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Cook, I. T., T. S. Leyh, S. A. Kadlubar, and C. N. Falany. 2010. Lack of substrate inhibition in a monomeric form of human cytosolic SULT2A1. Horm Mol Biol Clin Investig 3:357-366
Jain, N., B. L. Wickes, S. M. Keller, J. Fu, A. Casadevall, P. Jain, M. A. Ragan, U. Banerjee, and B. C. Fries. 2005. Molecular epidemiology of clinical Cryptococcus neoformans strains from India. J Clin Microbiol 43:5733-5742
Guerrero, A., N. Jain, D. L. Goldman, and B. C. Fries. 2006. Phenotypic switching in Cryptococcus neoformans. Microbiology 152:3-9
Jain, N., A. Guerrero, and B. C. Fries. 2006. Phenotypic switching and its implications for the pathogenesis of Cryptococcus neoformans. FEMS Yeast Res 6:480-488
Jain, N., L. Li, D. C. McFadden, U. Banarjee, X. Wang, E. Cook, and B. C. Fries. 2006. Phenotypic switching in a Cryptococcus neoformans variety gattii strain is associated with changes in virulence and promotes dissemination to the central nervous system. Infect Immun 74:896-903
Jain, N., R. Kohli, E. Cook, P. Gialanella, T. Chang, and B. C. Fries. 2007. Biofilm formation by and antifungal susceptibility of Candida isolates from urine. Appl Environ Microbiol 73:1697-1703
Jain, N., and B. C. Fries. 2008. Phenotypic switching of Cryptococcus neoformans and Cryptococcus gattii. Mycopathologia 166:181-188
Jain, N., F. Hasan, and B. C. Fries. 2008. Phenotypic switching in fungi. Curr Fungal Infect Rep 2:180-188
Hasan, F., I. Xess, X. Wang, N. Jain, and B. C. Fries. 2009. Biofilm formation in clinical Candida isolates and its association with virulence. Microbes Infect 11:753-761
Jain, N., E. Cook, I. Xess, F. Hasan, D. Fries, and B. C. Fries. 2009. Isolation and characterization of senescent Cryptococcus neoformans and implications for phenotypic switching and pathogenesis in chronic cryptococcosis. Eukaryot Cell 8:858-866
Jain, N., and B. C. Fries. 2009. Antigenic and phenotypic variations in fungi. Cell Microbiol 11:1716-1723
Jain, N., L. Li, Y. P. Hsueh, A. Guerrero, J. Heitman, D. L. Goldman, and B. C. Fries. 2009. Loss of allergen 1 confers a hypervirulent phenotype that resembles mucoid switch variants of Cryptococcus neoformans. Infect Immun 77:128-140
Guerrero, A., N. Jain, X. Wang, and B. C. Fries. 2010. Cryptococcus neoformans variants generated by phenotypic switching differ in virulence through effects on macrophage activation. Infect Immun 78:1049-1057.
Hofmeyer, K. A., H. Jeon, and X. Zang. 2011. The PD-1/PD-L1 (B7-H1) pathway in chronic infection-induced cytotoxic T lymphocyte exhaustion. J Biomed Biotechnol 2011:451694
Im, J. S., P. Arora, G. Bricard, A. Molano, M. M. Venkataswamy, I. Baine, E. S. Jerud, M. F. Goldberg, A. Baena, K. O. Yu, R. M. Ndonye, A. R. Howell, W. Yuan, P. Cresswell, Y. T. Chang, P. A. Illarionov, G. S. Besra, and S. A. Porcelli. 2009. Kinetics and cellular site of glycolipid loading control the outcome of natural killer T cell activation. Immunity 30:888-898
