisanti MP, Calvert JW, Duranski MR, Lefer DJ, Huston E, Baillie GS, Houslay MD, Molkentin JD, Jin J, Chow CW. Evolutionarily Conserved Role of Calcineurin in Phosphodegron-Dependent Degradation of Phosphodiesterase-4D. Mol Cell Biol. 2010 Sep; 30(18):4379-90.

publications Sudhamsu J, Kabir M, Airola MV, Patel BA, Yeh SR, Rousseau DL, Crane BR. Co-expression of ferrochelatase allows for complete heme incorporation into recombinant proteins produced in E. coli.Protein Expr Purif. 2010 Sep; 73(1):78-82.

publications Chambers EC, Schechter C, Tow A, Torrens L, Kohlieber R, Calderon R. Household density and obesity in young black and white adults. Ethn Dis. 2010 Autumn; 20(4):366-9.

publications Thompson RF, Atzmon G, Gheorghe C, Liang HQ, Lowes C, Greally JM, Barzilai N. Tissue-specific dysregulation of DNA methylation in aging. Aging Cell. 2010 Aug; 9(4):506-18.

publications Monks DC, Jahangir A, Shanske AL, Samanich J, Morrow BE, Babcock M. Mutational analysis of HOXA2 and SIX2 in a Bronx population with isolated microtia. Int J Pediatr Otorhinolaryngol. 2010 Aug; 74(8):878-82.

publications Chen J, Chen K, Sroubek J, Wu ZY, Thomas D, Bian JS, McDonald TV. Post-transcriptional control of HERG potassium channel protein by {alpha}-adrenergic receptor stimulation. Mol Pharmacol. 2010 Aug.; 78:186-197.

publications Muehlbauer SM, Lima H Jr, Goldman DL, Jacobson LS, Rivera J, Goldberg MF, Palladino MA, Casadevall A, Brojatsch J. Proteasome Inhibitors Prevent Caspase-1-Mediated Disease in Rodents Challenged with Anthrax Lethal Toxin. Am J Pathol. 2010 Aug; 177(2):735-43.

publications McBride SM, Choi CH, Schoenfeld BP, Bell AJ, Liebelt DA, Ferreiro D, Choi RJ, Hinchey P, Kollaros M, Terlizzi AM, Ferrick NJ, Koenigsberg E, Rudominer RL, Sumida A, Chiorean S, Siwicki KK, Nguyen HT, Fortini ME, McDonald TV, Jongens TA. Pharmacological and Genetic Reversal of Age-Dependent Cognitive Deficits Attributable to Decreased presenilin Function. J Neurosci. 2010 Jul 14; 30(28):9510-9522.

publications Machleder SQ, Pineda ET, Schwartz SD. On the Origin of the Chemical Barrier and Tunneling in Enzymes. J Phys Org Chem. 2010 Jul 1; 23(7):690-695.

publications Lai CW, Aronson DE, Snapp EL. BiP availability distinguishes states of homeostasis and stress in the endoplasmic reticulum of living cells. Mol Biol Cell. 2010 Jun 15; 21(12):1909-21.

publications King JE, Eugenin EA, Hazleton JE, Morgello S, Berman JW. Mechanisms of HIV-tat-induced phosphorylation of N-Methyl-D-Aspartate receptor subunit 2A in human Primary neurons. Implications for neuroAIDS pathogenesis. Am J Pathol. 2010 Jun; 176(6):2819-30.

publications Peled JU, Yu JJ, Venkatesh J, Bi E, Ding BB, Krupski-Downs M, Shaknovich R, Sicinski P, Diamond B, Scharff MD, Ye BH. Requirement for cyclin D3 in germinal center formation and function. Cell Res. 2010 Jun; 20(6):631-46.

publications Roa S, Li Z, Peled JU, Zhao C, Edelmann W, Scharff MD. MSH2/MSH6 complex promotes error-free repair of AID-induced dU:G mispairs as well as error-prone hypermutation of A:T sites. PLoS One. 2010 Jun 17; 5(6):e11182.

publications Choi CH, McBride SM, Schoenfeld BP, Liebelt DA, Ferreiro D, Ferrick NJ, Hinchey P, Kollaros M, Rudominer RL, Terlizzi AM, Koenigsberg E, Wang Y, Sumida A, Nguyen HT, Bell AJ, McDonald TV, Jongens TA. Age-dependent cognitive impairment in a Drosophila Fragile X model and its pharmacological rescue.Biogerontology. 2010 Jun; 11(3):347-62.

publications Riegelhaupt PM*Frame IJ*, Akabas MH. Transmembrane segment 11 appears to line the purine permeation pathway of the Plasmodium falciparum equilibrative nucleoside transporter 1 (PfENT1). J Biol Chem. 2010 May 28; 285(22):17001-10. (*contributed equally)

publications Palacios-Prado N, Briggs SW, Skeberdis VA, Pranevicius M, Bennett MV, Bukauskas FF. pH-dependent modulation of voltage gating in connexin45 homotypic and connexin45/connexin43 heterotypic gap junctions. Proc Natl Acad Sci U S A. 2010 May 25; 107(21):9897-902.

publications Weiss SA, Faber DS. Field effects in the CNS play functional roles. Front Neural Circuits. 2010 May 18; 4:15.

