Victor Schuster Named Nephrologist of the Year
Dr. Victor Schuster, Baumritter Professor and University Chairman of the Department of Medicine at Einstein and at Montefiore Medical Center, has been honored by the American Kidney Fund as Nephrologist of the Year.
Image: Victor L. Schuster, MD
Dr. Schuster's research has focused for 25 years on vasoactive hormones and epithelial transport. The Schuster laboratory was the first to show that angiotensin II directly modulates fluid reabsorption by the proximal tubule. For a decade, he worked in acid-base physiology, characterizing the respective transporters of renal collecting duct a and b intercalated cells. In 1995, his laboratory discovered the prostaglandin (PG) transporter "PGT", a finding he has extended to human and mouse genetics, zebrafish, and drug discovery.
The Schuster laboratory has advanced the hypothesis that PG signaling is akin to neuronal signaling, i.e. the signaling molecule is released and then taken up again by the same cell. Because PGT regulates the expression of, and signaling via, PG receptors, it comprises a new therapeutic target for modulating prostanoid signaling.
The NIH has continuously funded Dr. Schuster's research program since 1983. He is currently the PI on an R01 in its 11th year, funded through 2011, and an NIH O'Brien Kidney Center, funded through 2008. In recognition of his research accomplishments, he was elected to the American Society for Clinical Investigation (1992) and the Association of American Physicians (1998).
Dr. Schuster is active in clinical medicine and teaching, serving as the renal consult service attending physician for two months each year. He is a frequent discussant of clinical cases with the house staff, and regularly lectures on renal physiology, pathophysiology, and disease to the Einstein medical students, MD-PhD students, and renal fellows.
The American Kidney Fund fights kidney disease through direct financial support to dialysis patients in need; health education; and prevention efforts.