Medical Scientist Training Program (MSTP)

Student Publications

MSTP students graduating in the past five years published an average of 5.2 papers per student, 2.7 first author papers per student. Thus, the students were highly productive in their thesis research. 48% of these papers involved collaborations between the laboratories of two or more Einstein faculty members. This demonstrates the highly collaborative nature of the Einstein faculty.

Recent publications by MSTP students:

publications Khan S, Kelly L. Multiclass Disease Classification from Microbial Whole-Community Metagenomes. Pac Symp Biocomput. 2020; 25:55-66.

publications Malonis RJ, Lai JR, Vergnolle O. Peptide-Based Vaccines: Current Progress and Future Challenges. Chem Rev. 2019 Dec 5. doi: 10.1021/acs.chemrev.9b00472. [Epub ahead of print].

publications Diacou R, Bhansali P, Liu W. Three-Dimensional Culture of Mouse Eyecups. Methods Mol Biol. 2020; 2092:35-43.

publications Mayoral J, Di Cristina M, Carruthers VB, Weiss LM. Toxoplasma gondii: Bradyzoite Differentiation In Vitro and In Vivo. Methods Mol Biol. 2020; 2071:269-282.

publications Savage T, Pandey S, Guha C. Post-ablation modulation after single high-dose radiation therapy improves tumor control via enhanced immunomodulation. Clin Cancer Res. 2019 Nov 22. pii: clincanres.3518.2018. doi: 10.1158/1078-0432.CCR-18-3518. [Epub ahead of print].

publications Kabarriti R, Brodin NP, Yaffe H, Barahman M, Koba WR, Liu L, Asp P, Tomé WA, Guha C. Non-Invasive Targeted Hepatic Irradiation and SPECT/CT Functional Imaging to Study Radiation-Induced Liver Damage in Small Animal Models. Cancers (Basel). 2019 Nov 15; 11(11). pii: E1796.

publications Klein ME, Younts TJ, Cobo CF, Buxbaum AR, Aow J, Erdjument-Bromage H, Richard S, Malinow R, Neubert TA, Singer RH, Castillo PE, Jordan BA. Sam68 Enables Metabotropic Glutamate Receptor-Dependent LTD in Distal Dendritic Regions of CA1 Hippocampal Neurons. Cell Rep. 2019 Nov 12; 29(7):1789-1799.e6.

publications Quiroz JA, Malonis RJ, Thackray LB, Cohen CA, Pallesen J, Jangra RK, Brown RS, Hofmann D, Holtsberg FW, Shulenin S, Nyakatura EK, Durnell LA, Rayannavar V, Daily JP, Ward AB, Aman MJ, Dye JM, Chandran K, Diamond MS, Kielian M, Lai JR. Human monoclonal antibodies against chikungunya virus target multiple distinct epitopes in the E1 and E2 glycoproteins. PLoS Pathog. 2019 Nov 7; 15(11):e1008061.

publications Murphy A, Barbaro J, Martínez-Aguado P, Chilunda V, Jaureguiberry-Bravo M, Berman JW. The Effects of Opioids on HIV Neuropathogenesis. Front Immunol. 2019 Oct 18; 10:2445.

publications John P, Wei Y, Liu W, Du M, Guan F, Zang X. The B7x Immune Checkpoint Pathway: From Discovery to Clinical Trial. Trends Pharmacol Sci. 2019 Oct 30. pii: S0165-6147(19)30226-3 doi: 10.1016/ [Epub ahead of print].

publications Skalina KA, Singh S, Chavez CG, Macian F, Guha C. Low Intensity Focused Ultrasound (LOFU)-mediated Acoustic Immune Priming and Ablative Radiation Therapy for in situ Tumor Vaccines. Sci Rep. 2019 Oct 29; 9(1):15516.

publications Iqbal N, Zhu L, Chua SC Jr. Neuronal Cell Cycle Events Link Caloric Intake to Obesity. Trends Endocrinol Metab. 2019 Oct 16. pii: S1043-2760(19)30185-7. doi: 10.1016/j.tem.2019.09.001. [Epub ahead of print].

publications Shrestha R, Fajardo E, Gil N, Fidelis K, Kryshtafovych A, Monastyrskyy B, Fiser A. Assessing the accuracy of contact predictions in CASP13. Proteins. 2019 Oct 6. doi: 10.1002/prot.25819. [Epub ahead of print].

publications Ghias MH, Johnston AD, Kutner AJ, Micheletti RG, Hosgood HD, Cohen SR. High-dose, high-frequency infliximab: A novel treatment paradigm for hidradenitis suppurativa. J Am Acad Dermatol. 2019 Oct 4. pii: S0190-9622(19)32820-8. doi: 10.1016/j.jaad.2019.09.071. [Epub ahead of print].

publications Symonds RM, Zhou JW, Cole SL, Brace KM, Sussman ES. Cognitive resources are distributed among the entire auditory landscape in auditory scene analysis. Psychophysiology. 2019 Oct; 2:e13487. doi: 10.1111/psyp.13487. [Epub ahead of print].

publications Biswas J, Patel VL, Bhaskar V, Chao JA, Singer RH, Eliscovich C. The structural basis for RNA selectivity by the IMP family of RNA-binding proteins. Nat Commun. 2019 Sep 30; 10(1):4440.

publications Hasenoehrl EJ, Rae Sajorda D, Berney-Meyer L, Johnson S, Tufariello JM, Fuhrer T, Cook GM, Jacobs WR Jr, Berney M. Derailing the aspartate pathway of Mycobacterium tuberculosis to eradicate persistent infection. Nat Commun. 2019 Sep 16; 10(1):4215.

publications Brace KM, Lee WW, Cole PD, Sussman ES. Childhood leukemia survivors exhibit deficiencies in sensory and cognitive processes, as reflected by event-related brain potentials after completion of curative chemotherapy: A preliminary investigation. J Clin Exp Neuropsychol. 2019 Oct; 41(8):814-831.

publications Huang MW, Stock AD, Mike EV, Herlitz L, Kolbeck R, Putterman C. Anti-IFNAR treatment does not reverse neuropsychiatric disease in MRL/lpr lupus mice. Lupus. 2019 Aug 31:961203319872265. doi: 10.1177/0961203319872265. [Epub ahead of print].

publications Han B, Ma Y, Tu V, Tomita T, Mayoral J, Williams T, Horta A, Huang H, Weiss LM. Microsporidia Interact with Host Cell Mitochondria via Voltage-Dependent Anion Channels Using Sporoplasm Surface Protein 1. MBio. 2019 Aug 20; 10(4). pii: e01944-19.

publications Willcockson MA, Taylor SJ, Ghosh S, Healton SE, Wheat JC, Wilson TJ, Steidl U, Skoultchi AI. Runx1 promotes murine erythroid progenitor proliferation and inhibits differentiation by preventing Pu.1 downregulation. Proc Natl Acad Sci U S A. 2019 Aug 20. pii: 201901122. doi: 10.1073/pnas.1901122116. [Epub ahead of print].

publications Johnston AD, Simões-Pires CA, Suzuki M, Greally JM. High-efficiency genomic editing in Epstein-Barr virus-transformed lymphoblastoid B cells using a single-stranded donor oligonucleotide strategy. Commun Biol. 2019 Aug 14; 2:312.

publications Salloum G, Jakubik CT, Erami Z, Heitz SD, Bresnick AR, Backer JM. PI3Kβ is selectively required for growth factor-stimulated macropinocytosis. J Cell Sci. 2019 Aug 13. pii: jcs.231639. doi: 10.1242/jcs.231639. [Epub ahead of print].

publications Carbonell AU, Cho CH, Tindi JO, Counts PA, Bates JC, Erdjument-Bromage H, Cvejic S, Iaboni A, Kvint I, Rosensaft J, Banne E, Anagnostou E, Neubert TA, Scherer SW, Molholm S, Jordan BA. Haploinsufficiency in the ANKS1B gene encoding AIDA-1 leads to a neurodevelopmental syndrome. Nat Commun. 2019 Aug 6; 10(1):3529.

publications Johnston AD, Simões-Pires CA, Thompson TV, Suzuki M, Greally JM. Functional genetic variants can mediate their regulatory effects through alteration of transcription factor binding. Nat Commun. 2019 Aug 2; 10(1):3472.

publications Rao L, Berger F, Nicholas MP, Gennerich A. Molecular mechanism of cytoplasmic dynein tension sensing. Nat Commun. 2019 Jul 26; 10(1):3332.

publications Yakubu RR, Nieves E, Weiss LM. The Methods Employed in Mass Spectrometric Analysis of Posttranslational Modifications (PTMs) and Protein-Protein Interactions (PPIs). Adv Exp Med Biol. 2019; 1140:169-198.

publications Andriani GA, Maggi E, Piqué D, Zimmerman SE, Lee M, Quispe-Tintaya W, Maslov A, Campisi J, Vijg J, Mar JC, Montagna C. A direct comparison of interphase FISH versus low-coverage single cell sequencing to detect aneuploidy reveals respective strengths and weaknesses. Sci Rep. 2019 Jul 19; 9(1):10508.

publications Hoogenboom WS, Rubin TG, Ye K, Cui MH, Branch KC, Liu J, Branch CA, Lipton ML.Diffusion Tensor Imaging of the Evolving Response to Mild Traumatic Brain Injury in Rats. J Exp Neurosci. 2019 Jul 5; 13:1179069519858627.

publications Gil N, Fajardo EJ, Fiser A. Discovery of Receptor-Ligand Interfaces in the Immunoglobulin Superfamily. Proteins. 2019 Jul 12. doi: 10.1002/prot.25778. [Epub ahead of print].

publications Fels JM, Spence JS, Bortz RH 3rd, Bornholdt ZA, Chandran K. A Hyperstabilizing Mutation in the Base of the Ebola Virus Glycoprotein Acts at Multiple Steps To Abrogate Viral Entry. MBio. 2019 Jul 9; 10(4). pii: e01408-19. doi: 10.1128/mBio.01408-19.

publications Mazori AY, Maron MI, Osterbur ML Badhey, Santos D, Marco VF, Lin J, Cortijo A, Nosal S, Schoenbaum E. Enhancing Medical Student-Interpreter Collaboration in an Urban Free Clinic. Fam Med. 2019 Jul; 51(7):593-597.

publications Cai D, Khor S. "Hypothalamic Microinflammation" Paradigm in Aging and Metabolic Diseases. Cell Metab. 2019 Jul 2; 30(1):19-35.

publications Schloss J, Ali R, Babad J, Guerrero-Ros I, Pongsachai J, He LZ, Keler T, DiLorenzo TP. Development and Characterization of a Preclinical Model for the Evaluation of CD205-Mediated Antigen Delivery Therapeutics in Type 1 Diabetes. Immunohorizons. 2019 Jun 26; 3(6):236-253.

publications Piqué DG, Andriani GA, Maggi E, Zimmerman SE, Greally JM, Montagna C, Mar JC. Aneuvis: web-based exploration of numerical chromosomal variation in single cells. BMC Bioinformatics. 2019 Jun 17; 20(1):336.

publications Rubin TG, Lipton ML. Sex Differences in Animal Models of Traumatic Brain Injury. J Exp Neurosci. 2019 May 13;13:1179069519844020.

publications Piszczatowski RT, Steidl U. Aurora Kinase A inhibition: A mega-hit for myelofibrosis therapy? Clin Cancer Res. 2019 Jun 13. pii: clincanres.1481.2019. doi: 10.1158/1078-0432.CCR-19-1481. [Epub ahead of print].

