Areas of Research: Thrombosis and Hemostasis (epidemiological & clinical studies); Women's Blood Disorders, particularly the prothrombotic state of pregnancy; transgenic sickle cell mouse models.
Dr. Henny Billett has been Chief of the Division of Hematology since 2012 and Professor of Clinical Medicine and Pathology since 2002.
Dr. Billett's clinical research interests are in risk factors for thrombosis and microvascular disease, with emphasis on epidemiological aspects and outcomes research. Her investigations focus on the effect of race and ethnicity on thrombosis in general and, in particular, the thrombotic and microvascular complications of sickle cell disease.
Recent investigations have focused on:
- Hemolysis patterns in CF-LVAD patients and their association with device thrombosis (collaboration with Dr. Ulrich Jorde, Cardiology)
- Evaluation of CNS function and cognition in patients with sickle cell disease (collaboration with Dr. Craig Branch, Gruss Magnetic Resonance Research Center)
- Priapism in murine and human models of sickle cell (collaboration with Dr. Kelvin Davies)
- Multicenter studies
- P-Selectin therapy in sickle cell disease
- Viral co-infections, paraproteinemia and thrombosis
Dr. Billett completed an undergraduate degree from the University of Pennsylvania cum laude; medical school Mount Sinai School of Medicine; and an MSc from the London School of Hygiene and Tropical Medicine in London. She was a Senior House Officer at St. Bartholomew's Hospital, London, and completed her training at Montefiore.
- Park D, Southern W, Calvo M, Kushnir M, Solorzano C, Sinnett M, Billett HH. Treatment with Dalteparin is Associated with a Lower Risk of Bleeding Compared to Treatment with Unfractionated Heparin in Patients with Renal Insufficiency. J Gen Intern Med. 2016; 31(2):182-7. PubMed [journal]PMID: 26209179 PMCID: PMC4720650
- Jou, E, Glichich G, Chan ACY, Mohan D, Felson UR, Ayyappan S, Billett HH, Hui E, Chan ATC, Raghupathy R. Viral Co-Infections and Paraproteins in HIV: Effect on Development of Hematological Malignancies. Ann Hematol. 2016 Jan 9. [Epub ahead of print] PMID: 26747296
- Broder A, Mowrey W, Kim M, Murakhovskaya I, Billett HH, Neugarten J, Costenbader KH, Putterman C.Association between Antiphospholipid Antibodies and All-Cause Mortality among End-Stage Renal Disease Patients with and without SLE: a retrospective cohort study. Rheumatology 2015 Dec 24. pii: kev423. [Epub ahead of print] PubMed PMID: 26705328.
- Naymagon H, Pendurti G, Billett HH. Acute Splenic sequestration crisis in adult sickle cell disease: A report of 16 cases. Hemoglobin. 2015;39:375-9.
- Curtis SA, Etzion Z, Danda NA, Cohen HW, Billett HH. Elevated steady state WBC and platelet counts are associated with frequent emergency room use in adults with sickle cell anemia. PLoS One.
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