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About the Division
Faculty:
Philip D. Lief, MD
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Sharon Silbiger, M.D.
Division of Nephrology
Sharon Silbiger, M.D.
Lei, J., Silbiger, S., Ziyadeh, F., Neugarten, J.: Serum-stimulated _
1
type IV collagen gene transcription is mediated by TGF_ and inhibited by estradiol. Am J Physiol. 274:F252 -258, 1998.
Silbiger, S., Lei, J., Ziyadeh, F.N., Neugarten, J.,: Estradiol reverses TGF_-1 - stimulated type IV collagen synthesis in murine mesangial cells. Am J Physiol. 274:F1113 - 1118, 1998.
Silbiger, S., Lei, J., Neugarten, J: Estradiol suppresses type I collagen synthesis in mesangial cells via activation of AP-1. Kidney Int. 55:1268-1276, 1999.
Neugarten, J., Medve, I., Lei, J., Silbiger, S.: Estradiol suppresses mesangial cell type I collagen synthesis via activation of the mitogen activated protein kinase cascade. Am J Physiol. 277:F875-881, 1999.
Neugarten J, Gallo G, Silbiger S. Kasiske B: Glomerulosclerosis in aging human is not influenced by gender. Am J Kidney Disease. 34:884-888, 1999.
Neugarten J. Acharya A, Silbiger S. Effect of gender on the progression of non-diabetic renal disease: a meta-analysis. J Am Soc Nephrol. 11:319-329, 2000.
Neugarten J, Acharya A, Lei J, Silbiger S. Selective estrogen receptor modulators suppress mesangial cell collagen synthesis. Am J Physiol. 279:F309-18; 2000.
Zdunek, M., Silbiger S., Lei, J., Neugarten, J., Protein kinase CK2 mediates TGF-β1-stimulated type IV collegen gene transcription and its reversal by estradiol. Kidney Int. 60:2097-2108, 2001.
Guccione, M., Silbiger S., Lei, J., Neugarten, J., Estradiol upregulates mesangial cell metalloproteinase-2 activity via the transcription factor AP-2 Am J Physiol. 282:F164-169, 2002.
Neugarten, J., Kasiske, B., Silbiger, S., Nyengaard J.R., Effects of sex on renal structure. Nephron. 90:139-144, 2002.
Negulescu, O., Bognar, I., Lei, J., Devarajian, P., Silbiger, S., Neugarten, J., Estradiol reverses TGF-β1-induced mesangial cell apoptosis by a casein kinase II- dependant mechanism. Kidney Int. 62:1989-1998, 2002.
Silbiger, S., Neugarten, J., The role of gender in the progression of renal disease. In. Adv Ren Replacement Ther. 10:3-14, 2003.
Blush, J., Lei, J., Pullman, J., Ju, W.J., Silbiger, S., Neugarten, J., Estradiol reverses renal injury in transgenic Alb/TGFβ mice. Kidney Int. 66:2148-2154, 2004.
Neugarten J, Silbiger S. Estrogen and the progression of renal disease. In Recent Research developments in Physiology. Ed. SG Pandali, Research Signpost, Kerala, India, 2004
Silbiger S. Practice Point Commentary on Miller JA et al. (2006) J Am Soc Nephrol 17:2554-2560.
Silbiger, S. Renal hemodynamic responses to renin-angiotensin blockade differ in men and women. Nat Clin Pract Nephrol 3: 68-9, 2007
Silbiger S, Neugarten J. Gender and human renal disease. Gender Med. In press, 2008.
Interim Division Chief
Vaughn Folkert, M.D
(
bio
)
Professor of Clinical Medicine
Nephrology Conferences
2012-2013 Schedule
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