Einstein/Montefiore Department of Medicine

In The Media

CNN.com interviews Dr. Joseph Sparano about the FDA's controversial decision to phase out the drug Avastin as a treatment for metastatic breast cancer. The FDA says Avastin's side effects outweigh potential benefits for those with metastatic cancer. Dr. Sparano notes the announcement still allows doctors to prescribe Avastin for metastatic breast cancer, but only for those who can afford it, rather than those who medically could benefit from it. The FDA announcement does not affect Avastin's status as an approved therapy for lung, kidney, colorectal and brain cancers. Dr. Sparano is professor of medicine (oncology) and of obstetrics & gynecology and women's health. (Friday, December 17, 2010)

Dr. Sparano's Profile
Bloomberg highlights research by Joseph Sparano, M.D., that found obese women who have a type of breast cancer fueled by estrogen are more likely to die of the disease than their slimmer peers. Dr. Sparano notes that breast cancer patients who are already overweight or obese should make an effort to avoid further weight gain and that they should get nutritional evaluations. Dr. Sparano is professor of medicine and of obstetrics & gynecology and women's health and associate chair of oncology at Montefiore Medical Center. (Thursday, December 09, 2010)

Dr. Sparano's Profile
Science News interviews Arturo Casadevall, M.D., Ph.D., about his new research, developed with Aviv Bergman, Ph.D., which provides a mathematical model to support Dr. Casadevall's theory that warm-blooded mammals evolved to defend against fungal infections. The novel model shows that the optimum body temperature for organisms to ward off fungal infections without burning too much energy is 36.7° Celsius, which is close to the core body temperatures of mammals, including humans. Dr. Casadevall is professor and the Leo and Julia Forchheimer Chair in Microbiology and Immunology. Dr. Bergman is professor and founding chair of systems and computational biology. (Tuesday, December 07, 2010)

Dr. Casadevall's Profile
WebMD interviews Michal Melamed, M.D., regarding new guidelines by the Institute of Medicine (IOM) that call for increasing the recommended dietary allowances of vitamin D and calcium. The IOM recommends that most Americans should consume 600-800 international units of vitamin D a day to optimize bone health. Dr. Melamed states that the new guidelines recommend a level of vitamin D that will keep people out of the deficiency range. The IOM discourages the use of high dose vitamin D supplements, however. Dr. Melamed is assistant professor of medicine and of epidemiology & population health. (Tuesday, November 30, 2010)

Dr. Melamed's Profile
The New York Daily News interviews Nir Barzilai, M.D., and researcher William Greiner, R.N., M.S., regarding the Longevity Genes Project, a genetics study of 500 centenarians, about the role genes play in longevity. Dr. Barzilai notes that the centenarians in the study seem to have genetic traits that delay age-related diseases. The story also profiles several of the participants in the Longevity Genes Project and highlights SuperAgers.com, a new website about the study. Dr. Barzilai is the Ingeborg and Ira Leon Rennert Chair of Aging Research and director of both the Institute for Aging Research and the Nathan Shock Center of Excellence in the Basic Biology of Aging. (Monday, November 22, 2010)

Dr. Barzilai's Profile
MSN features Jill Crandall, M.D., in an article that dispels some current myths about insulin therapy. Dr. Crandall notes that insulin injections can be a lifesaving therapy for both type 1 and type 2 diabetics, who cannot control the disease with diet and exercise alone, and discusses the changes in insulin delivery methods, including finer needles and injector pens, that are making insulin dosage more convenient and less painful than ever before. Dr. Crandall is associate professor of clinical medicine. (Wednesday, November 03, 2010)

Dr. Crandall's profile
U.S. News & World Report (via Healthday) features comments by Roman Perez-Soler, M.D., on an experimental cancer drug that is proving effective in treating some lung cancers. A recently released study showed that the drug, crizotinib, seemed to work well in patients whose tumors had a specific genetic mutation. Dr. Perez-Soler notes that while this is promising, there could be so many different genotypes that it would be impractical to come up with drugs targeting all of them. Dr. Perez-Soler is professor of medicine at Einstein and chief of oncology at the Montefiore-Einstein Center for Cancer Care. (Wednesday, October 27, 2010)

