Department of Orthopaedic Surgery

8th Annual Musculoskeletal Repair and Regeneration Symposium

SYMPOSIUM MISSION 

The Albert Einstein College of Medicine Musculoskeletal Repair and Regeneration Symposium seeks to expand the knowledge base within the field, and to foster creativity, collaboration and networking between researchers throughout the region. This year's meeting will emphasize recent advances in translational research in four areas:

   • Current concepts in musculoskeletal joint diseases and treatments
   • "Hot topics" in bone
   • Muscle pathology seen in the setting of tendon injury
   • Tissue Repair and Regeneration and Immune Modulation
 

CONFERENCE LOCATION AND DATE  

October 3, 2019
LeFrak Auditorium (Room 151)
Albert Einstein College of Medicine
1301 Morris Park Ave. Bronx, NY 10461
Directions: http://www.einstein.yu.edu/visitors/   


REGISTRATION

Registration is free and includes continental breakfast, lunch, and reception.
Online registration is now closed. Please register onsite.

AGENDA 

7:15 – 8:00am

Check-in and continental breakfast

8:00 – 8:10am

Introduction and acknowledgements 
Hui (Herb) B. Sun, PhD

Opening remarks
Neil J. Cobelli, M.D.

Session 1: Current Concepts in Musculoskeletal Joint Diseases and Treatment 

Steering Chair: Chuanju Liu, Ph.D.

8:10-8:15am

Introduction
Chuanju Liu, Ph.D.
New York University

8:15-8:35am

Inflammatory regulation of bone injury and repair
Lionel B. Ivashkiv, M.D.
Hospital for Special Surgery

8:35-8:55am

 

Purine nucleotides, nucleosides, inflammaging and osteoarthritis
Bruce N. Cronstein, M.D.
New York University

8:55-9:15am

 

Substrate-identification for the ADAMTS17 protease and its role in Weill-Marchesani-like syndrome
Dirk Hubmacher, Ph.D.
Icahn School of Medicine at Mount Sinai

9:15-9:35am

Biomaterials strategies to modulate inflammation for tissue repair
Kam W. Leong, Ph.D.
Columbia University

9:35-9:40am

Discussion / Conclusions
 

9:40-10:00am

Coffee Break
 

Session 2: "Hot topics" in Bone 

Steering Chair: J. Christopher Fritton, Ph.D.

10:00-10:05am

 

Introduction
J. Christopher Fritton, Ph.D.
The City College of New York

10:05-10:25am

 

Of aging mice and humans: Osteocytes, connections, and communication
Mitchell B. Schaffler, Ph.D.
City College of New York

10:25-10:40pm

Effects of Somatopause on the Aging Skeleton
Shoshana Yakar, Ph.D.
New York University

10:45-11:05am

 

Malignant osteogenesis: Leveraging tumor suppressor deficiency for proteosome-based therapy 
Bang H. Hoang, M.D.
Montefiore Medical Center

11:05-11:25am

 

How does mechanical loading build bone microstructure: Modeling vs. remodeling?
X. Edward Guo, Ph.D.
Columbia University

11:25-11:30am

 

Discussion / Conclusions  

Lunch and poster session 

11:35 - 11:45am
11:45 - 12:30pm
11:45 - 1:55pm
 

Group photos (Courtyard in front of Lubin Hall)
Faculty photo meeting with lunch (Faculty club in Lubin Hall)
Lunch and poster session (Lubin Hall) 
 

Session 3: Muscle Pathology Seen in the Setting of Tendon Injury 

Steering Chair: Scott A. Rodeo, M.D.

2:00-2:05pm

 

Introduction
Scott A. Rodeo, M.D.
Hospital for Special Surgery

2:05-2:25pm

 

The clinical problem of muscle atrophy and fatty infiltration in rotator cuff injury
Brian T. Feeley, M.D.
University of California, San Francisco

2:25-2:45pm

 

Impaired muscle growth and regeneration in chronic rotator cuff tears
Samuel R. Ward, M.D.
University of California, San Diego

2:45-3:05pm

 

Targeted control of skeletal muscle contraction and tendon loading using optogenetics
Megan L. Killian, Ph.D.
University of Delaware

3:05-3:25pm

 

Mitochondrial dysfunction in tendon and muscle
Scott A. Rodeo, M.D.
Hospital for Special Surgery

3:25-3:30pm

Discussion / Conclusions
 

3:30-3:50pm Coffee Break
 

Session 4: Tissue Repair and Regeneration and Immune Modulation 

Steering Chair: Helen H. Lu, Ph.D.

