Einstein/Montefiore Department of Medicine

4-8-10: Medicine Grand Rounds

Translating Airway Gene Expression into a Biomarker for Lung Cancer

Einstein-Montefiore Department of Medicine Grand Rounds

Thursday, April 8, 2010

8:00 am
First Floor Lecture Hall, Forchheimer/Einstein

12:15 pm
Cherkasky Auditorium, Moses/Montefiore

Image: Avrum Spira, MD, MSc


Avrum Spira, MD, MSc
Chief, Division of Computational Biomedicine, Department of Medicine
Associate Professor of Medicine, Pathology and Laboratory Medicine
Adjunct Associate Professor of Bioinformatics
Director, Bioinformatics and Systems Biology Program, Pulmonary Center
Director, Translational Bioinformatics Program, Clinical and Translational Science Institute

Dr. Avrum Spira's research interests focus on applying high-throughput genomic and bioinformatics tools to the translational study of lung cancer and Chronic Obstructive Lung Disease (COPD). He is the Principal Investigator on a number of NIH grants and is active on several NIH Study Sections.

Dr. Spira attends in the Medical Intensive Care Unit at Boston Medical Center.

Dr. Spira received a MD from McGill University and completed his internal medicine residency in Toronto and a fellowship in pulmonary and critical care at Boston University. He has a Master’s degree in bioinformatics, also from Boston University.

This grand rounds is hosted by the Division of Pulmonary Medicine.


After attending this activity, participants will be able to:

  1. Gain insight into the role of microRNA as regulators of the genomic response to smoking in the airway and how airway microRNA expression may serve as a robust biomarker of lung cancer risk
  2. Describe the molecular field of injury in airway epithelium associated with tobacco exposure, and understand how heterogeneity in the airway gene-expression response to smoking can be used as a clinically relevant biomarker for the early detection of lung cancer


Albert Einstein College of Medicine designates this educational activity for a maximum of 1 credit towards the AMA Physician’s Recognition Award. Each physician should claim only those credits that he/she actually spent in the educational activity.


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Albert Einstein College of Medicine
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