The New York City Research and Improvement Networking Group (NYC RING)

TLC-Plus: A study to evaluate the feasibility of an enhanced test, link to care, plus treat approach for HIV Prevention in the United States

This project is a randomized clinical trial which will use several components to evaluate the feasibility and effectiveness of an enhanced community-level test, link to care, plus treat strategy in the United States.

Participating Practices
Montefiore Medical Center sites in Bronx, NY - Moses Division, Weiler Division, North Division, and Off-Site Clinics

Albert Einstein College of Medicine- Division of Substance Abuse

Principal Investigator
Barry Zingman, MD

Project Timeline
Launch: January 2011
Data Collection:
Project Period Start/End: January 1, 2011 – December 31, 2013

Study Overview
The main purpose of this study is to evaluate the feasibility of an enhanced community-level test, link to care, plus treat strategy in the United States. The study includes the following components: Expanded Human Immunodeficiency Virus (HIV) Testing, Linkage-to-Care, Viral Suppression, Prevention for Positives, and Patient and Provider Surveys. The Expanded HIV Testing component involves social mobilization with targeted messaging to promote testing and implementation of the universal offer of HIV testing in emergency departments (EDs) and hospital inpatient admissions. The Linkage-to-Care and Viral Suppression components involve site randomization to test the effectiveness of a financial incentive (FI) intervention compared with the standard of care (SOC). The Prevention for Positives component uses individual randomization to compare the SOC plus a computer-delivered intervention with the SOC. The Patient and Provider Surveys will be administered at specific time points during the study to assess knowledge, attitudes and practices regarding early initiation of antiretroviral therapy (ART) and the FI interventions. The study will take place over 36 months and will be conducted in two intervention communities (Bronx, New York and Washington, D.C.). Surveillance data from these communities will be compared with that from four non-intervention communities (Chicago, Illinois; Houston, Texas; Miami, Florida; and Philadelphia, Pennsylvania).

Contact information:
Paul Meissner, MSPH, Administrator , pmeissne@montefiore.org

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