3:50-3:55pm

Introduction
Helen H. Lu, Ph.D.
Columbia University

3:55-4:15pm

 

Pseudotime kinetic analysis of inflammation and immune modulatory treatment in soft tissue injuries
Edward A. Botchwey, Ph.D.
Georgia Institute of Technology

4:15-4:35pm

 

Engineering new biologic therapies for arthritis
Farshid Guilak, Ph.D.
Washington University in St Louis

4:35-4:55pm

 

Engineering Materials for Immunomodulation in Osteoarthritis
Ankur Singh, Ph.D.
Cornell University

4:55-5:15pm

 

Immune regulation of tendon regeneration
Alice H. Huang, Ph.D.
Icahn School of Medicine at Mount Sinai

5:15-5:20pm

Discussion / Conclusions 

 

5:20-5:25pm Break
 

Young Investigator Awards / Reception 

5:25pm

 

Young Investigator Awards
Hosted by:Poster Session and Young Investigator Award Committee
Chair: Mia M. Thi, PhD

5:50pm

Closing remarks
Neil J. Cobelli, MD

6:00pm

Reception and networking

 

PROGRAM COMMITTEE 

Hui (Herb) B. Sun, PhD - Program Director

Steering Committee Chairs
• Chuanju Liu, PhD
• Scott A. Rodeo, MD
• J. Christopher Fritton, PhD
• Helen H. Lu, PhD

Program Overseers
• Di Chen, MD, PhD
• Michael Detamore, PhD
• Susannah Fritton, PhD
• Mary Goldring, PhD
• Steven Goldring, MD
• Ed Guo, PhD
• John Hardin, MD
• David Hirsh, MD
• James Iatridis, PhD
• Lionel Ivashkiv, MD
• Thorsten Kirsch, PhD
• Catherine Kuo, PhD
• Chuanju Liu, PhD
• Helen Lu, PhD
• Jeremy Mao, DDS, PhD
• Steven Nicoll, PhD
• Maurizio Pacifici, PhD
• Nicola Patridge, PhD
• Clint Rubin, PhD
• Yi-Xian Qin, PhD
• Mitchell Schaffler, PhD
• David Spray, PhD
• Stavros Thomopoulos, PhD
 

Poster Session and Young Investigator Award Committee
• Chair: Mia Thi, PhD
• Co-chairs:
  Di Chen, MD, PhD
  David Corr, PhD
  Ed Guo, PhD
  Regina Hanstein, PhD
  David Hirsh, MD
  Bang Hoang, MD, MD
  Robert J. Majeska, PhD
  Jeremy Mao, DDS, PhD, PhD
  Maurizio Pacifici, PhD
  Yi-Xian Qin, PhD
  Sylvia O. Suadicani, PhD

CALL FOR ABSTRACTS / YOUNG INVESTIGATOR AWARD 

Poster Session - We invite investigators to submit abstracts for the poster session, which is an important component of this conference. Posters will be displayed throughout the day with a dedicated poster session. Young Investigator Award Abstracts from students at all training levels and postdoctoral fellows will be considered for Young Investigator Awards. Three winners will be announced and each will be presented with prize and a plaque during the evening session. Winners will have the opportunity to give a brief highlight of their work (2 minutes) at the end of the award ceremony.

To qualify, you must register and submit an abstract to Dr. Mia Thi, the chair of the Poster Session and Young Investigator Award committee, by September 16, 2019 via email to: mia.thi@einstein.yu.edu. 

The abstract is limited to 1 page. Include in your abstract the study's objective, a brief statement of methods, a summary of the results obtained, conclusions, and significance. Please follow the template here. As the Symposium aims to promote communication within our region, we encourage you to submit your recent work (within 2019) to this Symposium, including work that may have been submitted to other meetings.

STATEMENT OF NEED  

Damage to musculoskeletal tissues is a significant cause of morbidity and increased mortality, and is a magnifier of mortality in other clinical diseases such as diabetes and cardiovascular disorders. The innate repair capacities are limited for articular cartilage, tendon, and extensive bone defects. In addition, current treatments for the repair of injured musculoskeletal tissue are not sufficient to restore the functionality of the original tissue. These daunting challenges present a desperate need for a better understanding of musculoskeletal biology and emphasize the importance of discovering novel repair and regeneration strategies that can be translated to clinical use.

GOALS  

This program will address current issues in musculoskeletal repair and regeneration, and disease treatment. Discussions will focus on up-to-date laboratory discoveries and the potential impact of these findings on patient treatment and management in the future.

CONTACT INFORMATION 

Hui (Herb) B. Sun, PhD
 Program Director
 Email: herb.sun@einstein.yu.edu
 P: 718-430-4291
 F: 718-430-3259 

Mia M. Thi, PhD
 Chair, Poster Session and Young Investigator
 Award Committee
 Email: mia.thi@einstein.yu.edu
 P: 718-430-3460 

Rhomina Carrasco
 Symposium Coordinator
 Email: rhomina.carrasco@einstein.yu.edu
 P: 718-430-2911 

HOTEL INFORMATION 
Residence Inn by Marriott
The Bronx at Metro Center Atrium
1776 Eastchester Road, Bronx, NY 10461
Launched in May 2015, the hotel is a 10 minute walk from the Symposium.
http://cwp.marriott.com/nycbx 
P: 718-239-3939

PARKING INFORMATION  
The Kwik Park Parking lot
1975 Eastchester Road
Bronx, NY 10461

 

Chair:

Neil J. Cobelli, M.D.
neil.cobelli@einstein.yu.edu
Tel: 347.577.4450
Fax: 347.577.4451

Administrator

Anna Cioffi
anna.cioffi@einstein.yu.edu
Tel: 718.430.2911

 

Department Office

Montefiore Medical Center
1250 Waters Place
11th floor
Bronx, NY 10461

Tel: 347.577.4450
Fax:
347.577.4451

 
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