Einstein/Montefiore Department of Medicine

Grand Rounds

Medicine Grand Rounds: Insights into the Diagnosis, Management and Mechanisms of COPD

Einstein/Montefiore Department of Medicine Grand Rounds

Thursday, January 21, 2016

8:00 AM: Forchheimer Medical Science Building 3rd Floor Lecture Hall

Speaker & Info

Robert Foronjy, MD
Chief, Pulmonary and Critical Care, SUNY Downstate Medical Center
Visiting Assistant Professor, Department of Medicine (Critical Care), Montefiore Einstein

Repeated at 12:15 pm, Cherkasky Auditorium, Montefiore Medical Center.

Dr. Robert Foronjy completed a medical degree at Temple Medical School, and an internal medicine residency and pulmonary and critical care fellowship at Columbia University Medical Center. He joined the faculty at Columbia in 2001 and began a career in basic and translational science. This research focused on better understanding the pathogenesis of chronic obstructive pulmonary disease (COPD). During his time at Columbia, he developed both genetic and disease exposure models in mice to study the underlying causes of COPD. Using these animal models, Foronjy and colleagues showed for the first time that a lung antioxidant, superoxide dismutase-1, could protect against smoke-induced inflammation and emphysema formation thus establishing the therapeutic potential of antioxidants for this disease.

Dr. Foronjy's work on redox biology of the lung was awarded an NIH grant and, in 2011, he was recruited to become the Director of Lung Research at St. Luke's Roosevelt Medical Center. Over the next several years he and his colleagues demonstrated that antioxidants mediate their protective effects by increasing protein phosphatase 2A (PP2A) activity in the lung. Furthermore, they showed that the serum protein alpha one antitrypsin acts via PP2A to counter the inflammatory and proteolytic processes that result in the development of COPD. These studies established novel anti-inflammatory effects for both PP2A and A1AT in the lung.

In 2015, Dr. Foronjy became Chief of Pulmonary and Critical Care Medicine at SUNY Downstate Medical Center, where his research group continues to work to identify the basic mechanisms of lung injury in COPD and other pulmonary diseases in order to develop better treatments for patients in the future.

Objectives - After attending this activity, participants will be able to:

  1. Understand the health care impact of COPD in the US
  2. Appreciate the proper diagnostic approaches for categorizing and detecting COPD
  3. Know the latest advancements in the treatment of management of COPD
  4. Comprehend the underlying mechanisms of COPD development
  5. Have insight into a novel new disease model that provides an enhanced understanding of the role of nicotine in COPD development

Accreditation: Albert Einstein College of Medicine designates this educational activity for a maximum of 1 credit towards the AMA Physician's Recognition Award. Each physician should claim only those credits that he/she actually spent in the educational activity. Albert Einstein College of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Host: Division of Pulmonary Medicine (Department of Medicine)

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