Department of Cell Biology
Price Bldg., Room 102
Dr. Ito’s faculty page
Stem Cell Institute
Our research interests have focused on biomedical research aiming toward the development of stem cell therapies. In keeping with this commitment, our team’s long-term research goals are to define the critical regulatory pathways in the controlled self-renewal of stem cells in hematopoiesis.
One of our main projects is to illuminate through both genetic and pharmacological approaches the role of one such potential regulatory element, cellular metabolism, in the cell fate decisions of self-renewing hematopoietic stem cells (HSCs). Various molecular metabolisms have recently come into focus as novel regulatory elements of stem cell maintenance.
Another study in the laboratory is investigating the pathogenesis of an incurable stem cell disorder, myelodysplastic syndrome (MDS). Our lab has devised a plan to identify key mechanisms of MDS pathogenesis for the development of targeted therapies to combat the disease more effectively.