Venkataswamy, M. M., A. Baena, M. F. Goldberg, G. Bricard, J. S. Im, J. Chan, F. Reddington, G. S. Besra, W. R. Jacobs, Jr., and S. A. Porcelli. 2009. Incorporation of NKT cell-activating glycolipids enhances immunogenicity and vaccine efficacy of Mycobacterium bovis bacillus Calmette-Guerin. J Immunol 183:1644-1656
Hinchey, J., B. Y. Jeon, H. Alley, B. Chen, M. Goldberg, S. Derrick, S. Morris, W. R. Jacobs, Jr., S. A. Porcelli, and S. Lee. 2011. Lysine auxotrophy combined with deletion of the SecA2 gene results in a safe and highly immunogenic candidate live attenuated vaccine for tuberculosis. PLoS One 6:e15857
Sweeney, K. A., D. N. Dao, M. F. Goldberg, T. Hsu, M. M. Venkataswamy, M. Henao-Tamayo, D. Ordway, R. S. Sellers, P. Jain, B. Chen, M. Chen, J. Kim, R. Lukose, J. Chan, I. M. Orme, S. A. Porcelli, and W. R. Jacobs, Jr. 2011. A recombinant Mycobacterium smegmatis induces potent bactericidal immunity against Mycobacterium tuberculosis. Nat Med 17:1261-1268
Saidi M'Homa Soudja, Lauvau Lab
Campisi, L., S. M. Soudja, J. Cazareth, D. Bassand, A. Lazzari, F. Brau, E. Narni-Mancinelli, N. Glaichenhaus, F. Geissmann, and G. Lauvau. 2011. Splenic CD8α dendritic cells undergo rapid programming by cytosolic bacteria and inflammation to induce protective CD8 T-cell memory. Eur J Immunol 41:1594-1605
Madan, R. P., P. M. Mesquita, N. Cheshenko, B. Jing, V. Shende, E. Guzman, T. Heald, M. J. Keller, S. L. Regen, R. J. Shattock, and B. C. Herold. 2007. Molecular umbrellas: a novel class of candidate topical microbicides to prevent human immunodeficiency virus and herpes simplex virus infections. J Virol 81:7636-7646
Fakioglu, E., S. S. Wilson, P. M. Mesquita, E. Hazrati, N. Cheshenko, J. A. Blaho, and B. C. Herold. 2008. Herpes simplex virus downregulates secretory leukocyte protease inhibitor: a novel immune evasion mechanism. J Virol 82:9337-9344
Mesquita, P. M., S. S. Wilson, P. Manlow, L. Fischetti, M. J. Keller, B. C. Herold, and R. J. Shattock. 2008. Candidate microbicide PPCM blocks human immunodeficiency virus type 1 infection in cell and tissue cultures and prevents genital herpes in a murine model. J Virol 82:6576-6584
Mesquita, P. M., N. Cheshenko, S. S. Wilson, M. Mhatre, E. Guzman, E. Fakioglu, M. J. Keller, and B. C. Herold. 2009. Disruption of tight junctions by cellulose sulfate facilitates HIV infection: model of microbicide safety. J Infect Dis 200:599-608
Wilson, S. S., N. Cheshenko, E. Fakioglu, P. M. Mesquita, M. J. Keller, and B. C. Herold. 2009. Susceptibility to genital herpes as a biomarker predictive of increased HIV risk: expansion of a murine model of microbicide safety. Antivir Ther 14:1113-1124
Keller, M. J., P. M. Mesquita, N. M. Torres, S. Cho, G. Shust, R. P. Madan, H. W. Cohen, J. Petrie, T. Ford, L. Soto-Torres, A. T. Profy, and B. C. Herold. 2010. Postcoital bioavailability and antiviral activity of 0.5% PRO 2000 gel: implications for future microbicide clinical trials. PLoS One 5:e8781.