publications Stock AD, Der E, Gelb S, Huang M, Weidenheim K, Ben-Zvi A, Putterman C. Tertiary lymphoid structures in the choroid plexus in neuropsychiatric lupus. JCI Insight. 2019 Jun 6;4(11). pii: 124203. doi: 10.1172/jci.insight.124203. eCollection 2019 Jun 6.

publications Brace KM, Lee WW, Cole PD, Sussman ES. Childhood leukemia survivors exhibit deficiencies in sensory and cognitive processes, as reflected by event-related brain potentials after completion of curative chemotherapy: A preliminary investigation. J Clin Exp Neuropsychol. 2019 Jun 3:1-18. doi: 10.1080/13803395.2019.1623865. [Epub ahead of print].

publications Wilson TJ, Foxe JJ. Cross-Frequency Coupling of Alpha Oscillatory Power to the Entrainment Rhythm of a Spatially Attended Input Stream. Cogn Neurosci. 2019 Jun 3. doi: 10.1080/17588928.2019.1627303. [Epub ahead of print].

publications Hanoun M, Arnal-Estapé A, Maryanovich M, Zahalka AH, Bergren SK, Chua CW, Leftin A, Brodin PN, Shen MM, Guha C, Frenette PS. Nestin(+)NG2(+) Cells Form a Reserve Stem Cell Population in the Mouse Prostate. Stem Cell Reports. 2019 May 10. pii: S2213-6711(19)30141-9. doi: 10.1016/j.stemcr.2019.04.019. [Epub ahead of print].

publications Tu V, Mayoral J, Sugi T, Tomita T, Han B, Ma YF, Weiss LM. Enrichment and Proteomic Characterization of the Cyst Wall from In Vitro Toxoplasma gondii Cysts. MBio. 2019 Apr 30;10(2). pii: e00469-19. doi: 10.1128/mBio.00469-19.

publications Nakahara F, Borger DK, Wei Q, Pinho S, Maryanovich M, Zahalka AH, Suzuki M, Cruz CD, Wang Z, Xu C, Boulais PE, Ma'ayan A, Greally JM, Frenette PS. Engineering a haematopoietic stem cell niche by revitalizing mesenchymal stromal cells. Nat Cell Biol. 2019 Apr 15. doi: 10.1038/s41556-019-0308-3. [Epub ahead of print].

publications Milano CR, Holloway JK, Zhang Y, Jin B, Smith C, Bergman A, Edelmann W, Cohen PE. Mutation of the ATPase Domain of MutS Homolog-5 (MSH5) Reveals a Requirement for a Functional MutSγ Complex for All Crossovers in Mammalian Meiosis. G3 (Bethesda). 2019 Apr 3. pii: g3.400074.2019. doi: 10.1534/g3.119.400074. [Epub ahead of print].

publications Hawk CS, Coelho C, Oliveira DSL, Paredes V, Albuquerque P, Bocca AL, Correa Dos Santos A, Rusakova V, Holemon H, Silva-Pereira I, Felipe MSS, Yagita H, Nicola AM, Casadevall A. Integrin β1 Promotes the Interaction of Murine IgG3 with Effector Cells. J Immunol. 2019 Mar 20. pii: ji1701795. doi: 10.4049/jimmunol.1701795. [Epub ahead of print].

publications Piqué DG, Montagna C, Greally JM, Mar JC. A novel approach to modelling transcriptional heterogeneity identifies the oncogene candidate CBX2 in invasive breast carcinoma. Br J Cancer. 2019 Mar 1. doi: 10.1038/s41416-019-0387-8. [Epub ahead of print].

publications Barahman M, Asp P, Roy-Chowdhury N, Kinkhabwala M, Roy-Chowdhury J, Kabarriti R, Guha C. Hepatocyte Transplantation: Quo Vadis? Int J Radiat Oncol Biol Phys. 2019 Mar 15; 103(4):922-934.

publications Veenstra M, Byrd DA, Inglese M, Buyukturkoglu K, Williams DW, Fleysher L, Li M, Gama L, León-Rivera R, Calderon TM, Clements JE, Morgello S, Berman JW. CCR2 on Peripheral Blood CD14(+)CD16(+) Monocytes Correlates with Neuronal Damage, HIV-Associated Neurocognitive Disorders, and Peripheral HIV DNA: reseeding of CNS reservoirs? J Neuroimmune Pharmacol. 2019 Mar; 14(1):120-133.

publications Schwartz N, Stock AD, Putterman C. Neuropsychiatric lupus: new mechanistic insights and future treatment directions. Nat Rev Rheumatol. 2019 Mar; 15(3):137-152.

publications Nishtala SN*, Arora A*, Reyes J, Akabas MH. Accessibility of substituted cysteines in TM2 and TM10 transmembrane segments in the Plasmodium falciparum equilibrative nucleoside transporter PfENT1. J Biol Chem. 2019; 294:1924-1935. (* contributed equally).

publications Lee BS, Kalia NP, Jin XEF, Hasenoehrl EJ, Berney M, Pethe K. Inhibitors of energy metabolism interfere with antibiotic-induced death in mycobacteria. J Biol Chem. 2019 Feb 8; 294(6):1936-1943.

publications Byrd EA, Kielian M. The Alphavirus E2 Membrane-Proximal Domain Impacts Capsid Interaction and Glycoprotein Lattice Formation. J Virol. 2019 Feb 5; 93(4). pii: e01881-18.

publications Wang Z, Khor S, Cai D. Age-dependent decline of hypothalamic HIF2α in response to insulin and its contribution to advanced age-associated metabolic disorders in mice. J Biol Chem. 2019 Feb 1. pii: jbc.RA118.005429. doi: 10.1074/jbc.RA118.005429. [Epub ahead of print].

publications Tang LT, Diaz-Balzac CA, Rahman M, Ramirez-Suarez NJ, Salzberg Y, Lázaro-Peña MI, Bülow HE. TIAM-1/GEF can shape somatosensory dendrites independently of its GEF activity by regulating F-actin localization. Elife. 2019 Jan 29; 8. pii: e38949.

publications Gil N, Fiser A. The choice of sequence homologs included in multiple sequence alignments has a dramatic impact on evolutionary conservation analysis. Bioinformatics. 2019 Jan 1; 35(1):12-19

publications Hanna SJ, McCoy-Simandle K, Leung E, Genna A, Condeelis J, Cox D. Tunneling nanotubes, a novel mode of tumor cell-macrophage communication in tumor cell invasion. J Cell Sci. 2019 Jan 18. pii: jcs.223321. doi: 10.1242/jcs.223321. [Epub ahead of print].

publications Barahman M, Zhang W, Yaffe Harris H, Aiyer A, Kabarriti R, Kinkhabwala M, Roy-Chowdhury N, Beck AP, Scanlan TS, Roy-Chowdhury J, Asp P, Guha C. Radiation-primed hepatocyte transplantation in murine monogeneic dyslipidemia normalizes cholesterol and prevents atherosclerosis. J Hepatol. 2019 Jan 14. pii: S0168-8278(19)30022-4. doi: 10.1016/j.jhep.2019.01.010. [Epub ahead of print].

publications Wec AZ, Bornholdt ZA, He S, Herbert AS, Goodwin E, Wirchnianski AS, Gunn BM, Zhang Z, Zhu W, Liu G, Abelson DM, Moyer CL, Jangra RK, James RM, Bakken RR, Bohorova N, Bohorov O, Kim DH, Pauly MH, Velasco J, Bortz RH 3rd, Whaley KJ, Goldstein T, Anthony SJ, Alter G, Walker LM, Dye JM, Zeitlin L, Qiu X, Chandran K. Development of a Human Antibody Cocktail that Deploys Multiple Functions to Confer Pan-Ebolavirus Protection. Cell Host Microbe. 2019 Jan 9; 25(1):39-48.

publications Weiss CN, Ito K. microRNA-22 promotes megakaryocyte differentiation through repression of its target, GFI1. Blood Adv. 2019 Jan 8; 3(1):33-46.

publications Mike EV, Makinde HM, Gulinello M, Vanarsa K, Herlitz L, Gadhvi G, Winter DR, Mohan C, Hanly JG, Mok CC, Cuda CM, Putterman C. Lipocalin-2 is a pathogenic determinant and biomarker of neuropsychiatric lupus. J Autoimmun. 2019 Jan; 96:59-73.

publications Diacou R, Zhao Y, Zheng D, Cvekl A, Liu W. Six3 and Six6 Are Jointly Required for the Maintenance of Multipotent Retinal Progenitors through Both Positive and Negative Regulation. Cell Rep. 2018 Nov 27;25(9):2510-2523.

publications Rubin TG*, Catenaccio E*, Fleysher R, Hunter LE, Lubin N, Stewart WF, Kim M, Lipton RB, Lipton ML. MRI-defined White Matter Microstructural Alteration Associated with Soccer Heading Is More Extensive in Women than Men. Radiology. 2018 Nov; 289(2):478-486. (*contributed equally)

publications Hunter LE, Lubin N, Glassman N, Xue X, Spira M, Lipton ML. Comparing Region of Interest vs. Voxel-Wise Diffusion Tensor Imaging Analytic Methods in Mild and Moderate Traumatic Brain Injury: A Systematic Review and Meta-Analysis. J Neurotrauma. 2018 Oct 30. doi: 10.1089/neu.2018.5838. [Epub ahead of print].

publications Mao SPH, Park M, Cabrera RM, Christin JR, Karagiannis GS, Oktay MH, Zaiss DMW, Abrams SI, Guo W, Condeelis JS, Kenny PA, Segall JE. Loss of amphiregulin reduces myoepithelial cell coverage of mammary ducts and alters breast tumor growth. Breast Cancer Res. 2018 Oct 26; 20(1):131.

publications Suzuki M, Liao W, Wos F, Johnston AD, DeGrazia J, Ishii J, Bloom T, Zody MC, Germer S, Greally JM. Whole-genome bisulfite sequencing with improved accuracy and cost. Genome Res. 2018 Sep; 28(9):1364-1371.

publications Mike EV, Makinde HM, Der E, Stock A, Gulinello M, Gadhvi GT, Winter DR, Cuda CM, Putterman C. Neuropsychiatric Systemic Lupus Erythematosus Is Dependent on Sphingosine-1-Phosphate Signaling. Front Immunol. 2018 Sep 26; 9:2189.

publications Zhang Y, Zvi YS, Batko B, Zaphiros N, O'Donnell EF, Wang J, Sato K, Yang R, Geller DS, Koirala P, Zhang W, Du X, Piperdi S, Liu Y, Zheng D, Roth M, Gill J, Zhang J, Ren T, Gorlick R, Zi X, Hoang BH. Down-regulation of Skp2 expression inhibits invasion and lung metastasis in osteosarcoma. Sci Rep. 2018 Sep 24;8(1):14294.

publications Iqbal NJ, Lu Z, Liu SM, Schwartz GJ, Chua S Jr, Zhu L. Cyclin-dependent kinase 4 is a preclinical target for diet-induced obesity. JCI Insight. 2018 Sep 6; 3(17). pii: 123000. doi: 10.1172/jci.insight.123000

publications Skalina KA, Ramesh M. A case of allergic contact dermatitis caused by Disperse Blue dye in ultrasound gel. Contact Dermatitis. 2018 Sep; 79(3):175-176.

publications Bertalovitz AC*, Osterbur Badhey ML*, McDonald TV. Synonymous nucleotide modification of the KCNH2 gene affects both mRNA characteristics and translation of the encoded hERG ion channel. J Biol Chem. 2018 Aug 3; 293(31):12120-12136. (*contributed equally).

