Department of Pathology News

Spring 2017 Main Page

Monday, May 01, 2017

Recent News 



ZhuHalmos-microscope Teaming Up to Bring Life-Saving Immunotherapy to Cancer Patients Montefiore’s IHC Laboratory and Clinical Oncology Team Up to Bring PD-L1 Testing for Cancer Immunotherapy In-House



Fooksman Visualizing the Immune Response Einstein Researchers Uncover Early Events in Severe Malaria Via Real-Time Video



 



MayaJoining Forces to Validate a Novel Biomarker for Breast Cancer Metastasis. In December 2016, Joseph Sparano, MD, associate chair of medical oncology at the Montefiore Einstein Center for Cancer Care, presented an invited paper at the 39th San Antonio Breast Cancer Symposium in San Antonio, TX. Dr. Sparano reported on a study he led to clinically validate MetaSite (MS), a novel biomarker for metastasis in breast cancer. Joining him were two of his coauthors, Joan Jones, MD, and Maja Oktay, MD,PhD—both members of the Montefiore/Einstein Department of Pathology and Einstein’s Department of Anatomy & Structural Biology.



 



COMMENTARIES IN THE NEWS



Michael Prystowsky Michael Prystowsky, MD, PhD, “The People Have Spoken,” Archives of Pathology, February 2017.read the full article 



 



 



Michael PrystowskyDr. Prystowsky is also featured “An Ocean Apart,” a Q & A with leading British and American leaders in the field, on the role of pathology and pathologists. The Pathologist, January 2017.read the full article  



 



James PullmanJames Pullman, MD, PhD, and Jonathan Nylk, PhD, “Finely Tuned Microscopy,” The Pathologist, December 2016. read the full article 




 



RECENT GRANTS



louis-weissLouis Weiss, MD, MPH, was awarded a $2.1 million, five-year grant by the National Institute of Allergy and Infectious Diseases (NIAID) to continue his efforts to understand how microsporidia—a type of single-celled parasite--infects host cells via a unique invading structure called the polar tube. read more 


 


DavidFooksmanDavid Fooksman, PhD, and Gregoire Lauvau, PhD, received a two-year $250,000 R21 grant from the NIAID to continue their groundbreaking use of in vivo video to shed light on the type 1 interferon pathway, an inflammatory signal that appears to play a pivotal role in severe malaria. (For details, see in Published Research and Cross-Campus Collaborations.)

 



FernandoFernando Macian-Juan, MD, PhD, has received a five-year, $2 million grant from the NIAID to study how chaperone-mediated autophagy (CMA) in T cells regulates the cells’ function. CMA is a degradation system that cells use to break down and recycle their proteins.read more  

 



RachelRachel Hazan, PhD, has received a one-year, $300,000 grant renewal from the Avon Foundation to continue leading a study on the role of cell cycle inhibitor P21 in triple-negative breast cancer, with a focus on metastatic disease. Her project collaborators are Susan Fineberg, MD, and Joseph Sparano, MD.


Research



Experimental pathology aims to define disease in terms of fundamental molecular and cellular processes. Research in our Department is focused on critical issues in multiple disease classes. Areas of focus include 





Research in each of these areas is highly interactive, and the Department strives for a collegial atmosphere in which collaborations can flourish. This effort is conducted through a variety of department-level activities, including regular meetings to discuss work in progress and a departmental retreat at which students, postdoctoral fellows, residents and faculty all have opportunity to present and discuss their research.



Research Funding Program



The Department of Pathology has established a research funding program to encourage residents and fellows to participate in clinical pilot research projects. Up to $2,000 will be awarded per research project, for projects of up to two years in duration.



