Einstein/Montefiore Department of Medicine

About: History: Faculty Research: Human Genetics

About: History

Faculty Research:Human Genetics

In the area of Human Genetics, I. Herbert Scheinberg and Irmin Sternlieb conducted studies of copper metabolism and Wilson’s Disease, while also providing patients afflicted with this previously uniformly fatal disease the remarkable benefits of therapy with penicillamine and other decopperizing agents.

Working in their laboratory, Anatol Morell crystallized human ceruloplasmin and provided the earliest insights into how sialated glycoproteins were protected from catabolism, and how desialation fostered the metabolic degradation of serum glycoproteins.

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