Einstein/Montefiore Department of Medicine

2-17-2011: Medicine Grand Rounds

C. difficile Infection: The Role of Fecal Transplantation

Einstein-Montefiore Department of Medicine Grand Rounds

Thursday, February 17, 2011

8:00 am
Forchheimer 1st Floor Lecture Hall, Einstein

12:15 pm
Cherhasky Auditorium, Montefiore


Lawrence J. Brandt, MD

Lawrence J. Brandt, MD
Professor of Medicine (Gastroenterology & Liver Diseases) and Surgery
Emeritus Chief of Gastroenterology

Dr. Lawrence J. Brandt’s research interests include ischemic and vascular disorders of the gastrointestinal system, inflammatory bowel diseases, C. difficile colitis, geriatric gastroenterology, AIDS, and endoscopic technique. Long-standing major interests are the patient-doctor relationship and the way that a patient’s psychological makeup influences his/her illnesses and treatments.

Amongst his contributions are: the performance of the first non-operative gastric polypectomy; the demonstration that gastrointestinal bacteria produce cobamides from dietary vitamin B12 that may inhibit vitamin B12 absorption; that metronidazole can heal and maintain healing of perineal Crohn’s disease; that most cases of newly diagnosed IBD in the elderly are actually ischemic colitis misdiagnosed as ulcerative or Crohn’s colitis; the classification of ischemic colitis and description of its natural history according to site of colonic involvement; the first demonstration of laser-induced regression of Barrett’s epithelium; the development (and U.S. patent) of a cytology balloon [to diagnose infectious esophagitis in AIDS patients]; and use of fecal transplantation to treat chronic and recurring C. difficile colitis.

Dr. Brandt has been on the editorial boards of numerous journals and has authored or edited more than 350 scientific publications and seven books, one of which, Sleisenger and Fordtran’s Gastrointestinal and Liver Disease (8th edition), won first prize in the British Medical Association’s Medical Book Competition, 2007. He currently is Associate Editor for the Focal Points section of Gastrointestinal Endoscopy.

He has received many awards and honors, including the Distinguished Educator Award of the American Gastroenterological Association, the Distinguished Educator Award of the American Society for Gastrointestinal Endoscopy, the Clinical Achievement Award of the American College of Gastroenterology, and the William Dock M.D. Master Teacher Award in Medicine of SUNY, Downstate.

Dr. Brandt is a Master of the American College of Gastroenterology and served on the Board of Trustees of that organization for 13 years, before being elected President of the ACG, 1992-1993. Dr. Brandt has been Visiting Professor at many institutions, has given over 500 lectures nationally and internationally, and is an honorary member of the Puerto Rican, Argentine, and Dominican Republic’s Societies of Gastroenterology.

He is a member of the Davidoff Society of the Albert Einstein College of Medicine in 1990 in recognition of his excellence in teaching, and was named the Montefiore Staff and Alumni Association’s Honoree in 1999. In 2007, he was named Best Teacher in the Department of Medicine by the house-staff. He recently finished 3 terms as a member of the American Board of Internal Medicine (ABIM) subspecialty section in Gastroenterology. Dr. Brandt has been listed every year in Best Doctors in America since 1994, and he has been in Who’s Who in America since 1998.

After receiving his M.D. degree from the State University of New York Health Sciences Center in Brooklyn, Dr. Brandt did his postgraduate medical education at Mount Sinai, including a fellowship in Gastroenterology. He then served in the Army as a gastroenterologist and was stationed in Stuttgart, Germany. After his military discharge, Dr. Brandt joined the staff of Montefiore, where he currently is the Emeritus Chief of Gastroenterology and Professor of Medicine and Surgery at Albert Einstein.

Post-lecture webcast: www.medicinegr.org.
Access code: MEDICINE

This grand rounds is hosted by the Division of Gastroenterology & Liver Diseases.


After attending this activity, participants will:

  1. Understand the recent changes in the epidemiology of C. difficile infection
  2. Know the varied presentations of C. difficile infection
  3. Be aware of how to treat C. difficile infection
  4. Learn how to treat recurrent C. difficile infection and the role of fecal transplantation for recurrent/severe disease


Albert Einstein College of Medicine designates this educational activity for a maximum of 1 credit towards the AMA Physician’s Recognition Award. Each physician should claim only those credits that he/she actually spent in the educational activity.

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