Department of Pathology

Department Faculty

Dr. Bradford K. Poulos, Ph.D.

Bradford K. Poulos, Ph.D.

Visiting Associate Professor, Dominick P. Purpura Department of Neuroscience

Professional Interests

This laboratory explores the effect of gangliosides on the development of the central nervous system.

The hydrophobic portion of gangliosides resides in the plasma membrane of cells while their hydrophilic, oligosaccharide, portion is exposed to the extracellular environment.  The composition of the oligosaccharide is thought to be important in intercellular interactions.  These interactions, found ubiquitously but specifically in neural synapse formation and central nervous system ontogeny, have never been directly observed.

This laboratory is characterizing a microfluidic system that will expose pluripotent cells, growing on rolling microbeads, to gangliosides fixed to the surface of micro-channels.  The type of ganglioside and duration of exposure will be varied to mimic natural systems.

Material in this section is provided by individual faculty members who are solely responsible for its accuracy and content.

Albert Einstein College of Medicine
Rose F. Kennedy Center
1410 Pelham Parkway South , Room 329F
Bronx, NY 10461

Tel: 718.430.2413
Fax: 718.430.8821

Research Information