publications Biswas J, Liu Y, Singer RH, Wu B. Fluorescence Imaging Methods to Investigate Translation in Single Cells. Cold Spring Harb Perspect Biol. 2018 Aug 6. pii: a032722. doi: 10.1101/cshperspect.a032722. [Epub ahead of print].

publications Mocholi E, Dowling SD, Botbol Y, Gruber RC, Ray AK, Vastert S, Shafit-Zagardo B, Coffer PJ, Macian F. Autophagy Is a Tolerance-Avoidance Mechanism that Modulates TCR-Mediated Signaling and Cell Metabolism to Prevent Induction of T Cell Anergy. Cell Rep. 2018 Jul 31; 24(5):1136-1150.

publications Hunter LE, Ifrah C, Zimmerman ME, Kim M, Lipton RB, Stewart WF, Lipton ML. Heading and unintentional head impacts have opposing associations with Patient Reported Outcomes in amateur soccer players. Res Sports Med. 2018 Jul; 13:1-11.

publications Kaufman OH, Lee K, Martin M, Rothhämel S, Marlow FL. rbpms2 functions in Balbiani body architecture and ovary fate. PLoS Genet. 2018 Jul 5; 14(7):e1007489.

publications Gelb S, Stock AD, Anzi S, Putterman C, Ben-Zvi A. Mechanisms of neuropsychiatric lupus: The relative roles of the blood-cerebrospinal fluid barrier versus blood-brain barrier. J Autoimmun. 2018 Jul; 91:34-44.

publications Wheat JC, Steidl U. Linking histone methylation, transcription rates, and stem cell robustness. Haematologica. 2018 Jul; 103(7):1093.

publications Kong Y, Berko ER, Marckette A, Maqbool SB, Simões-Pires CA, Kronn DF, Ye QK, Suzuki M, Auton A, Greally J. Detecting, quantifying, and discriminating the mechanism of mosaic chromosomal aneuploidies using MAD-seq. Genome Res. 2018 Jul; 28(7):1039-1052.

publications Maryanovich M, Zahalka AH, Pierce H, Pinho S, Nakahara F, Asada N, Wei Q, Wang X, Ciero P, Xu J, Leftin A, Frenette PS. Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche. Nat Med. 2018 Jun; 24(6):782-791.

publications Keller CJ, Huang Y, Herrero JL, Fini ME, Du V, Lado FA, Honey CJ, Mehta AD. Induction and Quantification of Excitability Changes in Human Cortical Networks. J Neurosci. 2018 Jun 6; 38(23):5384-5398.

publications Wu Y, Wang Z, Cai P, Jiang T, Li Y, Yuan Y, Li R, Khor S, Lu Y, Wang J, Chen D, Zeng Q, Zhong R, Zhang H, Lin Y, Li X, Xiao J. Dual Delivery of bFGF- and NGF-Binding Coacervate Confers Neuroprotection by Promoting Neuronal Proliferation. Cell Physiol Biochem. 2018 Jun 12; 47(3):948-956.

publications Schloss J, Ali R, Racine JJ, Chapman HD, Serreze DV, DiLorenzo TP. HLA-B*39:06 Efficiently Mediates Type 1 Diabetes in a Mouse Model Incorporating Reduced Thymic Insulin Expression. J Immunol. 2018 May 15; 200(10):3353-3363.

publications Kerner-Rossi M, Gulinello M, Walkley S, Dobrenis K. Pathobiology of Christianson Syndrome: Linking Disrupted Endosomal-Lysosomal Function with Intellectual Disability and Sensory Impairments. Neurobiol Learn Mem. 2018 May 14. pii: S1074-7427(18)30114-X. doi: 10.1016/j.nlm.2018.05.004. [Epub ahead of print].

publications Feng Y, Liu J, Guo W, Guan Y, Xu H, Guo Q, Song X, Yi F, Liu T, Zhang W, Dong X, Cao LL, O'Rourke BP, Cao L. Atg7 inhibits Warburg effect by suppressing PKM2 phosphorylation resulting reduced epithelial-mesenchymal transition. Int J Biol Sci. 2018 May 12; 14(7):775-783.

publications Oda M, Wakabayashi S, Wijetunga NA, Yuasa S, Enomoto H, Kaneda R, Yoon SH, Mittal N, Jing Q, Suzuki M, Greally JM, Fukuda K, Makino S. Selective modulation of local linkages between active transcription and oxidative demethylation activity shapes cardiomyocyte-specific gene-body epigenetic status in mice. BMC Genomics. 2018 May 10; 19(1):349.

publications Celestrin K, Díaz-Balzac C, Tang LTH, Ackley BD, Bülow HE. Four specific Ig domains in UNC-52/Perlecan function with NID-1/Nidogen during dendrite morphogenesis in Caenorhabditis elegans. Development. 2018 May 14; 145(10). pii: dev158881. doi: 10.1242/dev.158881.

publications Powell Gray B, Kelly L, Ahrens DP, Barry AP, Kratschmer C, Levy M, Sullenger BA. Tunable cytotoxic aptamer-drug conjugates for the treatment of prostate cancer. Proc Natl Acad Sci U S A. 2018 May 1; 115(18):4761-4766.

publications Chen Y, Zheng Z, Wang J, Tang C, Khor S, Chen J, Chen X, Zhang Z, Tang Q, Wang C, Lou Y, Wang Z, Xiao J, Wang X. Berberine suppresses apoptosis and extracellular matrix (ECM) degradation in nucleus pulposus cells and ameliorates disc degeneration in a rodent model. Int J Biol Sci. 2018 Apr 30; 14(6):682-692.

publications Gil N, Fiser A. Identifying Functionally Informative Evolutionary Sequence Profiles. Bioinformatics. 2018 Apr 15; 34(8):1278-1286.

publications Carvajal LA, Neriah DB, Senecal A, Benard L, Thiruthuvanathan V, Yatsenko T, Narayanagari SR, Wheat JC, Todorova TI, Mitchell K, Kenworthy C, Guerlavais V, Annis DA, Bartholdy B, Will B, Anampa JD, Mantzaris I, Aivado M, Singer RH, Coleman RA, Verma A, Steidl U. Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia. Sci Transl Med. 2018 Apr 11;10(436). pii: eaao3003. doi: 10.1126/scitranslmed.aao3003.

publications Cabrera RM, Mao SPH, Surve CR, Condeelis JS, Segall JE. A novel neuregulin - jagged1 paracrine loop in breast cancer transendothelial migration. Breast Cancer Res. 2018 Apr 10; 20(1):24.

publications Nosanchuk JD, Jeyakumar A, Ray A, Revskaya E, Jiang Z, Bryan RA, Allen KJH, Jiao R, Malo ME, Gómez BL, Morgenstern A, Bruchertseifer F, Rickles D, Thornton GB, Bowen A, Casadevall A, Dadachova E. Structure-function analysis and therapeutic efficacy of antibodies to fungal melanin for melanoma radioimmunotherapy. Sci Rep. 2018 Apr 3; 8(1):5466.

publications Dowling SD, Macian F. Autophagy and T cell metabolism. Cancer Lett. 2018 Apr 10; 419:20-26.

publications Manning EP, Mishall PL, Weidmann MD, Flax H, Lan S, Erlich M, Burton WB, Olson TR, Downie SA. Early and prolonged opportunities to practice suturing increases medical student comfort with suturing during clerkships: Suturing during cadaver dissection. Anat Sci Educ. 2018 Mar 30. doi: 10.1002/ase.1785. [Epub ahead of print].

publications Tozour J, Delahaye F, Suzuki M, Praiss A, Zhao Y, Cui L, Heo HJ, Greally J, Hughes F. Intrauterine hyperglycemia is associated with an impaired postnatal response to oxidative damage. Stem Cells Dev. 2018 Mar 29. doi: 10.1089/scd.2017.0232. [Epub ahead of print].

publications Jain S, Stock A, Macian F, Putterman C. A Distinct T Follicular Helper Cell Subset Infiltrates the Brain in Murine Neuropsychiatric Lupus. Front Immunol. 2018 Mar 13; 9:487.

publications Zheng Z, Wang ZG, Chen Y, Chen J, Khor S, Li J, He Z, Wang Q, Zhang H, Xu K, Fanghua G, Xiao J, Wang X. Spermidine promotes nucleus pulposus autophagy as a protective mechanism against apoptosis and ameliorates disc degeneration. J Cell Mol Med. 2018 Mar 25. doi: 10.1111/jcmm.13586. [Epub ahead of print].

publications Lázaro-Peña MI, Díaz-Balzac CA, Bülow HE, Emmons SW. Synaptogenesis Is Modulated by Heparan Sulfate in Caenorhabditis elegans. Genetics. 2018 Mar 20. pii: genetics.300837.2018. doi: 10.1534/genetics.118.300837. [Epub ahead of print].

publications  Kratschmer C, Levy M. Targeted Delivery of Auristatin-Modified Toxins to Pancreatic Cancer Using Aptamers. Mol Ther Nucleic Acids. 2018 Mar 2; 10:227-236.

publications Zamurrad S, Hatch HAM, Drelon C, Belalcazar HM, Secombe J. A Drosophila Model of Intellectual Disability Caused by Mutations in the Histone Demethylase KDM5. Cell Rep. 2018 Feb 27; 22(9):2359-2369.

publications Li L, Han L, Sun F, Zhou J, Ohaegbulam KC, Tang X, Zang X, Steinbrecher KA, Qu Z, Xiao G. NF-κB RelA renders tumor-associated macrophages resistant to and capable of directly suppressing CD8(+) T cells for tumor promotion. Oncoimmunology. 2018 Feb 27; 7(6):e1435250.

publications Racine JJ, Stewart I, Ratiu J, Christianson G, Lowell E, Helm K, Allocco J, Maser RS, Chen YG, Lutz CM, Roopenian D, Schloss J, DiLorenzo TP, Serreze DV. Improved Murine-MHC-Deficient HLA-Transgenic NOD-Mouse Models for Type 1 Diabetes Therapy Development. Diabetes. 2018 May; 67(5):923-935.

publications Pinho S, Marchand T, Yang E, Wei Q, Nerlov C, Frenette PS. Lineage-Biased Hematopoietic Stem Cells Are Regulated by Distinct Niches. Dev Cell. 2018 Mar 12; 44(5):634-641.

publications Burn C, Ramsey N, Garforth SJ, Almo S, Jacobs WR Jr, Herold BC. An HSV-2 single-cycle candidate vaccine deleted in glycoprotein D, ΔgD-2, protects male mice from lethal skin challenge with clinical isolates of HSV-1 and HSV-2. J Infect Dis. 2018 Feb 14; 217(5):754-758.

publications Sorrells S, Nik S, Casey M, Cameron RC, Truong H, Toruno C, Gulfo M, Lowe A, Jette C, Stewart RA, Bowman TV. Spliceosomal components protect embryonic neurons from R-loop-mediated DNA damage and apoptosis. Dis Model Mech. 2018 Jan 29. pii: dmm.031583. doi: 10.1242/dmm.031583. [Epub ahead of print].

publications Jiang JM, Seng EK, Zimmerman ME, Kim M, Lipton RB. Positively worded subscale score of the Perceived Stress Scale is associated with cognitive domain function. J Behav Brain Sci. 2017 Jul; 7(7):311-324.

publications Hayama R, Sparks S, Hecht LM, Dutta K, Cabana CM, Karp JM, Rout MP, Cowburn D. Thermodynamic characterization of the multivalent interactions underlying rapid and selective translocation through the nuclear pore complex. J Biol Chem. 2018 Jan 26. pii: jbc.AC117.001649. doi: 10.1074/jbc.AC117.001649. [Epub ahead of print].

