Harry Shamoon, M.D.
Dr. Shamoon is Professor of Medicine (Endocrinology, Diabetes and Metabolism), Associate Dean for Clinical & Translational Research, and director of the Harold and Muriel Block Institute for Clinical & Translational Research at Einstein and Montefiore.
Dr. Shamoon's laboratory has studied the mechanisms and treatment for defective counterregulation of hypoglycemia in type 1 diabetes. He and colleagues established the fundamental link between reduced epinephrine and glucagon secretion and impaired hepatic glucose production in response to hypoglycemia. Further studies elucidated the stimulus-specificity of the responses to hypoglycemia and the resultant defects in glucose counterregulation, the existence of hepatic "autoregulation" by glucose per se, and the role of glucokinase activation in restoring impaired counterregulation in diabetes. His group has also established the contributions of hepatic glycogen metabolism and gluconeogenesis to glucose counterregulation in humans using in vivo MR spectroscopy. In addition, Dr. Shamoon directed major clinical trials at Einstein such as the Diabetes Control and Complications Trial, the landmark study that established the benefits of intensive glycemic control in type 1 diabetes, and the Diabetes Prevention Program in type 2 diabetes. Dr. Shamoon has been elected to the American Society of Clinical Investigation (1992), the American Association of Physicians (1998), and the New York Academy of Medicine (2003).
More Information About Dr. Harry Shamoon
Harold and Muriel Block Institute for Clinical and Translational Research at Einstein and Montefiore
Diabetes Research Center
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