Dr. Perez-Soler's Profile
Nature.com features comments by John Greally, M.B., B.Ch., Ph.D, about the Roadmap Epigenomics Project and its effort to identify and map all the chemical tags, known collectively as the human epigenome, that control the activities of genes. Dr. Greally notes that although having the complete mapping information is valuable overall, the data may be tricky to utilize for most researchers when studying specific diseases. Dr. Greally is an associate professor of genetics and of medicine and the Faculty Scholar for Epigenomics. (Thursday, October 07, 2010)

Dr. Greally's Profile
Caring.com, a leading online destination for information about caring for aging loved ones, interviews Laurie Jacobs, M.D., regarding the top fears men and women have about aging. Dr Jacobs, a geriatrician, notes that a woman's fear about her appearance persists no matter her age and that men worry about impotence and loss of identity during retirement. Dr. Jacobs is director of the Jack and Pearl Resnick Gerontology Center. (Thursday, October 07, 2010)

Dr. Jacobs' Profile
Der Spiegel, Germany's leading weekly news magazine, interviews Nir Barzilai, M.D., regarding his genetics research on centenarians. Dr. Barzilai notes that these "super agers" are genetically in a class by themselves, since environmental and lifestyle factors do not appear to affect their longevity. The story also profiles several of the participants in his study of more than 500 centenarians and their offspring discussing their extraordinarily long lives. Dr. Barzilai is the Ingeborg and Ira Leon Rennert Chair of Aging Research and director of the Institute for Aging Research. (Friday, September 24, 2010)

Dr. Barzilai's Profile
The Associated Press highlights a recent study by Michael Alderman, M.D., about new ways to treat hypertension that might help optimize patient care. The study found that measuring blood levels of the hormone renin may assist doctors in determining which blood pressure medicine their patients should take. The research also found that in some cases taking a drug that's a poor match to that hormone can actually trigger a spike in blood pressure. Dr. Alderman is professor of epidemiology & population health and of medicine and the Atran Foundation Chair in Social Medicine. (Tuesday, September 07, 2010)

Dr. Alderman's Profile
The Wall Street Journal features news of a study by Michael Alderman, M.D. which aims to help provide scientific guidelines to help doctors prescribe appropriate medication for high blood pressure. Doctors have known for years that patients with different physical characteristics respond differently to various hypertension drugs. Dr. Alderman's study focused on using the hormone renin as a biomarker for matching the correct drugs to the individual patient. Dr. Alderman is professor of epidemiology & population health and of medicine and the Atran Foundation Chair in Social Medicine. (Tuesday, August 24, 2010)

Dr. Alderman's profile
CNN features comments from Chaim Putterman, M.D., on why women may experience chronic pain more intensely than men. He notes that a woman's hormones may influence the severity of pain. Though men and women deal with pain differently, many doctors treat them the same for conditions such as rheumatoid arthritis. He also notes the correlation between chronic pain and depression and the need to treat both issues simultaneously to improve quality of life in patients living with chronic pain conditions. Dr. Putterman is chief of the division of rheumatology and professor of medicine and of microbiology & immunology. (Friday, August 13, 2010)

Dr. Putterman's Profile
The New York Times interviews Nir Barzilai, M.D., about a new study published in Science that identifies a set of 150 genetic variants that predicts extreme longevity with 77 percent accuracy. Dr. Barzilai notes that these genes provide protection against all the diseases of old age, a more powerful strategy than tackling each disease one by one. Dr. Barzilai is the Ingeborg and Ira Leon Rennert Professor of Aging Research and director of Einstein's Institute for Aging Research. (Thursday, July 01, 2010)

Dr. Barzilai's Profile
U.S. News & World Report (via Science News) features Jill Crandall, M.D., and her pilot study, which indicates that resveratrol, the substance widely known to be found in red wine and thought to impart health benefits, improves insulin resistance. Dr. Crandall emphasized that while the results of her small study were promising, they are preliminary and the benefits of resveratrol remain unproven. Dr. Crandall is associate professor of clinical medicine. (Tuesday, June 29, 2010)

Dr. Crandall's profile
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