Department of Orthopaedic Surgery

6th Annual Musculoskeletal Repair and Regeneration Symposium

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The Albert Einstein College of Medicine Musculoskeletal Repair and Regeneration Symposium seeks to expand the knowledge base within the field, and to foster creativity, collaboration and networking between researchers throughout the region. This year's meeting will emphasize recent advances in translational research in four areas:

   • Imaging and loading of the skeleton: From mouse to human
   • Cartilage: Development, pathologies, and repair
   • Tendon regeneration: From development to translation
   • Stem Cells in regenerative medicine


October 19, 2017
LeFrak Auditorium (Room 151)
Albert Einstein College of Medicine
1301 Morris Park Ave. Bronx, NY 10461


Online registration is closed.  Please register in person at the day of the Symposium.
Registration is free and includes continental breakfast, lunch, and reception.


AGENDA (tentative)

7:15 – 8:00am

Check-in and continental breakfast

8:00 – 8:10am

Introduction and acknowledgements 
Herb B. Sun, PhD

Opening remarks
Neil J. Cobelli, M.D.

Session 1: Imaging and loading of the skeleton: from mouse to human 

Steering Chair: X. Edward Guo, Ph.D.


Bone Mechanobiology: In Vivo Studies on the Role of Age, Wnt Signaling, and Cell Proliferation
Matthew Silva, Ph.D.
Washington University in St. Louis



Integration of Ultrasound Imaging and Therapeutics for Tissue Regeneration and Cellular Ca++ Excitation
Yi-Xian Qin, Ph.D.
Stony Brook University



In Vivo Mechanical Loading and Imaging in Mouse
Mitchell B. Schaffler, Ph.D.
The City College of New York


Perspectives of In Vivo Skeletal Imaging and Mechanical Loading in Humans
X. Edward Guo, Ph.D.
Columbia University


Coffee Break


Session 2: Cartilage: development, pathologies and repair 

Steering Chair: Maurizio Pacifici, Ph.D.



The Role of BMP Signaling in Joint Homeostasis
Vicki Rosen, Ph.D.
Harvard University



Novel Imaging Modalities for Assessment of Cartilage Pathology and Repair
Nancy Pleshko, Ph.D.
Temple University



Contribution of IKKalpha to Chondrocyte Hypertrophy and Cartilage Degradation in Osteoarthritis
Miguel Otero, Ph.D.
The Hospital for Special Surgery



Cells That Repair Cartilage: Synovium, Cartilage and/or Bone Marrow
Jeremy Mao, D.D.S., Ph.D.
Columbia University


Lunch and poster session 



Lunch and poster session
      Poster session starts at 12:45pm
12:00pm – Faculty photo
12:00-12:45pm – Faculty meeting with lunch

Session 3: Tendon Regeneration: From Development to Translation 

Steering Chair: Alice Huang, Ph.D.



Regulation of Tendon Growth and Maturation
Ronen Schweitzer, Ph.D.
Oregon Health & Science University



FGF Signaling in Enthesis Maturation
Megan Killian, Ph.D.
University of Delaware



Postnatal Tendon Growth and Remodeling Requires Platelet-Derived Growth Factor Receptor Signaling
Christopher Mendias, Ph.D. and Jacob Swanson
Hospital for Special Surgery



Tendon Regeneration by Harnessing Endogenous Stem Cells: From Small Molecules to Scaffolds
Chang Lee, Ph.D.
Columbia University



Coffee Break

Session 4: Stem Cells in Regenerative Medicine 

Steering Chairs: Jeremy Mao, D.D.S., Ph.D. and Catherine Kuo, Ph.D.