publications Chalmers SA, Wen J, Doerner J, Stock A, Cuda CM, Makinde HM, Perlman H, Bosanac T, Webb D, Nabozny G, Fine JS, Klein E, Ramanujam M, Putterman C. Highly selective inhibition of Bruton's tyrosine kinase attenuates skin and brain disease in murine lupus. Arthritis Res Ther. 2018 Jan 25; 20(1):10.

publications Hodge DQ, Cui J, Gamble MJ, Guo W. Histone Variant MacroH2A1 Plays an Isoform-Specific Role in Suppressing Epithelial-Mesenchymal Transition. Sci Rep. 2018 Jan 16; 8(1):841.

publications Yakubu RR, Weiss LM, Silmon de Monerri NC. Posttranslational Modifications as Key Regulators of Apicomplexan Biology: Insights from Proteome-wide Studies. Mol Microbiol. 2018 Jan; 107(1):1-23.

publications Tutucci E, Vera M, Biswas J, Garcia J, Parker R, Singer RH. An improved MS2 system for accurate reporting of the mRNA life cycle. Nat Methods. 2018 Jan; 15(1):81-89.

publications Tu V, Yakubu R, Weiss LM. Observations on bradyzoite biology. Microbes Infect. 2017 Dec 26. pii: S1286-4579(17)30225-3. doi: 10.1016/j.micinf.2017.12.003. [Epub ahead of print].

publications Kratschmer C, Levy M. Effect of Chemical Modifications on Aptamer Stability in Serum. Nucleic Acid Ther. 2017 Dec; 27(6):335-344.

publications Warren C, Matsui T, Karp JM, Onikubo T, Cahill S, Brenowitz M, Cowburn D, Girvin M, Shechter D. Dynamic intramolecular regulation of the histone chaperone nucleoplasmin controls histone binding and release. Nat Commun. 2017 Dec 20; 8(1):2215.

publications Donnelly SK, Cabrera R, Mao SPH, Christin JR, Wu B, Guo W, Bravo-Cordero JJ, Condeelis JS, Segall JE, Hodgson L. Rac3 regulates breast cancer invasion and metastasis by controlling adhesion and matrix degradation. J Cell Biol. 2017 Dec 4; 216(12):4331-4349.

publications Aneke-Nash CS, Xue X, Qi Q, Biggs ML, Cappola A, Kuller L, Pollak M, Psaty BM, Siscovick D, Mukamal K, Strickler HD, Kaplan RC. The Association between IGF-I and IGFBP-3 and Incident Diabetes in an Older Population of Men and Women in the Cardiovascular Health Study. J Clin Endocrinol Metab. 2017 Dec 1; 102(12):4541-4547.

publications Nik S, Weinreb JT, Bowman TV. Developmental HSC Microenvironments: Lessons from Zebrafish. Adv Exp Med Biol. 2017; 1041:33-53.

publications Erami Z, Khalil BD, Salloum G, Yao Y, LoPiccolo J, Shymanets A, Nürnberg B, Bresnick AR, Backer JM. -----Rac1-Stimulated Macropinocytosis Enhances Gβϒ Activation of PI3Kβ. Biochem J. 2017 Nov 16; 474(23):3903-3914.

publications Pyronneau A, He Q, Hwang JY, Porch M, Contractor A, Zukin RS. Aberrant Rac1-cofilin signaling mediates defects in dendritic spines, synaptic function, and sensory perception in fragile X syndrome. Sci Signal. 2017 Nov 7; 10(504). pii: eaan0852. doi: 10.1126/scisignal.aan0852.

publications Byrd EA, Kielian M. An Alphavirus E2 Membrane-Proximal Domain Promotes Envelope Protein Lateral Interactions and Virus Budding. MBio. 2017 Nov 7; 8(6). pii: e01564-17. doi: 10.1128/mBio.01564-17.

publications Zahalka AH, Arnal-Estapé A, Maryanovich M, Nakahara F, Cruz CD, Finley LWS, Frenette PS. Adrenergic nerves activate an angio-metabolic switch in prostate cancer. Science. 2017 Oct 20; 358(6361):321-326.

publications Veenstra M, León-Rivera R, Li M, Gama L, Clements JE, Berman JW. Mechanisms of CNS Viral Seeding by HIV(+) CD14(+) CD16(+) Monocytes: Establishment and Reseeding of Viral Reservoirs Contributing to HIV-Associated Neurocognitive Disorders. MBio. 2017 Oct 24; 8(5). pii: e01280-17. doi: 10.1128/mBio.01280-17.

publications Firestone RS, Schramm VL. The Transition-State Structure for Human MAT2A from Isotope Effects. J Am Chem Soc. 2017 Oct 4; 139(39):13754-13760.

publications Osterbur Badhey ML, Bertalovitz AC, McDonald TV. Express with caution: Epitope tags and cDNA variants effects on hERG channel trafficking, half-life and function. J Cardiovasc Electrophysiol. 2017 Sep; 28(9):1070-1082.

publications Ren T, Piperdi S, Koirala P, Park A, Zhang W, Ivenitsky D, Zhang Y, Villanueva-Siles E, Hawkins DS, Roth M, Gorlick R. CD49b inhibits osteogenic differentiation and plays an important role in osteosarcoma progression. Oncotarget. 2017 Sep 23;8(50):87848-87859.

publications Ohaegbulam KC, Liu W, Jeon H, Almo SC, Zang X. Tumor-expressed immune checkpoint B7x promotes cancer progression and antigen-specific CD8 T cell exhaustion and suppressive innate immune cells. Oncotarget. 2017 Sep 20; 8(47):82740-82753.

publications Chen J, Wang Z, Mao Y, Zheng Z, Chen Y, Khor S, Shi K, He Z, Li J, Gong F, Liu Y, Hu A, Xiao J, Wang X. Liraglutide activates autophagy via GLP-1R to improve functional recovery after spinal cord injury. Oncotarget. 2017 Sep 8; 8(49):85949-85968.

publications Tewari A, Fremont R, Khodakhah K. It's not just the basal ganglia: Cerebellum as a target for dystonia therapeutics. Mov Disord. 2017 Aug 26. doi: 10.1002/mds.27123. [Epub ahead of print].

publications Saied-Santiago K, Townley RA, Attonito JD, da Cunha DS, Diaz-Balzac CA, Tecle E, Bülow HE. Coordination of Heparan Sulfate Proteoglycans with Wnt Signaling To Control Cellular Migrations and Positioning in Caenorhabditis elegans. Genetics. 2017 Aug; 206(4):1951-1967.

publications Bowen A, Wear M, Casadevall A. Antibody-mediated Catalysis in Infection and Immunity. Infect Immun. 2017 Aug 18; 85(9). pii: e00202-17.

publications Weiss CN, Ito K. A Macro View of MicroRNAs: The Discovery of MicroRNAs and Their Role in Hematopoiesis and Hematologic Disease. Int Rev Cell Mol Biol. 2017; 334:99-175.

publications Yang H, Sternson SM. Raphe Circuits on the Menu. Cell. 2017 Jul 27;170(3):409-410.

publications Glass LN, Swapna G, Chavadi SS, Tufariello JM, Mi K, Drumm JE, Lam TT, Zhu G, Zhan C, Vilchéze C, Arcos J, Chen Y, Bi L, Mehta S, Porcelli SA, Almo SC, Yeh SR, Jacobs WR Jr, Torrelles JB, Chan J. Mycobacterium tuberculosis universal stress protein Rv2623 interacts with the putative ATP binding cassette (APC) transporter Rv1747 to regulate mycobacterial growth. PLoS Pathog. 2017 Jul 28; 13(7):e1006515.

publications Jiang JM, Seng EK, Zimmerman ME, Kim M, Lipton RB. Positively worded subscale score of the Perceived Stress Scale is associated with cognitive domain function. J Behav Brain Sci. 2017 Jul; 7(7):311-324.

publications Garner TP, Lopez A, Reyna DE, Spitz AZ, Gavathiotis E. Progress in targeting the BCL-2 family of proteins. Curr Opin Chem Biol. 2017 Jul 20; 39:133-142.

publications Santos-Ledo A, Garcia-Macia M, Campbell PD, Gronska M, Marlow FL. Kinesin-1 promotes chondrocyte maintenance during skeletal morphogenesis. PLoS Genet.2017 Jul 17; 13(7):e1006918.

publications Wilson TJ, Gray MJ, Van Klinken JW, Kaczmarczyk M, Foxe JJ. Macronutrient composition of a morning meal and the maintenance of attention throughout the morning. Nutr Neurosci. 2017 Jul 17:1-15.

publications Snow M, Coen-Cagli R, Schwartz O. Adaptation in the visual cortex: a case for probing neuronal populations with natural stimuli. F1000Res. 2017 Jul 27; 6:1246.

publications Yang M, Arai A, Udagawa N, Hiraga T, Lijuan Z, Ito S, Komori T, Moriishi T, Matsuo K, Shimoda K, Zahalka AH, Kobayashi Y, Takahashi N, Mizoguchi T. Osteogenic Factor Runx2 Marks a Subset of Leptin Receptor-Positive Cells that Sit Atop the Bone Marrow Stromal Cell Hierarchy. Sci Rep. 2017 Jul 10; 7(1):4928.

publications Jiang JM, Seng EK, Zimmerman ME, Sliwinski M, Kim M, Lipton RB. Evaluation of the Reliability, Validity, and Predictive Validity of the Subscales of the Perceived Stress Scale in Older Adults. J Alzheimers Dis. 2017; 59(3):987-996.

publications Stock AD, Gelb S, Pasternak O, Ben-Zvi A, Putterman C. The Blood Brain Barrier and Neuropsychiatric Lupus: New perspectives in light of advances in understanding the neuroimmune interface. Autoimmun Rev. 2017 Jun; 16(6):612-619.

publications Keller CJ, Davidesco I, Megevand P, Lado FA, Malach R, Mehta AD. Tuning face perception with electrical stimulation of the fusiform gyrus. Hum Brain Mapp. 2017 Jun; 38(6):2830-2842.

publications Leung E, Xue A, Wang Y, Rougerie P, Sharma VP, Eddy R, Cox D, Condeelis J. Blood vessel endothelium-directed tumor cell streaming in breast tumors requires the HGF/C-Met signaling pathway. Oncogene. 2017 May 11; 36(19):2680-2692.

publications Han B, Polonais V, Sugi T, Yakubu R, Takvorian PM, Cali A, Maier K, Long M, Levy M, Tanowitz HB, Pan G, Delbac F, Zhou Z, Weiss LM. The role of microsporidian polar tube protein 4 (PTP4) in host cell infection. PLoS Pathog. 2017 Apr 20; 13(4):e1006341.

publications Yakubu RR, Silmon de Monerri NC, Nieves E, Kim K, Weiss LM. Comparative Monomethylarginine Proteomics Suggests that PRMT1 is a Significant Contributor to Arginine Monomethylation in Toxoplasma gondii. Mol Cell Proteomics. 2017 Apr; 16(4):567-580.

publications Andreyeva EN, Bernardo TJ, Kolesnikova TD, Lu X, Yarinich LA, Bartholdy BA, Guo X, Posukh OV, Healton S, Willcockson MA, Pindyurin AV, Zhimulev IF, Skoultchi AI, Fyodorov DV. Regulatory functions and chromatin loading dynamics of linker histone H1 during endoreplication in Drosophila. Genes Dev. 2017 Mar 15; 31(6):603-616.

publications Kerantzas CA, Jacobs WR Jr. Origins of Combination Therapy for Tuberculosis: Lessons for Future Antimicrobial Development and Application. MBio. 2017 Mar 14; 8(2). pii: e01586-16.

