Einstein/Montefiore Department of Medicine

Grand Rounds

A New Paradigm for Evaluation and Management of "Difficult" Asthma: The Role of Phenotypes

Einstein/Montefiore Department of Medicine Grand Rounds

Thursday, October 18, 2012

8:00 AM: Forchheimer Medical Science Building 3rd Fl Lecture Hall

Speaker & Info

Sally E. Wenzel, MD
Professor of Medicine
Director, University of Pittsburgh Asthma Institute
UPMC/Univ of Pittsburgh School of Medicine
Pulmonary, Allergy and Critical Care Medicine



Repeated at 12:15 pm, Cherkasky Auditorium, Montefiore Medical Center

Dr. Sally Wenzel began her translational research career in the area of asthma in the mid 1980s, while a pulmonary fellow at the Medical College of Virginia. She moved to National Jewish in Denver in 1987 where she remained for nearly 20 years. She was one of the first investigators to perform invasive (bronchoscopic) studies of asthma and has continued performing pathophysiologic studies of asthma and severe asthma ever since. She became focused on severe asthma 10 years ago and is considered an expert in understanding and treating this group of patients. Her efforts led to recognition that severe asthma is a “real” problem impacting 5-10% of the asthma population. She organized an American Thoracic Society Workshop which developed a definition for severe asthma which is now widely accepted as the definition of severe asthma. 

In addition to her pathophysiologic studies of asthma and severe asthma, Dr. Wenzel utilizes cell systems derived from severe asthmatics, particularly those involving fibroblasts and epithelial cells. She is continuing these studies, as well as pathophysiologic studies of asthma at the University of Pittsburgh where she is currently Professor of Medicine and Director of the University of Pittsburgh Asthma Institute  at UPMC/UPSOM. 

Nationally, Dr. Wenzel has published over 100 peer reviewed papers. She has been active in the American Thoracic Society and served as deputy editor for the American Journal of Respiratory and Critical Care Medicine. She served as a member of the NHLBI Internal Board of Scientific Counselors from 2003-2007 and is currently on the Lung Cellular and Molecular Immunology study section. In 2006, she was given the National Jewish Faculty Award for Scientific Achievement, being recognized for her contributions to the understanding of severe asthma. She received the Elisabeth Rich MD Award for serving as a role model of women in medicine/science and received the ATS 2010 Recognition Award for Scientific Accomplishments. 


Objectives - After attending this activity, participants will be able to: 

  1. Use objective measures to diagnose and evaluate "Difficult Asthma"
  2. Understand the concept of phenotyping in disease and apply it to asthma 
  3. Identify asthma phenotypes and use them to guide therapy


Accreditation: Albert Einstein College of Medicine designates this educational activity for a maximum of 1 credit towards the AMA Physician's Recognition Award. Each physician should claim only those credits that he/she actually spent in the educational activity.

Host: Department of Medicine (Division of Pulmonary Medicine)

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