Recent News
Teaming Up to Bring Life-Saving Immunotherapy to Cancer Patients Montefiore’s IHC Laboratory and Clinical Oncology Team Up to Bring PD-L1 Testing for Cancer Immunotherapy In-House
Visualizing the Immune Response Einstein Researchers Uncover Early Events in Severe Malaria Via Real-Time Video
Joining Forces to Validate a Novel Biomarker for Breast Cancer Metastasis. In December 2016, Joseph Sparano, MD, associate chair of medical oncology at the Montefiore Einstein Center for Cancer Care, presented an invited paper at the 39th San Antonio Breast Cancer Symposium in San Antonio, TX. Dr. Sparano reported on a study he led to clinically validate MetaSite (MS), a novel biomarker for metastasis in breast cancer. Joining him were two of his coauthors, Joan Jones, MD, and Maja Oktay, MD,PhD—both members of the Montefiore/Einstein Department of Pathology and Einstein’s Department of Anatomy & Structural Biology.
COMMENTARIES IN THE NEWS
Michael Prystowsky, MD, PhD, “The People Have Spoken,” Archives of Pathology, February 2017.read the full article
Dr. Prystowsky is also featured “An Ocean Apart,” a Q & A with leading British and American leaders in the field, on the role of pathology and pathologists. The Pathologist, January 2017.read the full article
James Pullman, MD, PhD, and Jonathan Nylk, PhD, “Finely Tuned Microscopy,” The Pathologist, December 2016. read the full article
RECENT GRANTS
Louis Weiss, MD, MPH, was awarded a $2.1 million, five-year grant by the National Institute of Allergy and Infectious Diseases (NIAID) to continue his efforts to understand how microsporidia—a type of single-celled parasite--infects host cells via a unique invading structure called the polar tube. read more
David Fooksman, PhD, and
Gregoire Lauvau, PhD, received a two-year $250,000 R21 grant from the NIAID to continue their groundbreaking use of in vivo video to shed light on the type 1 interferon pathway, an inflammatory signal that appears to play a pivotal role in severe malaria. (For details, see in Published Research and Cross-Campus Collaborations.)
Fernando Macian-Juan, MD, PhD, has received a five-year, $2 million grant from the NIAID to study how chaperone-mediated autophagy (CMA) in T cells regulates the cells’ function. CMA is a degradation system that cells use to break down and recycle their proteins.
read more
Rachel Hazan, PhD, has received a one-year, $300,000 grant renewal from the Avon Foundation to continue leading a study on the role of cell cycle inhibitor P21 in triple-negative breast cancer, with a focus on metastatic disease. Her project collaborators are
Susan Fineberg, MD, and
Joseph Sparano, MD.
Research
Experimental pathology aims to define disease in terms of fundamental molecular and cellular processes. Research in our Department is focused on critical issues in multiple disease classes. Areas of focus include
Research in each of these areas is highly interactive, and the Department strives for a collegial atmosphere in which collaborations can flourish. This effort is conducted through a variety of department-level activities, including regular meetings to discuss work in progress and a departmental retreat at which students, postdoctoral fellows, residents and faculty all have opportunity to present and discuss their research.
Research Funding Program
The Department of Pathology has established a research funding program to encourage residents and fellows to participate in clinical pilot research projects. Up to $2,000 will be awarded per research project, for projects of up to two years in duration.
Research Faculty
Amanda Beck, DVM
Geoffrey Childs, PhD
Joan W. Berman, PhD
Mahalia Desruisseaux, MD, PhD
Amy Fox, MD
David Fooksman, PhD
Rachel Hazan, PhD
Lawrence Herbst, DVM, PhD
Huan Huang, MD
Sunhee C. Lee, MD
Fernando Macian, MD, PhD
Maja Oktay, MD, PhD
Harry Ostrer, MD
Thomas J. Ow, MD
Michael B. Prystowsky, MD, PhD
Moshe Sadofsky, MD, PhD
Laura Santambrogio, MD, PhD
Bridget Shafit-Zagardo, PhD
Herbert Tanowitz, MD
Louis Weiss, MD