Herold, B. C., P. M. Mesquita, R. P. Madan, and M. J. Keller. 2011. Female genital tract secretions and semen impact the development of microbicides for the prevention of HIV and other sexually transmitted infections. Am J Reprod Immunol 65:325-333
Keller, M. J., R. P. Madan, N. M. Torres, M. J. Fazzari, S. Cho, S. Kalyoussef, G. Shust, P. M. Mesquita, N. Louissaint, J. Chen, H. W. Cohen, E. C. Diament, A. C. Lee, L. Soto-Torres, C. W. Hendrix, and B. C. Herold. 2011. A randomized trial to assess anti-HIV activity in female genital tract secretions and soluble mucosal immunity following application of 1% tenofovir gel. PLoS One 6:e16475
Mukherjee, G., and T. P. Dilorenzo. 2010. The immunotherapeutic potential of dendritic cells in type 1 diabetes. Clin Exp Immunol 161:197-207
Samanta, D., G. Mukherjee, U. A. Ramagopal, R. J. Chaparro, S. G. Nathenson, T. P. DiLorenzo, and S. C. Almo. 2011. Structural and functional characterization of a single-chain peptide-MHC molecule that modulates both naive and activated CD8+ T cells. Proc Natl Acad Sci USA 108:13682-13687
McClelland, E. E., A. M. Nicola, R. Prados-Rosales, and A. Casadevall. 2010. Ab binding alters gene expression in Cryptococcus neoformans and directly modulates fungal metabolism. J Clin Invest 120:1355-1361
Prados-Rosales, R., A. Baena, L. R. Martinez, J. Luque-Garcia, R. Kalscheuer, U. Veeraraghavan, C. Camara, J. D. Nosanchuk, G. S. Besra, B. Chen, J. Jimenez, A. Glatman-Freedman, W. R. Jacobs, Jr., S. A. Porcelli, and A. Casadevall. 2011. Mycobacteria release active membrane vesicles that modulate immune responses in a TLR2-dependent manner in mice. J Clin Invest 121:1471-1483
Siev, M., X. Yu, R. Prados-Rosales, F. T. Martiniuk, A. Casadevall, and J. M. Achkar. 2011. Correlation between serum and plasma antibody titers to mycobacterial antigens. Clin Vaccine Immunol 18:173-175
Dadachova, E., R. A. Bryan, C. Apostolidis, A. Morgenstern, T. Zhang, T. Moadel, M. Torres, X. Huang, E. Revskaya, and A. Casadevall. 2006. Interaction of radiolabeled antibodies with fungal cells and components of the immune system in vitro and during radioimmunotherapy for experimental fungal infection. J Infect Dis 193:1427-1436
Dadachova, E., T. Moadel, A. D. Schweitzer, R. A. Bryan, T. Zhang, L. Mints, E. Revskaya, X. Huang, G. Ortiz, J. S. Nosanchuk, J. D. Nosanchuk, and A. Casadevall. 2006. Radiolabeled melanin-binding peptides are safe and effective in treatment of human pigmented melanoma in a mouse model of disease. Cancer Biother Radiopharm 21:117-129
Howell, R. C., E. Revskaya, V. Pazo, J. D. Nosanchuk, A. Casadevall, and E. Dadachova. 2007. Phage display library derived peptides that bind to human tumor melanin as potential vehicles for targeted radionuclide therapy of metastatic melanoma. Bioconjug Chem 18:1739-1748
Schweitzer, A. D., V. Rakesh, E. Revskaya, A. Datta, A. Casadevall, and E. Dadachova. 2007. Computational model predicts effective delivery of 188-Re-labeled melanin-binding antibody to metastatic melanoma tumors with wide range of melanin concentrations. Melanoma Res 17:291-303
Wang, X. G., E. Revskaya, R. A. Bryan, H. D. Strickler, R. D. Burk, A. Casadevall, and E. Dadachova. 2007. Treating cancer as an infectious disease--viral antigens as novel targets for treatment and potential prevention of tumors of viral etiology. PLoS One 2:e1114
Dadachova, E., E. Revskaya, M. A. Sesay, H. Damania, R. Boucher, R. S. Sellers, R. C. Howell, L. Burns, G. B. Thornton, A. Natarajan, G. R. Mirick, S. J. DeNardo, G. L. DeNardo, and A. Casadevall. 2008. Pre-clinical evaluation and efficacy studies of a melanin-binding IgM antibody labeled with 188Re against experimental human metastatic melanoma in nude mice. Cancer Biol Ther 7:1116-1127
Dadachova, E., J. Rivera, E. Revskaya, A. Nakouzi, S. M. Cahill, M. Blumenstein, H. Xiao, D. Rykunov, and A. Casadevall. 2008. In vitro evaluation, biodistribution and scintigraphic imaging in mice of radiolabeled anthrax toxins. Nucl Med Biol 35:755-761
Revskaya, E., A. M. Jongco, R. S. Sellers, R. C. Howell, W. Koba, A. J. Guimaraes, J. D. Nosanchuk, A. Casadevall, and E. Dadachova. 2009. Radioimmunotherapy of experimental human metastatic melanoma with melanin-binding antibodies and in combination with dacarbazine. Clin Cancer Res 15:2373-2379
Rivera, J., A. Nakouzi, N. Abboud, E. Revskaya, D. Goldman, R. J. Collier, E. Dadachova, and A. Casadevall. 2006. A monoclonal antibody to Bacillus anthracis protective antigen defines a neutralizing epitope in domain 1. Infect Immun 74:4149-4156.