Research Faculty



Amanda Beck, DVM 



Geoffrey Childs, PhD 



Joan W. Berman, PhD 



Mahalia Desruisseaux, MD, PhD 



Amy Fox, MD  



David Fooksman, PhD  



Rachel Hazan, PhD 



Lawrence Herbst, DVM, PhD 



Huan Huang, MD 



Sunhee C. Lee, MD  



Fernando Macian, MD, PhD 



Maja Oktay, MD, PhD 



Harry Ostrer, MD 



Thomas J. Ow, MD 



Michael B. Prystowsky, MD, PhD 



Moshe Sadofsky, MD, PhD 



Laura Santambrogio, MD, PhD 



Bridget Shafit-Zagardo, PhD 



Herbert Tanowitz, MD 



Louis Weiss, MD 



















































































 


 




AWARDS, HONORS & APPOINTMENTS



FernandoFernando Macian-Juan, MD, PhD, has been granted tenure in the Department of Pathology. Dr. Macian-Juan is a Professor of Pathology. The Macian-Juan laboratory studies the mechanisms that regulate the induction of T cell tolerance and exhaustion; reversal of tumor-induced T cell tolerance as an immunotherapeutic approach; autophagy and T cell function; and aging in the T cell compartment.

 



 



lauraLaura Santambrogio, MD, PhD, has been awarded tenure in the Department of Pathology. Dr. Santambrogio is a Professor of Pathology, of Microbiology & Immunology and of Orthopaedic Surgery. The Santambrogio laboratory investigates antigen processing and MHC class II presentation pathways; pathogenesis of autoimmune response to self antigens; analysis of the lymph formation and lymphatic transport.

 



 



mahaliaMahalia S. Desruisseaux, MD, has been named an Associate Professor of Pathology at Einstein. She also holds the title of Associate Professor of Medicine (Infectious Diseases). Dr. Desruisseaux’s research focus is cerebral malaria: mechanisms of longterm cognitive dysfunction; regulation and activation of vasoactive mediators; and on modulators of blood-brain barrier impairment, and of neuronal and glial cell dysfunction.

Wendy Szymczak, PhD, has been appointed Associate Director of the Clinical Microbiology Laboratory at Montefiore. Dr. Szymczak formerly served as assistant to Laboratory Director Michael Levi, PhD. She also holds the title of Assistant Professor of Pathology at Einstein. Prior to joining Montefiore, Dr. Szymczak completed a post-doctoral research fellowship at Einstein in 2013. She earned her doctorate in molecular genetics, biochemistry & microbiology from the University of Cincinnati College of Medicine in 2010.

Emelia Cortez, Phlebotomy Laboratory manager, and her team, received a certificate of RESPECT in January for their outstanding efforts to ensure that patients in the Phlebotomy Unit at Montefiore’s Greene Medical Arts Pavilion received excellent care despite the challenges of a particularly stressful day. The honor, bestowed on the recommendation of grateful patients, recognizes service that “exemplifies the behaviors of the Montefiore Standards of Respect.”


 


RECENTLY PUBLISHED RESEARCH















 


Over the past year, research studies by Pathology Department faculty members have been published in prestigious, peer-reviewed scientific journals.

View a sampling of these articles here. 


 


TRAINEE SPOTLIGHT











  Gloria Ramos-Rivera, MD, chief resident of the Anatomic and Clinical Pathology Program at Montefiore, has been awarded the College of American Pathologists’s Ventana Fellowship. Funded by Ventana Medical Systems, the $5,000 grant will allow Dr. Ramos Rivera to participate in an advanced elective in translational diagnostics. She will travel to Tucson, AZ, in June, for the four-week training. Read more. 


 


 Decoding the Mysteries of a Lethal Parasite
Tatsuki Sugi, DVM, PhD, a postdoctoral researcher in the laboratory of Dr. Louis Weiss, is shedding light on the survival mechanism of Toxoplasma gondii. Read more. 


 


Exploring Low-Intensity Focused Ultrasound’s Potential as Cancer Immunotherapy
Karin Skalina, a predoctoral fellow in the laboratory of Dr. Chandan Guha, is investigating a new application of ultrasound as a non-invasive approach to cancer immunotherapy. Read more. 



Women’s March 2017: Montefiore Pathology Resident Stands Up for Social Justice
Elizabeth Richards, MD, describes her experience as a participant in the Women’s March in Washington, DC, and in a follow-up event in New York City. Read more. 



NEW FACES



We welcome Fabiane Matos dos Santos, PhD, a Visiting Scientist from the Federal University of Espirito Santo (FUES) in Brazil, and Sangeetha Thangaswamy, PhD,  from the Satara Univerity School of Chemical and Biotechnology in India.

Read about Drs. Matos dos Santos and Thangaswamy, and see the roster of our new Pathology residents here. 