publications Wheat JC, Steidl U. ETO2-GLIS2: A Chimeric Transcription Factor Drives Leukemogenesis through a Neomorphic Transcription Network. Cancer Cell. 2017 Mar 13; 31(3):307-308.

publications Stanley RF, Piszczatowski RT, Bartholdy B, Mitchell K, McKimpson WM, Narayanagari S, Walter D, Todorova TI, Hirsch C, Makishima H, Will B, McMahon C, Gritsman K, Maciejewski JP, Kitsis RN, Steidl U. A myeloid tumor suppressor role for NOL3. J Exp Med. 2017 Mar 6; 214(3):753-771.

publications Firestone RS, Cameron SA, Karp JM, Arcus VL, Schramm VL. Heat Capacity Changes for Transition-State Analogue Binding and Catalysis with Human 5'-Methylthioadenosine Phosphorylase. ACS Chem Biol. 2017 Feb 17; 12(2):464-473.

publications Fremont R, Tewari A, Angueyra C, Khodakhah K. A role for cerebellum in the hereditary dystonia DYT1. Elife. 2017 Feb 15; 6. pii: e22775.

publications Karp JM, Sparks S, Cowburn D. Effects of FGFR2 kinase activation loop dynamics on catalytic activity. PLoS Comput Biol. 2017 Feb 2; 13(2):e1005360.

publications Khor S, Cai D. Hypothalamic and inflammatory basis of hypertension. Clin Sci (Lond). 2017 Feb 1; 131(3):211-223.

publications Cheng H, Janakiram M, Borczuk A, Lin J, Qiu W, Liu H, Chinai J, Halmos B, Perez-Soler R, Zang X. HHLA2, a new immune checkpoint member of the B7 family, is widely expressed in human lung cancer and associated with EGFR mutational status. Clin Cancer Res. 2017 Feb 1;23(3):825-832.

publications Harony-Nicolas H, Kay M, Hoffmann JD, Klein ME, Bozdagi-Gunal O, Riad M, Daskalakis NP, Sonar S, Castillo PE, Hof PR, Shapiro ML, Baxter MG, Wagner S, Buxbaum JD. Oxytocin improves behavioral and electrophysiological deficits in a novel Shank3-deficient rat. Elife. 2017 Jan 31;6. pii: e18904. doi: 10.7554/eLife.18904.

publications Wijetunga NA, Johnston AD, Maekawa R, Delahaye F, Ulahannan N, Kim K, Greally JM. SMITE: an R/Bioconductor package that identifies network modules by integrating genomic and epigenomic information. BMC Bioinformatics. 2017 Jan 18; 18(1):41.

publications Bowen A, Wear MP, Cordero R, Oscarson S, Casadevall A. A monoclonal antibody to Cryptococcus neoformans glucuronoxylomannan manifests hydrolytic activity for both peptides and polysaccharides. J Biol Chem. 2017 Jan 13; 292(2):417-434.

publications Tomita T, Sugi T, Yakubu R, Tu V, Ma Y, Weiss LM. Making Home Sweet and Sturdy: Toxoplasma gondii ppGalNAc-Ts Glycosylate in Hierarchical Order and Confer Cyst Wall Rigidity. MBio. 2017 Jan 10;8(1). pii: e02048-16. doi: 10.1128/mBio.02048-16.

publications Kaplan RC, Strizich G, Aneke-Nash C, Dominguez-Islas C, Bůžková P, Strickler H, Rohan T, Pollak M, Kuller L, Kizer JR, Cappola A, Li CI, Psaty BM, Newman A. Insulinlike growth factor binding protein-1 and ghrelin predict health outcomes among older adults: CHS cohort. J Clin Endocrinol Metab. 2017 Jan 1; 102(1):267-278.

publications Pignatelli J, Bravo-Cordero JJ, Roh-Johnson M, Gandhi SJ, Wang Y, Chen X, Eddy RJ, Xue A, Singer RH, Hodgson L, Oktay MH, Condeelis JS. Macrophage-dependent tumor cell transendothelial migration is mediated by Notch1/Mena(INV)-initiated invadopodium formation. Sci Rep. 2016 Nov 30;6:37874.

publications Vera M, Biswas J, Senecal A, Singer RH, Park HY. Single-Cell and Single-Molecule Analysis of Gene Expression Regulation. Annu Rev Genet. 2016 Nov 23; 50:267-291.

publications Cao LL, Riascos-Bernal DF, Chinnasamy P, Dunaway CM, Hou R, Pujato MA, O'Rourke BP, Miskolci V, Guo L, Hodgson L, Fiser A, Sibinga NE. Control of mitochondrial function and cell growth by the atypical cadherin Fat1. Nature. 2016 Nov 24; 539(7630):575-578.

publicationsWeidmann MD, Surve CR, Eddy RJ, Chen X, Gertler FB, Sharma VP, Condeelis JS. Mena(INV) dysregulates cortactin phosphorylation to promote invadopodium maturation. Sci Rep. 2016 Nov 8; 6:36142.

publications Mayer O, Jain P, Weisbrod T, Biro D, Ho L, Jacobs-Sera D, Hatfull GF, Jacobs WR Jr. Fluorescent reporter DS6A mycobacteriophages reveal unique variations in infectability and phage production in mycobacteria. J Bacteriol. 2016 Nov 4; 198(23):3220-3232.

publications Younts TJ, Monday HR, Dudok B, Klein ME, Jordan BA, Katona I, Castillo PE. Presynaptic Protein Synthesis Is Required for Long-Term Plasticity of GABA Release. Neuron. 2016 Oct 19; 92(2):479-492.

publications Heo HJ, Tozour JN, Delahaye F, Zhao Y, Cui L, Barzilai N, Einstein FH. Advanced aging phenotype is revealed by epigenetic modifications in rat liver after in utero malnutrition. Aging Cell. 2016 Oct; 15(5):964-72.

publicationsWijetunga NA, Pascual M, Tozour J, Delahaye F, Alani M, Adeyeye M, Wolkoff AW, Verma A, Greally JM. A pre-neoplastic epigenetic field defect in HCV-infected liver at transcription factor binding sites and polycomb targets. Oncogene. 2016 Oct 10. doi: 10.1038/onc.2016.340.

publicationsAguilar JL, Varshney AK, Pechuan X, Dutta K, Nosanchuk JD, Fries BC. Monoclonal antibodies protect from Staphylococcal Enterotoxin K (SEK) induced toxic shock and sepsis by USA300 Staphylococcus aureus. Virulence. 2016 Oct 7:0.

publicationsSnow M, Coen-Cagli R, Schwartz O. Specificity and timescales of cortical adaptation as inferences about natural movie statistics. J Vis. 2016 Oct 1;16(13). doi: 10.1167/16.13.1.

publications Mani KM, Savage T, Basu I, Scandiuzzi L, Asp P, Guha C. Epigenetic Priming and High-Dose Radiation for Enhanced Immune Response in Pancreatic Cancer. Int J Radiat Oncol Biol Phys. 2016 Oct 1; 96(2S):S86-S87.

publications Shakkottai VG, Batla A, Bhatia K, Dauer WT, Dresel C, Niethammer M, Eidelberg D, Raike RS, Smith Y, Jinnah HA, Hess EJ, Meunier S, Hallett M, Fremont R, Khodakhah K, LeDoux MS, Popa T, Gallea C, Lehericy S, Bostan AC, Strick PL. Current Opinions and Areas of Consensus on the Role of the Cerebellum in Dystonia. Cerebellum. 2016 Oct 12. Review.

publications Sawicka K*, Pyronneau A*, Chao M, Bennett MV, Zukin RS. Elevated ERK/p90 ribosomal S6 kinase activity underlies audiogenic seizure susceptibility in fragile X mice. Proc Natl Acad Sci U S A. 2016 Sep 23. pii: 201610812. [Epub ahead of print]. *Contributed equally.

publicationsBowen A, Casadevall A. Revisiting the immunoglobulin intramolecular signaling hypothesis. Trends Immunol.2016 Nov; 37(11):721-723.

publications Wen J, Stock AD, Chalmers SA, Putterman C. The role of B cells and autoantibodies in neuropsychiatric lupus. Autoimmun Rev. 2016 Sep; 15(9):890-5.

publicationsWijetunga NA, Belbin TJ, Burk RD, Whitney K, Abadi M, Greally JM, Einstein MH, Schlecht NF. Novel epigenetic changes in CDKN2A are associated with progression of cervical intraepithelial neoplasia. Gynecol Oncol. 2016 Sep; 142(3):566-73.

publicationsWijetunga NA, Ben-Dayan M, Tozour J, Burk RD, Schlecht NF, Einstein MH, Greally JM. A polycomb-mediated epigenetic field defect precedes invasive cervical carcinoma. Oncotarget. 2016 Sep 20; 7(38):62133-62143.

publicationsDíaz-Balzac CA, Rahman M, Lázaro-Peña MI, Martin Hernandez LA, Salzberg Y, Aguirre-Chen C, Kaprielian Z, Bülow HE. Muscle- and skin-derived cues jointly orchestrate patterning of somatosensory dendrites. Curr Biol. 2016 Sep 12; 26(17):2379-87

publications Kravchick DO, Karpova A, Hrdinka M, Lopez-Rojas J, Iacobas S, Carbonell AU, Iacobas DA, Kreutz MR, Jordan BA. Synaptonuclear messenger PRR7 inhibits c-Jun ubiquitination and regulates NMDA-mediated excitotoxicity. EMBO J. 2016 Sep 1; 35(17):1923-34.

publications Sato H, Wheat JC, Steidl U, Ito K. DNMT3A and TET2 in the pre-leukemic phase of hematopoietic disorders. Front Oncol. 2016 Aug 22; 6:187.

publicationsKoirala P, Roth ME, Gill J, Chinai JM, Ewart MR, Piperdi S, Geller DS, Hoang BH, Fatakhova YV, Ghorpade M, Zang X, Gorlick R. HHLA2, a member of the B7 family, is expressed in human osteosarcoma and is associated with metastases and worse survival. Sci Rep. 2016 Aug 17;6:31154.

publications Riascos-Bernal DF, Chinnasamy P, Cao LL, Dunaway CM, Valenta T, Basler K, Sibinga NE. β-Catenin C-terminal signals suppress p53 and are essential for artery formation. Nat Commun. 2016 Aug 8; 7:12389.

publications Eslami V, Katz MJ, White RS, Sundermann E, Jiang JM, Ezzati A, Lipton RB. Pain intensity and pain interference in older adults: Role of gender, obesity and high-sensitivity C-reactive protein. Gerontology. 2017; 63(1):3-12.

publications Geller DS, Morris J, Revskaya E, Kahn M, Zhang W, Piperdi S, Park A, Koirala P, Guzik H, Hall C, Hoang B, Yang R, Roth M, Gill J, Gorlick R, Dadachova E. Targeted therapy of osteosarcoma with radiolabeled monoclonal antibody to an insulin-like growth factor-2 receptor (IGF2R). Nucl Med Biol. 2016 Jul 30; 43(12):812-817.

publicationsKoirala P, Roth ME, Gill J, Piperdi S, Chinai JM, Geller DS, Hoang BH, Park A, Fremed MA, Zang X, Gorlick R. Immune infiltration and PD-L1 expression in the tumor microenvironment are prognostic in osteosarcoma. Sci Rep. 2016 Jul 26; 6:30093.

publicationsPiszczatowski RT, Lents NH. Regulation of the CCN genes by vitamin D: A possible adjuvant therapy in the treatment of cancer and fibrosis. Cell Signal. 2016 Jul 25; 28(10):1604-1613.