publications Valderramos SG, Valderramos JC, Musset L, Purcell LA, Mercereau-Puijalon O, Legrand E, Fidock DA. Identification of a mutant PfCRT-mediated chloroquine tolerance phenotype in Plasmodium falciparum.PLoS Pathog. 2010 May 13; 6(5):e1000887.

publications Rice R, Guinto P, Dowell-Martino C, He H, Hoyer K, Krenz M, Robbins J, Ingwall JS, Tardiff JC. Cardiac Myosin Heavy Chain Isoform Exchange Alters the Phenotype of cTnT-Related Cardiomyopathies in Mouse Hearts. J Mol Cell Cardiol. 2010 May; 48(5):979-88.

publications Gross DA, Snapp EL, Silver DL. Structural insights into triglyceride storage mediated by fat storage-inducing transmembrane (FIT) protein 2. PLoS One. 2010 May 24; 5(5):e10796.

publications Thompson RF, Fazzari MJ, Niu H, Barzilai N, Simmons RA, Greally JM. Experimental IUGR induces alterations in DNA methylation and gene expression in pancreatic islets of rats. J Biol Chem. 2010 May. 285(20):15111-15118.

publications Papetti M, Wontakal SN, Stopka T, Skoultchi AI. GATA-1 directly regulates p21 gene expression during erythroid differentiation. Cell Cycle. 2010 May 15; 9(10):1972-80.

publications Banerjee P, Schoenfeld BP, Bell AJ, Choi CH, Bradley MP, Hinchey P, Kollaros M, Park JH, McBride SM, Dockendorff TC. Short- and long-term memory are modulated by multiple isoforms of the fragile X mental retardation protein. J Neurosci. 2010 May 12; 30(19):6782-92.

publications Martinez LR, Mihu MR, Tar M, Cordero RJ, Han G, Friedman AJ, Friedman JM, Nosanchuk JD. Demonstration of Antibiofilm and Antifungal Efficacy of Chitosan against Candidal Biofilms, Using an In Vivo Central Venous Catheter Model. J Infect Dis. 2010 May 1; 201(9):1436-40.

publications Thompson RF, Fazzari MJ, Greally JM. Experimental approaches to the study of epigenomic dysregulation in ageing. Exp Gerontol. 2010 Apr; 45(4):255-68.

publications Yu MA, Egawa T, Yeh SR, Rousseau DL, Gerfen GJ. EPR characterization of ascorbyl and sulfur dioxide anion radicals trapped during the reaction of bovine Cytochrome c Oxidase with molecular oxygen. J Magn Reson. 2010 Apr; 203(2):213-219.

publications Kon M, Cuervo AM. Chaperone-mediated Autophagy in Health and Disease. FEBS Lett. 2010 Apr 2; 584(7):1399-1404.

publications Kuokkanen S, Chen B, Ojalvo L, Benard L, Santoro N, Pollard JW. Genomic Profiling of MicroRNAs and Messenger RNAs Reveals Hormonal Regulation in MicroRNA expression in Human Endometrium. Biol Reprod. 2010 Apr; 82(4):791-801.

publications Janda A, Casadevall A. Circular Dichroism reveals evidence of coupling between immunoglobulin constant and variable region secondary structure. Mol Immunol. 2010 Apr; 47(7-8):1421-5.

publications Das BC, Mahalingam SM, Panda L, Wang B, Campbell P, Evans T. Design and Synthesis of Potential New Apoptosis Agents: Hybrid Compounds Containing Perillyl Alcohol and New Constrained Retinoids.Tetrahedron Lett. 2010 Mar 17; 51(11):1462-1466.

publications Thompson RF, Einstein FH. Epigenetic Basis for Fetal Origins of Age-Related Disease. J Womens Health (Larchmt). 2010 Mar; 19(3):581-7.

publications Martinez LR, Mihu MR, Han G, Frases S, Cordero RJ, Casadevall A, Friedman AJ, Friedman JM, Nosanchuk JD. The use of chitosan to damage Cryptococcus neoformans biofilms. Biomaterials. 2010 Feb; 31(4):669-79.

publications Choe KS, Ujhelly O, Wontakal SN, Skoultchi AI. PU.1 directly regulates cdk6 gene expression, linking the cell proliferation and differentiation programs in erythroid cells. J Biol Chem. 2010 Jan 29; 285(5):3044-52.

publications Tremblay MA, Acker CM, Davies P. Tau Phosphorylated at Tyrosine 394 is Found in Alzheimer's Disease Tangles and Can Be a Product of the Abl-Related Kinase, Arg. J Alzheimers Dis. 2010; 19(2):721-33.

publications Riegelhaupt PM, Cassera MB, Fröhlich RF, Hazleton KZ, Hefter JJ, Schramm VL, Akabas MH. Transport of Purines and Purine Salvage Pathway Inhibitors by the Plasmodium falciparum Equilibrative Nucleoside Transporter PfENT1. Mol Biochem Parasitol. 2010 Jan; 169(1):40-9.

publications Chao JA, Patskovsky Y, Patel V, Levy M, Almo SC, Singer RH. ZBP1 recognition of beta-actin zipcode induces RNA looping. Genes Dev. 2010 Jan 15; 24(2):148-58.


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