Einstein’s Department of Medicine has a distinguished research record with many notable accomplishments during its first quarter-century.
In Cardiology, the studies of Drs. LeJemtel and Sonnenblick and their collaborators provided important insights into understanding the pathophysiology of chronic congestive failure and its treatment.
In Endocrinology, Ora Rosen’s research elucidated aspects of glucose metabolism and the role of protein kinases. She and Norman Fleischer developed one of the country’s first NIH-funded Diabetes Research and Training Centers, whose members have continued to produce a stream of research on the role of insulin, protein kinases, and glucose metabolism. One of Dr. Fleischer’s early faculty recruits was Harry Shamoon, a former resident at Jacobi, who was the Einstein Principal Investigator of the National Diabetes Control and Complications Trial (DCCT), which established that “tight control” of glycemia mitigated the development of microvascular and neuropathic complications in Type 1 Diabetes.
In Atherosclerosis and Lipid Metabolism, Howard Eder and his collaborators, Paul Roheim and Lewis Gidez, made salient contributions to our understanding of lipid metabolism, hyperlipidemic disorders, and the interplay of dietary, genetic, and other factors in those disorders.