Spotlight

Dominick P. Purpura Department of Neuroscience

Animal Behavior Core

Go to the Behavioral Core Website 

     The Behavioral Core provides expertise, staff and state-of-the-art equipment and software designed for testing behavioral outcome in rodents. The Core also maintains the strictest standards with regards to validity and reliability of behavioral assays andtraining. We facilitate functional assessments and phenotyping with many type of logistical support including help with animal protocols, grant and manuscript writing, experimental design and statistical analysis. We have many well-characterized assays, and we also develop tests to suit individual needs and other species.

Contact: Maria Gulinello, Ph.D
Kennedy 925, B32, B34
tel. 718-430-4042

Cognitive Function
  • Visual Working Memory - Object Recognition
  • Spatial Working Memory -Object Placement
  • Social Discrimination Memory
  • Spontaneous Alternation
  • Morris Water Maze
  • Radial Arm Maze (reference and working memory)
  • Conditioned Taste Aversion

Affective / Emotional Behaviors
  • Social Interaction Social Preference
  • Social Transmission of Food Preferences
  • Reproductive and mating behavior
  • Open Field (exploratory behavior, risk assessment, thigmotaxis)
  • Marble Burying (neophobia, compulsions)
  • Elevated Plus Maze (anxiety)
  • Light/Dark Box (anxiety)
  • Acoustic Startle – anxiety and hearing
  • Porsolt (Forced Swim) Test – depression
 
Tests of Analgesia
  • Von Frey (sensory threshold and allodynia)

Sensorimotor Function
  • Open Field (activity, habituation, sensitization)
  • Rotarod (motor coordination, motor learning)
  • Grip Strength (sensorimotor function, muscle strength)
  • Gait analysis and toe spread (motor coordination)
  • Balance Beam (motor coordination)
  • Visual Placing (visual acuity)
  • Visual Cliff (visual acuity and depth perception)
  • Pupil dilation
  • Acoustic Startle and Prepulse Inhibition

Other
  • Functional Observation Battery (Primary Screen)
  • Estrous Cycle Staging
  • Ultrasonic vocalizations (coming soon)
  • Behavioral Tracking software (Viewer, Biobserve)
  • Conditioned Place Preferences and Aversions
  • Grooming
  • Stereotypies
  • Developmental milestones
 
 
 

Recent News & Events

Grant Award | Dr. Noboru Hiroi
Noboru Hiroi, Ph.D., has been awarded a five-year, $1.8 million grant from the National Institute on Deafness and Other Communication Disorders to investigate the interplay among genes, early social communication and neonatal maternal care in determining the severity of autism spectrum disorder (ASD). Working with a genetic mouse model of ASD, Dr. Hiroi’s lab has observed that newborn mice display an unusual vocalization or “call,” to communicate with their mothers and that this abnormal call reduces the level of maternal care that newborns receive. The researchers will study whether abnormal newborn-to-mother vocalization is caused by ASD-related gene variants and whether this early experience of social communication gone awry worsens ASD-like behaviors through the epigenetic modification of these gene variants. Dr. Hiroi is professor in the Dominick P. Purpura Department of Neuroscience and of psychiatry and behavioral sciences. (1R01DC015776-01A1)...more

Publication | Dr. Yonatan Fishman, Dr. Mitchell Steinschneider
Drs. Yonatan Fishman, Dr. Mitchell Steinschneider and collaborators recently published "A Crucial Test of the Population Separation Model of Auditory Stream Segregation in Macaque Primary Auditory Cortex" in J Neurosci. 37(44):10645-55, 2017....more

more news and events

 

Contact Us

Rose F. Kennedy Center

1410 Pelham Parkway South

9th Floor

Bronx, NY 10461

Phone: 718-430-2408

Fax: 718-430-8821

 
 
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