Schweitzer, A. D., E. Revskaya, P. Chu, V. Pazo, M. Friedman, J. D. Nosanchuk, S. Cahill, S. Frases, A. Casadevall, and E. Dadachova. 2010. Melanin-covered nanoparticles for protection of bone marrow during radiation therapy of cancer. Int J Radiat Oncol Biol Phys 78:1494-1502
Ballard, B., Z. Jiang, C. E. Soll, E. Revskaya, C. S. Cutler, E. Dadachova, and L. C. Francesconi. 2011. In vitro and in vivo evaluation of melanin-binding decapeptide 4B4 radiolabeled with 177Lu, 166Ho, and 153Sm radiolanthanides for the purpose of targeted radionuclide therapy of melanoma. Cancer Biother Radiopharm 26:547-556
Samanta, D., G. Mukherjee, U. A. Ramagopal, R. J. Chaparro, S. G. Nathenson, T. P. DiLorenzo, and S. C. Almo. 2011. Structural and functional characterization of a single-chain peptide-MHC molecule that modulates both naive and activated CD8+ T cells. Proc Natl Acad Sci USA 108:13682-13687
Lisa Scandiuzzi, Zang Lab
Scandiuzzi, L., K. Ghosh, and X. Zang. 2011. T cell costimulation and coinhibition: genetics and disease. Discov Med 12:119-128
Scandiuzzi, L., W. Beghdadi, E. Daugas, M. Abrink, N. Tiwari, C. Brochetta, J. Claver, N. Arouche, X. Zang, M. Pretolani, R. C. Monteiro, G. Pejler, and U. Blank. 2010. Mouse mast cell protease-4 deteriorates renal function by contributing to inflammation and fibrosis in immune complex-mediated glomerulonephritis. J Immunol 185:624-633
Patel, M., M. Stefanidou, C. B. Long, M. J. Fazzari, L. Tesfa, M. Del Rio, J. Lamour, R. Ricafort, R. P. Madan, and B. C. Herold. 2011. Dynamics of cell-mediated immune responses to cytomegalovirus in pediatric transplantation recipients. Pediatr Transplant (in press)
Varshney, A. K., J. R. Mediavilla, N. Robiou, A. Guh, X. Wang, P. Gialanella, M. Levi, B. N. Kreiswirth, and B. C. Fries. 2009. Diverse enterotoxin gene profiles among clonal complexes of Staphylococcus aureus isolates from the Bronx. Appl Environ Microbiol 75:6839-6849
Varshney, A. K., L. R. Martinez, S. M. Hamilton, A. E. Bryant, M. H. Levi, P. Gialanella, D. L. Stevens, and B. C. Fries. 2010. Augmented production of Panton-Valentine leukocidin toxin in methicillin-resistant and methicillin-susceptible Staphylococcus aureus is associated with worse outcome in a murine skin infection model. J Infect Dis 201:92-96
Varshney, A. K., X. Wang, E. Cook, K. Dutta, M. D. Scharff, M. J. Goger, and B. C. Fries. 2011. Generation, characterization, and epitope mapping of neutralizing and protective monoclonal antibodies against staphylococcal enterotoxin B-induced lethal shock. J Biol Chem 286:9737-9747
Kaltsas, A., A. Guh, J. R. Mediavilla, A. K. Varshney, N. Robiou, P. Gialanellia, M. Henry, M. H. Levi, and B. C. Fries. 2011. Frequency of Panton-Valentine leukocidin-producing methicillin-sensitive Staphylococcus strains in patients with complicated skin and soft tissue infection in Bronx, New York. J Clin Microbiol 49:2992-2995
Schwechter, E. M., D. Folk, A. K. Varshney, B. C. Fries, S. J. Kim, and D. M. Hirsh. 2011. Optimal irrigation and debridement of infected joint implants: an in vitro methicillin-resistant Staphylococcus aureus biofilm model. J Arthroplasty 26:109-113
Wong, K. W., and W. R. Jacobs, Jr. 2011. Critical role for NLRP3 in necrotic death triggered by Mycobacterium tuberculosis. Cell Microbiol 13:1371-1384
Vilcheze, C., B. Weinrick, K. W. Wong, B. Chen, and W. R. Jacobs, Jr. 2010. NAD+ auxotrophy is bacteriocidal for the tubercle bacilli. Mol Microbiol 76:365-377