publications Picarda E, Ohaegbulam KC, Zang X. Molecular Pathways: Targeting B7-H3 (CD276) for Human Cancer Immunotherapy. Clin Cancer Res. 2016 Jul 15; 22(14):3425-31.

publications Choi CH, Schoenfeld BP, Bell AJ, Hinchey J, Rosenfelt C, Gertner MJ, Campbell SR, Emerson D, Hinchey P, Kollaros M, Ferrick NJ, Chambers DB, Langer S, Sust S, Malik A, Terlizzi AM, Liebelt DA, Ferreiro D, Sharma A, Koenigsberg E, Choi RJ, Louneva N, Arnold SE, Featherstone RE, Siegel SJ, Zukin RS, McDonald TV, Bolduc FV, Jongens TA, McBride SM. Multiple drug treatments That increase cAMP signaling restore long-term memory and aberrant signaling in Fragile X Syndrome models. Front Behav Neurosci. 2016 Jun 30; 10:136.

publicationsChiang SP, Cabrera RM, Segall JE. Tumor cell intravasation. A review in the theme: Cell and molecular processes in cancer metastasis. Am J Physiol Cell Physiol. 2016 Jul 1; 311(1):C1-C14.

publicationsArora A, Deniskin R, Sosa Y, Nishtala SN, Henrich PP, Kumar TR, Fidock DA, Akabas MH. Substrate and inhibitor specificity of the Plasmodium berghei Equilibrative Nucleoside Transporter Type 1 (PbENT1). Mol Pharmacol. 2016 Jun; 89(6):678-85.

publicationsTow A, Holtzer R, Wang C, Sharan A, Kim SJ, Gladstein A, Blum Y, Verghese J. Cognitive Reserve and Postoperative Delirium in Older Adults. J Am Geriatr Soc. 2016 Jun; 64(6):1341-6.

publicationsKaufman OH, Marlow FL. Methods to study maternal regulation of germ cell specification in zebrafish. Methods Cell Biol. 2016; 134:1-32.

publications Wen J, Chen C, Stock A, Doerner J, Gulinello M, Putterman C. Intracerebroventricular administration of TNF-like weak inducer of apoptosis induces depression-like behavior and cognitive dysfunction in non-autoimmune mice. Brain Behav Immun. 2016 May; 54:27-37.

publications Raveh B*, Karp JM*, Sparks S*, Dutta K, Rout MP, Sali A, Cowburn D. Slide-and-exchange mechanism for rapid and selective transport through the nuclear pore complex. Proc Natl Acad Sci U S A. 2016 May 3; 113(18):E2489-97. *contributed equally

publications Maier KE, Jangra RK, Shieh KR, Cureton DK, Xiao H, Snapp EL, Whelan SP, Chandran K, Levy M. A New Transferrin Receptor Aptamer Inhibits New World Hemorrhagic Fever Mammarenavirus Entry. Mol Ther Nucleic Acids. 2016 May 24; 5:e321.

publications Picarda E, Ohaegbulam KC, Zang X. Molecular Pathways: Targeting B7-H3 (CD276) for Human Cancer Immunotherapy. Clin Cancer Res. 2016 Jul 15; 22(14):3425-31.

publicationsKeller CJ, Chen C, Lado FA, Khodakhah K. The Limited Utility of Multiunit Data in Differentiating Neuronal Population Activity. PLoS One. 2016 Apr 25; 11(4):e0153154.

publications Wen J, Doerner J, Chalmers S, Stock A, Wang H, Gullinello M, Shlomchik MJ, Putterman C. B cell and/or autoantibody deficiency do not prevent neuropsychiatric disease in murine systemic lupus erythematosus. J Neuroinflammation. 2016 Apr 7; 13(1):73.

publicationsStanley RF, Steidl U. Molecular Mechanism of Mutant CALR-Mediated Transformation. Cancer Discov. 2016 Apr; 6(4):344-6.

publicationsDeniskin R, Frame IJ, Sosa Y, Akabas MH. Targeting the Plasmodium vivax equilibrative nucleoside transporter 1 (PvENT1) for antimalarial drug development. Int J Parasitol Drugs Drug Resist. 2016; 6(1):1-11.

publications Ndungo E, Herbert AS, Raaben M, Obernosterer G, Biswas R, Miller EH, Wirchnianski AS, Carette JE, Brummelkamp TR, Whelan SP, Dye JM, Chandran K. A Single Residue in Ebola Virus Receptor NPC1 Influences Cellular Host Range in Reptiles. mSphere. 2016 Mar 30; 1(2). pii: e00007-16.

publicationsStanley RF, Steidl U. Ectopic DNMT3B expression delays leukemogenesis. Blood. 2016 Mar 24; 127(12):1525-6.

publicationsDíaz-Balzac CA, Lázaro-Peña MI, Vázquez-Figueroa LD, Díaz-Balzac RJ, García-Arrarás JE. Holothurian Nervous System Diversity Revealed by Neuroanatomical Analysis. PLoS One. 2016 Mar 17; 11(3):e0151129.

publications Sidney J, Schloss J, Moore C, Lindvall M, Wriston A, Hunt DF, Shabanowitz J, DiLorenzo TP, Sette A. Characterization of the peptide binding specificity of the HLA class I alleles B*38:01 and B*39:06. Immunogenetics. 2016 Mar; 68(3):231-6.

publicationsShemesh A, Taub CC. Inferolateral ST elevation in Boerhaave syndrome. Am J Med. 2016 Mar; 129(3):e27-8.

publications Fang FC, Bowen A, Casadevall A. NIH peer review percentile scores are poorly predictive of grant productivity. Elife. 2016 Feb 16; 5. pii: e13323. doi: 10.7554/eLife.13323.

publicationsJanda A, Bowen A, Greenspan NS, Casadevall A. Ig constant region effects on variable region structure and function. Front Microbiol. 2016 Feb 4; 7:22.

publicationsKlein ME, Monday H, Jordan BA. Proteostasis and RNA binding proteins in synaptic plasticity and in the pathogenesis of neuropsychiatric disorders. Neural Plast. 2016; 2016:3857934.

publications Babad J, Ali R, Schloss J, DiLorenzo TP. An HLA-transgenic mouse model of Type 1 diabetes that incorporates the reduced but not abolished thymic insulin expression seen in patients. J Diabetes Res.2016; 2016:7959060. doi: 10.1155/2016/7959060.

publications Xie Q, McGreal R, Harris R, Gao CY, Liu W, Reneker LW, Musil LS, Cvekl A. Regulation of c-Maf and αA-crystallin in ocular lens by FGF signaling. J Biol Chem. 2016 Feb 19; 291(8):3947-58.

publicationsAneke-Nash CS, Dominguez-Islas C, Bůžková P, Qi Q, Xue X, Pollak M, Strickler HD, Kaplan RC. Agreement between circulating IGF-I, IGFBP-1 and IGFBP-3 levels measured by current assays versus unavailable assays previously used in epidemiological studies. Growth Horm IGF Res. 2016 Feb; 26:11-6.

publications Tufariello JM, Chapman JR, Kerantzas CA, Wong KW, Vilchèze C, Jones CM, Cole LE, Tinaztepe E, Thompson V, Fenyö D, Niederweis M, Ueberheide B, Philips JA, Jacobs WR Jr. Separable roles for Mycobacterium tuberculosis ESX-3 effectors in iron acquisition and virulence. Proc Natl Acad Sci U S A. 2016 Jan 19; 113(3):E348-57.

publicationsUchime O, Dai Z, Biris N, Lee D, Sidhu SS, Li S, Lai JR, Gavathiotis E. Synthetic Antibodies Inhibit Bcl-2-associated X Protein (BAX) through Blockade of the N-terminal Activation Site. J Biol Chem. 2016 Jan 1; 291(1):89-102.

publications Martinez-Lopez N, Garcia-Macia M, Sahu S, Athonvarangkul D, Liebling E, Merlo P, Cecconi F, Schwartz GJ, Singh R. Autophagy in the CNS and Periphery Coordinate Lipophagy and Lipolysis in the Brown Adipose Tissue and Liver. Cell Metab. 2016 Jan 12; 23(1):113-27.

publications Ng M, Ndungo E, Kaczmarek ME, Herbert AS, Binger T, Kuehne AI, Jangra RK, Hawkins JA, Gifford RJ, Biswas R, Demogines A, James RM, Yu M, Brummelkamp TR, Drosten C, Wang LF, Kuhn JH, Müller MA, Dye JM, Sawyer SL, Chandran K. Filovirus receptor NPC1 contributes to species-specific patterns of ebolavirus susceptibility in bats. Elife.2015 Dec 23; 4. pii: e11785. doi: 10.7554/eLife.11785.

publicationsLoPiccolo J, Kim SJ, Shi Y, Wu B, Wu H, Chait BT, Singer RH, Sali A, Brenowitz M, Bresnick AR, Backer JM. Assembly and Molecular Architecture of the Phosphoinositide 3-Kinase p85α Homodimer. J Biol Chem. 2015 Dec 18; 290(51):30390-405.

publications Nadel J, Athanasiadou R, Lemetre C, Wijetunga NA, Ó Broin P, Sato H, Zhang Z, Jeddeloh J, Montagna C, Golden A, Seoighe C, Greally JM. RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships. Epigenetics Chromatin.2015 Nov 16; 8:46.

publications Tufariello JM, Kerantzas CA, Vilchèze C, Calder RB, Nordberg EK, Fischer JA, Hartman TE, Yang E, Driscoll T, Cole LE, Sebra R, Maqbool SB, Wattam AR, Jacobs WR Jr. The Complete Genome Sequence of the Emerging Pathogen Mycobacterium haemophilum Explains Its Unique Culture Requirements. MBio. 2015 Nov 17; 6(6). pii: e01313-15.

publications Silmon de Monerri NC, Yakubu RR, Chen AL, Bradley PJ, Nieves E, Weiss LM, Kim K. The Ubiquitin Proteome of Toxoplasma gondii Reveals Roles for Protein Ubiquitination in Cell-Cycle Transitions. Cell Host Microbe. 2015 Nov 11; 18(5):621-33.

publicationsBowen A, Casadevall A. Reply to Fiscella: The phases of biomedical research should be studied to optimize health outcomes. Proc Natl Acad Sci U S A. 2015 Nov 24; 112(47):E6413.

publicationsStock AD, Wen J, Doerner J, Herlitz LC, Gulinello M, Putterman C. Neuropsychiatric systemic lupus erythematosus persists despite attenuation of systemic disease in MRL/lpr mice. J Neuroinflammation. 2015 Nov 6; 12(1):205.

publicationsOkoye-Okafor UC, Bartholdy B, Cartier J, Gao EN, Pietrak B, Rendina AR, Rominger C, Quinn C, Smallwood A, Wiggall KJ, Reif AJ, Schmidt SJ, Qi H, Zhao H, Joberty G, Faelth-Savitski M, Bantscheff M, Drewes G, Duraiswami C, Brady P, Groy A, Narayanagari SR, Antony-Debre I, Mitchell K, Wang HR, Kao YR, Christopeit M, Carvajal L, Barreyro L, Paietta E, Makishima H, Will B, Concha N, Adams ND, Schwartz B, McCabe MT, Maciejewski J, Verma A, Steidl U. New IDH1 mutant inhibitors for treatment of acute myeloid leukemia. Nat Chem Biol. 2015 Nov; 11(11):878-86.

publicationsCampbell PD, Heim AE, Smith MZ, Marlow FL. Kinesin-1 interacts with Bucky ball to form germ cells and is required to pattern the zebrafish body axis. Development. 2015 Sep 1; 142(17):2996-3008.

