Division of Infectious Diseases

Infectious Diseases Creates Toolkit to Fight KPC Superbug

Klebsiella pneumoniae
Photo: Klebsiella pneumoniae
Dan Forbes, wired.com

May 20, 2014 - BRONX, NY - Carbapenemase-producing Klebsiella pneumoniae (KPC), an extensively antibiotic-resistant superbug, has caused many lethal healthcare-associated infections in recent years. The Centers for Disease Control and Prevention (CDC) reports that while still uncommon, KPC kills up to half of people who get severe infections from it.

Montefiore Medical Center and Boston University School of Public Health have partnered to create a toolkit to help prevent and control the emergence and spread of KPC in healthcare settings. Prepared by Dr. Brian Currie, Assistant Dean for Clinical Research at Montefiore and Professor of Clinical Medicine (Infectious Diseases) and of Clinical Epidemiology & Population Health at Einstein; Dr. Victoria Parker, Associate Professor of Health Policy & Management at Boston University; and Caroline Logan, MPH, Research Project Coordinator at Boston University; the Carbapenem-Resistant Enterobacteriaceae (CRE) Control and Prevention Toolkit was funded by the U.S. Department of Health and Human Services' Agency for Healthcare Research and Quality (AHRQ). The toolkit provides intervention guidelines for healthcare professionals, acute- and long-term-care hospitals, and health departments nationwide. download the toolkit 

Dr. Brian Currie, infectious diseases and antimicrobial stewardship specialist, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY
Brian Currie, MD, MPH

According to Dr. Currie, the toolkit guides clinicians through the process of implementing an intervention, with practical, customizable tools such as hand hygiene compliance and promoting antibiotic stewardship. Montefiore's protocol, which detects KPC with a rapid molecular lab test and initiates contact isolation for all positive patients, has virtually eliminated patient-to-patient transmission of KPC as a result of implementing the toolkit measures.

"The appearance of KPC in healthcare settings is a serious challenge to all medical professionals and it's an area that requires significant attention to ensure patient safety," said Dr. Currie. "Our goal is to share our successful KPC interventions to help other institutions establish effective prevention programs."

More info: Fight Against Healthcare-Associated Infections Supported Through New Toolkit 

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