 


Recent News 

         DrHerbertBTanowitz

Remembering Dr. Tanowitz

We mourn the passing of our beloved colleague, mentor and friend. [Read more]  

Announcing the Dr. Herbert B. Tanowitz Honorary Lecture for Parasitology and Tropical Medicine

Created by the Montefiore Einstein Department of Pathology in honor of Dr. Herbert Tanowitz who passed away on July 17, 2018, the lecture will focus on parasitology and tropical medicine—the driving research interests of Dr. Tanowitz’ long and distinguished career. The inaugural lecture will be a full-day symposium on the pathogenesis of Chagas Disease, including research on the role of adipose tissue in this chronic infection. 

Click here to donate to the Lecture Fund or for more information 

 

 Stemming Hepatitis in the Bronx 

 Yitz Goldstein, MD, assistant director, Montefiore Einstein Virology Laboratories, was featured with Sheila Reynoso, MPH, director, Montefiore Hep C Treatment Network, on the BronxNet TV show “Open,” on July 18. The interview, aimed at raising awareness of the “hidden epidemic” of Hepatitis B and Hepatitis C in New York City, was aired in connection with the global observance of World Hepatitis Day, July 28. Dr. Goldstein and Ms. Reynoso explained viral hepatitis; discussed the ongoing efforts of Montefiore pathologists and clinicians to diagnose, treat and prevent hepatitis in the Bronx community; and noted the services available at Montefiore. 

 View the interview here   

Amy S. Fox, MD, MS, director, Montefiore Einstein Virology Laboratories, and professor of Pathology at Einstein, and Jonathan M. Schwartz, MD, a member of the liver transplant team at Montefiore and professor of Medicine (Hepatology) at Einstein, co-authored an article aimed at informing residents of the Bronx community on practical steps to take for protection against viral hepatitis. The story was featured in the August 9 print and online editions of the Bronx Voice.

Read the article here 

 Research Retreat 2018

Panoramic views of the East River were the backdrop for this year’s Pathology Department Research Retreat, held on June 8 at Marina Del Ray in the Bronx. An enthusiastic crowd of pathology post-docs, PhD candidates, fellows and residents, along with their faculty mentors, converged on the venue to present, discuss and debate the merits of the trainees’ original research projects. [Read more] 

 Features  

 

AdamColeTiffanyHeberExciting Changes  to Our Pathology Residency Program 

 

 

ABaldwinCharting Her Own Course: From Navy Flight Surgeon to First-Year Pathology Resident 

 

mark-suhrlandMark Suhrland, MD, Blogs about See, Test & Treat and the Pathologist’s Expanding Role in Community-Based Healthcare 

 

 

 

kh-rameshBangalore to the Bronx: The Making of a Clinical and Molecular Cytogeneticist 

 

   

Awards, Honors & Appointments
[Read more]

 

Research

Experimental pathology aims to define disease in terms of fundamental molecular and cellular processes. Research in our Department is focused on critical issues in multiple disease classes. Areas of focus include 

Research in each of these areas is highly interactive, and the Department strives for a collegial atmosphere in which collaborations can flourish. This effort is conducted through a variety of department-level activities, including regular meetings to discuss work in progress and a departmental retreat at which students, postdoctoral fellows, residents and faculty all have opportunity to present and discuss their research.

Research Funding Program

The Department of Pathology has established a research funding program to encourage residents and fellows to participate in clinical pilot research projects. Up to $2,000 will be awarded per research project, for projects of up to two years in duration.

Research Faculty

Amanda Beck, DVM 

Geoffrey Childs, PhD 

Joan W. Berman, PhD 

Mahalia Desruisseaux, MD, PhD 

Amy Fox, MD  

David Fooksman, PhD  

Rachel Hazan, PhD 

Lawrence Herbst, DVM, PhD 

Huan Huang, MD 

Sunhee C. Lee, MD  

Fernando Macian, MD, PhD 

Maja Oktay, MD, PhD 

Harry Ostrer, MD 

Thomas J. Ow, MD 

Michael B. Prystowsky, MD, PhD 

Moshe Sadofsky, MD, PhD 

Laura Santambrogio, MD, PhD 

Bridget Shafit-Zagardo, PhD 

Louis Weiss, MD 

 

 
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