publicationsBowen A, Casadevall A. Increasing disparities between resource inputs and outcomes, as measured by certain health deliverables, in biomedical research. Proc Natl Acad Sci U S A. 2015 Sep 8; 112(36):11335-40.

publications Nabet B, Ó Broin P, Reyes JM, Shieh K, Lin CY, Will CM, Popovic R, Ezponda T, Bradner JE, Golden AA, Licht JD. Deregulation of the Ras-Erk Signaling Axis Modulates the Enhancer Landscape. Cell Rep. 2015 Aug 25; 12(8):1300-1313.

publications Rhee DB, Croken MM, Shieh KR, Sullivan J, Micklem G, Kim K, Golden A. toxoMine: an integrated omics data warehouse for Toxoplasma gondii systems biology research. Database (Oxford). 2015 Jun 30; pii: bav066. doi: 10.1093/database/bav066.

publicationsFremont R, Tewari A, Khodakhah K. Aberrant Purkinje cell activity is the cause of dystonia in a shRNA-based mouse model of Rapid Onset Dystonia-Parkinsonism. Neurobiol Dis. 2015 Jun 17; 82:200-212.

publicationsSmith C, Pechuan X, Puzio RS, Biro D, Bergman A. Potential unsatisfiability of cyclic constraints on stochastic biological networks biases selection towards hierarchical architectures. J R Soc Interface. 2015 Jul 6;12(108). pii: 20150179. doi: 10.1098/rsif.2015.0179.

publicationsTindi JO, Chávez AE, Cvejic S, Calvo-Ochoa E, Castillo PE, Jordan BA. ANKS1B Gene Product AIDA-1 Controls Hippocampal Synaptic Transmission by Regulating GluN2B Subunit Localization. J Neurosci. 2015 Jun 17; 35(24):8986-96.

publicationsDíaz-Balzac CA, Lázaro-Peña MI, Ramos-Ortiz GA, Bülow HE. The Adhesion Molecule KAL-1/anosmin-1 Regulates Neurite Branching through a SAX-7/L1CAM-EGL-15/FGFR Receptor Complex. Cell Rep. 2015 Jun 9; 11(9):1377-84.

publications Wen J, Doerner J, Weidenheim K, Xia Y, Stock A, Michaelson JS, Baruch K, Deczkowska A, Gulinello M, Schwartz M, Burkly LC, Putterman C. TNF-like weak inducer of apoptosis promotes blood brain barrier disruption and increases neuronal cell death in MRL/lpr mice. J Autoimmun. 2015 Jun; 60:40-50.

publicationsAneke-Nash CS, Parrinello CM, Rajpathak SN, Rohan TE, Strotmeyer ES, Kritchevsky SB, Psaty BM, Bůžková P, Kizer JR, Newman AB, Strickler HD, Kaplan RC. Changes in insulin-like growth factor-I and its binding proteins are associated with diabetes mellitus in older adults. J Am Geriatr Soc. 2015 May; 63(5):902-9.

publicationsNicholas MP, Berger F, Rao L, Brenner S, Cho C, Gennerich A. Cytoplasmic dynein regulates its attachment to microtubules via nucleotide state-switched mechanosensing at multiple AAA domains. Proc Natl Acad Sci U S A. 2015 May 19; 112(20):6371-6.

publications Janakiram M, Chinai J, Fineberg S, Fiser A, Montagna C, Medaverepu R, Castano E, Jeon H, Ohaegbulam KC, Zhao R, Zhao A, Almo S, Sparano JA, Zang X. Expression, clinical significance, and receptor identification of the newest B7 family member HHLA2 protein. Clin Cancer Res. 2015 May 15; 21(10):2359-66.

publicationsJanda A, Eryilmaz E, Nakouzi A, Pohl MA, Bowen A, Casadevall A. Variable region identical IgA and IgE to Cryptococcus neoformans capsular polysaccharide manifest specificity differences. J Biol Chem. 2015 May 8; 290(19):12090-100.

publications Xiong XD, Jung HJ, Gombar S, Park JY, Zhang CL, Zheng H, Ruan J, Li JB, Kaeberlein M, Kennedy BK, Zhou Z, Liu X, Suh Y. MicroRNA transcriptome analysis identifies miR-365 as a novel negative regulator of cell proliferation in Zmpste24-deficient mouse embryonic fibroblasts. Mutat Res. 2015 Apr 24; 777:69-78.

publications  Frame IJ*, Deniskin R*, Arora A, Akabas MH. Purine import into malaria parasites as a target for antimalarial drug development. Ann N Y Acad Sci. 2015 Apr; 1342:19-28. *Contributed equally.

publications Wu B, Miskolci V, Sato H, Tutucci E, Kenworthy CA, Donnelly SK, Yoon YJ, Cox D, Singer RH, Hodgson L. Synonymous modification results in high-fidelity gene expression of repetitive protein and nucleotide sequences. Genes Dev. 2015 Apr 15; 29(8):876-86.

publications Martinez-Lopez N, Athonvarangkul D, Singh R. Autophagy and aging. Adv Exp Med Biol. 2015; 847:73-87.

publicationsPark C, Suh Y, Cuervo AM. Regulated degradation of Chk1 by chaperone-mediated autophagy in response to DNA damage. Nat Commun. 2015 Apr 16; 6:6823.

publications Gray MJ, Frey HP, Wilson TJ, Foxe JJ. Oscillatory Recruitment of Bilateral Visual Cortex during Spatial Attention to Competing Rhythmic Inputs. J Neurosci. 2015 Apr 8; 35(14):5489-503.

publicationsSchneider JL, Villarroya J, Diaz-Carretero A, Patel B, Urbanska AM, Thi MM, Villarroya F, Santambrogio L, Cuervo AM. Loss of hepatic chaperone-mediated autophagy accelerates proteostasis failure in aging. Aging Cell. 2015 Apr; 14(2):249-64.

publications Mukherjee G, Chaparro RJ, Schloss J, Smith C, Bando CD, DiLorenzo TP. Glucagon-reactive Islet-infiltrating CD8 T Cells in NOD Mice. Immunology. 2015 Apr; 144(4):631-40.

publicationsCampbell PD, Chao JA, Singer RH, Marlow FL. Dynamic visualization of transcription and RNA subcellular localization in zebrafish. Development. 2015 Apr 1; 142(7):1368-74.

publicationsFrame IJ*, Deniskin R*, Rinderspacher A, Katz F, Deng SX, Moir RD, Adjalley SH, Coburn-Flynn O, Fidock DA, Willis IM, Landry DW, Akabas MH. Yeast-Based High-Throughput Screen Identifies Plasmodium falciparum Equilibrative Nucleoside Transporter 1 Inhibitors That Kill Malaria Parasites. ACS Chem Biol. 2015 Mar 20; 10(3):775-83. (*Contributed equally).

publicationsKlein ME, Castillo PE, Jordan BA. Coordination between Translation and Degradation Regulates Inducibility of mGluR-LTD. Cell Rep. 2015 Mar 3. pii: S2211-1247(15)00166-7.

publications Ramos MP, Wijetunga NA, McLellan AS, Suzuki M, Greally JM. DNA demethylation by 5-aza-2'-deoxycytidine is imprinted, targeted to euchromatin, and has limited transcriptional consequences. Epigenetics Chromatin. 2015 Mar 17; 8:11.

publications Salamon RS, Dbouk HA, Collado D, Lopiccolo J, Bresnick AR, Backer JM. Identification of the Rab5 Binding Site in p110β: Assays for PI3Kβ Binding to Rab5. Methods Mol Biol. 2015; 1298:271-81.

publicationsWeiss CN, Ito K. DNA Damage: A Sensible Mediator of the Differentiation Decision in Hematopoietic Stem Cells and in Leukemia. Int J Mol Sci. 2015 Mar 17; 16(3):6183-6201.

publicationsSanchez-Casalongue ME, Lee J, Diamond A, Shuldiner S, Moir RD, Willis IM. Differential Phosphorylation of a Regulatory Subunit of Protein Kinase CK2 by TOR Complex 1 Signaling and the Cdc-like Kinase Kns1. J Biol Chem. 2015 Mar 13; 290(11):7221-33.

publications Zoi I, Motley MW, Antoniou D, Schramm VL, Schwartz SD. Enzyme Homologues Have Distinct Reaction Paths through Their Transition States. J Phys Chem B. 2015 Mar 5; 119(9):3662-8.

publicationsNicholas MP, Höök P, Brenner S, Wynne CL, Vallee RB, Gennerich A. Control of cytoplasmic dynein force production and processivity by its C-terminal domain. Nat Commun. 2015 Feb 11;6:6206.

publicationsBerko ER, Greally JM. How might epigenetic dysregulation in early embryonic life contribute to autism spectrum disorder? Epigenomics. 2015 Feb; 7(1):1-4.

publications Valenzuela-Iglesias A, Sharma VP, Beaty BT, Ding Z, Gutierrez-Millan LE, Roy P, Condeelis JS, Bravo-Cordero JJ. Profilin1 regulates invadopodium maturation in human breast cancer cells. Eur J Cell Biol. 2015 Feb; 94(2):78-89.

publications  Karp JM, Erylimaz E, Cowburn D. Correlation of chemical shifts predicted by molecular dynamics simulations for partially disordered proteins. J Biomol NMR. 2015 Jan; 61(1):35-45.

publications Rosenblum JM, Wijetunga NA, Fazzari MJ, Krailo M, Barkauskas DA, Gorlick R, Greally JM. Predictive Properties of DNA Methylation Patterns in Primary Tumor Samples for Osteosarcoma Relapse Status. Epigenetics. 2015 Jan 2; 10(1):31-9.

publications Jeon H, Vigdorovich V, Garrett-Thomson SC, Janakiram M, Ramagopal UA, Abadi YM, Lee JS, Scandiuzzi L, Ohaegbulam KC, Chinai JM, Zhao R, Yao Y, Mao Y, Sparano JA, Almo SC, Zang X. Structure and cancer immunotherapy of the b7 family member b7x. Cell Rep.2014 Nov 6; 9(3):1089-98.

publications  Shemesh A, Wang Y, Yang Y, Yang GS, Johnson DE, Backer JM, Pessin JE, Zong H. Suppression of mTOR1 activation in acid- α -glucosidase deficient cells and mice is ameliorated by leucine supplementation. Am J Physiol Regul Integr Comp Physiol. 2014 Nov 15; 307(10):R1251-9.

publications  Campbell PD, Shen K, Sapio MR, Glenn TD, Talbot WS, Marlow FL. Unique Function of Kinesin Kif5A in Localization of Mitochondria in Axons. J Neurosci. 2014 Oct 29; 34(44):14717-32.

publications  Wijetunga NA, Delahaye F, Zhao YM, Golden A, Mar JC, Einstein FH, Greally JM. The meta-epigenomic structure of purified human stem cell populations is defined at cis-regulatory sequences. Nat Comm. 2014 Oct 20; 5:5195.

publications Delahaye F, Wijetunga NA, Heo HJ, Tozour JN, Zhao YM, Greally JM, Einstein FH. Sexual dimorphism in epigenomic responses of stem cells to extreme fetal growth. Nat Commun. 2014 Oct 10; 5:5187.

publications  Hartung O, Forbes MM, Marlow FL. Zebrafish vasa is required for germ-cell differentiation and maintenance. Mol Reprod Dev. 2014 Oct; 81(10):946-61.

publications  Keller CJ, Honey CJ, Mégevand P, Entz L, Ulbert I, Mehta AD. Mapping human brain networks with cortico-cortical evoked potentials. Philos Trans R Soc Lond B Biol Sci. 2014 Oct 5; 369(1653) pii: 20130528.