Embryonically Inspired Tendon Regeneration Approaches
Catherine Kuo, Ph.D.
University of Rochester



Novel TNFR2 Bone Regeneration Signaling
Chuanju Liu, Ph.D.
New York University



Designing Tissue-Mimetic Niches for Stem Cell Mediated Cartilage and Bone Regeneration
Stephanie Bryant, Ph.D.
University of Colorado



Delivery strategies for increasing endogenous progenitor cells for bone defect healing
Liisa Kuhn, Ph.D.
University of Connecticut


Annulus fibrosus repair in a large animal model
James Iatridis, Ph.D.
Icahn School of Medicine at Mount Sinai

Young Investigator Awards / Reception 



Young Investigator Awards
Chair: Mia M. Thi, PhD


Closing remarks
Neil J. Cobelli, MD

5:45pm – 6:15pm

Reception and networking



Hui B. Sun, PhD - Program Director

Steering Commitee Chairs
• X. Edward Guo, PhD
• Maurizio Pacifici, PhD
• Alice Huang, MD
• Jeremy Mao, DDS, PhD
• Catherine Kuo, PhD

Program Overseers
• Di Chen, MD, PhD
• Michael Detamore, PhD
• Susannah Fritton, PhD
• Mary Goldring, PhD
• Steven Goldring, MD
• Ed Guo, PhD
• John Hardin, MD
• David Hirsh, MD
• James Iatridis, PhD
• Lionel Ivashkiv, MD
• Thorsten Kirsch, PhD
• Chuanju Liu, PhD
• Helen Lu, PhD
• Jeremy Mao, DDS, PhD
• Steven Nicoll, PhD
• Maurizio Pacifici, PhD
• Nicola Patridge, PhD
• Clint Rubin, PhD
• Yi-Xian Qin, PhD
• Mitchell Schaffler, PhD
• David Spray, PhD
• Stavros Thomopoulos, PhD

Poster Session and Young Investigator Award Committee
• Chair: Mia Thi, PhD

• Co-chair: Di Chen, MD, PhD
• Co-chair: Regina Hanstein, PhD
• Co-chair: David Hirsh, MD
• Co-chair: Bang Hoang, MD
• Co-chair: Robert J. Majeska, PhD
• Co-chair: Sylvia O. Suadicani, PhD 


Poster Session - We invite investigators to submit abstracts for the poster session, which is an important component of this conference. Posters will be displayed throughout the day with a dedicated poster session. Young Investigator Award Abstracts from students at all training levels and postdoctoral fellows will be considered for Young Investigator Awards. Three winners will be announced and each will be presented with prize and a plaque during the evening session. Winners will have the opportunity to give a brief highlight of their work (2 minutes) at the end of the award ceremony.

To qualify, you must register and submit an abstract to Dr. Mia Thi, the chair of the Poster Session and Young Investigator Award committee, by September 25, 2017 via email to: 

The abstract is limited to 1 page. Include in your abstract the study's objective, a brief statement of methods, a summary of the results obtained, conclusions, and significance. Please follow the template here. As the Symposium aims to promote communication within our region, we encourage you to submit your recent work (within 2017) to this Symposium, including work that may have been submitted to other meetings.


Damage to musculoskeletal tissues is a significant cause of morbidity and increased mortality, and is a magnifier of mortality in other clinical diseases such as diabetes and cardiovascular disorders. The innate repair capacities are limited for articular cartilage, tendon, and extensive bone defects. In addition, current treatments for the repair of injured musculoskeletal tissue are not sufficient to restore the functionality of the original tissue. These daunting challenges present a desperate need for a better understanding of musculoskeletal biology and emphasize the importance of discovering novel repair and regeneration strategies that can be translated to clinical use.


This program will address current issues in musculoskeletal repair and regeneration, and disease treatment. Discussions will focus on up-to-date laboratory discoveries and the potential impact of these findings on patient treatment and management in the future.


Herb B. Sun, PhD
 Program Director
 P: 718-430-4291
 F: 718-430-3259 

Mia M. Thi, PhD
 Chair, Poster Session and Young Investigator
 Award Committee
 P: 718-430-3460 

Rhomina Carrasco
 Symposium Coordinator
 P: 718-430-2911 

Residence Inn by Marriott
The Bronx at Metro Center Atrium
1776 Eastchester Road, Bronx, NY 10461
Launched in May 2015, the hotel is a 10 minute walk from the Symposium. 
P: 718-239-3939

The PF Parking lot
1975 Eastchester Road
Bronx, NY 10461 



Neil J. Cobelli, M.D.
Tel: 347.577.4450
Fax: 347.577.4451


Anna Cioffi
Tel: 718.430.2911


Department Office

Montefiore Medical Center
1250 Waters Place
11th floor
Bronx, NY 10461

Tel: 347.577.4450

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