publications  Beaty BT, Condeelis J. Digging a little deeper: The stages of invadopodium formation and maturation. Eur J Cell Biol. 2014 Oct; 93(10-12):438-44.

publications  Schneider JL, Suh Y, Cuervo AM. Deficient Chaperone-Mediated Autophagy in Liver Leads to Metabolic Dysregulation. Cell Metab. 2014 Sep 2; 20(3):417-32.

publications  Shin DS, Jordan A, Basu S, Thomas RM, Bandyopadhyay S, de Zoeten EF, Wells AD, Macian F. Regulatory T cells suppress CD4+ T cells through NFAT-dependent transcriptional mechanisms. EMBO Rep. 2014 Sep;1 5(9):991-9.

publications  Manning EP, Laskowski LK, Nelson LS, Touger M. Young woman with epigastric pain and vomiting. Ann Emerg Med. 2014 Sep; 64(3):330-3.

publications Charles SH, Tow AC, Verghese J. Objective cardiac markers and cerebrovascular lesions in Indian seniors. J Epidemiol Glob Health. 2014 Sep; 4(3):245-7.

publications  Fremont R, Calderon DP, Maleki S, Khodakhah K. Abnormal high-frequency burst firing of cerebellar neurons in rapid-onset dystonia-parkinsonism. J Neurosci. 2014 Aug 27; 34(35):11723-32.

publications Díaz-Balzac CA, Lázaro-Peñao MI, Tecle E, Gomez N, Bülow HE. Complex Cooperative Functions of Heparan Sulfate Proteoglycans Shape Nervous System Development in Caenorhabditis elegans. G3 (Bethesda). 2014 Aug 5; 4(10):1859-70. 

publications van Oers JM, Edwards Y, Chahwan R, Zhang W, Smith C, Pechuan X, Schaetzlein S, Jin B, Wang Y, Bergman A, Scharff MD, Edelmann W. The MutSβ complex is a modulator of p53-driven tumorigenesis through its functions in both DNA double-strand break repair and mismatch repair. Oncogene. 2014 Jul 24; 33(30):3939-46.

publications Zhou ZN, Sharma VP, Beaty BT, Roh-Johnson M, Peterson EA, Van Rooijen N, Kenny PA, Wiley HS, Condeelis JS, Segall JE. Autocrine HBEGF expression promotes breast cancer intravasation, metastasis and macrophage-independent invasion in vivo. Oncogene. 2014 Jul 17; 33(29):3784-93.

publications Hazan RB, Kim S, Yao J, Suyama K, Qian X, Qian BZ, Bandyopadhyay S, Loudig OD, De Leon-Rodriguez C, Zhou ZN, Segall JE, Macian F, Norton L. Slug Promotes Survival during Metastasis through Suppression of Puma-mediated Apoptosis. Cancer Res. 2014 Jul 15; 74(14):3695-706.

publications Kwon M, Lee SJ, Wang Y, Rybak Y, Luna A, Reddy S, Adem A, Beaty BT, Condeelis JS, Libutti SK. Filamin A interacting protein 1-like inhibits WNT signaling and MMP expression to suppress cancer cell invasion and metastasis. Int J Cancer. 2014 Jul 1; 135(1):48-60.

publications  Wengerter BC, Katakowski JA, Rosenberg J, Park CG, Almo SC, Palliser D, Levy M. Aptamer-Targeted Antigen Delivery. Mol Ther. 2014 Jul; 22(7):1375-87.

publications Sussman ES, Chen S, Sussman-Fort J, Dinces E. The Five Myths of MMN: Redefining How to Use MMN in Basic and Clinical Research. Brain Topogr. 2014 Jul; 27(4):553-64.

publications  Keller CJ, Honey CJ, Entz L, Bickel S, Groppe DM, Toth E, Ulbert I, Lado FA, Mehta AD. Corticocortical evoked potentials reveal projectors and integrators in human brain networks. J Neurosci. 2014 Jul 2; 34(27):9152-63.

publications  Nakahara F, Weiss CN, Ito K. The role of PML in hematopoietic and leukemic stem cell maintenance.Int J Hematol. 2014 Jul; 100(1):18-26.  

publications O'Rourke BP, Gomez-Ferreria MA, Berk RH, Hackl AM, Nicholas MP, O'Rourke SC, Pelletier L, Sharp DJ. Cep192 Controls the Balance of Centrosome and Non-Centrosomal Microtubules during Interphase. PLoS One. 2014 Jun 27; 9(6):e101001.

publications Soudja SM, Chandrabos C, Yakob E, Veenstra M, Palliser D, Lauvau G. Memory-T-Cell-Derived Interferon-γ Instructs Potent Innate Cell Activation for Protective Immunity. Immunity. 2014 Jun 19; 40(6):974-988.

publications Moore RK, Abdullah S, Tardiff JC. Allosteric effects of cardiac troponin TNT1 mutations on actomyosin binding: A novel pathogenic mechanism for hypertrophic cardiomyopathy. Arch Biochem Biophys. 2014 Jun 15; 552-553:21-8.

publications Varshney AK, Wang X, Aguilar JL, Scharff MD, Fries BC. Isotype Switching Increases Efficacy of Antibody Protection against Staphylococcal Enterotoxin B-Induced Lethal Shock and Staphylococcus aureus Sepsis in Mice. MBio. 2014 Jun 10; 5(3). pii: e01007-14.

publications Beaty BT, Wang Y, Bravo-Cordero JJ, Sharma VP, Miskolci V, Hodgson L, Condeelis J. Talin regulates moesin-NHE-1 recruitment to invadopodia and promotes mammary tumor metastasis. J Cell Biol. 2014 Jun 9; 205(5):737-51.

publications Brojatsch J, Lima H, Kar AK, Jacobson LS, Muehlbauer SM, Chandran K, Diaz-Griffero F. A proteolytic cascade controls lysosome rupture and necrotic cell death mediated by lysosome-destabilizing adjuvants. PLoS One. 2014 Jun 3;9(6):e95032.

publications Ezzati A, Jiang J, Katz MJ, Sliwinski MJ, Zimmerman ME, Lipton RB. Validation of the Perceived Stress Scale in a community sample of older adults. Int J Geriatr Psychiatry. 2014 Jun; 29(6):645-52.

publications  Berko ER, Suzuki M, Beren F, Lemetre C, Alaimo CM, Calder RB, Ballaban-Gil K, Gounder B, Kampf K, Kirschen J, Maqbool SB, Momin Z, Reynolds DM, Russo N, Shulman L, Stasiek E, Tozour J, Valicenti-McDermott M, Wang S, Abrahams BS, Hargitai J, Inbar D, Zhang Z, Buxbaum JD, Molholm S, Foxe JJ, Marion RW, Auton A, Greally JM. Mosaic epigenetic dysregulation of ectodermal cells in autism spectrum disorder. PLoS Genet. 2014 May 29; 10(5):e1004402.

publications  Sussman-Fort J, Sussman E. The effect of stimulus context on the buildup to stream segregation. Front Neurosci. 2014 Apr 29; 8:93. doi: 10.3389/fnins.2014.00093

publications Díaz-Balzac CA, Vázquez-Figueroa LD, García-Arrarás JE. Novel markers identify nervous system components of the holothurian nervous system. Invert Neurosci. 22014 Sep; 14(2):113-25.

publications Koellhoffer JF, Dai Z, Malashkevich VN, Stenglein MD, Liu Y, Toro R, Harrison J, Chandran K, Derisi JL, Almo SC, Lai JR. Structural Characterization of the Glycoprotein GP2 Core Domain from the CAS Virus, a Novel Arenavirus-Like Species. J Mol Biol. 2014 Apr 3; 426(7):1452-68.

publications  Nicholas MP, Rao L, Gennerich A. An improved optical tweezers assay for measuring the force generation of single Kinesin molecules. Methods Mol Biol. 2014; 1136:171-246.

publications  Nicholas MP, Rao L, Gennerich A. Covalent immobilization of microtubules on glass surfaces for molecular motor force measurements and other single-molecule assays. Methods Mol Biol. 2014; 1136:137-69.

publications  Koellhoffer JF, Dai Z, Malashkevich VN, Stenglein MD, Liu Y, Toro R, Harrison J, Chandran K, Derisi JL, Almo SC, Lai JR. Structural Characterization of the Glycoprotein GP2 Core Domain from the CAS Virus, a Novel Arenavirus-Like Species. J Mol Biol. 2014 Apr 3; 426(7):1452-1468.

publications  Gombar S, Maccarthy T, Bergman A. Epigenetics decouples mutational from environmental robustness. Did it also facilitate multicellularity? PLoS Comput Biol. 2014 Mar 6; 10(3):e1003450.

publications Mukhopadhyay A, Quiroz JA, Wolkoff AW. Rab1a Regulates Sorting of Early Endocytic Vesicles. Am J Physiol Gastrointest Liver Physiol. 2014 Mar; 306(5):G412-24.

publicationsSchneider JL, Cuervo AM. Liver autophagy: much more than just taking out the trash. Nat Rev Gastroenterol Hepatol. 2014 Mar; 11(3):187-200.

publications Patterson CA, Duijnhouwer J, Wissig SC, Krekelberg B, Kohn A. Similar adaptation effects in primary visual cortex and area MT of the macaque monkey under matched stimulus conditions. J Neurophysiol. 2014 Mar; 111(6):1203-13.

publications Patterson CAWissig SC, Kohn A. Adaptation disrupts motion integration in the primate dorsal stream. Neuron. 2014 Feb 5; 81(3):674-86.

publications Heim AE, Hartung O, Rothhämel S, Ferreira E, Jenny A, Marlow FL. Oocyte polarity requires a Bucky ball-dependent feedback amplification loop. Development. 2014 Feb; 141(4):842-54.

publications Shemesh A, Abdulla A, Yang F, Chua SC, Pessin JE, Zong H. The antidepressant trans-2-phenylcyclopropylamine protects mice from high-fat-diet-induced obesity. PLoS One. 2014 Feb 21; 9(2):e89199.

publications Portulano C, Paroder-Belenitsky M, Carrasco N. The Na+/I- Symporter (NIS): Mechanism and Medical Impact. Endocr Rev. 2014 Feb; 35(1):106-49.

publications Arora P, Baena A, Yu KO, Saini NK, Kharkwal SS, Goldberg MF, Kunnath-Velayudhan S, Carreño LJ, Venkataswamy MM, Kim J, Lazar-Molnar E, Lauvau G, Chang YT, Liu Z, Bittman R, Al-Shamkhani A, Cox LR, Jervis PJ, Veerapen N, Besra GS, Porcelli SA. A Single Subset of Dendritic Cells Controls the Cytokine Bias of Natural Killer T Cell Responses to Diverse Glycolipid Antigens. Immunity. 2014 Jan 16; 40(1):105-16.

publications Weiss CN, Ito K. DNA damage response, redox status and hematopoiesis. Blood Cells Mol Dis. 2014 Jan; 52(1):12-8.

publications Briggs SW, Mowrey W, Hall CB, Galanopoulou AS. CPP-115, a vigabatrin analogue, decreases spasms in the multiple-hit rat model of infantile spasms. Epilepsia. 2014 Jan; 55(1):94-102.

publications Koellhoffer JF, Higgins CD, Lai JR. Protein engineering strategies for the development of viral vaccines and immunotherapeutics. FEBS Lett. 2014 Jan 21; 588(2):298-307.

publications Ayers EI, Tow AC, Holtzer R, Verghese J. Walking while Talking and Falls in Aging. Gerontology.2014; 60(2):108-13.


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